Brand  (β version)
from 3h4g  [Download mmcif  mol
FID

created by OpenBabel

Hetero-Atom Name (2s,4s)-2-aminoformyl-6-fluoro-spiro[chroman-4,4'-imidazolidine]-2',5'-dione
Synonym fidarestat
Code FID
Formula C12 H10 F N3 O4
Similar Hetero-Atom 4 Hetero-Atoms
Links DrugBank   DB02021  
KEGG Drug   D01842  
PDB Ligand   PDBj   RCSB PDB
Code 1EF3
TitleFIDARESTAT BOUND TO HUMAN ALDOSE REDUCTASE
SouceHomo sapiens (human)
Code 1PWM
TitleCrystal structure of human Aldose Reductase complexed with NADP and Fidarestat
SouceHomo sapiens (human)
Code 2AGT
TitleAldose Reductase Mutant Leu 300 Pro complexed with Fidarestat
SouceHomo sapiens (human)
Code 2PD9
TitleHuman aldose reductase mutant V47I complexed with fidarestat.
SouceHomo sapiens (human)
Code 2PDW
TitleHuman aldose reductase mutant C303D complexed with fidarestat.
SouceHomo sapiens (human)
Code 2PDY
TitleHuman aldose reductase double mutant S302R-C303D complexed with fidarestat.
SouceHomo sapiens (human)
Code 2PEV
TitleComplex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution exceeds concentration of IDD594.
SouceHomo sapiens (human)
Code 2PF8
TitleComplex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution is equal to concentration of IDD594.
SouceHomo sapiens (human)
Code 2PFH
TitleComplex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution is less than concentration of IDD594.
SouceHomo sapiens (human)
Code 3H4G
TitleStructure of aldehyde reductase holoenzyme in complex with potent aldose reductase inhibitor Fidarestat: Implications for inhibitor binding and selectivity
SouceSus scrofa (pigs)