ID	6CQ0A	STANDARD;	PRT;	660	AA.
DT	CONVERTED FROM PDB (SEQRES) 6CQ0
DE	Serine/threonine-protein kinase TBK1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	3.190
CC	R-Factor	0.241
FT	#HET	18	  15 	LEU	A	1	801 	F8M	A	S	16
FT	#HET	39	  36 	ALA	A	1	801 	F8M	A	S	3
FT	#HET	89	  86 	MET	A	1	801 	F8M	A	S	1
FT	#HET	90	  87 	GLU	A	1	801 	F8M	A	B	4
FT	#HET	91	  88 	PHE	A	1	801 	F8M	A	S	6
FT	#HET	92	  89 	CYS	A	1	801 	F8M	A	A	10
FT	#HET	93	  90 	PRO	A	1	801 	F8M	A	B	6
FT	#HET	145	 142 	MET	A	1	801 	F8M	A	S	5
FT	#HET	159	 156 	THR	A	1	801 	F8M	A	S	4
FT	DISORDER	1	2
FT	DISORDER	44	53
FT	DISORDER	164	177
FT	DISORDER	190	205
FT	DISORDER	483	496
CC	SEQUENCE	604 AA (ATOM);
CC	AMQSTSNHLW LLSDILGQGA TANVFRGRHK KTGDLFAIKV FVQMREFEVL KKLNHKNIVK
CC	LFAIEEETTT RHKVLIMEFC PCGSLYTVLE EPSNAYGLPE SEFLIVLRDV VGGMNHLREN
CC	GIVHRDIKPG NIMRVIGEDG QSVYKLTDFG AGTEEYLHPD MYEDLWSIGV TFYHAATGSL
CC	PFRPFEGPRR NKEVMYKIIT GKPSGAISGV QKAENGPIDW SGDMPVSCSL SRGLQVLLTP
CC	VLANILEADQ EKCWGFDQFF AETSDILHRM VIHVFSLQQM TAHKIYIHSY NTATIFHELV
CC	YKQTKIISSN QELIYEGRRL VLEPGRLAQH FPKTTEENPI FVVSREPLNT IGLIYEKISL
CC	PKVHPRYDLD GDASMAKAIT GVVCYACRIA STLLLYQELM RKGIRWLIEL IKDDYNETVH
CC	KKTEVVITLD FCIRNIEKTV ELGEISDIHT KLLRLSSSQG TIETSLQDID SRLSPGGSLA
CC	DAWAHQEGTH PKDRNVEKLQ VLLNCMTEIY YQFKKDKAER RLAYNEEQIH KFDKQKLYYH
CC	ATKAMTHFTD ECVKKYEAFL NKSEEWIRKM LHLRKQLLSL TNQCFDIEEE VSKYQEYTNE
CC	LQET
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES SNAMQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLR
CC	ATOM   --AMQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVF-------
CC	         *****************************************       
CC	SEQRES PVDVQMREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTV
CC	ATOM   ---VQMREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTV
CC	          ***********************************************
CC	SEQRES LEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGE
CC	ATOM   LEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGE
CC	       **************************************************
CC	SEQRES DGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDMYERAVLRKDHQKK
CC	ATOM   DGQSVYKLTDFGA--------------GTEEYLHPDMYE-----------
CC	       *************              ************           
CC	SEQRES YGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAIS
CC	ATOM   -----DLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAIS
CC	            *********************************************
CC	SEQRES GVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQ
CC	ATOM   GVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQ
CC	       **************************************************
CC	SEQRES FFAETSDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIIS
CC	ATOM   FFAETSDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIIS
CC	       **************************************************
CC	SEQRES SNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKI
CC	ATOM   SNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKI
CC	       **************************************************
CC	SEQRES SLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLI
CC	ATOM   SLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLI
CC	       **************************************************
CC	SEQRES ELIKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYEKLMKINLEAAELGE
CC	ATOM   ELIKDDYNETVHKKTEVVITLDFCIRNIEKTV--------------ELGE
CC	       ********************************              ****
CC	SEQRES ISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQEGTHPKDR
CC	ATOM   ISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQEGTHPKDR
CC	       **************************************************
CC	SEQRES NVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKA
CC	ATOM   NVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKA
CC	       **************************************************
CC	SEQRES MTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKY
CC	ATOM   MTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKY
CC	       **************************************************
CC	SEQRES QEYTNELQET
CC	ATOM   QEYTNELQET
CC	       **********
SQ	SEQUENCE	660 AA;      MW;         CN;
	SNAMQSTSNH LWLLSDILGQ GATANVFRGR HKKTGDLFAI KVFNNISFLR PVDVQMREFE
	VLKKLNHKNI VKLFAIEEET TTRHKVLIME FCPCGSLYTV LEEPSNAYGL PESEFLIVLR
	DVVGGMNHLR ENGIVHRDIK PGNIMRVIGE DGQSVYKLTD FGAARELEDD EQFVSLYGTE
	EYLHPDMYER AVLRKDHQKK YGATVDLWSI GVTFYHAATG SLPFRPFEGP RRNKEVMYKI
	ITGKPSGAIS GVQKAENGPI DWSGDMPVSC SLSRGLQVLL TPVLANILEA DQEKCWGFDQ
	FFAETSDILH RMVIHVFSLQ QMTAHKIYIH SYNTATIFHE LVYKQTKIIS SNQELIYEGR
	RLVLEPGRLA QHFPKTTEEN PIFVVSREPL NTIGLIYEKI SLPKVHPRYD LDGDASMAKA
	ITGVVCYACR IASTLLLYQE LMRKGIRWLI ELIKDDYNET VHKKTEVVIT LDFCIRNIEK
	TVKVYEKLMK INLEAAELGE ISDIHTKLLR LSSSQGTIET SLQDIDSRLS PGGSLADAWA
	HQEGTHPKDR NVEKLQVLLN CMTEIYYQFK KDKAERRLAY NEEQIHKFDK QKLYYHATKA
	MTHFTDECVK KYEAFLNKSE EWIRKMLHLR KQLLSLTNQC FDIEEEVSKY QEYTNELQET
//