ID	6EZFA	STANDARD;	PRT;	353	AA.
DT	CONVERTED FROM PDB (SEQRES) 6EZF
DE	cGMP-dependent 3',5'-cyclic phosphodiesterase
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.500
CC	R-Factor	0.152
FT	#HET	32	 606 	THR	A	6	1006 	SO4	A	S	1
FT	#HET	82	 656 	HIS	A	7	1007 	NA	A	S	3
FT	#HET	86	 660 	HIS	A	2	1002 	ZN	A	S	3
FT	#HET	122	 696 	HIS	A	2	1002 	ZN	A	S	3
FT	#HET	123	 697 	ASP	A	1	1001 	MG	A	S	3
FT	#HET	123	 697 	ASP	A	2	1002 	ZN	A	S	3
FT	#HET	133	 707 	PHE	A	3	1003 	C6Z	A	S	1
FT	#HET	140	 714 	VAL	A	3	1003 	C6Z	A	S	1
FT	#HET	143	 717 	ALA	A	3	1003 	C6Z	A	A	3
FT	#HET	144	 718 	LEU	A	3	1003 	C6Z	A	A	4
FT	#HET	145	 719 	TYR	A	4	1004 	GOL	A	S	4
FT	#HET	196	 770 	LEU	A	3	1003 	C6Z	A	S	1
FT	#HET	200	 774 	LEU	A	4	1004 	GOL	A	S	4
FT	#HET	203	 777 	PHE	A	4	1004 	GOL	A	S	14
FT	#HET	234	 808 	ASP	A	2	1002 	ZN	A	S	3
FT	#HET	238	 812 	GLN	A	3	1003 	C6Z	A	S	3
FT	#HET	240	 814 	LYS	A	6	1006 	SO4	A	S	1
FT	#HET	241	 815 	GLY	A	6	1006 	SO4	A	B	10
FT	#HET	243	 817 	LYS	A	6	1006 	SO4	A	A	4
FT	#HET	244	 818 	THR	A	6	1006 	SO4	A	A	6
FT	#HET	252	 826 	ILE	A	3	1003 	C6Z	A	S	6
FT	#HET	253	 827 	TYR	A	3	1003 	C6Z	A	S	1
FT	#HET	256	 830 	PHE	A	3	1003 	C6Z	A	S	5
FT	#HET	273	 847 	MET	A	3	1003 	C6Z	A	S	1
FT	#HET	285	 859 	GLN	A	3	1003 	C6Z	A	S	4
FT	#HET	288	 862 	PHE	A	3	1003 	C6Z	A	S	19
FT	#HET	290	 864 	GLU	A	5	1005 	GOL	A	A	5
FT	#HET	291	 865 	HIS	A	4	1004 	GOL	A	B	9
FT	#HET	291	 865 	HIS	A	5	1005 	GOL	A	S	2
FT	#HET	295	 869 	PRO	A	4	1004 	GOL	A	S	4
FT	DISORDER	1	5
FT	DISORDER	348	353
CC	SEQUENCE	342 AA (ATOM);
CC	DEYTKLLHDG IQPVAAIDSN FASFTYTPRS LPEDDTSMAI LSMLQDMNFI NNYKIDCPTL
CC	ARFCLMVKKG YRDPPYHNWM HAFSVSHFCY LLYKNLELTN YLEDIEIFAL FISCMCHDLD
CC	HRGTNNSFQV ASKSVLAALY SSEGSVMERH HFAQAIAILN THGCNIFDHF SRKDYQRMLD
CC	LMRDIILATD LAHHLRIFKD LQKMAEVGYD RNNKQHHRLL LCLLMTSCDL SDQTKGWKTT
CC	RKIAELIYKE FFSQGDLEKA MGNRPMEMMD REKAYIPELQ ISFMEHIAMP IYKLLQDLFP
CC	KAAELYERVA SNREHWTKVS HKFTIRGLPS NNSLDFLDEE LE
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MHASDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQ
CC	ATOM   -----DEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQ
CC	            *********************************************
CC	SEQRES DMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKN
CC	ATOM   DMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKN
CC	       **************************************************
CC	SEQRES LELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGS
CC	ATOM   LELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGS
CC	       **************************************************
CC	SEQRES VMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHL
CC	ATOM   VMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHL
CC	       **************************************************
CC	SEQRES RIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAE
CC	ATOM   RIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAE
CC	       **************************************************
CC	SEQRES LIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLL
CC	ATOM   LIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLL
CC	       **************************************************
CC	SEQRES QDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEELEHHH
CC	ATOM   QDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEELE---
CC	       ***********************************************   
CC	SEQRES HHH
CC	ATOM   ---
CC	          
SQ	SEQUENCE	353 AA;      MW;         CN;
	MHASDDEYTK LLHDGIQPVA AIDSNFASFT YTPRSLPEDD TSMAILSMLQ DMNFINNYKI
	DCPTLARFCL MVKKGYRDPP YHNWMHAFSV SHFCYLLYKN LELTNYLEDI EIFALFISCM
	CHDLDHRGTN NSFQVASKSV LAALYSSEGS VMERHHFAQA IAILNTHGCN IFDHFSRKDY
	QRMLDLMRDI ILATDLAHHL RIFKDLQKMA EVGYDRNNKQ HHRLLLCLLM TSCDLSDQTK
	GWKTTRKIAE LIYKEFFSQG DLEKAMGNRP MEMMDREKAY IPELQISFME HIAMPIYKLL
	QDLFPKAAEL YERVASNREH WTKVSHKFTI RGLPSNNSLD FLDEELEHHH HHH
//