PDB ID: 1A2Y
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Structure summary
Code : | 1A2Y PDBj RCSB PDB PDBe | ||||||||||||||||||||||||||||||||||||
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Header : | COMPLEX (IMMUNOGLOBULIN/HYDROLASE) | ||||||||||||||||||||||||||||||||||||
Title : | HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3 | ||||||||||||||||||||||||||||||||||||
Release Data : | 1998-04-29 | ||||||||||||||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Tsuchiya, D., Mariuzza, R.A. | ||||||||||||||||||||||||||||||||||||
Keywords : | COMPLEX (IMMUNOGLOBULIN-HYDROLASE), IMMUNOGLOBULIN V REGION, HYDROLASE, GLYCOSIDASE, BACTERIOLYTIC ENZYME, EGG WHITE, COMPLEX (IMMUNOGLOBULIN-HYDROLASE) complex | ||||||||||||||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.5 Å ) | ||||||||||||||||||||||||||||||||||||
Citation : |
A mutational analysis of binding interactions in an antigen-antibody protein-protein complex.
Dall'Acqua, W.,Goldman, E.R.,Lin, W.
et al.
PubMed: 9609690 Hydrogen Bonding and Solvent Structure in an Antigen-Antibody Interface. Crystal Structures and Thermodynamic Characterization of Three Fv Mutants Complexed with Lysozyme
Fields, B.A.,Goldbaum, F.A.,Dall'Acqua, W.
et al.
Bound Water Molecules and Conformational Stabilization Help Mediate an Antigen-Antibody Association
Bhat, T.N.,Bentley, G.A.,Boulot, G.
et al.
Solvent Rearrangement in an Antigen-Antibody Interface Introduced by Site-Directed Mutagenesis of the Antibody Combining Site
Ysern, X.,Fields, B.A.,Bhat, T.N.
et al.
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Reaction
Chain : | A |
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UniProt : | P01635 (KV5A3_MOUSE) |
Reaction : | - |
Chain : | B |
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UniProt : | P01820 (HVM44_MOUSE) |
Reaction : | - |
Chain : | C | ||||||||
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UniProt : | P00698 (LYSC_CHICK) | ||||||||
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