ID	5VCGA	STANDARD;	PRT;	487	AA.
DT	CONVERTED FROM PDB (SEQRES) 5VCG
DE	Cytochrome P450 3A4
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.200
CC	R-Factor	0.237
FT	#HET	13	  33 	PHE	A	4	604 	GOL	A	S	1
FT	#HET	18	  38 	ILE	A	4	604 	GOL	A	B	1
FT	#HET	19	  39 	PRO	A	4	604 	GOL	A	B	1
FT	#HET	20	  40 	GLY	A	4	604 	GOL	A	B	4
FT	#HET	22	  42 	THR	A	4	604 	GOL	A	A	3
FT	#HET	35	  55 	LYS	A	6	606 	GOL	A	B	2
FT	#HET	36	  56 	GLY	A	6	606 	GOL	A	B	7
FT	#HET	37	  57 	PHE	A	2	602 	08Y	A	S	5
FT	#HET	37	  57 	PHE	A	6	606 	GOL	A	A	6
FT	#HET	38	  58 	ALA	A	6	606 	GOL	A	A	7
FT	#HET	39	  59 	MET	A	6	606 	GOL	A	B	1
FT	#HET	55	  75 	TYR	A	4	604 	GOL	A	S	1
FT	#HET	56	  76 	ASP	A	2	602 	08Y	A	S	2
FT	#HET	85	 105 	ARG	A	1	601 	HEM	A	S	15
FT	#HET	85	 105 	ARG	A	2	602 	08Y	A	S	2
FT	#HET	88	 108 	PHE	A	2	602 	08Y	A	A	7
FT	#HET	98	 118 	ILE	A	1	601 	HEM	A	S	3
FT	#HET	99	 119 	SER	A	1	601 	HEM	A	A	2
FT	#HET	99	 119 	SER	A	2	602 	08Y	A	S	3
FT	#HET	100	 120 	ILE	A	2	602 	08Y	A	S	2
FT	#HET	106	 126 	TRP	A	1	601 	HEM	A	S	5
FT	#HET	110	 130 	ARG	A	1	601 	HEM	A	S	4
FT	#HET	117	 137 	PHE	A	1	601 	HEM	A	S	2
FT	#HET	192	 212 	ARG	A	2	602 	08Y	A	S	5
FT	#HET	195	 215 	PHE	A	2	602 	08Y	A	S	29
FT	#HET	204	 224 	THR	A	2	602 	08Y	A	S	1
FT	#HET	282	 302 	PHE	A	1	601 	HEM	A	B	1
FT	#HET	284	 304 	PHE	A	2	602 	08Y	A	S	5
FT	#HET	285	 305 	ALA	A	1	601 	HEM	A	S	1
FT	#HET	285	 305 	ALA	A	2	602 	08Y	A	A	7
FT	#HET	286	 306 	GLY	A	1	601 	HEM	A	B	2
FT	#HET	289	 309 	THR	A	1	601 	HEM	A	S	6
FT	#HET	289	 309 	THR	A	2	602 	08Y	A	S	2
FT	#HET	293	 313 	VAL	A	1	601 	HEM	A	S	1
FT	#HET	349	 369 	ILE	A	1	601 	HEM	A	S	3
FT	#HET	350	 370 	ALA	A	1	601 	HEM	A	S	1
FT	#HET	350	 370 	ALA	A	2	602 	08Y	A	S	1
FT	#HET	351	 371 	MET	A	6	606 	GOL	A	S	2
FT	#HET	352	 372 	ARG	A	2	602 	08Y	A	A	3
FT	#HET	353	 373 	LEU	A	1	601 	HEM	A	S	2
FT	#HET	354	 374 	GLU	A	2	602 	08Y	A	S	1
FT	#HET	355	 375 	ARG	A	1	601 	HEM	A	S	7
FT	#HET	386	 406 	LYS	A	5	605 	GOL	A	B	2
FT	#HET	387	 407 	TYR	A	3	603 	GOL	A	B	2
FT	#HET	387	 407 	TYR	A	5	605 	GOL	A	B	4
FT	#HET	388	 408 	TRP	A	3	603 	GOL	A	A	6
FT	#HET	389	 409 	THR	A	3	603 	GOL	A	A	5
FT	#HET	389	 409 	THR	A	5	605 	GOL	A	S	1
FT	#HET	398	 418 	ARG	A	3	603 	GOL	A	S	5
FT	#HET	414	 434 	PRO	A	1	601 	HEM	A	B	3
FT	#HET	415	 435 	PHE	A	1	601 	HEM	A	A	10
FT	#HET	416	 436 	GLY	A	1	601 	HEM	A	B	3
FT	#HET	417	 437 	SER	A	1	601 	HEM	A	B	1
FT	#HET	420	 440 	ARG	A	1	601 	HEM	A	A	13
FT	#HET	421	 441 	ASN	A	1	601 	HEM	A	B	4
FT	#HET	422	 442 	CYS	A	1	601 	HEM	A	A	27
FT	#HET	423	 443 	ILE	A	1	601 	HEM	A	S	3
FT	#HET	424	 444 	GLY	A	1	601 	HEM	A	B	1
FT	#HET	428	 448 	ALA	A	1	601 	HEM	A	S	2
FT	#HET	432	 452 	MET	A	1	601 	HEM	A	S	1
FT	#HET	457	 477 	LEU	A	6	606 	GOL	A	S	1
FT	#HET	458	 478 	SER	A	6	606 	GOL	A	B	5
FT	#HET	460	 480 	GLY	A	6	606 	GOL	A	B	3
FT	#HET	462	 482 	LEU	A	6	606 	GOL	A	B	2
FT	#HET	463	 483 	LEU	A	6	606 	GOL	A	S	1
FT	DISORDER	1	7
FT	DISORDER	244	246
FT	DISORDER	262	267
FT	DISORDER	478	487
CC	SEQUENCE	461 AA (ATOM);
CC	HSHGLFKKLG IPGPTPLPFL GNILSYHKGF AMFDMEMHKK YGKVWGFYDG QQPVLAITDP
CC	DMIKTVLVKE AYSVFTNRRP FGPVGFMKSA ISIAEDEEWK RLRSLLSPTF TSGKLKEMVP
CC	IIAQYGDVLV RNLRREAETG KPVTLKDVFG AYSMDVITST SFGVNIDSLN NPQDPFVENT
CC	KKLLRFDFLD PFFLSITVFP FLIPILEVLN ITVFPREVTN FLRKSVKRMK ESRLEDHRVD
CC	FLQLMIDSQN SKALSDLELV AQSIIFIFAG YETTSSVLSF IMYELATHPD VQQKLQEEID
CC	AVLPNKAPPT YDTVLQMEYL DMVVNETLRL FPIAMRLERV AKKDVEINGM FIPKGVVVMI
CC	PSYALHRDPK YWTEPEKFLP ERFSKKNKDN IDPYIYTPFG SGPRNCIGMR FALMNMKLAL
CC	IRVLQNFSFK PSKETQIPLK LSLGGLLQPE KPVVLKVESR D
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFAMFDMEMHKKYGK
CC	ATOM   -------HSHGLFKKLGIPGPTPLPFLGNILSYHKGFAMFDMEMHKKYGK
CC	              *******************************************
CC	SEQRES VWGFYDGQQPVLAITDPDMIKTVLVKEAYSVFTNRRPFGPVGFMKSAISI
CC	ATOM   VWGFYDGQQPVLAITDPDMIKTVLVKEAYSVFTNRRPFGPVGFMKSAISI
CC	       **************************************************
CC	SEQRES AEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPV
CC	ATOM   AEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPV
CC	       **************************************************
CC	SEQRES TLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFF
CC	ATOM   TLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFF
CC	       **************************************************
CC	SEQRES LSITVFPFLIPILEVLNITVFPREVTNFLRKSVKRMKESRLEDTQKHRVD
CC	ATOM   LSITVFPFLIPILEVLNITVFPREVTNFLRKSVKRMKESRLED---HRVD
CC	       *******************************************   ****
CC	SEQRES FLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYE
CC	ATOM   FLQLMIDSQNS------KALSDLELVAQSIIFIFAGYETTSSVLSFIMYE
CC	       ***********      *********************************
CC	SEQRES LATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIA
CC	ATOM   LATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIA
CC	       **************************************************
CC	SEQRES MRLERVAKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFS
CC	ATOM   MRLERVAKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFS
CC	       **************************************************
CC	SEQRES KKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPSKE
CC	ATOM   KKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPSKE
CC	       **************************************************
CC	SEQRES TQIPLKLSLGGLLQPEKPVVLKVESRDGTVSGAHHHH
CC	ATOM   TQIPLKLSLGGLLQPEKPVVLKVESRD----------
CC	       ***************************          
SQ	SEQUENCE	487 AA;      MW;         CN;
	MAYLYGTHSH GLFKKLGIPG PTPLPFLGNI LSYHKGFAMF DMEMHKKYGK VWGFYDGQQP
	VLAITDPDMI KTVLVKEAYS VFTNRRPFGP VGFMKSAISI AEDEEWKRLR SLLSPTFTSG
	KLKEMVPIIA QYGDVLVRNL RREAETGKPV TLKDVFGAYS MDVITSTSFG VNIDSLNNPQ
	DPFVENTKKL LRFDFLDPFF LSITVFPFLI PILEVLNITV FPREVTNFLR KSVKRMKESR
	LEDTQKHRVD FLQLMIDSQN SKETESHKAL SDLELVAQSI IFIFAGYETT SSVLSFIMYE
	LATHPDVQQK LQEEIDAVLP NKAPPTYDTV LQMEYLDMVV NETLRLFPIA MRLERVAKKD
	VEINGMFIPK GVVVMIPSYA LHRDPKYWTE PEKFLPERFS KKNKDNIDPY IYTPFGSGPR
	NCIGMRFALM NMKLALIRVL QNFSFKPSKE TQIPLKLSLG GLLQPEKPVV LKVESRDGTV
	SGAHHHH
//