ID	6C57A	STANDARD;	PRT;	322	AA.
DT	CONVERTED FROM PDB (SEQRES) 6C57
DE	Geranylgeranyl pyrophosphate synthase
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	3.500
CC	R-Factor	0.201
FT	#SUB	30	   8 	VAL	A	146	 124 	GLN	B	Protein	S	4
FT	#SUB	30	   8 	VAL	A	150	 128 	LEU	B	Protein	S	2
FT	#SUB	31	   9 	GLN	A	146	 124 	GLN	B	Protein	S	4
FT	#SUB	33	  11 	ILE	A	153	 131 	TYR	B	Protein	S	1
FT	#SUB	34	  12 	LEU	A	145	 123 	HIS	B	Protein	S	1
FT	#SUB	34	  12 	LEU	A	146	 124 	GLN	B	Protein	S	2
FT	#SUB	85	  63 	ILE	A	111	  89 	ILE	B	Protein	S	1
FT	#SUB	88	  66 	ILE	A	111	  89 	ILE	B	Protein	S	1
FT	#SUB	89	  67 	GLU	A	108	  86 	PRO	B	Protein	A	5
FT	#SUB	89	  67 	GLU	A	112	  90 	ASN	B	Protein	S	6
FT	#SUB	108	  86 	PRO	A	89	  67 	GLU	B	Protein	S	5
FT	#SUB	108	  86 	PRO	A	152	 130 	ILE	B	Protein	B	1
FT	#SUB	109	  87 	SER	A	152	 130 	ILE	B	Protein	B	1
FT	#SUB	109	  87 	SER	A	156	 134 	ASP	B	Protein	S	1
FT	#SUB	111	  89 	ILE	A	111	  89 	ILE	B	Protein	S	4
FT	#SUB	112	  90 	ASN	A	89	  67 	GLU	B	Protein	A	5
FT	#SUB	112	  90 	ASN	A	145	 123 	HIS	B	Protein	S	4
FT	#SUB	112	  90 	ASN	A	148	 126 	GLN	B	Protein	S	3
FT	#SUB	112	  90 	ASN	A	149	 127 	GLY	B	Protein	S	2
FT	#SUB	115	  93 	ASN	A	115	  93 	ASN	B	Protein	S	8
FT	#SUB	115	  93 	ASN	A	118	  96 	TYR	B	Protein	S	1
FT	#SUB	115	  93 	ASN	A	145	 123 	HIS	B	Protein	S	2
FT	#SUB	116	  94 	TYR	A	142	 120 	LEU	B	Protein	S	2
FT	#SUB	116	  94 	TYR	A	145	 123 	HIS	B	Protein	A	2
FT	#SUB	116	  94 	TYR	A	146	 124 	GLN	B	Protein	S	2
FT	#SUB	118	  96 	TYR	A	115	  93 	ASN	B	Protein	S	1
FT	#SUB	119	  97 	PHE	A	118	  96 	TYR	B	Protein	S	2
FT	#SUB	119	  97 	PHE	A	119	  97 	PHE	B	Protein	S	1
FT	#SUB	119	  97 	PHE	A	138	 116 	THR	B	Protein	B	1
FT	#SUB	119	  97 	PHE	A	141	 119 	LEU	B	Protein	S	4
FT	#SUB	119	  97 	PHE	A	142	 120 	LEU	B	Protein	A	3
FT	#SUB	119	  97 	PHE	A	145	 123 	HIS	B	Protein	S	3
FT	#SUB	120	  98 	LEU	A	142	 120 	LEU	B	Protein	A	3
FT	#SUB	122	 100 	LEU	A	122	 100 	LEU	B	Protein	S	2
FT	#SUB	122	 100 	LEU	A	138	 116 	THR	B	Protein	S	4
FT	#SUB	123	 101 	GLU	A	138	 116 	THR	B	Protein	A	3
FT	#SUB	123	 101 	GLU	A	142	 120 	LEU	B	Protein	S	2
FT	#SUB	126	 104 	LEU	A	134	 112 	VAL	B	Protein	S	1
FT	#SUB	126	 104 	LEU	A	135	 113 	LYS	B	Protein	S	2
FT	#SUB	134	 112 	VAL	A	126	 104 	LEU	B	Protein	S	1
FT	#SUB	135	 113 	LYS	A	126	 104 	LEU	B	Protein	B	1
FT	#SUB	138	 116 	THR	A	119	  97 	PHE	B	Protein	S	1
FT	#SUB	138	 116 	THR	A	122	 100 	LEU	B	Protein	S	3
FT	#SUB	138	 116 	THR	A	123	 101 	GLU	B	Protein	S	1
FT	#SUB	141	 119 	LEU	A	119	  97 	PHE	B	Protein	S	5
FT	#SUB	142	 120 	LEU	A	116	  94 	TYR	B	Protein	A	4
FT	#SUB	142	 120 	LEU	A	119	  97 	PHE	B	Protein	S	3
FT	#SUB	142	 120 	LEU	A	120	  98 	LEU	B	Protein	S	3
FT	#SUB	142	 120 	LEU	A	123	 101 	GLU	B	Protein	S	2
FT	#SUB	145	 123 	HIS	A	115	  93 	ASN	B	Protein	S	4
FT	#SUB	146	 124 	GLN	A	27	   5 	GLN	B	Protein	S	4
FT	#SUB	146	 124 	GLN	A	30	   8 	VAL	B	Protein	B	1
FT	#SUB	146	 124 	GLN	A	31	   9 	GLN	B	Protein	S	4
FT	#SUB	146	 124 	GLN	A	34	  12 	LEU	B	Protein	S	1
FT	#SUB	146	 124 	GLN	A	116	  94 	TYR	B	Protein	S	2
FT	#SUB	148	 126 	GLN	A	112	  90 	ASN	B	Protein	A	3
FT	#SUB	149	 127 	GLY	A	30	   8 	VAL	B	Protein	B	2
FT	#SUB	149	 127 	GLY	A	112	  90 	ASN	B	Protein	B	1
FT	#SUB	150	 128 	LEU	A	23	   1 	MET	B	Protein	S	1
FT	#SUB	150	 128 	LEU	A	27	   5 	GLN	B	Protein	S	1
FT	#SUB	150	 128 	LEU	A	30	   8 	VAL	B	Protein	A	2
FT	#SUB	152	 130 	ILE	A	108	  86 	PRO	B	Protein	S	1
FT	#SUB	152	 130 	ILE	A	112	  90 	ASN	B	Protein	S	1
FT	#SUB	153	 131 	TYR	A	29	   7 	THR	B	Protein	S	1
FT	#SUB	153	 131 	TYR	A	33	  11 	ILE	B	Protein	S	2
FT	#SUB	168	 146 	ALA	A	23	   1 	MET	B	Protein	S	1
FT	#SUB	172	 150 	GLN	A	23	   1 	MET	B	Protein	S	1
FT	#SUB	172	 150 	GLN	A	27	   5 	GLN	B	Protein	S	9
FT	DISORDER	1	18
FT	DISORDER	218	222
FT	DISORDER	247	254
FT	DISORDER	259	266
FT	DISORDER	317	322
CC	SEQUENCE	277 AA (ATOM);
CC	YFQSMEKTQE TVQRILLEPY KYLLQLPGKQ VRTKLSQAFN HWLKVPEDKL QIIIEVTEML
CC	HNASLLIDDI EDNSKLRRGF PVAHSIYGIP SVINSANYVY FLGLEKVLTL DHPDAVKLFT
CC	RQLLELHQGQ GLDIYWRDNY TCPTEEEYKA MVLQKTGGLF GLAVGLMQLF SDYKEDLKPL
CC	LNTLGLFFQI RDDYANLHSN KSFCEDLTEG KFSFPTIHAI WSRILRQKDC VHYLEDVGSF
CC	EYTRNTLKEL EAKAYKQIDA RGGNPELVAL VKHLSKM
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MHHHHHHSSGVDLGTENLYFQSMEKTQETVQRILLEPYKYLLQLPGKQVR
CC	ATOM   ------------------YFQSMEKTQETVQRILLEPYKYLLQLPGKQVR
CC	                         ********************************
CC	SEQRES TKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPV
CC	ATOM   TKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPV
CC	       **************************************************
CC	SEQRES AHSIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGL
CC	ATOM   AHSIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGL
CC	       **************************************************
CC	SEQRES DIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLN
CC	ATOM   DIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLN
CC	       **************************************************
CC	SEQRES TLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPEST
CC	ATOM   TLGLFFQIRDDYANLHS-----NKSFCEDLTEGKFSFPTIHAIWSR----
CC	       *****************     ************************    
CC	SEQRES QVQNILRQRTENIDIKKDCVHYLEDVGSFEYTRNTLKELEAKAYKQIDAR
CC	ATOM   ----ILRQ--------KDCVHYLEDVGSFEYTRNTLKELEAKAYKQIDAR
CC	           ****        **********************************
CC	SEQRES GGNPELVALVKHLSKMFKEENE
CC	ATOM   GGNPELVALVKHLSKM------
CC	       ****************      
SQ	SEQUENCE	322 AA;      MW;         CN;
	MHHHHHHSSG VDLGTENLYF QSMEKTQETV QRILLEPYKY LLQLPGKQVR TKLSQAFNHW
	LKVPEDKLQI IIEVTEMLHN ASLLIDDIED NSKLRRGFPV AHSIYGIPSV INSANYVYFL
	GLEKVLTLDH PDAVKLFTRQ LLELHQGQGL DIYWRDNYTC PTEEEYKAMV LQKTGGLFGL
	AVGLMQLFSD YKEDLKPLLN TLGLFFQIRD DYANLHSKEY SENKSFCEDL TEGKFSFPTI
	HAIWSRPEST QVQNILRQRT ENIDIKKDCV HYLEDVGSFE YTRNTLKELE AKAYKQIDAR
	GGNPELVALV KHLSKMFKEE NE
//
ID	6C57B	STANDARD;	PRT;	322	AA.
DT	CONVERTED FROM PDB (SEQRES) 6C57
DE	Geranylgeranyl pyrophosphate synthase
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	3.500
CC	R-Factor	0.201
FT	#SUB	23	   1 	MET	B	150	 128 	LEU	A	Protein	S	1
FT	#SUB	23	   1 	MET	B	168	 146 	ALA	A	Protein	S	1
FT	#SUB	23	   1 	MET	B	172	 150 	GLN	A	Protein	S	1
FT	#SUB	27	   5 	GLN	B	146	 124 	GLN	A	Protein	S	4
FT	#SUB	27	   5 	GLN	B	150	 128 	LEU	A	Protein	S	1
FT	#SUB	27	   5 	GLN	B	172	 150 	GLN	A	Protein	S	9
FT	#SUB	29	   7 	THR	B	153	 131 	TYR	A	Protein	S	1
FT	#SUB	30	   8 	VAL	B	146	 124 	GLN	A	Protein	S	1
FT	#SUB	30	   8 	VAL	B	149	 127 	GLY	A	Protein	S	2
FT	#SUB	30	   8 	VAL	B	150	 128 	LEU	A	Protein	S	2
FT	#SUB	31	   9 	GLN	B	146	 124 	GLN	A	Protein	S	4
FT	#SUB	33	  11 	ILE	B	153	 131 	TYR	A	Protein	S	2
FT	#SUB	34	  12 	LEU	B	146	 124 	GLN	A	Protein	S	1
FT	#SUB	89	  67 	GLU	B	108	  86 	PRO	A	Protein	A	5
FT	#SUB	89	  67 	GLU	B	112	  90 	ASN	A	Protein	S	5
FT	#SUB	108	  86 	PRO	B	89	  67 	GLU	A	Protein	A	5
FT	#SUB	108	  86 	PRO	B	152	 130 	ILE	A	Protein	S	1
FT	#SUB	111	  89 	ILE	B	85	  63 	ILE	A	Protein	S	1
FT	#SUB	111	  89 	ILE	B	88	  66 	ILE	A	Protein	S	1
FT	#SUB	111	  89 	ILE	B	111	  89 	ILE	A	Protein	S	4
FT	#SUB	112	  90 	ASN	B	89	  67 	GLU	A	Protein	A	6
FT	#SUB	112	  90 	ASN	B	148	 126 	GLN	A	Protein	S	3
FT	#SUB	112	  90 	ASN	B	149	 127 	GLY	A	Protein	S	1
FT	#SUB	112	  90 	ASN	B	152	 130 	ILE	A	Protein	S	1
FT	#SUB	115	  93 	ASN	B	115	  93 	ASN	A	Protein	S	8
FT	#SUB	115	  93 	ASN	B	118	  96 	TYR	A	Protein	S	1
FT	#SUB	115	  93 	ASN	B	145	 123 	HIS	A	Protein	S	4
FT	#SUB	116	  94 	TYR	B	142	 120 	LEU	A	Protein	A	4
FT	#SUB	116	  94 	TYR	B	146	 124 	GLN	A	Protein	S	2
FT	#SUB	118	  96 	TYR	B	115	  93 	ASN	A	Protein	S	1
FT	#SUB	118	  96 	TYR	B	119	  97 	PHE	A	Protein	S	2
FT	#SUB	119	  97 	PHE	B	119	  97 	PHE	A	Protein	S	1
FT	#SUB	119	  97 	PHE	B	138	 116 	THR	A	Protein	B	1
FT	#SUB	119	  97 	PHE	B	141	 119 	LEU	A	Protein	S	5
FT	#SUB	119	  97 	PHE	B	142	 120 	LEU	A	Protein	A	3
FT	#SUB	120	  98 	LEU	B	142	 120 	LEU	A	Protein	A	3
FT	#SUB	122	 100 	LEU	B	122	 100 	LEU	A	Protein	S	2
FT	#SUB	122	 100 	LEU	B	138	 116 	THR	A	Protein	S	3
FT	#SUB	123	 101 	GLU	B	138	 116 	THR	A	Protein	B	1
FT	#SUB	123	 101 	GLU	B	142	 120 	LEU	A	Protein	S	2
FT	#SUB	126	 104 	LEU	B	134	 112 	VAL	A	Protein	S	1
FT	#SUB	126	 104 	LEU	B	135	 113 	LYS	A	Protein	S	1
FT	#SUB	134	 112 	VAL	B	126	 104 	LEU	A	Protein	S	1
FT	#SUB	135	 113 	LYS	B	126	 104 	LEU	A	Protein	A	2
FT	#SUB	138	 116 	THR	B	119	  97 	PHE	A	Protein	S	1
FT	#SUB	138	 116 	THR	B	122	 100 	LEU	A	Protein	S	4
FT	#SUB	138	 116 	THR	B	123	 101 	GLU	A	Protein	S	3
FT	#SUB	141	 119 	LEU	B	119	  97 	PHE	A	Protein	S	4
FT	#SUB	142	 120 	LEU	B	116	  94 	TYR	A	Protein	A	2
FT	#SUB	142	 120 	LEU	B	119	  97 	PHE	A	Protein	S	3
FT	#SUB	142	 120 	LEU	B	120	  98 	LEU	A	Protein	S	3
FT	#SUB	142	 120 	LEU	B	123	 101 	GLU	A	Protein	S	2
FT	#SUB	145	 123 	HIS	B	34	  12 	LEU	A	Protein	B	1
FT	#SUB	145	 123 	HIS	B	112	  90 	ASN	A	Protein	A	4
FT	#SUB	145	 123 	HIS	B	115	  93 	ASN	A	Protein	S	2
FT	#SUB	145	 123 	HIS	B	116	  94 	TYR	A	Protein	S	2
FT	#SUB	145	 123 	HIS	B	119	  97 	PHE	A	Protein	S	3
FT	#SUB	146	 124 	GLN	B	30	   8 	VAL	A	Protein	A	4
FT	#SUB	146	 124 	GLN	B	31	   9 	GLN	A	Protein	S	4
FT	#SUB	146	 124 	GLN	B	34	  12 	LEU	A	Protein	A	2
FT	#SUB	146	 124 	GLN	B	116	  94 	TYR	A	Protein	S	2
FT	#SUB	148	 126 	GLN	B	112	  90 	ASN	A	Protein	A	3
FT	#SUB	149	 127 	GLY	B	112	  90 	ASN	A	Protein	B	2
FT	#SUB	150	 128 	LEU	B	30	   8 	VAL	A	Protein	S	2
FT	#SUB	152	 130 	ILE	B	108	  86 	PRO	A	Protein	S	1
FT	#SUB	152	 130 	ILE	B	109	  87 	SER	A	Protein	S	1
FT	#SUB	153	 131 	TYR	B	33	  11 	ILE	A	Protein	S	1
FT	#SUB	156	 134 	ASP	B	109	  87 	SER	A	Protein	S	1
FT	#HET	79	  57 	HIS	B	1	401 	FV9	B	S	7
FT	#HET	82	  60 	SER	B	1	401 	FV9	B	S	4
FT	#HET	83	  61 	LEU	B	1	401 	FV9	B	S	2
FT	#HET	95	  73 	ARG	B	1	401 	FV9	B	S	10
FT	#HET	96	  74 	ARG	B	1	401 	FV9	B	S	1
FT	#HET	144	 122 	LEU	B	1	401 	FV9	B	S	3
FT	#HET	173	 151 	LYS	B	1	401 	FV9	B	A	5
FT	#HET	174	 152 	THR	B	1	401 	FV9	B	A	12
FT	#HET	177	 155 	LEU	B	1	401 	FV9	B	S	6
FT	#HET	207	 185 	GLN	B	1	401 	FV9	B	A	8
FT	#HET	210	 188 	ASP	B	1	401 	FV9	B	S	9
FT	#HET	211	 189 	ASP	B	1	401 	FV9	B	S	2
FT	#HET	234	 212 	LYS	B	1	401 	FV9	B	S	7
FT	DISORDER	1	19
FT	DISORDER	217	230
FT	DISORDER	246	274
FT	DISORDER	317	322
CC	SEQUENCE	254 AA (ATOM);
CC	FQSMEKTQET VQRILLEPYK YLLQLPGKQV RTKLSQAFNH WLKVPEDKLQ IIIEVTEMLH
CC	NASLLIDDIE DNSKLRRGFP VAHSIYGIPS VINSANYVYF LGLEKVLTLD HPDAVKLFTR
CC	QLLELHQGQG LDIYWRDNYT CPTEEEYKAM VLQKTGGLFG LAVGLMQLFS DYKEDLKPLL
CC	NTLGLFFQIR DDYANLHTEG KFSFPTIHAI WSDVGSFEYT RNTLKELEAK AYKQIDARGG
CC	NPELVALVKH LSKM
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MHHHHHHSSGVDLGTENLYFQSMEKTQETVQRILLEPYKYLLQLPGKQVR
CC	ATOM   -------------------FQSMEKTQETVQRILLEPYKYLLQLPGKQVR
CC	                          *******************************
CC	SEQRES TKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPV
CC	ATOM   TKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPV
CC	       **************************************************
CC	SEQRES AHSIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGL
CC	ATOM   AHSIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGL
CC	       **************************************************
CC	SEQRES DIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLN
CC	ATOM   DIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLN
CC	       **************************************************
CC	SEQRES TLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPEST
CC	ATOM   TLGLFFQIRDDYANLH--------------TEGKFSFPTIHAIWS-----
CC	       ****************              ***************     
CC	SEQRES QVQNILRQRTENIDIKKDCVHYLEDVGSFEYTRNTLKELEAKAYKQIDAR
CC	ATOM   ------------------------DVGSFEYTRNTLKELEAKAYKQIDAR
CC	                               **************************
CC	SEQRES GGNPELVALVKHLSKMFKEENE
CC	ATOM   GGNPELVALVKHLSKM------
CC	       ****************      
SQ	SEQUENCE	322 AA;      MW;         CN;
	MHHHHHHSSG VDLGTENLYF QSMEKTQETV QRILLEPYKY LLQLPGKQVR TKLSQAFNHW
	LKVPEDKLQI IIEVTEMLHN ASLLIDDIED NSKLRRGFPV AHSIYGIPSV INSANYVYFL
	GLEKVLTLDH PDAVKLFTRQ LLELHQGQGL DIYWRDNYTC PTEEEYKAMV LQKTGGLFGL
	AVGLMQLFSD YKEDLKPLLN TLGLFFQIRD DYANLHSKEY SENKSFCEDL TEGKFSFPTI
	HAIWSRPEST QVQNILRQRT ENIDIKKDCV HYLEDVGSFE YTRNTLKELE AKAYKQIDAR
	GGNPELVALV KHLSKMFKEE NE
//