ID	6DACA	STANDARD;	PRT;	487	AA.
DT	CONVERTED FROM PDB (SEQRES) 6DAC
DE	Cytochrome P450 3A4
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.550
CC	R-Factor	0.212
FT	#HET	85	 105 	ARG	A	1	601 	HEM	A	S	12
FT	#HET	98	 118 	ILE	A	1	601 	HEM	A	A	4
FT	#HET	99	 119 	SER	A	1	601 	HEM	A	A	2
FT	#HET	99	 119 	SER	A	2	602 	FZV	A	S	2
FT	#HET	106	 126 	TRP	A	1	601 	HEM	A	S	5
FT	#HET	110	 130 	ARG	A	1	601 	HEM	A	S	5
FT	#HET	117	 137 	PHE	A	1	601 	HEM	A	S	2
FT	#HET	195	 215 	PHE	A	2	602 	FZV	A	S	13
FT	#HET	221	 241 	PHE	A	2	602 	FZV	A	S	11
FT	#HET	281	 301 	ILE	A	2	602 	FZV	A	S	6
FT	#HET	282	 302 	PHE	A	1	601 	HEM	A	S	3
FT	#HET	284	 304 	PHE	A	2	602 	FZV	A	S	10
FT	#HET	285	 305 	ALA	A	1	601 	HEM	A	A	6
FT	#HET	285	 305 	ALA	A	2	602 	FZV	A	A	6
FT	#HET	286	 306 	GLY	A	1	601 	HEM	A	B	1
FT	#HET	289	 309 	THR	A	1	601 	HEM	A	S	4
FT	#HET	289	 309 	THR	A	2	602 	FZV	A	S	2
FT	#HET	293	 313 	VAL	A	1	601 	HEM	A	S	1
FT	#HET	349	 369 	ILE	A	1	601 	HEM	A	S	2
FT	#HET	350	 370 	ALA	A	1	601 	HEM	A	S	1
FT	#HET	350	 370 	ALA	A	2	602 	FZV	A	B	2
FT	#HET	351	 371 	MET	A	2	602 	FZV	A	S	1
FT	#HET	353	 373 	LEU	A	1	601 	HEM	A	S	6
FT	#HET	355	 375 	ARG	A	1	601 	HEM	A	S	8
FT	#HET	414	 434 	PRO	A	1	601 	HEM	A	B	4
FT	#HET	415	 435 	PHE	A	1	601 	HEM	A	A	10
FT	#HET	416	 436 	GLY	A	1	601 	HEM	A	B	5
FT	#HET	417	 437 	SER	A	1	601 	HEM	A	B	2
FT	#HET	420	 440 	ARG	A	1	601 	HEM	A	A	13
FT	#HET	421	 441 	ASN	A	1	601 	HEM	A	B	4
FT	#HET	422	 442 	CYS	A	1	601 	HEM	A	A	25
FT	#HET	423	 443 	ILE	A	1	601 	HEM	A	S	2
FT	#HET	424	 444 	GLY	A	1	601 	HEM	A	B	4
FT	#HET	427	 447 	PHE	A	1	601 	HEM	A	S	1
FT	#HET	428	 448 	ALA	A	1	601 	HEM	A	S	3
FT	#HET	432	 452 	MET	A	1	601 	HEM	A	S	1
FT	DISORDER	1	6
FT	DISORDER	191	193
FT	DISORDER	244	248
FT	DISORDER	262	267
FT	DISORDER	477	487
CC	SEQUENCE	456 AA (ATOM);
CC	THSHGLFKKL GIPGPTPLPF LGNILSYHKG FCMFDMECHK KYGKVWGFYD GQQPVLAITD
CC	PDMIKTVLVK ECYSVFTNRR PFGPVGFMKS AISIAEDEEW KRLRSLLSPT FTSGKLKEMV
CC	PIIAQYGDVL VRNLRREAET GKPVTLKDVF GAYSMDVITS TSFGVNIDSL NNPQDPFVEN
CC	TKKLDFLDPF FLSITVFPFL IPILEVLNIC VFPREVTNFL RKSVKRMKES RLEDVDFLQL
CC	MIDSQNSKAL SDLELVAQSI IFIFAGYETT SSVLSFIMYE LATHPDVQQK LQEEIDAVLP
CC	NKAPPTYDTV LQMEYLDMVV NETLRLFPIA MRLERVCKKD VEINGMFIPK GVVVMIPSYA
CC	LHRDPKYWTE PEKFLPERFS KKNKDNIDPY IYTPFGSGPR NCIGMRFALM NMKLALIRVL
CC	QNFSFKPCKE TQIPLKLSLG GLLQPEKPVV LKVESR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGK
CC	ATOM   ------THSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGK
CC	             ********************************************
CC	SEQRES VWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISI
CC	ATOM   VWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISI
CC	       **************************************************
CC	SEQRES AEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPV
CC	ATOM   AEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPV
CC	       **************************************************
CC	SEQRES TLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFF
CC	ATOM   TLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKL---DFLDPFF
CC	       ****************************************   *******
CC	SEQRES LSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVD
CC	ATOM   LSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLED-----VD
CC	       *******************************************     **
CC	SEQRES FLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYE
CC	ATOM   FLQLMIDSQNS------KALSDLELVAQSIIFIFAGYETTSSVLSFIMYE
CC	       ***********      *********************************
CC	SEQRES LATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIA
CC	ATOM   LATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIA
CC	       **************************************************
CC	SEQRES MRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFS
CC	ATOM   MRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFS
CC	       **************************************************
CC	SEQRES KKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKE
CC	ATOM   KKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKE
CC	       **************************************************
CC	SEQRES TQIPLKLSLGGLLQPEKPVVLKVESRDGTVSGAHHHH
CC	ATOM   TQIPLKLSLGGLLQPEKPVVLKVESR-----------
CC	       **************************           
SQ	SEQUENCE	487 AA;      MW;         CN;
	MAYLYGTHSH GLFKKLGIPG PTPLPFLGNI LSYHKGFCMF DMECHKKYGK VWGFYDGQQP
	VLAITDPDMI KTVLVKECYS VFTNRRPFGP VGFMKSAISI AEDEEWKRLR SLLSPTFTSG
	KLKEMVPIIA QYGDVLVRNL RREAETGKPV TLKDVFGAYS MDVITSTSFG VNIDSLNNPQ
	DPFVENTKKL LRFDFLDPFF LSITVFPFLI PILEVLNICV FPREVTNFLR KSVKRMKESR
	LEDTQKHRVD FLQLMIDSQN SKETESHKAL SDLELVAQSI IFIFAGYETT SSVLSFIMYE
	LATHPDVQQK LQEEIDAVLP NKAPPTYDTV LQMEYLDMVV NETLRLFPIA MRLERVCKKD
	VEINGMFIPK GVVVMIPSYA LHRDPKYWTE PEKFLPERFS KKNKDNIDPY IYTPFGSGPR
	NCIGMRFALM NMKLALIRVL QNFSFKPCKE TQIPLKLSLG GLLQPEKPVV LKVESRDGTV
	SGAHHHH
//