ID	6DAJA	STANDARD;	PRT;	487	AA.
DT	CONVERTED FROM PDB (SEQRES) 6DAJ
DE	Cytochrome P450 3A4
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.450
CC	R-Factor	0.207
FT	#HET	35	  55 	LYS	A	3	603 	GOL	A	B	2
FT	#HET	36	  56 	GLY	A	3	603 	GOL	A	B	8
FT	#HET	37	  57 	PHE	A	3	603 	GOL	A	A	8
FT	#HET	38	  58 	CYS	A	3	603 	GOL	A	A	9
FT	#HET	39	  59 	MET	A	3	603 	GOL	A	A	2
FT	#HET	85	 105 	ARG	A	1	601 	HEM	A	S	12
FT	#HET	88	 108 	PHE	A	2	602 	FZV	A	S	6
FT	#HET	98	 118 	ILE	A	1	601 	HEM	A	A	4
FT	#HET	99	 119 	SER	A	1	601 	HEM	A	A	2
FT	#HET	99	 119 	SER	A	2	602 	FZV	A	S	4
FT	#HET	104	 124 	GLU	A	4	604 	GLN	A	S	2
FT	#HET	106	 126 	TRP	A	1	601 	HEM	A	S	3
FT	#HET	107	 127 	LYS	A	4	604 	GLN	A	S	3
FT	#HET	110	 130 	ARG	A	1	601 	HEM	A	S	5
FT	#HET	117	 137 	PHE	A	1	601 	HEM	A	S	2
FT	#HET	221	 241 	PHE	A	2	602 	FZV	A	S	2
FT	#HET	281	 301 	ILE	A	2	602 	FZV	A	S	2
FT	#HET	282	 302 	PHE	A	1	601 	HEM	A	S	3
FT	#HET	284	 304 	PHE	A	2	602 	FZV	A	S	13
FT	#HET	285	 305 	ALA	A	1	601 	HEM	A	S	5
FT	#HET	285	 305 	ALA	A	2	602 	FZV	A	A	7
FT	#HET	286	 306 	GLY	A	1	601 	HEM	A	B	1
FT	#HET	289	 309 	THR	A	1	601 	HEM	A	S	2
FT	#HET	289	 309 	THR	A	2	602 	FZV	A	S	2
FT	#HET	293	 313 	VAL	A	1	601 	HEM	A	S	1
FT	#HET	349	 369 	ILE	A	1	601 	HEM	A	S	3
FT	#HET	350	 370 	ALA	A	1	601 	HEM	A	S	1
FT	#HET	351	 371 	MET	A	3	603 	GOL	A	S	5
FT	#HET	353	 373 	LEU	A	1	601 	HEM	A	S	5
FT	#HET	355	 375 	ARG	A	1	601 	HEM	A	S	8
FT	#HET	414	 434 	PRO	A	1	601 	HEM	A	B	4
FT	#HET	415	 435 	PHE	A	1	601 	HEM	A	A	13
FT	#HET	416	 436 	GLY	A	1	601 	HEM	A	B	5
FT	#HET	417	 437 	SER	A	1	601 	HEM	A	B	2
FT	#HET	420	 440 	ARG	A	1	601 	HEM	A	A	12
FT	#HET	421	 441 	ASN	A	1	601 	HEM	A	B	6
FT	#HET	422	 442 	CYS	A	1	601 	HEM	A	A	26
FT	#HET	423	 443 	ILE	A	1	601 	HEM	A	S	3
FT	#HET	424	 444 	GLY	A	1	601 	HEM	A	B	4
FT	#HET	427	 447 	PHE	A	1	601 	HEM	A	S	1
FT	#HET	428	 448 	ALA	A	1	601 	HEM	A	S	3
FT	#HET	432	 452 	MET	A	1	601 	HEM	A	S	2
FT	#HET	457	 477 	LEU	A	3	603 	GOL	A	S	1
FT	#HET	458	 478 	SER	A	3	603 	GOL	A	B	2
FT	#HET	460	 480 	GLY	A	3	603 	GOL	A	B	3
FT	#HET	463	 483 	LEU	A	3	603 	GOL	A	S	1
FT	DISORDER	1	7
FT	DISORDER	191	197
FT	DISORDER	242	248
FT	DISORDER	261	265
FT	DISORDER	477	487
CC	SEQUENCE	450 AA (ATOM);
CC	HSHGLFKKLG IPGPTPLPFL GNILSYHKGF CMFDMECHKK YGKVWGFYDG QQPVLAITDP
CC	DMIKTVLVKE CYSVFTNRRP FGPVGFMKSA ISIAEDEEWK RLRSLLSPTF TSGKLKEMVP
CC	IIAQYGDVLV RNLRREAETG KPVTLKDVFG AYSMDVITST SFGVNIDSLN NPQDPFVENT
CC	KKLPFFLSIT VFPFLIPILE VLNICVFPRE VTNFLRKSVK RMKESRLVDF LQLMIDSQNS
CC	HKALSDLELV AQSIIFIFAG YETTSSVLSF IMYELATHPD VQQKLQEEID AVLPNKAPPT
CC	YDTVLQMEYL DMVVNETLRL FPIAMRLERV CKKDVEINGM FIPKGVVVMI PSYALHRDPK
CC	YWTEPEKFLP ERFSKKNKDN IDPYIYTPFG SGPRNCIGMR FALMNMKLAL IRVLQNFSFK
CC	PCKETQIPLK LSLGGLLQPE KPVVLKVESR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGK
CC	ATOM   -------HSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGK
CC	              *******************************************
CC	SEQRES VWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISI
CC	ATOM   VWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISI
CC	       **************************************************
CC	SEQRES AEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPV
CC	ATOM   AEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPV
CC	       **************************************************
CC	SEQRES TLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFF
CC	ATOM   TLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKL-------PFF
CC	       ****************************************       ***
CC	SEQRES LSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVD
CC	ATOM   LSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRL-------VD
CC	       *****************************************       **
CC	SEQRES FLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYE
CC	ATOM   FLQLMIDSQN-----SHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYE
CC	       **********     ***********************************
CC	SEQRES LATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIA
CC	ATOM   LATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIA
CC	       **************************************************
CC	SEQRES MRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFS
CC	ATOM   MRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFS
CC	       **************************************************
CC	SEQRES KKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKE
CC	ATOM   KKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKE
CC	       **************************************************
CC	SEQRES TQIPLKLSLGGLLQPEKPVVLKVESRDGTVSGAHHHH
CC	ATOM   TQIPLKLSLGGLLQPEKPVVLKVESR-----------
CC	       **************************           
SQ	SEQUENCE	487 AA;      MW;         CN;
	MAYLYGTHSH GLFKKLGIPG PTPLPFLGNI LSYHKGFCMF DMECHKKYGK VWGFYDGQQP
	VLAITDPDMI KTVLVKECYS VFTNRRPFGP VGFMKSAISI AEDEEWKRLR SLLSPTFTSG
	KLKEMVPIIA QYGDVLVRNL RREAETGKPV TLKDVFGAYS MDVITSTSFG VNIDSLNNPQ
	DPFVENTKKL LRFDFLDPFF LSITVFPFLI PILEVLNICV FPREVTNFLR KSVKRMKESR
	LEDTQKHRVD FLQLMIDSQN SKETESHKAL SDLELVAQSI IFIFAGYETT SSVLSFIMYE
	LATHPDVQQK LQEEIDAVLP NKAPPTYDTV LQMEYLDMVV NETLRLFPIA MRLERVCKKD
	VEINGMFIPK GVVVMIPSYA LHRDPKYWTE PEKFLPERFS KKNKDNIDPY IYTPFGSGPR
	NCIGMRFALM NMKLALIRVL QNFSFKPCKE TQIPLKLSLG GLLQPEKPVV LKVESRDGTV
	SGAHHHH
//