Brand  (β version)

PDB ID: 12CA

Hetero Atom Contents

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
HG Mercury (II) ion PoSSuM
ZN Zinc ion PoSSuM

Structure summary

Code : 12CA
Header : LYASE(OXO-ACID)
Title : ALTERING THE MOUTH OF A HYDROPHOBIC POCKET. STRUCTURE AND KINETICS OF HUMAN CARBONIC ANHYDRASE II MUTANTS AT RESIDUE VAL-121
Release Data : 1992-10-15
Compound :
mol_id molecule chains
1 CARBONIC ANHYDRASE II A
ec: 4.2.1.1
Source :
mol_id organism_scientific organism_common
1 Homo sapiens  (taxid:9606) Human
Authors : Nair, S.K., Christianson, D.W.
Keywords : LYASE(OXO-ACID)
Exp. method : X-RAY DIFFRACTION ( 2.4 Å )
Citation :

Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase II mutants at residue Val-121.

Nair, S.K.,Calderone, T.L.,Christianson, D.W.  et al.
(1991)  J.Biol.Chem.  266 : 17320 - 17325

PubMed: 1910042

Reaction

Chain : A
UniProt : P00918 (CAH2_HUMAN)
Reaction : H(2)CO(3) = CO(2) + H(2)O.