ID	6JT3A	STANDARD;	PRT;	416	AA.
DT	CONVERTED FROM PDB (SEQRES) 6JT3
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.400
CC	R-Factor	0.189
FT	#HET	34	  11 	GLY	A	5	505 	C83	A	B	7
FT	#HET	35	  12 	GLN	A	5	505 	C83	A	B	5
FT	#HET	36	  13 	GLY	A	5	505 	C83	A	B	10
FT	#HET	37	  14 	TYR	A	5	505 	C83	A	S	1
FT	#HET	53	  30 	LEU	A	5	505 	C83	A	S	2
FT	#HET	55	  32 	ASP	A	5	505 	C83	A	S	11
FT	#HET	57	  34 	GLY	A	4	504 	DMS	A	B	4
FT	#HET	57	  34 	GLY	A	5	505 	C83	A	B	3
FT	#HET	58	  35 	SER	A	4	504 	DMS	A	A	2
FT	#HET	68	  45 	HIS	A	1	501 	IOD	A	S	1
FT	#HET	68	  45 	HIS	A	2	502 	IOD	A	S	1
FT	#HET	73	  50 	ARG	A	3	503 	GOL	A	A	3
FT	#HET	74	  51 	TYR	A	3	503 	GOL	A	A	10
FT	#HET	76	  53 	GLN	A	3	503 	GOL	A	S	6
FT	#HET	94	  71 	TYR	A	4	504 	DMS	A	S	1
FT	#HET	94	  71 	TYR	A	5	505 	C83	A	S	10
FT	#HET	127	 104 	GLU	A	1	501 	IOD	A	B	2
FT	#HET	128	 105 	SER	A	1	501 	IOD	A	A	3
FT	#HET	129	 106 	ASP	A	2	502 	IOD	A	B	1
FT	#HET	130	 107 	LYS	A	2	502 	IOD	A	B	1
FT	#HET	131	 108 	PHE	A	5	505 	C83	A	S	3
FT	#HET	133	 110 	ILE	A	5	505 	C83	A	S	1
FT	#HET	141	 118 	ILE	A	5	505 	C83	A	S	5
FT	#HET	149	 126 	ILE	A	4	504 	DMS	A	S	1
FT	#HET	151	 128 	ARG	A	4	504 	DMS	A	S	2
FT	#HET	221	 198 	TYR	A	4	504 	DMS	A	S	4
FT	#HET	251	 228 	ASP	A	5	505 	C83	A	S	4
FT	#HET	252	 229 	SER	A	5	505 	C83	A	B	2
FT	#HET	253	 230 	GLY	A	5	505 	C83	A	B	17
FT	#HET	254	 231 	THR	A	5	505 	C83	A	A	5
FT	#HET	255	 232 	THR	A	5	505 	C83	A	A	7
FT	#HET	330	 307 	ARG	A	5	505 	C83	A	S	1
FT	#HET	358	 335 	ALA	A	5	505 	C83	A	S	2
FT	DISORDER	1	18
FT	DISORDER	180	190
FT	DISORDER	409	416
CC	SEQUENCE	379 AA (ATOM);
CC	RGSFVEMVDN LRGKSGQGYY VEMTVGSPPQ TLNILVDTGS SNFAVGAAPH PFLHRYYQRQ
CC	LSSTYRDLRK GVYVPYTQGK WEGELGTDLV SIPHGPNVTV RANIAAITES DKFFINGSNW
CC	EGILGLAYAE IARPDDSLEP FFDSLVKQTH VPNLFSLQLC GASVGGSMII GGIDHSLYTG
CC	SLWYTPIRRE WYYEVIIVRV EINGQDLKMD CKEYNYDKSI VDSGTTNLRL PKKVFEAAVK
CC	SIKAASSTEK FPDGFWLGEQ LVCWQAGTTP WNIFPVISLY LMGEVTNQSF RITILPQQYL
CC	RPVEDVATSQ DDCYKFAISQ SSTGTVMGAV IMEGFYVVFD RARKRIGFAV SACHVHDEFR
CC	TAAVEGPFVT LDMEDCGYN
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSHMLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTL
CC	ATOM   ------------------RGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTL
CC	                         ********************************
CC	SEQRES NILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWE
CC	ATOM   NILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWE
CC	       **************************************************
CC	SEQRES GELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA
CC	ATOM   GELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA
CC	       **************************************************
CC	SEQRES RPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG
CC	ATOM   RPDDSLEPFFDSLVKQTHVPNLFSLQLCG-----------ASVGGSMIIG
CC	       *****************************           **********
CC	SEQRES GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIV
CC	ATOM   GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIV
CC	       **************************************************
CC	SEQRES DSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPW
CC	ATOM   DSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPW
CC	       **************************************************
CC	SEQRES NIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQS
CC	ATOM   NIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQS
CC	       **************************************************
CC	SEQRES STGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTL
CC	ATOM   STGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTL
CC	       **************************************************
CC	SEQRES DMEDCGYNIPQTDEST
CC	ATOM   DMEDCGYN--------
CC	       ********        
SQ	SEQUENCE	416 AA;      MW;         CN;
	GSHMLPRETD EEPEEPGRRG SFVEMVDNLR GKSGQGYYVE MTVGSPPQTL NILVDTGSSN
	FAVGAAPHPF LHRYYQRQLS STYRDLRKGV YVPYTQGKWE GELGTDLVSI PHGPNVTVRA
	NIAAITESDK FFINGSNWEG ILGLAYAEIA RPDDSLEPFF DSLVKQTHVP NLFSLQLCGA
	GFPLNQSEVL ASVGGSMIIG GIDHSLYTGS LWYTPIRREW YYEVIIVRVE INGQDLKMDC
	KEYNYDKSIV DSGTTNLRLP KKVFEAAVKS IKAASSTEKF PDGFWLGEQL VCWQAGTTPW
	NIFPVISLYL MGEVTNQSFR ITILPQQYLR PVEDVATSQD DCYKFAISQS STGTVMGAVI
	MEGFYVVFDR ARKRIGFAVS ACHVHDEFRT AAVEGPFVTL DMEDCGYNIP QTDEST
//