ID	5WFJA	STANDARD;	PRT;	293	AA.
DT	CONVERTED FROM PDB (SEQRES) 5WFJ
DE	Tyrosine-protein kinase JAK3
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.480
CC	R-Factor	0.205
FT	#HET	21	 828 	LEU	A	1	4000 	9Z4	A	A	3
FT	#HET	29	 836 	VAL	A	1	4000 	9Z4	A	S	3
FT	#HET	46	 853 	ALA	A	1	4000 	9Z4	A	S	4
FT	#HET	77	 884 	VAL	A	1	4000 	9Z4	A	S	1
FT	#HET	95	 902 	MET	A	1	4000 	9Z4	A	S	6
FT	#HET	96	 903 	GLU	A	1	4000 	9Z4	A	B	3
FT	#HET	97	 904 	TYR	A	1	4000 	9Z4	A	A	5
FT	#HET	98	 905 	LEU	A	1	4000 	9Z4	A	A	4
FT	#HET	101	 908 	GLY	A	1	4000 	9Z4	A	B	2
FT	#HET	102	 909 	CYS	A	1	4000 	9Z4	A	S	7
FT	#HET	104	 911 	ARG	A	1	4000 	9Z4	A	S	2
FT	#HET	105	 912 	ASP	A	1	4000 	9Z4	A	S	1
FT	#HET	146	 953 	ARG	A	1	4000 	9Z4	A	B	5
FT	#HET	147	 954 	ASN	A	1	4000 	9Z4	A	A	2
FT	#HET	149	 956 	LEU	A	1	4000 	9Z4	A	S	9
FT	DISORDER	1	9
FT	DISORDER	23	26
FT	DISORDER	52	54
FT	DISORDER	87	90
FT	DISORDER	177	178
FT	DISORDER	232	236
FT	DISORDER	293	293
CC	SEQUENCE	265 AA (ATOM);
CC	FEERHLKYIS QLGGSVELCR YDPLGDNTGA LVAVKQLQPD QQRDFQREIQ ILKALHSDFI
CC	VKYRGVSYGP LRLVMEYLPS GCLRDFLQRH RARLDASRLL LYSSQICKGM EYLGSRRCVH
CC	RDLAARNILV ESEAHVKIAD FGLAKLLPLD KDYYVVPGQS PIFWYAPESL SDNIFSRQSD
CC	VWSFGVVLYE LFTYCDKSCS PSAEFLRMMV PALSRLLELL EEGQRLPAPP ACPAEVHELM
CC	KLCWAPSPQD RPSFSALGPQ LDMLW
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GPASQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQL
CC	ATOM   ---------FEERHLKYISQLG----GSVELCRYDPLGDNTGALVAVKQL
CC	                *************    ************************
CC	SEQRES QHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPS
CC	ATOM   Q---PDQQRDFQREIQILKALHSDFIVKYRGVSYGP----LRLVMEYLPS
CC	       *   ********************************    **********
CC	SEQRES GCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILV
CC	ATOM   GCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILV
CC	       **************************************************
CC	SEQRES ESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQ
CC	ATOM   ESEAHVKIADFGLAKLLPLDKDYYVV--PGQSPIFWYAPESLSDNIFSRQ
CC	       **************************  **********************
CC	SEQRES SDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGSERDVPALSRLLELLEEG
CC	ATOM   SDVWSFGVVLYELFTYCDKSCSPSAEFLRMM-----VPALSRLLELLEEG
CC	       *******************************     **************
CC	SEQRES QRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWS
CC	ATOM   QRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLW-
CC	       ****************************************** 
SQ	SEQUENCE	293 AA;      MW;         CN;
	GPASQDPTIF EERHLKYISQ LGKGNFGSVE LCRYDPLGDN TGALVAVKQL QHSGPDQQRD
	FQREIQILKA LHSDFIVKYR GVSYGPGRQS LRLVMEYLPS GCLRDFLQRH RARLDASRLL
	LYSSQICKGM EYLGSRRCVH RDLAARNILV ESEAHVKIAD FGLAKLLPLD KDYYVVREPG
	QSPIFWYAPE SLSDNIFSRQ SDVWSFGVVL YELFTYCDKS CSPSAEFLRM MGSERDVPAL
	SRLLELLEEG QRLPAPPACP AEVHELMKLC WAPSPQDRPS FSALGPQLDM LWS
//