Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
BIS 1,1,5,5-tetrafluorophosphopentylphosphonic acid adenylate ester
EPE 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid
Code : 16PK
Header : KINASE
Title : PHOSPHOGLYCERATE KINASE FROM TRYPANOSOMA BRUCEI BISUBSTRATE ANALOG
Release Data : 1998-11-25
Compound :
mol_id molecule chains synonym
1 3-PHOSPHOGLYCERATE KINASE A PGK
ec: 2.7.2.3
mutation: TRUNCATION OF T. BRUCEI SPECIFIC C-TERMINAL SEQUENCE
Source :
mol_id organism_scientific expression_system
1 Trypanosoma brucei  (taxid:5691) Escherichia coli BL21  (taxid:511693)
variant: GLYCOSOMAL VERSION
organelle: GLYCOSOME
expression_system_strain: BL21
expression_system_vector_type: PLASMID
expression_system_plasmid: PET21A
Authors : Bernstein, B.E., Bressi, J., Blackburn, M., Gelb, M., Hol, W.G.J.
Keywords : KINASE, PHOSPHOGLYCERATE, TERNARY COMPLEX, GLYCOLYSIS, TRANSFERASE, BISUBSTRATE, ANALOG
Exp. method : X-RAY DIFFRACTION ( 1.6 Å )
Citation :

A bisubstrate analog induces unexpected conformational changes in phosphoglycerate kinase from Trypanosoma brucei.

Bernstein, B.E.,Williams, D.M.,Bressi, J.C.  et al.
(1998)  J.Mol.Biol.  279 : 1137 - 1148

PubMed: 9642090
DOI: 10.1006/jmbi.1998.1835

Chain : A
UniProt : P07378 (PGKC_TRYBB)
Reaction : ATP + 3-phospho-D-glycerate = ADP + 3-phospho- D-glyceroyl phosphate.