ID	5VO2A	STANDARD;	PRT;	300	AA.
DT	CONVERTED FROM PDB (SEQRES) 5VO2
DE	Mitogen-activated protein kinase kinase kinase 12
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.960
CC	R-Factor	0.174
FT	#HET	20	 131 	VAL	A	1	501 	9FV	A	A	4
FT	#HET	21	 132 	GLY	A	1	501 	9FV	A	B	2
FT	#HET	22	 133 	SER	A	1	501 	9FV	A	B	2
FT	#HET	23	 134 	GLY	A	1	501 	9FV	A	B	2
FT	#HET	25	 136 	GLN	A	1	501 	9FV	A	S	8
FT	#HET	28	 139 	VAL	A	1	501 	9FV	A	S	5
FT	#HET	39	 150 	ALA	A	1	501 	9FV	A	S	5
FT	#HET	41	 152 	LYS	A	1	501 	9FV	A	S	1
FT	#HET	63	 174 	ILE	A	1	501 	9FV	A	S	1
FT	#HET	79	 190 	MET	A	1	501 	9FV	A	S	5
FT	#HET	80	 191 	GLU	A	1	501 	9FV	A	B	3
FT	#HET	81	 192 	PHE	A	1	501 	9FV	A	A	7
FT	#HET	82	 193 	CYS	A	1	501 	9FV	A	A	7
FT	#HET	83	 194 	ALA	A	1	501 	9FV	A	B	2
FT	#HET	84	 195 	GLN	A	1	501 	9FV	A	B	1
FT	#HET	85	 196 	GLY	A	1	501 	9FV	A	B	4
FT	#HET	86	 197 	GLN	A	1	501 	9FV	A	S	3
FT	#HET	132	 243 	LEU	A	1	501 	9FV	A	S	4
FT	DISORDER	1	5
FT	DISORDER	146	158
FT	DISORDER	288	300
CC	SEQUENCE	269 AA (ATOM);
CC	LWEVPFEEIL DLQWVGSGAQ GAVFLGRFHG EEVAVKKVRD LKETDIKHLR KLKHPNIITF
CC	KGVCTQAPCY CILMEFCAQG QLYEVLRAGR PVTPSLLVDW SMGIAGGMNY LHLHKIIHRD
CC	LKSPNMLITY DDVVKISDFG FAGTVAWMAP EVIRNEPVSE KVDIWSFGVV LWELLTGEIP
CC	YKDVDSSAII WGVGSNSLHL PVPSSCPDGF KILLRQCWNS KPRNRPSFRQ ILLHLDIASA
CC	DVLSTPQETY FKSQAEWREE VKLHFEKIK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MGSEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETD
CC	ATOM   -----LWEVPFEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETD
CC	            *********************************************
CC	SEQRES IKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPS
CC	ATOM   IKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPS
CC	       **************************************************
CC	SEQRES LLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKEL
CC	ATOM   LLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFG-----
CC	       *********************************************     
CC	SEQRES SDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYK
CC	ATOM   --------FAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYK
CC	               ******************************************
CC	SEQRES DVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQIL
CC	ATOM   DVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQIL
CC	       **************************************************
CC	SEQRES LHLDIASADVLSTPQETYFKSQAEWREEVKLHFEKIKSEGTGNSHHHHHH
CC	ATOM   LHLDIASADVLSTPQETYFKSQAEWREEVKLHFEKIK-------------
CC	       *************************************             
CC	SEQRES 
CC	ATOM   
CC	       
SQ	SEQUENCE	300 AA;      MW;         CN;
	MGSEDLWEVP FEEILDLQWV GSGAQGAVFL GRFHGEEVAV KKVRDLKETD IKHLRKLKHP
	NIITFKGVCT QAPCYCILME FCAQGQLYEV LRAGRPVTPS LLVDWSMGIA GGMNYLHLHK
	IIHRDLKSPN MLITYDDVVK ISDFGTSKEL SDKSTKMSFA GTVAWMAPEV IRNEPVSEKV
	DIWSFGVVLW ELLTGEIPYK DVDSSAIIWG VGSNSLHLPV PSSCPDGFKI LLRQCWNSKP
	RNRPSFRQIL LHLDIASADV LSTPQETYFK SQAEWREEVK LHFEKIKSEG TGNSHHHHHH
//