ID	5YV8A	STANDARD;	PRT;	298	AA.
DT	CONVERTED FROM PDB (SEQRES) 5YV8
DE	Calcium/calmodulin-dependent protein kinase kinase 2
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.930
CC	R-Factor	0.166
FT	#HET	21	 171 	ILE	A	1	501 	91L	A	A	11
FT	#HET	22	 172 	GLY	A	1	501 	91L	A	B	1
FT	#HET	22	 172 	GLY	A	2	502 	GOL	A	B	2
FT	#HET	23	 173 	LYS	A	2	502 	GOL	A	B	5
FT	#HET	26	 176 	TYR	A	1	501 	91L	A	S	1
FT	#HET	26	 176 	TYR	A	2	502 	GOL	A	S	4
FT	#HET	29	 179 	VAL	A	1	501 	91L	A	S	3
FT	#HET	42	 192 	ALA	A	1	501 	91L	A	S	3
FT	#HET	44	 194 	LYS	A	1	501 	91L	A	S	5
FT	#HET	99	 249 	VAL	A	1	501 	91L	A	S	3
FT	#HET	117	 267 	PHE	A	1	501 	91L	A	S	9
FT	#HET	118	 268 	GLU	A	1	501 	91L	A	B	2
FT	#HET	119	 269 	LEU	A	1	501 	91L	A	A	3
FT	#HET	120	 270 	VAL	A	1	501 	91L	A	A	9
FT	#HET	124	 274 	PRO	A	2	502 	GOL	A	S	1
FT	#HET	138	 288 	GLN	A	3	503 	GOL	A	S	1
FT	#HET	141	 291 	PHE	A	3	503 	GOL	A	S	1
FT	#HET	142	 292 	TYR	A	3	503 	GOL	A	S	1
FT	#HET	164	 314 	LYS	A	6	506 	CL	A	S	2
FT	#HET	165	 315 	PRO	A	6	506 	CL	A	A	2
FT	#HET	166	 316 	SER	A	2	502 	GOL	A	B	4
FT	#HET	166	 316 	SER	A	6	506 	CL	A	A	3
FT	#HET	167	 317 	ASN	A	2	502 	GOL	A	S	3
FT	#HET	169	 319 	LEU	A	1	501 	91L	A	S	8
FT	#HET	169	 319 	LEU	A	2	502 	GOL	A	S	1
FT	#HET	179	 329 	ALA	A	1	501 	91L	A	A	3
FT	#HET	180	 330 	ASP	A	1	501 	91L	A	A	7
FT	#HET	187	 337 	PHE	A	4	504 	GOL	A	A	4
FT	#HET	188	 338 	LYS	A	4	504 	GOL	A	B	6
FT	#HET	191	 341 	ASP	A	4	504 	GOL	A	B	2
FT	#HET	192	 342 	ALA	A	4	504 	GOL	A	B	2
FT	#HET	193	 343 	LEU	A	4	504 	GOL	A	B	3
FT	#HET	282	 432 	GLU	A	5	505 	GOL	A	B	2
FT	#HET	283	 433 	SER	A	5	505 	GOL	A	B	1
FT	#HET	284	 434 	ARG	A	5	505 	GOL	A	B	4
FT	#HET	285	 435 	ILE	A	5	505 	GOL	A	B	1
FT	#HET	286	 436 	VAL	A	5	505 	GOL	A	S	1
FT	#HET	289	 439 	GLU	A	5	505 	GOL	A	S	11
FT	DISORDER	1	9
FT	DISORDER	50	78
CC	SEQUENCE	260 AA (ATOM);
CC	VQLNQYTLKD EIGKGSYGVV KLAYNENDNT YYAMKVLSKK PIEQVYQEIA ILKKLDHPNV
CC	VKLVEVLDDP NEDHLYMVFE LVNQGPVMEV PTLKPLSEDQ ARFYFQDLIK GIEYLHYQKI
CC	IHRDIKPSNL LVGEDGHIKI ADFGVSNEFK GSDALLSNTV GTPAFMAPES LSETRKIFSG
CC	KALDVWAMGV TLYCFVFGQC PFMDERIMCL HSKIKSQALE FPDQPDIAED LKDLITRMLD
CC	KNPESRIVVP EIKLHPWVTR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSSGSSGDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKK
CC	ATOM   ---------VQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKK-
CC	                **************************************** 
CC	SEQRES LIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVK
CC	ATOM   ----------------------------PIEQVYQEIAILKKLDHPNVVK
CC	                                   **********************
CC	SEQRES LVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGI
CC	ATOM   LVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGI
CC	       **************************************************
CC	SEQRES EYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGT
CC	ATOM   EYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGT
CC	       **************************************************
CC	SEQRES PAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHS
CC	ATOM   PAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHS
CC	       **************************************************
CC	SEQRES KIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTR
CC	ATOM   KIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTR
CC	       ************************************************
SQ	SEQUENCE	298 AA;      MW;         CN;
	GSSGSSGDCV QLNQYTLKDE IGKGSYGVVK LAYNENDNTY YAMKVLSKKK LIRQAGFPRR
	PPPRGTRPAP GGCIQPRGPI EQVYQEIAIL KKLDHPNVVK LVEVLDDPNE DHLYMVFELV
	NQGPVMEVPT LKPLSEDQAR FYFQDLIKGI EYLHYQKIIH RDIKPSNLLV GEDGHIKIAD
	FGVSNEFKGS DALLSNTVGT PAFMAPESLS ETRKIFSGKA LDVWAMGVTL YCFVFGQCPF
	MDERIMCLHS KIKSQALEFP DQPDIAEDLK DLITRMLDKN PESRIVVPEI KLHPWVTR
//