ID	6MSAA	STANDARD;	PRT;	332	AA.
DT	CONVERTED FROM PDB (SEQRES) 6MSA
DE	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.060
CC	R-Factor	0.200
FT	#SUB	23	 467 	ARG	A	312	 756 	ARG	B	Protein	S	1
FT	#SUB	23	 467 	ARG	A	313	 757 	ASP	B	Protein	S	1
FT	#SUB	23	 467 	ARG	A	316	 760 	SER	B	Protein	S	5
FT	#SUB	27	 471 	GLU	A	316	 760 	SER	B	Protein	S	1
FT	#SUB	27	 471 	GLU	A	320	 764 	LYS	B	Protein	S	3
FT	#SUB	32	 476 	HIS	A	323	 767 	ARG	B	Protein	S	12
FT	#SUB	34	 478 	ASP	A	287	 731 	ASN	B	Protein	S	1
FT	#SUB	37	 481 	PRO	A	287	 731 	ASN	B	Protein	S	1
FT	#SUB	37	 481 	PRO	A	291	 735 	ILE	B	Protein	B	2
FT	#SUB	37	 481 	PRO	A	312	 756 	ARG	B	Protein	B	6
FT	#SUB	37	 481 	PRO	A	315	 759 	LEU	B	Protein	S	3
FT	#SUB	38	 482 	PHE	A	312	 756 	ARG	B	Protein	A	4
FT	#SUB	40	 484 	ASN	A	312	 756 	ARG	B	Protein	S	3
FT	#SUB	41	 485 	MET	A	312	 756 	ARG	B	Protein	S	1
FT	#SUB	237	 681 	LEU	A	283	 727 	LEU	B	Protein	S	1
FT	#SUB	237	 681 	LEU	A	322	 766 	ILE	B	Protein	S	2
FT	#SUB	239	 683 	PRO	A	280	 724 	GLN	B	Protein	S	3
FT	#SUB	239	 683 	PRO	A	284	 728 	GLY	B	Protein	S	2
FT	#SUB	243	 687 	LEU	A	287	 731 	ASN	B	Protein	S	1
FT	#SUB	243	 687 	LEU	A	288	 732 	ALA	B	Protein	S	1
FT	#SUB	317	 761 	GLN	A	277	 721 	GLU	B	Protein	S	3
FT	#SUB	317	 761 	GLN	A	280	 724 	GLN	B	Protein	S	1
FT	#SUB	320	 764 	LYS	A	277	 721 	GLU	B	Protein	S	5
FT	#SUB	324	 768 	GLY	A	268	 712 	PRO	B	Protein	B	2
FT	#SUB	325	 769 	GLU	A	268	 712 	PRO	B	Protein	B	1
FT	#SUB	326	 770 	GLU	A	269	 713 	MET	B	Protein	B	3
FT	#SUB	327	 771 	THR	A	269	 713 	MET	B	Protein	B	1
FT	#SUB	327	 771 	THR	A	277	 721 	GLU	B	Protein	S	2
FT	#SUB	328	 772 	ALA	A	249	 693 	TYR	B	Protein	A	5
FT	#SUB	328	 772 	ALA	A	269	 713 	MET	B	Protein	B	2
FT	#SUB	328	 772 	ALA	A	281	 725 	GLY	B	Protein	S	1
FT	#SUB	329	 773 	THR	A	252	 696 	PHE	B	Protein	S	2
FT	#SUB	329	 773 	THR	A	269	 713 	MET	B	Protein	S	1
FT	#SUB	330	 774 	TRP	A	248	 692 	ILE	B	Protein	S	7
FT	#SUB	330	 774 	TRP	A	252	 696 	PHE	B	Protein	S	2
FT	#SUB	330	 774 	TRP	A	281	 725 	GLY	B	Protein	S	2
FT	#SUB	330	 774 	TRP	A	285	 729 	PHE	B	Protein	S	5
FT	#SUB	330	 774 	TRP	A	288	 732 	ALA	B	Protein	B	1
FT	#HET	85	 529 	HIS	A	1	801 	ZN	A	S	3
FT	#HET	119	 563 	HIS	A	1	801 	ZN	A	S	3
FT	#HET	120	 564 	ASP	A	1	801 	ZN	A	S	3
FT	#HET	120	 564 	ASP	A	2	802 	MG	A	S	3
FT	#HET	148	 592 	GLU	A	2	802 	MG	A	S	1
FT	#HET	191	 635 	LEU	A	3	803 	JY4	A	S	3
FT	#HET	230	 674 	ASP	A	1	801 	ZN	A	S	3
FT	#HET	231	 675 	LEU	A	3	803 	JY4	A	S	2
FT	#HET	248	 692 	ILE	A	3	803 	JY4	A	S	2
FT	#HET	249	 693 	TYR	A	3	803 	JY4	A	S	2
FT	#HET	252	 696 	PHE	A	3	803 	JY4	A	S	2
FT	#HET	269	 713 	MET	A	3	803 	JY4	A	S	1
FT	#HET	282	 726 	GLN	A	3	803 	JY4	A	S	10
FT	#HET	285	 729 	PHE	A	3	803 	JY4	A	S	26
FT	DISORDER	1	2
FT	DISORDER	331	332
CC	SEQUENCE	328 AA (ATOM);
CC	HMSICTSEEW QGLMQFTLPV RLCKEIELFH FDIGPFENMW PGIFVYMVHR SCGTSCFELE
CC	KLCRFIMSVK KNYRRVPYHN WKHAVTVAHC MYAILQNNHT LFTDLERKGL LIACLCHDLD
CC	HRGFSNSYLQ KFDHPLAALY STSTMEQHHF SQTVSILQLE GHNIFSTLSS SEYEQVLEII
CC	RKAIIATDLA LYFGNRKQLE EMYQTGSLNL NNQSHRDRVI GLMMTACDLC SVTKLWPVTK
CC	LTANDIYAEF WAEGDEMKKL GIQPIPMMDR DKKDEVPQGQ LGFYNAVAIP CYTTLTQILP
CC	PTEPLLKACR DNLSQWEKVI RGEETATW
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSHMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMV
CC	ATOM   --HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMV
CC	         ************************************************
CC	SEQRES HRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNN
CC	ATOM   HRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNN
CC	       **************************************************
CC	SEQRES HTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQH
CC	ATOM   HTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQH
CC	       **************************************************
CC	SEQRES HFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQ
CC	ATOM   HFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQ
CC	       **************************************************
CC	SEQRES LEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYA
CC	ATOM   LEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYA
CC	       **************************************************
CC	SEQRES EFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQI
CC	ATOM   EFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQI
CC	       **************************************************
CC	SEQRES LPPTEPLLKACRDNLSQWEKVIRGEETATWIS
CC	ATOM   LPPTEPLLKACRDNLSQWEKVIRGEETATW--
CC	       ******************************  
SQ	SEQUENCE	332 AA;      MW;         CN;
	GSHMSICTSE EWQGLMQFTL PVRLCKEIEL FHFDIGPFEN MWPGIFVYMV HRSCGTSCFE
	LEKLCRFIMS VKKNYRRVPY HNWKHAVTVA HCMYAILQNN HTLFTDLERK GLLIACLCHD
	LDHRGFSNSY LQKFDHPLAA LYSTSTMEQH HFSQTVSILQ LEGHNIFSTL SSSEYEQVLE
	IIRKAIIATD LALYFGNRKQ LEEMYQTGSL NLNNQSHRDR VIGLMMTACD LCSVTKLWPV
	TKLTANDIYA EFWAEGDEMK KLGIQPIPMM DRDKKDEVPQ GQLGFYNAVA IPCYTTLTQI
	LPPTEPLLKA CRDNLSQWEK VIRGEETATW IS
//
ID	6MSAB	STANDARD;	PRT;	332	AA.
DT	CONVERTED FROM PDB (SEQRES) 6MSA
DE	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.060
CC	R-Factor	0.200
FT	#SUB	248	 692 	ILE	B	330	 774 	TRP	A	Protein	A	7
FT	#SUB	249	 693 	TYR	B	328	 772 	ALA	A	Protein	S	5
FT	#SUB	252	 696 	PHE	B	329	 773 	THR	A	Protein	S	2
FT	#SUB	252	 696 	PHE	B	330	 774 	TRP	A	Protein	S	2
FT	#SUB	268	 712 	PRO	B	324	 768 	GLY	A	Protein	S	2
FT	#SUB	268	 712 	PRO	B	325	 769 	GLU	A	Protein	S	1
FT	#SUB	269	 713 	MET	B	326	 770 	GLU	A	Protein	A	3
FT	#SUB	269	 713 	MET	B	327	 771 	THR	A	Protein	B	1
FT	#SUB	269	 713 	MET	B	328	 772 	ALA	A	Protein	S	2
FT	#SUB	269	 713 	MET	B	329	 773 	THR	A	Protein	S	1
FT	#SUB	277	 721 	GLU	B	317	 761 	GLN	A	Protein	S	3
FT	#SUB	277	 721 	GLU	B	320	 764 	LYS	A	Protein	S	5
FT	#SUB	277	 721 	GLU	B	327	 771 	THR	A	Protein	S	2
FT	#SUB	280	 724 	GLN	B	239	 683 	PRO	A	Protein	B	3
FT	#SUB	280	 724 	GLN	B	317	 761 	GLN	A	Protein	S	1
FT	#SUB	281	 725 	GLY	B	328	 772 	ALA	A	Protein	B	1
FT	#SUB	281	 725 	GLY	B	330	 774 	TRP	A	Protein	B	2
FT	#SUB	283	 727 	LEU	B	237	 681 	LEU	A	Protein	S	1
FT	#SUB	284	 728 	GLY	B	239	 683 	PRO	A	Protein	B	2
FT	#SUB	285	 729 	PHE	B	330	 774 	TRP	A	Protein	S	5
FT	#SUB	287	 731 	ASN	B	34	 478 	ASP	A	Protein	S	1
FT	#SUB	287	 731 	ASN	B	37	 481 	PRO	A	Protein	S	1
FT	#SUB	287	 731 	ASN	B	243	 687 	LEU	A	Protein	S	1
FT	#SUB	288	 732 	ALA	B	243	 687 	LEU	A	Protein	S	1
FT	#SUB	288	 732 	ALA	B	330	 774 	TRP	A	Protein	S	1
FT	#SUB	291	 735 	ILE	B	37	 481 	PRO	A	Protein	S	2
FT	#SUB	312	 756 	ARG	B	23	 467 	ARG	A	Protein	B	1
FT	#SUB	312	 756 	ARG	B	37	 481 	PRO	A	Protein	S	6
FT	#SUB	312	 756 	ARG	B	38	 482 	PHE	A	Protein	S	4
FT	#SUB	312	 756 	ARG	B	40	 484 	ASN	A	Protein	S	3
FT	#SUB	312	 756 	ARG	B	41	 485 	MET	A	Protein	S	1
FT	#SUB	313	 757 	ASP	B	23	 467 	ARG	A	Protein	S	1
FT	#SUB	315	 759 	LEU	B	37	 481 	PRO	A	Protein	S	3
FT	#SUB	316	 760 	SER	B	23	 467 	ARG	A	Protein	S	5
FT	#SUB	316	 760 	SER	B	27	 471 	GLU	A	Protein	S	1
FT	#SUB	320	 764 	LYS	B	27	 471 	GLU	A	Protein	S	3
FT	#SUB	322	 766 	ILE	B	237	 681 	LEU	A	Protein	S	2
FT	#SUB	323	 767 	ARG	B	32	 476 	HIS	A	Protein	S	12
FT	#HET	85	 529 	HIS	B	4	801 	ZN	B	S	3
FT	#HET	119	 563 	HIS	B	4	801 	ZN	B	S	3
FT	#HET	119	 563 	HIS	B	5	802 	MG	B	S	1
FT	#HET	120	 564 	ASP	B	4	801 	ZN	B	S	3
FT	#HET	120	 564 	ASP	B	5	802 	MG	B	S	3
FT	#HET	148	 592 	GLU	B	5	802 	MG	B	S	1
FT	#HET	189	 633 	THR	B	5	802 	MG	B	S	1
FT	#HET	230	 674 	ASP	B	4	801 	ZN	B	S	3
FT	DISORDER	1	2
FT	DISORDER	326	332
CC	SEQUENCE	323 AA (ATOM);
CC	HMSICTSEEW QGLMQFTLPV RLCKEIELFH FDIGPFENMW PGIFVYMVHR SCGTSCFELE
CC	KLCRFIMSVK KNYRRVPYHN WKHAVTVAHC MYAILQNNHT LFTDLERKGL LIACLCHDLD
CC	HRGFSNSYLQ KFDHPLAALY STSTMEQHHF SQTVSILQLE GHNIFSTLSS SEYEQVLEII
CC	RKAIIATDLA LYFGNRKQLE EMYQTGSLNL NNQSHRDRVI GLMMTACDLC SVTKLWPVTK
CC	LTANDIYAEF WAEGDEMKKL GIQPIPMMDR DKKDEVPQGQ LGFYNAVAIP CYTTLTQILP
CC	PTEPLLKACR DNLSQWEKVI RGE
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSHMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMV
CC	ATOM   --HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMV
CC	         ************************************************
CC	SEQRES HRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNN
CC	ATOM   HRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNN
CC	       **************************************************
CC	SEQRES HTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQH
CC	ATOM   HTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQH
CC	       **************************************************
CC	SEQRES HFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQ
CC	ATOM   HFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQ
CC	       **************************************************
CC	SEQRES LEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYA
CC	ATOM   LEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYA
CC	       **************************************************
CC	SEQRES EFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQI
CC	ATOM   EFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQI
CC	       **************************************************
CC	SEQRES LPPTEPLLKACRDNLSQWEKVIRGEETATWIS
CC	ATOM   LPPTEPLLKACRDNLSQWEKVIRGE-------
CC	       *************************       
SQ	SEQUENCE	332 AA;      MW;         CN;
	GSHMSICTSE EWQGLMQFTL PVRLCKEIEL FHFDIGPFEN MWPGIFVYMV HRSCGTSCFE
	LEKLCRFIMS VKKNYRRVPY HNWKHAVTVA HCMYAILQNN HTLFTDLERK GLLIACLCHD
	LDHRGFSNSY LQKFDHPLAA LYSTSTMEQH HFSQTVSILQ LEGHNIFSTL SSSEYEQVLE
	IIRKAIIATD LALYFGNRKQ LEEMYQTGSL NLNNQSHRDR VIGLMMTACD LCSVTKLWPV
	TKLTANDIYA EFWAEGDEMK KLGIQPIPMM DRDKKDEVPQ GQLGFYNAVA IPCYTTLTQI
	LPPTEPLLKA CRDNLSQWEK VIRGEETATW IS
//