ID	6JSEA	STANDARD;	PRT;	416	AA.
DT	CONVERTED FROM PDB (SEQRES) 6JSE
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.000
CC	R-Factor	0.190
FT	#HET	32	  33 	LYS	A	8	508 	C6R	A	B	1
FT	#HET	34	  35 	GLY	A	8	508 	C6R	A	B	9
FT	#HET	35	  36 	GLN	A	8	508 	C6R	A	B	5
FT	#HET	36	  37 	GLY	A	8	508 	C6R	A	B	11
FT	#HET	37	  38 	TYR	A	8	508 	C6R	A	S	1
FT	#HET	53	  54 	LEU	A	8	508 	C6R	A	S	2
FT	#HET	55	  56 	ASP	A	8	508 	C6R	A	S	11
FT	#HET	57	  58 	GLY	A	8	508 	C6R	A	B	5
FT	#HET	58	  59 	SER	A	8	508 	C6R	A	S	3
FT	#HET	68	  69 	HIS	A	1	501 	IOD	A	S	1
FT	#HET	68	  69 	HIS	A	3	503 	IOD	A	S	1
FT	#HET	92	  93 	VAL	A	8	508 	C6R	A	S	1
FT	#HET	94	  95 	TYR	A	7	507 	DMS	A	A	3
FT	#HET	94	  95 	TYR	A	8	508 	C6R	A	S	12
FT	#HET	95	  96 	THR	A	7	507 	DMS	A	A	5
FT	#HET	96	  97 	GLN	A	7	507 	DMS	A	S	1
FT	#HET	96	  97 	GLN	A	8	508 	C6R	A	S	3
FT	#HET	119	 120 	ARG	A	5	505 	IOD	A	B	1
FT	#HET	126	 127 	THR	A	1	501 	IOD	A	B	1
FT	#HET	127	 128 	GLU	A	1	501 	IOD	A	B	3
FT	#HET	128	 129 	SER	A	1	501 	IOD	A	A	2
FT	#HET	130	 131 	LYS	A	3	503 	IOD	A	B	1
FT	#HET	131	 132 	PHE	A	8	508 	C6R	A	S	2
FT	#HET	133	 134 	ILE	A	8	508 	C6R	A	S	1
FT	#HET	141	 142 	ILE	A	8	508 	C6R	A	S	5
FT	#HET	151	 152 	ARG	A	8	508 	C6R	A	S	1
FT	#HET	157	 158 	GLU	A	5	505 	IOD	A	S	1
FT	#HET	221	 222 	TYR	A	7	507 	DMS	A	S	1
FT	#HET	251	 252 	ASP	A	8	508 	C6R	A	S	4
FT	#HET	252	 253 	SER	A	8	508 	C6R	A	B	2
FT	#HET	253	 254 	GLY	A	8	508 	C6R	A	B	17
FT	#HET	254	 255 	THR	A	8	508 	C6R	A	B	4
FT	#HET	255	 256 	THR	A	8	508 	C6R	A	A	7
FT	#HET	330	 331 	ARG	A	8	508 	C6R	A	S	2
FT	#HET	358	 359 	ALA	A	8	508 	C6R	A	S	2
FT	#HET	372	 373 	ARG	A	2	502 	IOD	A	S	2
FT	DISORDER	1	18
FT	DISORDER	181	190
FT	DISORDER	335	339
FT	DISORDER	410	416
CC	SEQUENCE	376 AA (ATOM);
CC	RGSFVEMVDN LRGKSGQGYY VEMTVGSPPQ TLNILVDTGS SNFAVGAAPH PFLHRYYQRQ
CC	LSSTYRDLRK GVYVPYTQGK WEGELGTDLV SIPHGPNVTV RANIAAITES DKFFINGSNW
CC	EGILGLAYAE IARPDDSLEP FFDSLVKQTH VPNLFSLQLC GAASVGGSMI IGGIDHSLYT
CC	GSLWYTPIRR EWYYEVIIVR VEINGQDLKM DCKEYNYDKS IVDSGTTNLR LPKKVFEAAV
CC	KSIKAASSTE KFPDGFWLGE QLVCWQAGTT PWNIFPVISL YLMGEVTNQS FRITILPQQY
CC	LRPVEDDDCY KFAISQSSTG TVMGAVIMEG FYVVFDRARK RIGFAVSACH VHDEFRTAAV
CC	EGPFVTLDME DCGYNI
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSHMLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTL
CC	ATOM   ------------------RGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTL
CC	                         ********************************
CC	SEQRES NILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWE
CC	ATOM   NILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWE
CC	       **************************************************
CC	SEQRES GELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA
CC	ATOM   GELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA
CC	       **************************************************
CC	SEQRES RPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG
CC	ATOM   RPDDSLEPFFDSLVKQTHVPNLFSLQLCGA----------ASVGGSMIIG
CC	       ******************************          **********
CC	SEQRES GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIV
CC	ATOM   GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIV
CC	       **************************************************
CC	SEQRES DSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPW
CC	ATOM   DSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPW
CC	       **************************************************
CC	SEQRES NIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQS
CC	ATOM   NIFPVISLYLMGEVTNQSFRITILPQQYLRPVED-----DDCYKFAISQS
CC	       **********************************     ***********
CC	SEQRES STGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTL
CC	ATOM   STGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTL
CC	       **************************************************
CC	SEQRES DMEDCGYNIPQTDEST
CC	ATOM   DMEDCGYNI-------
CC	       *********       
SQ	SEQUENCE	416 AA;      MW;         CN;
	GSHMLPRETD EEPEEPGRRG SFVEMVDNLR GKSGQGYYVE MTVGSPPQTL NILVDTGSSN
	FAVGAAPHPF LHRYYQRQLS STYRDLRKGV YVPYTQGKWE GELGTDLVSI PHGPNVTVRA
	NIAAITESDK FFINGSNWEG ILGLAYAEIA RPDDSLEPFF DSLVKQTHVP NLFSLQLCGA
	GFPLNQSEVL ASVGGSMIIG GIDHSLYTGS LWYTPIRREW YYEVIIVRVE INGQDLKMDC
	KEYNYDKSIV DSGTTNLRLP KKVFEAAVKS IKAASSTEKF PDGFWLGEQL VCWQAGTTPW
	NIFPVISLYL MGEVTNQSFR ITILPQQYLR PVEDVATSQD DCYKFAISQS STGTVMGAVI
	MEGFYVVFDR ARKRIGFAVS ACHVHDEFRT AAVEGPFVTL DMEDCGYNIP QTDEST
//