ID	6GKVA	STANDARD;	PRT;	351	AA.
DT	CONVERTED FROM PDB (SEQRES) 6GKV
DE	Coclaurine N-methyltransferase
OS	Coptis japonica
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.350
CC	R-Factor	0.198
FT	#SUB	43	  49 	THR	A	340	 346 	GLU	B	Protein	A	5
FT	#SUB	44	  50 	TYR	A	231	 237 	LYS	B	Protein	S	9
FT	#SUB	44	  50 	TYR	A	261	 267 	ALA	B	Protein	S	1
FT	#SUB	44	  50 	TYR	A	278	 284 	THR	B	Protein	A	3
FT	#SUB	44	  50 	TYR	A	340	 346 	GLU	B	Protein	A	5
FT	#SUB	44	  50 	TYR	A	343	 349 	MET	B	Protein	S	3
FT	#SUB	45	  51 	GLU	A	278	 284 	THR	B	Protein	A	6
FT	#SUB	48	  54 	ILE	A	276	 282 	HIS	B	Protein	S	1
FT	#SUB	48	  54 	ILE	A	278	 284 	THR	B	Protein	S	1
FT	#SUB	52	  58 	GLN	A	275	 281 	ASN	B	Protein	S	3
FT	#SUB	52	  58 	GLN	A	276	 282 	HIS	B	Protein	S	4
FT	#SUB	56	  62 	HIS	A	274	 280 	VAL	B	Protein	S	2
FT	#SUB	56	  62 	HIS	A	275	 281 	ASN	B	Protein	S	1
FT	#SUB	231	 237 	LYS	A	44	  50 	TYR	B	Protein	A	4
FT	#SUB	265	 271 	LEU	A	266	 272 	TYR	B	Protein	S	5
FT	#SUB	265	 271 	LEU	A	268	 274 	GLN	B	Protein	B	1
FT	#SUB	265	 271 	LEU	A	273	 279 	VAL	B	Protein	B	1
FT	#SUB	266	 272 	TYR	A	265	 271 	LEU	B	Protein	S	5
FT	#SUB	266	 272 	TYR	A	276	 282 	HIS	B	Protein	S	6
FT	#SUB	268	 274 	GLN	A	265	 271 	LEU	B	Protein	S	1
FT	#SUB	268	 274 	GLN	A	268	 274 	GLN	B	Protein	S	5
FT	#SUB	268	 274 	GLN	A	272	 278 	SER	B	Protein	B	2
FT	#SUB	269	 275 	ASP	A	272	 278 	SER	B	Protein	A	6
FT	#SUB	269	 275 	ASP	A	350	 356 	LYS	B	Protein	S	5
FT	#SUB	272	 278 	SER	A	268	 274 	GLN	B	Protein	S	2
FT	#SUB	272	 278 	SER	A	269	 275 	ASP	B	Protein	S	4
FT	#SUB	274	 280 	VAL	A	56	  62 	HIS	B	Protein	B	2
FT	#SUB	275	 281 	ASN	A	52	  58 	GLN	B	Protein	A	7
FT	#SUB	275	 281 	ASN	A	56	  62 	HIS	B	Protein	S	3
FT	#SUB	276	 282 	HIS	A	48	  54 	ILE	B	Protein	B	1
FT	#SUB	276	 282 	HIS	A	52	  58 	GLN	B	Protein	A	7
FT	#SUB	276	 282 	HIS	A	266	 272 	TYR	B	Protein	S	6
FT	#SUB	278	 284 	THR	A	44	  50 	TYR	B	Protein	S	3
FT	#SUB	278	 284 	THR	A	45	  51 	GLU	B	Protein	A	6
FT	#SUB	278	 284 	THR	A	48	  54 	ILE	B	Protein	S	1
FT	#SUB	340	 346 	GLU	A	43	  49 	THR	B	Protein	S	8
FT	#SUB	340	 346 	GLU	A	44	  50 	TYR	B	Protein	S	5
FT	#SUB	343	 349 	MET	A	44	  50 	TYR	B	Protein	S	2
FT	#SUB	350	 356 	LYS	A	269	 275 	ASP	B	Protein	S	2
FT	#HET	67	  73 	VAL	A	1	501 	SAH	A	S	1
FT	#HET	75	  81 	TYR	A	1	501 	SAH	A	S	13
FT	#HET	75	  81 	TYR	A	2	502 	F2W	A	S	2
FT	#HET	92	  98 	GLY	A	1	501 	SAH	A	B	2
FT	#HET	93	  99 	SER	A	1	501 	SAH	A	S	4
FT	#HET	131	 137 	GLY	A	1	501 	SAH	A	B	11
FT	#HET	132	 138 	CYS	A	1	501 	SAH	A	B	3
FT	#HET	133	 139 	GLY	A	1	501 	SAH	A	B	6
FT	#HET	155	 161 	ASN	A	1	501 	SAH	A	A	18
FT	#HET	159	 165 	GLN	A	1	501 	SAH	A	S	8
FT	#HET	180	 186 	ALA	A	1	501 	SAH	A	B	1
FT	#HET	181	 187 	ASP	A	1	501 	SAH	A	S	3
FT	#HET	182	 188 	ILE	A	1	501 	SAH	A	A	8
FT	#HET	183	 189 	THR	A	1	501 	SAH	A	S	1
FT	#HET	197	 203 	ILE	A	1	501 	SAH	A	A	5
FT	#HET	198	 204 	GLU	A	1	501 	SAH	A	B	3
FT	#HET	198	 204 	GLU	A	2	502 	F2W	A	A	10
FT	#HET	199	 205 	LEU	A	1	501 	SAH	A	S	8
FT	#HET	202	 208 	HIS	A	1	501 	SAH	A	S	1
FT	#HET	202	 208 	HIS	A	2	502 	F2W	A	S	1
FT	#HET	203	 209 	MET	A	1	501 	SAH	A	S	4
FT	#HET	251	 257 	PHE	A	2	502 	F2W	A	S	9
FT	#HET	258	 264 	ILE	A	2	502 	F2W	A	S	1
FT	#HET	284	 290 	PHE	A	2	502 	F2W	A	S	3
FT	#HET	288	 294 	ASN	A	2	502 	F2W	A	S	1
FT	#HET	326	 332 	PHE	A	2	502 	F2W	A	A	3
FT	#HET	330	 336 	GLY	A	2	502 	F2W	A	B	3
FT	#HET	333	 339 	MET	A	2	502 	F2W	A	S	2
FT	#HET	334	 340 	PHE	A	2	502 	F2W	A	S	1
CC	SEQUENCE	351 AA (ATOM);
CC	QTKKAAIVEL LKQLELGLVP YDDIKQLIRR ELARRLQWGY KPTYEEQIAE IQNLTHSLRQ
CC	MKIATEVETL DSQLYEIPIE FLKIMNGSNL KGSCCYFKED STTLDEAEIA MLDLYCERAQ
CC	IQDGQSVLDL GCGQGALTLH VAQKYKNCRV TAVTNSVSQK EYIEEESRRR NLLNVEVKLA
CC	DITTHEMAET YDRILVIELF EHMKNYELLL RKISEWISKD GLLFLEHICH KTFAYHYEPL
CC	DDDDWFTEYV FPAGTMIIPS ASFFLYFQDD VSVVNHWTLS GKHFSRTNEE WLKRLDANLD
CC	VIKPMFETLM GNEEEAVKLI NYWRGFCLSG MEMFGYNNGE EWMASHVLFK K
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES QTKKAAIVELLKQLELGLVPYDDIKQLIRRELARRLQWGYKPTYEEQIAE
CC	ATOM   QTKKAAIVELLKQLELGLVPYDDIKQLIRRELARRLQWGYKPTYEEQIAE
CC	       **************************************************
CC	SEQRES IQNLTHSLRQMKIATEVETLDSQLYEIPIEFLKIMNGSNLKGSCCYFKED
CC	ATOM   IQNLTHSLRQMKIATEVETLDSQLYEIPIEFLKIMNGSNLKGSCCYFKED
CC	       **************************************************
CC	SEQRES STTLDEAEIAMLDLYCERAQIQDGQSVLDLGCGQGALTLHVAQKYKNCRV
CC	ATOM   STTLDEAEIAMLDLYCERAQIQDGQSVLDLGCGQGALTLHVAQKYKNCRV
CC	       **************************************************
CC	SEQRES TAVTNSVSQKEYIEEESRRRNLLNVEVKLADITTHEMAETYDRILVIELF
CC	ATOM   TAVTNSVSQKEYIEEESRRRNLLNVEVKLADITTHEMAETYDRILVIELF
CC	       **************************************************
CC	SEQRES EHMKNYELLLRKISEWISKDGLLFLEHICHKTFAYHYEPLDDDDWFTEYV
CC	ATOM   EHMKNYELLLRKISEWISKDGLLFLEHICHKTFAYHYEPLDDDDWFTEYV
CC	       **************************************************
CC	SEQRES FPAGTMIIPSASFFLYFQDDVSVVNHWTLSGKHFSRTNEEWLKRLDANLD
CC	ATOM   FPAGTMIIPSASFFLYFQDDVSVVNHWTLSGKHFSRTNEEWLKRLDANLD
CC	       **************************************************
CC	SEQRES VIKPMFETLMGNEEEAVKLINYWRGFCLSGMEMFGYNNGEEWMASHVLFK
CC	ATOM   VIKPMFETLMGNEEEAVKLINYWRGFCLSGMEMFGYNNGEEWMASHVLFK
CC	       **************************************************
CC	SEQRES K
CC	ATOM   K
CC	       *
SQ	SEQUENCE	351 AA;      MW;         CN;
	QTKKAAIVEL LKQLELGLVP YDDIKQLIRR ELARRLQWGY KPTYEEQIAE IQNLTHSLRQ
	MKIATEVETL DSQLYEIPIE FLKIMNGSNL KGSCCYFKED STTLDEAEIA MLDLYCERAQ
	IQDGQSVLDL GCGQGALTLH VAQKYKNCRV TAVTNSVSQK EYIEEESRRR NLLNVEVKLA
	DITTHEMAET YDRILVIELF EHMKNYELLL RKISEWISKD GLLFLEHICH KTFAYHYEPL
	DDDDWFTEYV FPAGTMIIPS ASFFLYFQDD VSVVNHWTLS GKHFSRTNEE WLKRLDANLD
	VIKPMFETLM GNEEEAVKLI NYWRGFCLSG MEMFGYNNGE EWMASHVLFK K
//
ID	6GKVB	STANDARD;	PRT;	351	AA.
DT	CONVERTED FROM PDB (SEQRES) 6GKV
DE	Coclaurine N-methyltransferase
OS	Coptis japonica
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.350
CC	R-Factor	0.198
FT	#SUB	43	  49 	THR	B	340	 346 	GLU	A	Protein	A	8
FT	#SUB	44	  50 	TYR	B	231	 237 	LYS	A	Protein	S	4
FT	#SUB	44	  50 	TYR	B	278	 284 	THR	A	Protein	A	3
FT	#SUB	44	  50 	TYR	B	340	 346 	GLU	A	Protein	A	5
FT	#SUB	44	  50 	TYR	B	343	 349 	MET	A	Protein	S	2
FT	#SUB	45	  51 	GLU	B	278	 284 	THR	A	Protein	A	6
FT	#SUB	48	  54 	ILE	B	276	 282 	HIS	A	Protein	S	1
FT	#SUB	48	  54 	ILE	B	278	 284 	THR	A	Protein	S	1
FT	#SUB	52	  58 	GLN	B	275	 281 	ASN	A	Protein	S	7
FT	#SUB	52	  58 	GLN	B	276	 282 	HIS	A	Protein	S	7
FT	#SUB	56	  62 	HIS	B	274	 280 	VAL	A	Protein	S	2
FT	#SUB	56	  62 	HIS	B	275	 281 	ASN	A	Protein	S	3
FT	#SUB	231	 237 	LYS	B	44	  50 	TYR	A	Protein	A	9
FT	#SUB	261	 267 	ALA	B	44	  50 	TYR	A	Protein	S	1
FT	#SUB	265	 271 	LEU	B	266	 272 	TYR	A	Protein	S	5
FT	#SUB	265	 271 	LEU	B	268	 274 	GLN	A	Protein	B	1
FT	#SUB	266	 272 	TYR	B	265	 271 	LEU	A	Protein	S	5
FT	#SUB	266	 272 	TYR	B	276	 282 	HIS	A	Protein	S	6
FT	#SUB	268	 274 	GLN	B	265	 271 	LEU	A	Protein	S	1
FT	#SUB	268	 274 	GLN	B	268	 274 	GLN	A	Protein	S	5
FT	#SUB	268	 274 	GLN	B	272	 278 	SER	A	Protein	B	2
FT	#SUB	269	 275 	ASP	B	272	 278 	SER	A	Protein	A	4
FT	#SUB	269	 275 	ASP	B	350	 356 	LYS	A	Protein	S	2
FT	#SUB	272	 278 	SER	B	268	 274 	GLN	A	Protein	S	2
FT	#SUB	272	 278 	SER	B	269	 275 	ASP	A	Protein	S	6
FT	#SUB	273	 279 	VAL	B	265	 271 	LEU	A	Protein	S	1
FT	#SUB	274	 280 	VAL	B	56	  62 	HIS	A	Protein	B	2
FT	#SUB	275	 281 	ASN	B	52	  58 	GLN	A	Protein	A	3
FT	#SUB	275	 281 	ASN	B	56	  62 	HIS	A	Protein	S	1
FT	#SUB	276	 282 	HIS	B	48	  54 	ILE	A	Protein	B	1
FT	#SUB	276	 282 	HIS	B	52	  58 	GLN	A	Protein	B	4
FT	#SUB	276	 282 	HIS	B	266	 272 	TYR	A	Protein	S	6
FT	#SUB	278	 284 	THR	B	44	  50 	TYR	A	Protein	S	3
FT	#SUB	278	 284 	THR	B	45	  51 	GLU	A	Protein	A	6
FT	#SUB	278	 284 	THR	B	48	  54 	ILE	A	Protein	S	1
FT	#SUB	340	 346 	GLU	B	43	  49 	THR	A	Protein	S	5
FT	#SUB	340	 346 	GLU	B	44	  50 	TYR	A	Protein	S	5
FT	#SUB	343	 349 	MET	B	44	  50 	TYR	A	Protein	S	3
FT	#SUB	350	 356 	LYS	B	269	 275 	ASP	A	Protein	S	5
FT	#HET	71	  77 	ASP	B	4	402 	SAH	B	S	2
FT	#HET	75	  81 	TYR	B	4	402 	SAH	B	S	10
FT	#HET	91	  97 	LYS	B	4	402 	SAH	B	B	2
FT	#HET	92	  98 	GLY	B	3	401 	F2W	B	B	1
FT	#HET	92	  98 	GLY	B	4	402 	SAH	B	B	3
FT	#HET	93	  99 	SER	B	4	402 	SAH	B	S	4
FT	#HET	131	 137 	GLY	B	4	402 	SAH	B	B	11
FT	#HET	132	 138 	CYS	B	4	402 	SAH	B	B	4
FT	#HET	133	 139 	GLY	B	4	402 	SAH	B	B	5
FT	#HET	154	 160 	THR	B	4	402 	SAH	B	A	3
FT	#HET	155	 161 	ASN	B	4	402 	SAH	B	A	22
FT	#HET	159	 165 	GLN	B	4	402 	SAH	B	S	9
FT	#HET	180	 186 	ALA	B	4	402 	SAH	B	B	2
FT	#HET	181	 187 	ASP	B	4	402 	SAH	B	A	6
FT	#HET	182	 188 	ILE	B	4	402 	SAH	B	A	6
FT	#HET	183	 189 	THR	B	4	402 	SAH	B	S	1
FT	#HET	197	 203 	ILE	B	4	402 	SAH	B	A	4
FT	#HET	198	 204 	GLU	B	3	401 	F2W	B	A	8
FT	#HET	198	 204 	GLU	B	4	402 	SAH	B	B	3
FT	#HET	199	 205 	LEU	B	4	402 	SAH	B	S	4
FT	#HET	202	 208 	HIS	B	3	401 	F2W	B	S	1
FT	#HET	251	 257 	PHE	B	3	401 	F2W	B	S	10
FT	#HET	256	 262 	MET	B	3	401 	F2W	B	S	4
FT	#HET	258	 264 	ILE	B	3	401 	F2W	B	S	1
FT	#HET	284	 290 	PHE	B	3	401 	F2W	B	S	5
FT	#HET	288	 294 	ASN	B	3	401 	F2W	B	S	3
FT	#HET	326	 332 	PHE	B	3	401 	F2W	B	A	2
FT	#HET	330	 336 	GLY	B	3	401 	F2W	B	B	4
FT	#HET	334	 340 	PHE	B	3	401 	F2W	B	S	1
FT	DISORDER	1	4
CC	SEQUENCE	347 AA (ATOM);
CC	AAIVELLKQL ELGLVPYDDI KQLIRRELAR RLQWGYKPTY EEQIAEIQNL THSLRQMKIA
CC	TEVETLDSQL YEIPIEFLKI MNGSNLKGSC CYFKEDSTTL DEAEIAMLDL YCERAQIQDG
CC	QSVLDLGCGQ GALTLHVAQK YKNCRVTAVT NSVSQKEYIE EESRRRNLLN VEVKLADITT
CC	HEMAETYDRI LVIELFEHMK NYELLLRKIS EWISKDGLLF LEHICHKTFA YHYEPLDDDD
CC	WFTEYVFPAG TMIIPSASFF LYFQDDVSVV NHWTLSGKHF SRTNEEWLKR LDANLDVIKP
CC	MFETLMGNEE EAVKLINYWR GFCLSGMEMF GYNNGEEWMA SHVLFKK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES QTKKAAIVELLKQLELGLVPYDDIKQLIRRELARRLQWGYKPTYEEQIAE
CC	ATOM   ----AAIVELLKQLELGLVPYDDIKQLIRRELARRLQWGYKPTYEEQIAE
CC	           **********************************************
CC	SEQRES IQNLTHSLRQMKIATEVETLDSQLYEIPIEFLKIMNGSNLKGSCCYFKED
CC	ATOM   IQNLTHSLRQMKIATEVETLDSQLYEIPIEFLKIMNGSNLKGSCCYFKED
CC	       **************************************************
CC	SEQRES STTLDEAEIAMLDLYCERAQIQDGQSVLDLGCGQGALTLHVAQKYKNCRV
CC	ATOM   STTLDEAEIAMLDLYCERAQIQDGQSVLDLGCGQGALTLHVAQKYKNCRV
CC	       **************************************************
CC	SEQRES TAVTNSVSQKEYIEEESRRRNLLNVEVKLADITTHEMAETYDRILVIELF
CC	ATOM   TAVTNSVSQKEYIEEESRRRNLLNVEVKLADITTHEMAETYDRILVIELF
CC	       **************************************************
CC	SEQRES EHMKNYELLLRKISEWISKDGLLFLEHICHKTFAYHYEPLDDDDWFTEYV
CC	ATOM   EHMKNYELLLRKISEWISKDGLLFLEHICHKTFAYHYEPLDDDDWFTEYV
CC	       **************************************************
CC	SEQRES FPAGTMIIPSASFFLYFQDDVSVVNHWTLSGKHFSRTNEEWLKRLDANLD
CC	ATOM   FPAGTMIIPSASFFLYFQDDVSVVNHWTLSGKHFSRTNEEWLKRLDANLD
CC	       **************************************************
CC	SEQRES VIKPMFETLMGNEEEAVKLINYWRGFCLSGMEMFGYNNGEEWMASHVLFK
CC	ATOM   VIKPMFETLMGNEEEAVKLINYWRGFCLSGMEMFGYNNGEEWMASHVLFK
CC	       **************************************************
CC	SEQRES K
CC	ATOM   K
CC	       *
SQ	SEQUENCE	351 AA;      MW;         CN;
	QTKKAAIVEL LKQLELGLVP YDDIKQLIRR ELARRLQWGY KPTYEEQIAE IQNLTHSLRQ
	MKIATEVETL DSQLYEIPIE FLKIMNGSNL KGSCCYFKED STTLDEAEIA MLDLYCERAQ
	IQDGQSVLDL GCGQGALTLH VAQKYKNCRV TAVTNSVSQK EYIEEESRRR NLLNVEVKLA
	DITTHEMAET YDRILVIELF EHMKNYELLL RKISEWISKD GLLFLEHICH KTFAYHYEPL
	DDDDWFTEYV FPAGTMIIPS ASFFLYFQDD VSVVNHWTLS GKHFSRTNEE WLKRLDANLD
	VIKPMFETLM GNEEEAVKLI NYWRGFCLSG MEMFGYNNGE EWMASHVLFK K
//