ID	5YGYA	STANDARD;	PRT;	416	AA.
DT	CONVERTED FROM PDB (SEQRES) 5YGY
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.300
CC	R-Factor	0.196
FT	#HET	19	  -4 	ARG	A	2	502 	IOD	A	S	1
FT	#HET	33	  10 	SER	A	8	508 	GOL	A	A	5
FT	#HET	34	  11 	GLY	A	8	508 	GOL	A	B	5
FT	#HET	34	  11 	GLY	A	9	509 	0B6	A	B	3
FT	#HET	35	  12 	GLN	A	9	509 	0B6	A	B	5
FT	#HET	36	  13 	GLY	A	9	509 	0B6	A	B	9
FT	#HET	37	  14 	TYR	A	9	509 	0B6	A	S	1
FT	#HET	53	  30 	LEU	A	9	509 	0B6	A	S	2
FT	#HET	55	  32 	ASP	A	9	509 	0B6	A	S	11
FT	#HET	57	  34 	GLY	A	9	509 	0B6	A	B	2
FT	#HET	58	  35 	SER	A	9	509 	0B6	A	S	2
FT	#HET	67	  44 	PRO	A	7	507 	GOL	A	A	3
FT	#HET	68	  45 	HIS	A	1	501 	IOD	A	S	1
FT	#HET	68	  45 	HIS	A	3	503 	IOD	A	S	1
FT	#HET	68	  45 	HIS	A	7	507 	GOL	A	B	2
FT	#HET	71	  48 	LEU	A	7	507 	GOL	A	B	2
FT	#HET	73	  50 	ARG	A	6	506 	GOL	A	A	3
FT	#HET	74	  51 	TYR	A	6	506 	GOL	A	A	6
FT	#HET	74	  51 	TYR	A	7	507 	GOL	A	S	6
FT	#HET	76	  53 	GLN	A	6	506 	GOL	A	S	6
FT	#HET	94	  71 	TYR	A	9	509 	0B6	A	S	9
FT	#HET	119	  96 	ARG	A	4	504 	IOD	A	B	1
FT	#HET	126	 103 	THR	A	1	501 	IOD	A	B	1
FT	#HET	127	 104 	GLU	A	1	501 	IOD	A	B	3
FT	#HET	128	 105 	SER	A	1	501 	IOD	A	A	2
FT	#HET	130	 107 	LYS	A	3	503 	IOD	A	B	1
FT	#HET	131	 108 	PHE	A	9	509 	0B6	A	S	5
FT	#HET	133	 110 	ILE	A	9	509 	0B6	A	S	1
FT	#HET	141	 118 	ILE	A	9	509 	0B6	A	S	2
FT	#HET	157	 134 	GLU	A	4	504 	IOD	A	S	1
FT	#HET	166	 143 	GLN	A	4	504 	IOD	A	S	1
FT	#HET	251	 228 	ASP	A	9	509 	0B6	A	S	5
FT	#HET	252	 229 	SER	A	9	509 	0B6	A	B	2
FT	#HET	253	 230 	GLY	A	9	509 	0B6	A	B	16
FT	#HET	254	 231 	THR	A	9	509 	0B6	A	B	3
FT	#HET	255	 232 	THR	A	8	508 	GOL	A	S	2
FT	#HET	255	 232 	THR	A	9	509 	0B6	A	A	8
FT	#HET	330	 307 	ARG	A	8	508 	GOL	A	S	10
FT	#HET	331	 308 	PRO	A	8	508 	GOL	A	B	2
FT	#HET	358	 335 	ALA	A	9	509 	0B6	A	S	1
FT	#HET	372	 349 	ARG	A	2	502 	IOD	A	S	1
FT	#HET	374	 351 	ARG	A	2	502 	IOD	A	S	1
FT	DISORDER	1	16
FT	DISORDER	180	190
FT	DISORDER	409	416
CC	Miss-SC	2
CC	SEQUENCE	381 AA (ATOM);
CC	GRRGSFVEMV DNLRGKSGQG YYVEMTVGSP PQTLNILVDT GSSNFAVGAA PHPFLHRYYQ
CC	RQLSSTYRDL RKGVYVPYTQ GKWEGELGTD LVSIPHGPNV TVRANIAAIT ESDKFFINGS
CC	NWEGILGLAY AEIARPDDSL EPFFDSLVKQ THVPNLFSLQ LCGASVGGSM IIGGIDHSLY
CC	TGSLWYTPIR REWYYEVIIV RVEINGQDLK MDCKEYNYDK SIVDSGTTNL RLPKKVFEAA
CC	VKSIKAASST EKFPDGFWLG EQLVCWQAGT TPWNIFPVIS LYLMGEVTNQ SFRITILPQQ
CC	YLRPVEDVAT SQDDCYKFAI SQSSTGTVMG AVIMEGFYVV FDRARKRIGF AVSACHVHDE
CC	FRTAAVEGPF VTLDMEDCGY N
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSHMLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTL
CC	ATOM   ----------------GRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTL
CC	                       **********************************
CC	SEQRES NILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWE
CC	ATOM   NILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWE
CC	       **************************************************
CC	SEQRES GELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA
CC	ATOM   GELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA
CC	       **************************************************
CC	SEQRES RPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG
CC	ATOM   RPDDSLEPFFDSLVKQTHVPNLFSLQLCG-----------ASVGGSMIIG
CC	       *****************************           **********
CC	SEQRES GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIV
CC	ATOM   GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIV
CC	       **************************************************
CC	SEQRES DSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPW
CC	ATOM   DSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPW
CC	       **************************************************
CC	SEQRES NIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQS
CC	ATOM   NIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQS
CC	       **************************************************
CC	SEQRES STGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTL
CC	ATOM   STGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTL
CC	       **************************************************
CC	SEQRES DMEDCGYNIPQTDEST
CC	ATOM   DMEDCGYN--------
CC	       ********        
SQ	SEQUENCE	416 AA;      MW;         CN;
	GSHMLPRETD EEPEEPGRRG SFVEMVDNLR GKSGQGYYVE MTVGSPPQTL NILVDTGSSN
	FAVGAAPHPF LHRYYQRQLS STYRDLRKGV YVPYTQGKWE GELGTDLVSI PHGPNVTVRA
	NIAAITESDK FFINGSNWEG ILGLAYAEIA RPDDSLEPFF DSLVKQTHVP NLFSLQLCGA
	GFPLNQSEVL ASVGGSMIIG GIDHSLYTGS LWYTPIRREW YYEVIIVRVE INGQDLKMDC
	KEYNYDKSIV DSGTTNLRLP KKVFEAAVKS IKAASSTEKF PDGFWLGEQL VCWQAGTTPW
	NIFPVISLYL MGEVTNQSFR ITILPQQYLR PVEDVATSQD DCYKFAISQS STGTVMGAVI
	MEGFYVVFDR ARKRIGFAVS ACHVHDEFRT AAVEGPFVTL DMEDCGYNIP QTDEST
//