ID	6JSFA	STANDARD;	PRT;	416	AA.
DT	CONVERTED FROM PDB (SEQRES) 6JSF
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.300
CC	R-Factor	0.186
FT	#HET	19	  20 	ARG	A	2	502 	IOD	A	S	2
FT	#HET	19	  20 	ARG	A	7	507 	IOD	A	B	2
FT	#HET	20	  21 	GLY	A	7	507 	IOD	A	B	2
FT	#HET	34	  35 	GLY	A	10	510 	C7X	A	B	7
FT	#HET	35	  36 	GLN	A	10	510 	C7X	A	B	5
FT	#HET	36	  37 	GLY	A	10	510 	C7X	A	B	10
FT	#HET	37	  38 	TYR	A	10	510 	C7X	A	S	1
FT	#HET	53	  54 	LEU	A	10	510 	C7X	A	S	1
FT	#HET	55	  56 	ASP	A	10	510 	C7X	A	S	10
FT	#HET	57	  58 	GLY	A	10	510 	C7X	A	B	2
FT	#HET	68	  69 	HIS	A	1	501 	IOD	A	S	1
FT	#HET	68	  69 	HIS	A	3	503 	IOD	A	S	1
FT	#HET	94	  95 	TYR	A	10	510 	C7X	A	S	8
FT	#HET	96	  97 	GLN	A	10	510 	C7X	A	S	5
FT	#HET	97	  98 	GLY	A	10	510 	C7X	A	B	5
FT	#HET	119	 120 	ARG	A	4	504 	IOD	A	B	1
FT	#HET	126	 127 	THR	A	1	501 	IOD	A	B	1
FT	#HET	127	 128 	GLU	A	1	501 	IOD	A	B	3
FT	#HET	128	 129 	SER	A	1	501 	IOD	A	A	2
FT	#HET	130	 131 	LYS	A	3	503 	IOD	A	B	1
FT	#HET	130	 131 	LYS	A	10	510 	C7X	A	B	2
FT	#HET	131	 132 	PHE	A	10	510 	C7X	A	S	2
FT	#HET	133	 134 	ILE	A	10	510 	C7X	A	S	1
FT	#HET	138	 139 	TRP	A	10	510 	C7X	A	S	2
FT	#HET	141	 142 	ILE	A	10	510 	C7X	A	S	5
FT	#HET	166	 167 	GLN	A	4	504 	IOD	A	S	1
FT	#HET	204	 205 	HIS	A	7	507 	IOD	A	S	2
FT	#HET	233	 234 	GLY	A	9	509 	DMS	A	B	2
FT	#HET	251	 252 	ASP	A	10	510 	C7X	A	S	4
FT	#HET	252	 253 	SER	A	10	510 	C7X	A	B	2
FT	#HET	253	 254 	GLY	A	10	510 	C7X	A	B	16
FT	#HET	254	 255 	THR	A	10	510 	C7X	A	A	5
FT	#HET	255	 256 	THR	A	10	510 	C7X	A	A	9
FT	#HET	322	 323 	THR	A	9	509 	DMS	A	S	1
FT	#HET	358	 359 	ALA	A	10	510 	C7X	A	S	2
FT	#HET	372	 373 	ARG	A	2	502 	IOD	A	S	3
FT	#HET	390	 391 	THR	A	8	508 	DMS	A	A	3
FT	#HET	392	 393 	ALA	A	8	508 	DMS	A	S	2
FT	#HET	394	 395 	GLU	A	8	508 	DMS	A	S	1
FT	#HET	394	 395 	GLU	A	9	509 	DMS	A	S	1
FT	DISORDER	1	18
FT	DISORDER	181	191
FT	DISORDER	334	340
FT	DISORDER	411	416
CC	SEQUENCE	374 AA (ATOM);
CC	RGSFVEMVDN LRGKSGQGYY VEMTVGSPPQ TLNILVDTGS SNFAVGAAPH PFLHRYYQRQ
CC	LSSTYRDLRK GVYVPYTQGK WEGELGTDLV SIPHGPNVTV RANIAAITES DKFFINGSNW
CC	EGILGLAYAE IARPDDSLEP FFDSLVKQTH VPNLFSLQLC GASVGGSMII GGIDHSLYTG
CC	SLWYTPIRRE WYYEVIIVRV EINGQDLKMD CKEYNYDKSI VDSGTTNLRL PKKVFEAAVK
CC	SIKAASSTEK FPDGFWLGEQ LVCWQAGTTP WNIFPVISLY LMGEVTNQSF RITILPQQYL
CC	RPVEDCYKFA ISQSSTGTVM GAVIMEGFYV VFDRARKRIG FAVSACHVHD EFRTAAVEGP
CC	FVTLDMEDCG YNIP
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSHMLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTL
CC	ATOM   ------------------RGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTL
CC	                         ********************************
CC	SEQRES NILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWE
CC	ATOM   NILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWE
CC	       **************************************************
CC	SEQRES GELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA
CC	ATOM   GELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA
CC	       **************************************************
CC	SEQRES RPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG
CC	ATOM   RPDDSLEPFFDSLVKQTHVPNLFSLQLCGA-----------SVGGSMIIG
CC	       ******************************           *********
CC	SEQRES GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIV
CC	ATOM   GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIV
CC	       **************************************************
CC	SEQRES DSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPW
CC	ATOM   DSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPW
CC	       **************************************************
CC	SEQRES NIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQS
CC	ATOM   NIFPVISLYLMGEVTNQSFRITILPQQYLRPVE-------DCYKFAISQS
CC	       *********************************       **********
CC	SEQRES STGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTL
CC	ATOM   STGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTL
CC	       **************************************************
CC	SEQRES DMEDCGYNIPQTDEST
CC	ATOM   DMEDCGYNIP------
CC	       **********      
SQ	SEQUENCE	416 AA;      MW;         CN;
	GSHMLPRETD EEPEEPGRRG SFVEMVDNLR GKSGQGYYVE MTVGSPPQTL NILVDTGSSN
	FAVGAAPHPF LHRYYQRQLS STYRDLRKGV YVPYTQGKWE GELGTDLVSI PHGPNVTVRA
	NIAAITESDK FFINGSNWEG ILGLAYAEIA RPDDSLEPFF DSLVKQTHVP NLFSLQLCGA
	GFPLNQSEVL ASVGGSMIIG GIDHSLYTGS LWYTPIRREW YYEVIIVRVE INGQDLKMDC
	KEYNYDKSIV DSGTTNLRLP KKVFEAAVKS IKAASSTEKF PDGFWLGEQL VCWQAGTTPW
	NIFPVISLYL MGEVTNQSFR ITILPQQYLR PVEDVATSQD DCYKFAISQS STGTVMGAVI
	MEGFYVVFDR ARKRIGFAVS ACHVHDEFRT AAVEGPFVTL DMEDCGYNIP QTDEST
//