Brand  (β version)
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MTX

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Hetero-Atom Name Methotrexate
Synonym -
Code MTX
Formula C20 H22 N8 O5
Similar Hetero-Atom 20 Hetero-Atoms
Links DrugBank   DB00563  
KEGG Drug   D00142  
KEGG Compound   C01937  
PDB Ligand   PDBj   RCSB PDB
Code 1AO8
TitleDIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES
SouceLactobacillus casei
Code 1AXW
TitleE. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH METHOTREXATE (MTX) AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)
SouceEscherichia coli
Code 1D1G
TitleDIHYDROFOLATE REDUCTASE FROM THERMOTOGA MARITIMA
SouceThermotoga maritima
Code 1DDR
TitleMOLECULE: DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH METHOTREXATE AND UREA
SouceEscherichia coli
Code 1DDS
TitleMOLECULE: DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH METHOTREXATE
SouceEscherichia coli
Code 1DF7
TitleDIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND METHOTREXATE
SouceMycobacterium tuberculosis
Code 1DHI
TitleLONG-RANGE STRUCTURAL EFFECTS IN A SECOND-SITE REVERTANT OF A MUTANT DIHYDROFOLATE REDUCTASE
SouceEscherichia coli
Code 1DHJ
TitleLONG-RANGE STRUCTURAL EFFECTS IN A SECOND-SITE REVERTANT OF A MUTANT DIHYDROFOLATE REDUCTASE
SouceEscherichia coli
Code 1DLS
TitleMETHOTREXATE-RESISTANT VARIANTS OF HUMAN DIHYDROFOLATE REDUCTASE WITH SUBSTITUTION OF LEUCINE 22: KINETICS, CRYSTALLOGRAPHY AND POTENTIAL AS SELECTABLE MARKERS
SouceHomo sapiens (human)
Code 1DRA
TitleCRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
SouceEscherichia coli