ID	6R49A	STANDARD;	PRT;	285	AA.
DT	CONVERTED FROM PDB (SEQRES) 6R49
DE	Aurora kinase A
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.210
CC	R-Factor	0.194
FT	#HET	21	 139 	LEU	A	1	501 	ADP	A	S	4
FT	#HET	22	 140 	GLY	A	1	501 	ADP	A	B	5
FT	#HET	23	 141 	LYS	A	1	501 	ADP	A	B	2
FT	#HET	24	 142 	GLY	A	1	501 	ADP	A	B	3
FT	#HET	25	 143 	LYS	A	1	501 	ADP	A	B	1
FT	#HET	26	 144 	PHE	A	1	501 	ADP	A	B	1
FT	#HET	27	 145 	GLY	A	1	501 	ADP	A	B	2
FT	#HET	29	 147 	VAL	A	1	501 	ADP	A	S	9
FT	#HET	42	 160 	ALA	A	1	501 	ADP	A	S	2
FT	#HET	44	 162 	LYS	A	1	501 	ADP	A	S	9
FT	#HET	48	 166 	LYS	A	4	504 	JSB	A	A	8
FT	#HET	51	 169 	LEU	A	4	504 	JSB	A	S	5
FT	#HET	52	 170 	GLU	A	4	504 	JSB	A	S	1
FT	#HET	57	 175 	GLU	A	4	504 	JSB	A	A	7
FT	#HET	60	 178 	LEU	A	4	504 	JSB	A	A	12
FT	#HET	61	 179 	ARG	A	4	504 	JSB	A	A	11
FT	#HET	64	 182 	VAL	A	4	504 	JSB	A	S	1
FT	#HET	76	 194 	LEU	A	1	501 	ADP	A	S	1
FT	#HET	81	 199 	TYR	A	4	504 	JSB	A	S	7
FT	#HET	83	 201 	HIS	A	4	504 	JSB	A	S	28
FT	#HET	88	 206 	VAL	A	4	504 	JSB	A	S	4
FT	#HET	93	 211 	GLU	A	1	501 	ADP	A	B	3
FT	#HET	95	 213 	ALA	A	1	501 	ADP	A	A	7
FT	#HET	99	 217 	THR	A	1	501 	ADP	A	S	2
FT	#HET	142	 260 	GLU	A	1	501 	ADP	A	B	3
FT	#HET	143	 261 	ASN	A	1	501 	ADP	A	S	1
FT	#HET	143	 261 	ASN	A	2	502 	MG	A	S	3
FT	#HET	145	 263 	LEU	A	1	501 	ADP	A	S	4
FT	#HET	156	 274 	ASP	A	1	501 	ADP	A	S	10
FT	#HET	156	 274 	ASP	A	2	502 	MG	A	S	3
FT	#HET	156	 274 	ASP	A	3	503 	MG	A	S	3
FT	DISORDER	1	8
FT	DISORDER	168	172
FT	DISORDER	274	285
CC	SEQUENCE	260 AA (ATOM);
CC	QWALEDFEIG RPLGKGKFGN VYLAREKQSK FILALKVLFK AQLEKAGVEH QLRREVEIQS
CC	HLRHPNILRL YGYFHDATRV YLILEYAPLG TVYRELQKLS KFDEQRTATY ITELANALSY
CC	CHSKRVIHRD IKPENLLLGS AGELKIADFG WSVHAPSSRG TLDYLPPEMI EGRMHDEKVD
CC	LWSLGVLCYE FLVGKPPFEA NTYQETYKRI SRVEFTFPDF VTEGARDLIS RLLKHNPSQR
CC	PMLREVLEHP WITANSSKPS
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GAMESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQ
CC	ATOM   --------QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQ
CC	               ******************************************
CC	SEQRES LEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV
CC	ATOM   LEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV
CC	       **************************************************
CC	SEQRES YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG
CC	ATOM   YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG
CC	       **************************************************
CC	SEQRES ELKIADFGWSVHAPSSRRTXLAGTLDYLPPEMIEGRMHDEKVDLWSLGVL
CC	ATOM   ELKIADFGWSVHAPSSR-----GTLDYLPPEMIEGRMHDEKVDLWSLGVL
CC	       *****************     ****************************
CC	SEQRES CYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNP
CC	ATOM   CYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNP
CC	       **************************************************
CC	SEQRES SQRPMLREVLEHPWITANSSKPSNAQNKESASKQS
CC	ATOM   SQRPMLREVLEHPWITANSSKPS------------
CC	       ***********************            
SQ	SEQUENCE	285 AA;      MW;         CN;
	GAMESKKRQW ALEDFEIGRP LGKGKFGNVY LAREKQSKFI LALKVLFKAQ LEKAGVEHQL
	RREVEIQSHL RHPNILRLYG YFHDATRVYL ILEYAPLGTV YRELQKLSKF DEQRTATYIT
	ELANALSYCH SKRVIHRDIK PENLLLGSAG ELKIADFGWS VHAPSSRRTX LAGTLDYLPP
	EMIEGRMHDE KVDLWSLGVL CYEFLVGKPP FEANTYQETY KRISRVEFTF PDFVTEGARD
	LISRLLKHNP SQRPMLREVL EHPWITANSS KPSNAQNKES ASKQS
//