Brand  (β version)
from 3zos  [Download mmcif  mol
0LI

created by OpenBabel

Hetero-Atom Name 3-(imidazo[1,2-B]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide
Synonym ponatinib
Code 0LI
Formula C29 H27 F3 N6 O
Similar Hetero-Atom 2 Hetero-Atoms
Links DrugBank   DB08901  
KEGG Drug   D09950  
PDB Ligand   PDBj   RCSB PDB   PDBe
Code 3IK3
TitleAP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance
SouceMus musculus (mouse)
Code 3OXZ
TitleCrystal structure of ABL kinase domain bound with a DFG-out inhibitor AP24534
SouceMus musculus (mouse)
Code 3ZOS
TitleStructure of the DDR1 kinase domain in complex with ponatinib
SouceHOMO SAPIENS (HUMAN)
Code 4C8B
TitleStructure of the kinase domain of human RIPK2 in complex with ponatinib
SouceHOMO SAPIENS (HUMAN)
Code 4QRC
TitleCrystal Structure of the Tyrosine Kinase Domain of FGF Receptor 4 in Complex with Ponatinib
SouceHomo sapiens (human)
Code 4TYJ
TitleStructural analysis of the human Fibroblast Growth Factor Receptor 4 Kinase
SouceHomo sapiens (Human)
Code 4U0I
TitleCrystal structure of KIT in complex with ponatinib
SouceHomo sapiens (Human)
Code 4UXQ
TitleFGFR4 in complex with Ponatinib
SouceHOMO SAPIENS (HUMAN)
Code 4V01
TitleFGFR1 in complex with ponatinib (co-crystallisation).
SouceHOMO SAPIENS (HUMAN)
Code 4V04
TitleFGFR1 in complex with ponatinib.
SouceHOMO SAPIENS (HUMAN)