ID	6JSZA	STANDARD;	PRT;	386	AA.
DT	CONVERTED FROM PDB (SEQRES) 6JSZ
DE	Beta-secretase 2
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.530
CC	R-Factor	0.226
FT	#SUB	63	  75 	THR	A	56	 216 	ILE	D	Protein	B	2
FT	#SUB	65	  77 	ARG	A	53	 213 	ASP	D	Protein	S	1
FT	#SUB	65	  77 	ARG	A	55	 215 	SER	D	Protein	S	6
FT	#SUB	65	  77 	ARG	A	56	 216 	ILE	D	Protein	S	3
FT	#SUB	67	  79 	LYS	A	30	 190 	SER	D	Protein	S	4
FT	#SUB	69	  81 	PHE	A	30	 190 	SER	D	Protein	S	1
FT	#SUB	86	  98 	GLU	A	30	 190 	SER	D	Protein	S	1
FT	#SUB	86	  98 	GLU	A	32	 192 	ILE	D	Protein	S	3
FT	#SUB	86	  98 	GLU	A	51	 211 	GLY	D	Protein	S	2
FT	#SUB	86	  98 	GLU	A	52	 212 	SER	D	Protein	S	7
FT	#SUB	100	 112 	LEU	A	49	 209 	THR	D	Protein	S	1
FT	#SUB	100	 112 	LEU	A	51	 211 	GLY	D	Protein	S	2
FT	#SUB	100	 112 	LEU	A	56	 216 	ILE	D	Protein	S	1
FT	#SUB	101	 113 	VAL	A	32	 192 	ILE	D	Protein	B	1
FT	#SUB	102	 114 	ASN	A	32	 192 	ILE	D	Protein	A	5
FT	#SUB	135	 147 	SER	A	98	 258 	ALA	D	Protein	B	1
FT	#SUB	135	 147 	SER	A	100	 260 	ARG	D	Protein	A	6
FT	#SUB	136	 148 	SER	A	98	 258 	ALA	D	Protein	B	2
FT	#SUB	138	 150 	GLU	A	97	 257 	SER	D	Protein	S	2
FT	#SUB	138	 150 	GLU	A	98	 258 	ALA	D	Protein	A	9
FT	#SUB	142	 154 	ASP	A	99	 259 	GLY	D	Protein	S	1
FT	#SUB	145	 157 	VAL	A	44	 204 	ARG	D	Protein	A	3
FT	#SUB	146	 158 	THR	A	34	 194 	THR	D	Protein	S	1
FT	#SUB	146	 158 	THR	A	36	 196 	VAL	D	Protein	S	1
FT	#SUB	146	 158 	THR	A	46	 206 	TRP	D	Protein	B	3
FT	#SUB	146	 158 	THR	A	96	 256 	THR	D	Protein	S	1
FT	#SUB	147	 159 	GLN	A	46	 206 	TRP	D	Protein	A	7
FT	#SUB	147	 159 	GLN	A	49	 209 	THR	D	Protein	S	4
FT	#SUB	149	 161 	ASN	A	44	 204 	ARG	D	Protein	S	3
FT	#SUB	149	 161 	ASN	A	45	 205 	GLU	D	Protein	S	2
FT	#SUB	149	 161 	ASN	A	46	 206 	TRP	D	Protein	S	5
FT	#SUB	150	 162 	ILE	A	44	 204 	ARG	D	Protein	B	4
FT	#HET	15	  27 	GLY	A	1	401 	C7O	A	B	6
FT	#HET	16	  28 	ARG	A	1	401 	C7O	A	B	7
FT	#HET	17	  29 	GLY	A	1	401 	C7O	A	B	12
FT	#HET	18	  30 	TYR	A	1	401 	C7O	A	S	2
FT	#HET	34	  46 	LEU	A	1	401 	C7O	A	S	4
FT	#HET	36	  48 	ASP	A	1	401 	C7O	A	S	11
FT	#HET	38	  50 	GLY	A	1	401 	C7O	A	B	3
FT	#HET	39	  51 	SER	A	1	401 	C7O	A	S	2
FT	#HET	67	  79 	LYS	A	2	402 	CL	A	S	1
FT	#HET	73	  85 	VAL	A	1	401 	C7O	A	S	1
FT	#HET	75	  87 	TYR	A	1	401 	C7O	A	S	13
FT	#HET	102	 114 	ASN	A	2	402 	CL	A	S	3
FT	#HET	112	 124 	PHE	A	1	401 	C7O	A	S	2
FT	#HET	119	 131 	TRP	A	1	401 	C7O	A	S	3
FT	#HET	122	 134 	ILE	A	1	401 	C7O	A	S	5
FT	#HET	136	 148 	SER	A	2	402 	CL	A	B	1
FT	#HET	138	 150 	GLU	A	2	402 	CL	A	A	2
FT	#HET	229	 241 	ASP	A	1	401 	C7O	A	S	5
FT	#HET	230	 242 	SER	A	1	401 	C7O	A	B	2
FT	#HET	231	 243 	GLY	A	1	401 	C7O	A	B	17
FT	#HET	232	 244 	THR	A	1	401 	C7O	A	A	5
FT	#HET	233	 245 	THR	A	1	401 	C7O	A	A	10
FT	#HET	335	 347 	ALA	A	1	401 	C7O	A	S	2
FT	DISORDER	13	14
FT	DISORDER	163	171
FT	DISORDER	272	277
FT	DISORDER	311	316
CC	SEQUENCE	363 AA (ATOM);
CC	ANFLAMVDNL QGGRGYYLEM LIGTPPQKLQ ILVDTGSSNF AVAGTPHSYI DTYFDTERSS
CC	TYRSKGFDVT VKYTQGSWTG FVGEDLVTIP KGFNTSFLVN IATIFESENF FLPGIKWNGI
CC	LGLAYATLAK PSSSLETFFD SLVTQANIPN VFSMQMCGAG GGSLVLGGIE PSLYKGDIWY
CC	TPIKEEWYYQ IEILKLEIGG QSLNLDCREY NADKAIVDSG TTLLRLPQKV FDAVVEAVAR
CC	ASLIPEFSDG FWTGSQLACW WSYFPKISIY LRDENSSRSF RITILPQLYI QPMYECYRFG
CC	ISPSTNALVI GATVMEGFYV IFDRAQKRVG FAASPCAEIA GAAVSEISGP FSTEDVASNC
CC	VPA
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES ANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHS
CC	ATOM   ANFLAMVDNLQG--GRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHS
CC	       ************  ************************************
CC	SEQRES YIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFL
CC	ATOM   YIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFL
CC	       **************************************************
CC	SEQRES VNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANI
CC	ATOM   VNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANI
CC	       **************************************************
CC	SEQRES PNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYY
CC	ATOM   PNVFSMQMCGAG---------GGSLVLGGIEPSLYKGDIWYTPIKEEWYY
CC	       ************         *****************************
CC	SEQRES QIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVA
CC	ATOM   QIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVA
CC	       **************************************************
CC	SEQRES RASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRIT
CC	ATOM   RASLIPEFSDGFWTGSQLACW------WSYFPKISIYLRDENSSRSFRIT
CC	       *********************      ***********************
CC	SEQRES ILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQK
CC	ATOM   ILPQLYIQPM------YECYRFGISPSTNALVIGATVMEGFYVIFDRAQK
CC	       **********      **********************************
CC	SEQRES RVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPA
CC	ATOM   RVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPA
CC	       ************************************
SQ	SEQUENCE	386 AA;      MW;         CN;
	ANFLAMVDNL QGDSGRGYYL EMLIGTPPQK LQILVDTGSS NFAVAGTPHS YIDTYFDTER
	SSTYRSKGFD VTVKYTQGSW TGFVGEDLVT IPKGFNTSFL VNIATIFESE NFFLPGIKWN
	GILGLAYATL AKPSSSLETF FDSLVTQANI PNVFSMQMCG AGLPVAGSGT NGGSLVLGGI
	EPSLYKGDIW YTPIKEEWYY QIEILKLEIG GQSLNLDCRE YNADKAIVDS GTTLLRLPQK
	VFDAVVEAVA RASLIPEFSD GFWTGSQLAC WTNSETPWSY FPKISIYLRD ENSSRSFRIT
	ILPQLYIQPM MGAGLNYECY RFGISPSTNA LVIGATVMEG FYVIFDRAQK RVGFAASPCA
	EIAGAAVSEI SGPFSTEDVA SNCVPA
//
ID	6JSZD	STANDARD;	PRT;	111	AA.
DT	CONVERTED FROM PDB (SEQRES) 6JSZ
DE	XAPERONE
OS	syntetic
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.530
CC	R-Factor	0.226
FT	#SUB	30	 190 	SER	D	67	  79 	LYS	A	Protein	B	4
FT	#SUB	30	 190 	SER	D	69	  81 	PHE	A	Protein	S	1
FT	#SUB	30	 190 	SER	D	86	  98 	GLU	A	Protein	B	1
FT	#SUB	32	 192 	ILE	D	86	  98 	GLU	A	Protein	S	3
FT	#SUB	32	 192 	ILE	D	101	 113 	VAL	A	Protein	S	1
FT	#SUB	32	 192 	ILE	D	102	 114 	ASN	A	Protein	S	5
FT	#SUB	34	 194 	THR	D	146	 158 	THR	A	Protein	S	1
FT	#SUB	36	 196 	VAL	D	146	 158 	THR	A	Protein	S	1
FT	#SUB	44	 204 	ARG	D	145	 157 	VAL	A	Protein	S	3
FT	#SUB	44	 204 	ARG	D	149	 161 	ASN	A	Protein	B	3
FT	#SUB	44	 204 	ARG	D	150	 162 	ILE	A	Protein	S	4
FT	#SUB	45	 205 	GLU	D	149	 161 	ASN	A	Protein	B	2
FT	#SUB	46	 206 	TRP	D	146	 158 	THR	A	Protein	S	3
FT	#SUB	46	 206 	TRP	D	147	 159 	GLN	A	Protein	S	7
FT	#SUB	46	 206 	TRP	D	149	 161 	ASN	A	Protein	A	5
FT	#SUB	49	 209 	THR	D	100	 112 	LEU	A	Protein	S	1
FT	#SUB	49	 209 	THR	D	147	 159 	GLN	A	Protein	S	4
FT	#SUB	51	 211 	GLY	D	86	  98 	GLU	A	Protein	B	2
FT	#SUB	51	 211 	GLY	D	100	 112 	LEU	A	Protein	B	2
FT	#SUB	52	 212 	SER	D	86	  98 	GLU	A	Protein	A	7
FT	#SUB	53	 213 	ASP	D	65	  77 	ARG	A	Protein	S	1
FT	#SUB	55	 215 	SER	D	65	  77 	ARG	A	Protein	S	6
FT	#SUB	56	 216 	ILE	D	63	  75 	THR	A	Protein	S	2
FT	#SUB	56	 216 	ILE	D	65	  77 	ARG	A	Protein	S	3
FT	#SUB	56	 216 	ILE	D	100	 112 	LEU	A	Protein	S	1
FT	#SUB	96	 256 	THR	D	146	 158 	THR	A	Protein	S	1
FT	#SUB	97	 257 	SER	D	138	 150 	GLU	A	Protein	B	2
FT	#SUB	98	 258 	ALA	D	135	 147 	SER	A	Protein	S	1
FT	#SUB	98	 258 	ALA	D	136	 148 	SER	A	Protein	S	2
FT	#SUB	98	 258 	ALA	D	138	 150 	GLU	A	Protein	A	9
FT	#SUB	99	 259 	GLY	D	142	 154 	ASP	A	Protein	B	1
FT	#SUB	100	 260 	ARG	D	135	 147 	SER	A	Protein	S	6
FT	#HET	30	 190 	SER	D	2	402 	CL	A	B	1
FT	#HET	31	 191 	ALA	D	2	402 	CL	A	B	1
FT	#HET	32	 192 	ILE	D	2	402 	CL	A	B	1
CC	SEQUENCE	111 AA (ATOM);
CC	VQLQESGGGL VQPGGSLRLS CAASGFTFSS AIMTWVRQAP GKGREWVSTI GSDGSITTYA
CC	DSVKGRFTIS RDNARNTLYL QMNSLKPEDT AVYYCTSAGR RGPGTQVTVS S
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES VQLQESGGGLVQPGGSLRLSCAASGFTFSSAIMTWVRQAPGKGREWVSTI
CC	ATOM   VQLQESGGGLVQPGGSLRLSCAASGFTFSSAIMTWVRQAPGKGREWVSTI
CC	       **************************************************
CC	SEQRES GSDGSITTYADSVKGRFTISRDNARNTLYLQMNSLKPEDTAVYYCTSAGR
CC	ATOM   GSDGSITTYADSVKGRFTISRDNARNTLYLQMNSLKPEDTAVYYCTSAGR
CC	       **************************************************
CC	SEQRES RGPGTQVTVSS
CC	ATOM   RGPGTQVTVSS
CC	       ***********
SQ	SEQUENCE	111 AA;      MW;         CN;
	VQLQESGGGL VQPGGSLRLS CAASGFTFSS AIMTWVRQAP GKGREWVSTI GSDGSITTYA
	DSVKGRFTIS RDNARNTLYL QMNSLKPEDT AVYYCTSAGR RGPGTQVTVS S
//