ID	6GLBA	STANDARD;	PRT;	294	AA.
DT	CONVERTED FROM PDB (SEQRES) 6GLB
DE	Tyrosine-protein kinase JAK3
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.000
CC	R-Factor	0.236
FT	#SUB	50	 859 	HIS	A	274	1083 	GLN	B	Protein	S	5
FT	#SUB	50	 859 	HIS	A	275	1084 	ASP	B	Protein	S	4
FT	#SUB	175	 984 	ARG	A	129	 938 	GLU	B	Protein	S	3
FT	#SUB	175	 984 	ARG	A	280	1089 	SER	B	Protein	S	1
FT	#SUB	175	 984 	ARG	A	284	1093 	PRO	B	Protein	S	8
FT	#SUB	175	 984 	ARG	A	287	1096 	ASP	B	Protein	S	1
FT	#SUB	179	 988 	GLN	A	135	 944 	ARG	B	Protein	S	3
FT	#SUB	179	 988 	GLN	A	170	 979 	ASP	B	Protein	S	2
FT	#SUB	179	 988 	GLN	A	197	1006 	ARG	B	Protein	S	9
FT	#SUB	226	1035 	LEU	A	167	 976 	LEU	B	Protein	S	1
FT	#SUB	232	1041 	GLU	A	64	 873 	GLN	B	Protein	S	6
FT	#SUB	232	1041 	GLU	A	67	 876 	LYS	B	Protein	S	1
FT	#SUB	234	1043 	ASP	A	57	 866 	ARG	B	Protein	S	6
FT	#SUB	234	1043 	ASP	A	61	 870 	ARG	B	Protein	S	11
FT	#SUB	234	1043 	ASP	A	64	 873 	GLN	B	Protein	A	4
FT	#SUB	234	1043 	ASP	A	65	 874 	ILE	B	Protein	B	2
FT	#SUB	234	1043 	ASP	A	164	 973 	LEU	B	Protein	B	2
FT	#SUB	235	1044 	VAL	A	64	 873 	GLN	B	Protein	S	1
FT	#SUB	235	1044 	VAL	A	164	 973 	LEU	B	Protein	B	2
FT	#SUB	236	1045 	PRO	A	68	 877 	ALA	B	Protein	S	2
FT	#SUB	236	1045 	PRO	A	134	 943 	ARG	B	Protein	S	2
FT	#SUB	236	1045 	PRO	A	164	 973 	LEU	B	Protein	B	2
FT	#SUB	237	1046 	ALA	A	167	 976 	LEU	B	Protein	S	1
FT	#SUB	238	1047 	LEU	A	133	 942 	SER	B	Protein	S	1
FT	#SUB	238	1047 	LEU	A	134	 943 	ARG	B	Protein	S	4
FT	#SUB	239	1048 	SER	A	68	 877 	ALA	B	Protein	S	3
FT	#SUB	239	1048 	SER	A	134	 943 	ARG	B	Protein	S	2
FT	#HET	14	 823 	LYS	A	3	1203 	EDO	A	S	2
FT	#HET	19	 828 	LEU	A	1	1201 	F48	A	A	7
FT	#HET	20	 829 	GLY	A	1	1201 	F48	A	B	1
FT	#HET	27	 836 	VAL	A	1	1201 	F48	A	S	3
FT	#HET	31	 840 	ARG	A	3	1203 	EDO	A	S	5
FT	#HET	38	 847 	ASN	A	3	1203 	EDO	A	S	2
FT	#HET	44	 853 	ALA	A	1	1201 	F48	A	S	3
FT	#HET	66	 875 	LEU	A	4	1204 	EDO	A	B	1
FT	#HET	67	 876 	LYS	A	4	1204 	EDO	A	B	3
FT	#HET	69	 878 	LEU	A	4	1204 	EDO	A	B	4
FT	#HET	70	 879 	HIS	A	4	1204 	EDO	A	S	6
FT	#HET	75	 884 	VAL	A	1	1201 	F48	A	S	1
FT	#HET	76	 885 	LYS	A	4	1204 	EDO	A	S	2
FT	#HET	77	 886 	TYR	A	4	1204 	EDO	A	A	7
FT	#HET	94	 903 	GLU	A	1	1201 	F48	A	B	5
FT	#HET	95	 904 	TYR	A	1	1201 	F48	A	A	5
FT	#HET	96	 905 	LEU	A	1	1201 	F48	A	B	6
FT	#HET	100	 909 	CYS	A	1	1201 	F48	A	S	2
FT	#HET	144	 953 	ARG	A	1	1201 	F48	A	A	8
FT	#HET	145	 954 	ASN	A	1	1201 	F48	A	S	3
FT	#HET	147	 956 	LEU	A	1	1201 	F48	A	S	12
FT	#HET	157	 966 	ALA	A	1	1201 	F48	A	S	1
FT	#HET	158	 967 	ASP	A	1	1201 	F48	A	S	2
FT	#HET	183	 992 	PHE	A	2	1202 	PHU	A	S	1
FT	#HET	202	1011 	TRP	A	2	1202 	PHU	A	S	3
FT	#HET	221	1030 	PRO	A	2	1202 	PHU	A	B	1
FT	#HET	225	1034 	PHE	A	2	1202 	PHU	A	S	1
FT	#HET	228	1037 	MET	A	2	1202 	PHU	A	S	3
FT	#HET	245	1054 	LEU	A	2	1202 	PHU	A	S	2
FT	#HET	249	1058 	GLN	A	5	1205 	EDO	A	A	3
FT	#HET	250	1059 	ARG	A	2	1202 	PHU	A	A	4
FT	#HET	250	1059 	ARG	A	5	1205 	EDO	A	B	6
FT	#HET	251	1060 	LEU	A	2	1202 	PHU	A	A	17
FT	#HET	269	1078 	TRP	A	2	1202 	PHU	A	S	7
FT	DISORDER	1	3
FT	DISORDER	176	178
CC	SEQUENCE	288 AA (ATOM);
CC	DPTIFEERHL KYISQLGKGN FGSVELCRYD PLGDNTGALV AVKQLQHSGP DQQRDFQREI
CC	QILKALHSDF IVKYRGVSYG PGRQSLRLVM EYLPSGCLRD FLQRHRARLD ASRLLLYSSQ
CC	ICKGMEYLGS RRCVHRALAA RNILVESEAH VKIADFGLAK LLPLDKDYYV VRQSPIFWYA
CC	PESLSDNIFS RQSDVWSFGV VLYELFTYCD KSCSPSAEFL RMMGSERDVP ALSRLLELLE
CC	EGQRLPAPPA CPAEVHELMK LCWAPSPQDR PSFSALGPQL DMLWSGSR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES SMQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQH
CC	ATOM   ---DPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQH
CC	          ***********************************************
CC	SEQRES SGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGC
CC	ATOM   SGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGC
CC	       **************************************************
CC	SEQRES LRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRALAARNILVES
CC	ATOM   LRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRALAARNILVES
CC	       **************************************************
CC	SEQRES EAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSD
CC	ATOM   EAHVKIADFGLAKLLPLDKDYYVVR---QSPIFWYAPESLSDNIFSRQSD
CC	       *************************   **********************
CC	SEQRES VWSFGVVLYELFTYCDKSCSPSAEFLRMMGSERDVPALSRLLELLEEGQR
CC	ATOM   VWSFGVVLYELFTYCDKSCSPSAEFLRMMGSERDVPALSRLLELLEEGQR
CC	       **************************************************
CC	SEQRES LPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSR
CC	ATOM   LPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSR
CC	       ********************************************
SQ	SEQUENCE	294 AA;      MW;         CN;
	SMQDPTIFEE RHLKYISQLG KGNFGSVELC RYDPLGDNTG ALVAVKQLQH SGPDQQRDFQ
	REIQILKALH SDFIVKYRGV SYGPGRQSLR LVMEYLPSGC LRDFLQRHRA RLDASRLLLY
	SSQICKGMEY LGSRRCVHRA LAARNILVES EAHVKIADFG LAKLLPLDKD YYVVREPGQS
	PIFWYAPESL SDNIFSRQSD VWSFGVVLYE LFTYCDKSCS PSAEFLRMMG SERDVPALSR
	LLELLEEGQR LPAPPACPAE VHELMKLCWA PSPQDRPSFS ALGPQLDMLW SGSR
//
ID	6GLBB	STANDARD;	PRT;	294	AA.
DT	CONVERTED FROM PDB (SEQRES) 6GLB
DE	Tyrosine-protein kinase JAK3
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.000
CC	R-Factor	0.236
FT	#SUB	57	 866 	ARG	B	234	1043 	ASP	A	Protein	S	6
FT	#SUB	61	 870 	ARG	B	234	1043 	ASP	A	Protein	A	11
FT	#SUB	64	 873 	GLN	B	232	1041 	GLU	A	Protein	S	6
FT	#SUB	64	 873 	GLN	B	234	1043 	ASP	A	Protein	A	4
FT	#SUB	64	 873 	GLN	B	235	1044 	VAL	A	Protein	S	1
FT	#SUB	65	 874 	ILE	B	234	1043 	ASP	A	Protein	A	2
FT	#SUB	67	 876 	LYS	B	232	1041 	GLU	A	Protein	S	1
FT	#SUB	68	 877 	ALA	B	236	1045 	PRO	A	Protein	S	2
FT	#SUB	68	 877 	ALA	B	239	1048 	SER	A	Protein	A	3
FT	#SUB	129	 938 	GLU	B	175	 984 	ARG	A	Protein	S	3
FT	#SUB	133	 942 	SER	B	238	1047 	LEU	A	Protein	B	1
FT	#SUB	134	 943 	ARG	B	236	1045 	PRO	A	Protein	S	2
FT	#SUB	134	 943 	ARG	B	238	1047 	LEU	A	Protein	S	4
FT	#SUB	134	 943 	ARG	B	239	1048 	SER	A	Protein	S	2
FT	#SUB	135	 944 	ARG	B	179	 988 	GLN	A	Protein	S	3
FT	#SUB	164	 973 	LEU	B	234	1043 	ASP	A	Protein	S	2
FT	#SUB	164	 973 	LEU	B	235	1044 	VAL	A	Protein	S	2
FT	#SUB	164	 973 	LEU	B	236	1045 	PRO	A	Protein	S	2
FT	#SUB	167	 976 	LEU	B	226	1035 	LEU	A	Protein	S	1
FT	#SUB	167	 976 	LEU	B	237	1046 	ALA	A	Protein	S	1
FT	#SUB	170	 979 	ASP	B	179	 988 	GLN	A	Protein	S	2
FT	#SUB	197	1006 	ARG	B	179	 988 	GLN	A	Protein	S	9
FT	#SUB	274	1083 	GLN	B	50	 859 	HIS	A	Protein	B	5
FT	#SUB	275	1084 	ASP	B	50	 859 	HIS	A	Protein	S	4
FT	#SUB	280	1089 	SER	B	175	 984 	ARG	A	Protein	B	1
FT	#SUB	284	1093 	PRO	B	175	 984 	ARG	A	Protein	A	8
FT	#SUB	287	1096 	ASP	B	175	 984 	ARG	A	Protein	S	1
FT	#HET	14	 823 	LYS	B	8	1203 	EDO	B	S	5
FT	#HET	16	 825 	ILE	B	8	1203 	EDO	B	S	2
FT	#HET	19	 828 	LEU	B	6	1201 	F48	B	A	6
FT	#HET	27	 836 	VAL	B	6	1201 	F48	B	S	4
FT	#HET	31	 840 	ARG	B	8	1203 	EDO	B	S	5
FT	#HET	38	 847 	ASN	B	8	1203 	EDO	B	S	3
FT	#HET	44	 853 	ALA	B	6	1201 	F48	B	S	3
FT	#HET	75	 884 	VAL	B	6	1201 	F48	B	S	2
FT	#HET	94	 903 	GLU	B	6	1201 	F48	B	B	5
FT	#HET	95	 904 	TYR	B	6	1201 	F48	B	A	5
FT	#HET	96	 905 	LEU	B	6	1201 	F48	B	B	6
FT	#HET	100	 909 	CYS	B	6	1201 	F48	B	S	4
FT	#HET	144	 953 	ARG	B	6	1201 	F48	B	A	9
FT	#HET	145	 954 	ASN	B	6	1201 	F48	B	S	3
FT	#HET	147	 956 	LEU	B	6	1201 	F48	B	S	14
FT	#HET	157	 966 	ALA	B	6	1201 	F48	B	S	2
FT	#HET	158	 967 	ASP	B	6	1201 	F48	B	A	2
FT	#HET	183	 992 	PHE	B	7	1202 	PHU	B	S	2
FT	#HET	187	 996 	PRO	B	9	1204 	EDO	B	S	4
FT	#HET	202	1011 	TRP	B	7	1202 	PHU	B	S	3
FT	#HET	206	1015 	VAL	B	7	1202 	PHU	B	S	1
FT	#HET	221	1030 	PRO	B	7	1202 	PHU	B	B	1
FT	#HET	228	1037 	MET	B	7	1202 	PHU	B	S	3
FT	#HET	241	1050 	LEU	B	7	1202 	PHU	B	S	3
FT	#HET	245	1054 	LEU	B	7	1202 	PHU	B	S	3
FT	#HET	245	1054 	LEU	B	9	1204 	EDO	B	B	4
FT	#HET	246	1055 	GLU	B	9	1204 	EDO	B	S	1
FT	#HET	250	1059 	ARG	B	7	1202 	PHU	B	A	4
FT	#HET	250	1059 	ARG	B	9	1204 	EDO	B	S	6
FT	#HET	251	1060 	LEU	B	7	1202 	PHU	B	A	12
FT	#HET	269	1078 	TRP	B	7	1202 	PHU	B	S	7
FT	#HET	271	1080 	PRO	B	9	1204 	EDO	B	A	11
FT	DISORDER	1	3
FT	DISORDER	176	178
CC	SEQUENCE	288 AA (ATOM);
CC	DPTIFEERHL KYISQLGKGN FGSVELCRYD PLGDNTGALV AVKQLQHSGP DQQRDFQREI
CC	QILKALHSDF IVKYRGVSYG PGRQSLRLVM EYLPSGCLRD FLQRHRARLD ASRLLLYSSQ
CC	ICKGMEYLGS RRCVHRALAA RNILVESEAH VKIADFGLAK LLPLDKDYYV VRQSPIFWYA
CC	PESLSDNIFS RQSDVWSFGV VLYELFTYCD KSCSPSAEFL RMMGSERDVP ALSRLLELLE
CC	EGQRLPAPPA CPAEVHELMK LCWAPSPQDR PSFSALGPQL DMLWSGSR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES SMQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQH
CC	ATOM   ---DPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQH
CC	          ***********************************************
CC	SEQRES SGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGC
CC	ATOM   SGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGC
CC	       **************************************************
CC	SEQRES LRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRALAARNILVES
CC	ATOM   LRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRALAARNILVES
CC	       **************************************************
CC	SEQRES EAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSD
CC	ATOM   EAHVKIADFGLAKLLPLDKDYYVVR---QSPIFWYAPESLSDNIFSRQSD
CC	       *************************   **********************
CC	SEQRES VWSFGVVLYELFTYCDKSCSPSAEFLRMMGSERDVPALSRLLELLEEGQR
CC	ATOM   VWSFGVVLYELFTYCDKSCSPSAEFLRMMGSERDVPALSRLLELLEEGQR
CC	       **************************************************
CC	SEQRES LPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSR
CC	ATOM   LPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSR
CC	       ********************************************
SQ	SEQUENCE	294 AA;      MW;         CN;
	SMQDPTIFEE RHLKYISQLG KGNFGSVELC RYDPLGDNTG ALVAVKQLQH SGPDQQRDFQ
	REIQILKALH SDFIVKYRGV SYGPGRQSLR LVMEYLPSGC LRDFLQRHRA RLDASRLLLY
	SSQICKGMEY LGSRRCVHRA LAARNILVES EAHVKIADFG LAKLLPLDKD YYVVREPGQS
	PIFWYAPESL SDNIFSRQSD VWSFGVVLYE LFTYCDKSCS PSAEFLRMMG SERDVPALSR
	LLELLEEGQR LPAPPACPAE VHELMKLCWA PSPQDRPSFS ALGPQLDMLW SGSR
//