Het-PDB Navi2 (PDB: 1A2E)

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Ligands
Code	Name		Style	Show	Link
CPT	Cisplatin				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1A2E

Code :

1A2E PDBj RCSB PDB PDBe

Header :

DNA

Title :

CRYSTAL STRUCTURE OF A DOUBLE-STRANDED DNA DECAMER CONTAINING A CISPLATIN INTERSTRAND CROSS-LINK ADDUCT

Release Data :

1999-04-12

Compound :

mol_id	molecule	chains
1	DNA (5'-D(CPCPTPCPGPCPTPCPTPC)-3')	A
	other_details: PT(CPT) CROSSLINKS N7(G5) AND N7(G15)

mol_id	molecule	chains
2	DNA (5'-D(GPAPGPAPGPCPGPAPGPG)-3')	B
	other_details: PT(CPT) CROSSLINKS N7(G5) AND N7(G15)

Source :

mol_id	organism_scientific
1
	synthetic: yes

mol_id	organism_scientific
2
	synthetic: yes

Authors :

Coste, F., Zelwer, C.

Keywords :

ANTITUMOR DRUG, CIS-DDP, INTERSTRAND CROSS-LINK, DNA

Exp. method :

X-RAY DIFFRACTION ( 1.63 Å )

Citation :

Crystal structure of a double-stranded DNA containing a cisplatin interstrand cross-link at 1.63 A resolution: hydration at the platinated site.

Coste, F.,Malinge, J.M.,Serre, L. et al.
(1999) Nucleic Acids Res. 27 : 1837 - 1846

PDB ID: 1A2E