ID	6BKWA	STANDARD;	PRT;	287	AA.
DT	CONVERTED FROM PDB (SEQRES) 6BKW
DE	Tyrosine-protein kinase BTK
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.500
CC	R-Factor	0.164
FT	#HET	4	 395 	TRP	A	5	705 	FPZ	A	S	9
FT	#HET	15	 406 	LYS	A	6	706 	GOL	A	S	2
FT	#HET	17	 408 	LEU	A	4	704 	DXM	A	A	20
FT	#HET	17	 408 	LEU	A	6	706 	GOL	A	S	2
FT	#HET	18	 409 	GLY	A	4	704 	DXM	A	B	3
FT	#HET	19	 410 	THR	A	4	704 	DXM	A	B	4
FT	#HET	20	 411 	GLY	A	4	704 	DXM	A	B	2
FT	#HET	21	 412 	GLN	A	4	704 	DXM	A	S	5
FT	#HET	22	 413 	PHE	A	4	704 	DXM	A	S	9
FT	#HET	25	 416 	VAL	A	4	704 	DXM	A	S	11
FT	#HET	27	 418 	TYR	A	6	706 	GOL	A	S	13
FT	#HET	30	 421 	TRP	A	5	705 	FPZ	A	S	17
FT	#HET	34	 425 	TYR	A	5	705 	FPZ	A	A	38
FT	#HET	35	 426 	ASP	A	5	705 	FPZ	A	B	6
FT	#HET	37	 428 	ALA	A	4	704 	DXM	A	S	4
FT	#HET	39	 430 	LYS	A	4	704 	DXM	A	S	5
FT	#HET	67	 458 	VAL	A	4	704 	DXM	A	S	2
FT	#HET	70	 461 	TYR	A	5	705 	FPZ	A	A	33
FT	#HET	83	 474 	THR	A	4	704 	DXM	A	S	4
FT	#HET	84	 475 	GLU	A	4	704 	DXM	A	B	6
FT	#HET	85	 476 	TYR	A	4	704 	DXM	A	A	11
FT	#HET	85	 476 	TYR	A	6	706 	GOL	A	S	15
FT	#HET	86	 477 	MET	A	4	704 	DXM	A	A	10
FT	#HET	87	 478 	ALA	A	4	704 	DXM	A	B	9
FT	#HET	87	 478 	ALA	A	6	706 	GOL	A	S	1
FT	#HET	88	 479 	ASN	A	4	704 	DXM	A	B	2
FT	#HET	89	 480 	GLY	A	4	704 	DXM	A	B	8
FT	#HET	96	 487 	ARG	A	1	701 	SO4	A	S	8
FT	#HET	99	 490 	ARG	A	1	701 	SO4	A	S	7
FT	#HET	99	 490 	ARG	A	3	703 	SO4	A	S	4
FT	#HET	100	 491 	HIS	A	3	703 	SO4	A	S	6
FT	#HET	130	 521 	ASP	A	4	704 	DXM	A	S	7
FT	#HET	135	 526 	ASN	A	4	704 	DXM	A	S	10
FT	#HET	137	 528 	LEU	A	4	704 	DXM	A	S	7
FT	#HET	147	 538 	SER	A	4	704 	DXM	A	S	1
FT	#HET	148	 539 	ASP	A	4	704 	DXM	A	A	15
FT	#HET	151	 542 	LEU	A	4	704 	DXM	A	A	9
FT	#HET	152	 543 	SER	A	4	704 	DXM	A	A	7
FT	#HET	155	 546 	VAL	A	4	704 	DXM	A	S	4
FT	#HET	160	 551 	TYR	A	4	704 	DXM	A	S	12
FT	#HET	201	 592 	SER	A	2	702 	SO4	A	A	2
FT	#HET	204	 595 	LYS	A	1	701 	SO4	A	A	3
FT	#HET	204	 595 	LYS	A	2	702 	SO4	A	S	6
FT	#HET	226	 617 	TYR	A	2	702 	SO4	A	S	4
FT	#HET	227	 618 	ARG	A	7	707 	GOL	A	S	8
FT	#HET	228	 619 	PRO	A	2	702 	SO4	A	A	4
FT	#HET	229	 620 	HIS	A	2	702 	SO4	A	A	9
FT	#HET	229	 620 	HIS	A	7	707 	GOL	A	B	8
FT	#HET	230	 621 	LEU	A	7	707 	GOL	A	B	9
FT	#HET	231	 622 	ALA	A	7	707 	GOL	A	B	8
FT	#HET	232	 623 	SER	A	7	707 	GOL	A	B	6
FT	DISORDER	1	1
FT	DISORDER	268	287
CC	SEQUENCE	266 AA (ATOM);
CC	GSWEIDPKDL TFLKELGTGQ FGVVKYGKWR GQYDVAIKMI KEGSMSEDEF IEEAKVMMNL
CC	SHEKLVQLYG VCTKQRPIFI ITEYMANGXL LNYLREMRHR FQTQQLLEMC KDVCEAMEYL
CC	ESKQFLHRDL AARNCLVNDQ GVVKVSDFGL SRYVLDDEYT SSVGSKFPVR WSPPEVLMYS
CC	KFSSKSDIWA FGVLMWEIYS LGKMPYERFT NSETAEHIAQ GLRLYRPHLA SEKVYTIMYS
CC	CWHEKADERP TFKILLSNIL DVMDEN
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDE
CC	ATOM   -GSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDE
CC	        *************************************************
CC	SEQRES FIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGXLLNYLREMRH
CC	ATOM   FIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGXLLNYLREMRH
CC	       **************************************************
CC	SEQRES RFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFG
CC	ATOM   RFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFG
CC	       **************************************************
CC	SEQRES LSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIY
CC	ATOM   LSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIY
CC	       **************************************************
CC	SEQRES SLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADER
CC	ATOM   SLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADER
CC	       **************************************************
CC	SEQRES PTFKILLSNILDVMDENLYFQGEEYMPTEHHHHHHHH
CC	ATOM   PTFKILLSNILDVMDEN--------------------
CC	       *****************                    
SQ	SEQUENCE	287 AA;      MW;         CN;
	MGSWEIDPKD LTFLKELGTG QFGVVKYGKW RGQYDVAIKM IKEGSMSEDE FIEEAKVMMN
	LSHEKLVQLY GVCTKQRPIF IITEYMANGX LLNYLREMRH RFQTQQLLEM CKDVCEAMEY
	LESKQFLHRD LAARNCLVND QGVVKVSDFG LSRYVLDDEY TSSVGSKFPV RWSPPEVLMY
	SKFSSKSDIW AFGVLMWEIY SLGKMPYERF TNSETAEHIA QGLRLYRPHL ASEKVYTIMY
	SCWHEKADER PTFKILLSNI LDVMDENLYF QGEEYMPTEH HHHHHHH
//