ID	5QJ1A	STANDARD;	PRT;	574	AA.
DT	CONVERTED FROM PDB (SEQRES) 5QJ1
DE	RNA-dependent RNA polymerase
OS	Hepacivirus C
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.170
CC	R-Factor	0.179
FT	#HET	5	   4 	TYR	A	13	613 	GOL	A	S	6
FT	#HET	25	  24 	ASN	A	2	602 	SO4	A	S	4
FT	#HET	28	  27 	SER	A	2	602 	SO4	A	S	8
FT	#HET	31	  30 	SER	A	2	602 	SO4	A	A	3
FT	#HET	49	  48 	ARG	A	13	613 	GOL	A	S	4
FT	#HET	53	  52 	VAL	A	13	613 	GOL	A	S	4
FT	#HET	94	  93 	PRO	A	5	605 	SO4	A	S	5
FT	#HET	95	  94 	PRO	A	9	609 	SO4	A	B	1
FT	#HET	96	  95 	HIS	A	9	609 	SO4	A	A	2
FT	#HET	97	  96 	SER	A	5	605 	SO4	A	S	4
FT	#HET	99	  98 	ARG	A	9	609 	SO4	A	S	1
FT	#HET	101	 100 	LYS	A	16	616 	PG4	A	S	21
FT	#HET	102	 101 	TYR	A	16	616 	PG4	A	S	2
FT	#HET	102	 101 	TYR	A	18	618 	PG4	A	S	1
FT	#HET	105	 104 	GLY	A	9	609 	SO4	A	B	2
FT	#HET	106	 105 	ALA	A	9	609 	SO4	A	A	4
FT	#HET	107	 106 	LYS	A	9	609 	SO4	A	A	5
FT	#HET	108	 107 	GLU	A	9	609 	SO4	A	S	1
FT	#HET	119	 118 	HIS	A	18	618 	PG4	A	S	4
FT	#HET	122	 121 	SER	A	18	618 	PG4	A	S	4
FT	#HET	126	 125 	ASP	A	18	618 	PG4	A	S	5
FT	#HET	136	 135 	PRO	A	16	616 	PG4	A	S	4
FT	#HET	137	 136 	THR	A	16	616 	PG4	A	B	1
FT	#HET	138	 137 	THR	A	16	616 	PG4	A	S	4
FT	#HET	146	 145 	PHE	A	17	617 	PG4	A	S	2
FT	#HET	147	 146 	CYS	A	17	617 	PG4	A	B	2
FT	#HET	159	 158 	ARG	A	13	613 	GOL	A	A	6
FT	#HET	160	 159 	LEU	A	13	613 	GOL	A	A	7
FT	#HET	165	 164 	ASP	A	16	616 	PG4	A	S	1
FT	#HET	169	 168 	ARG	A	5	605 	SO4	A	S	7
FT	#HET	173	 172 	LYS	A	5	605 	SO4	A	S	4
FT	#HET	188	 187 	MET	A	10	610 	SO4	A	B	1
FT	#HET	189	 188 	GLY	A	10	610 	SO4	A	B	3
FT	#HET	190	 189 	ALA	A	10	610 	SO4	A	A	6
FT	#HET	194	 193 	PHE	A	1	601 	J6J	A	A	14
FT	#HET	195	 194 	GLN	A	1	601 	J6J	A	B	3
FT	#HET	196	 195 	TYR	A	1	601 	J6J	A	B	10
FT	#HET	197	 196 	SER	A	1	601 	J6J	A	A	8
FT	#HET	198	 197 	PRO	A	1	601 	J6J	A	S	5
FT	#HET	201	 200 	ARG	A	1	601 	J6J	A	S	23
FT	#HET	205	 204 	LEU	A	1	601 	J6J	A	S	8
FT	#HET	226	 225 	ASP	A	13	613 	GOL	A	S	1
FT	#HET	227	 226 	SER	A	13	613 	GOL	A	A	3
FT	#HET	247	 246 	PRO	A	14	614 	GOL	A	A	5
FT	#HET	248	 247 	GLU	A	14	614 	GOL	A	A	12
FT	#HET	249	 248 	GLU	A	14	614 	GOL	A	A	3
FT	#HET	268	 267 	PHE	A	16	616 	PG4	A	S	3
FT	#HET	269	 268 	ASN	A	16	616 	PG4	A	B	2
FT	#HET	270	 269 	SER	A	16	616 	PG4	A	B	1
FT	#HET	271	 270 	LYS	A	16	616 	PG4	A	B	2
FT	#HET	272	 271 	GLY	A	16	616 	PG4	A	B	6
FT	#HET	273	 272 	GLN	A	6	606 	SO4	A	B	2
FT	#HET	274	 273 	THR	A	6	606 	SO4	A	A	8
FT	#HET	315	 314 	LEU	A	1	601 	J6J	A	A	14
FT	#HET	316	 315 	VAL	A	1	601 	J6J	A	B	3
FT	#HET	317	 316 	CYS	A	1	601 	J6J	A	A	5
FT	#HET	320	 319 	ASP	A	1	601 	J6J	A	A	6
FT	#HET	321	 320 	LEU	A	1	601 	J6J	A	B	5
FT	#HET	322	 321 	VAL	A	1	601 	J6J	A	A	11
FT	#HET	362	 361 	GLU	A	8	608 	SO4	A	S	1
FT	#HET	364	 363 	ILE	A	1	601 	J6J	A	A	7
FT	#HET	366	 365 	SER	A	1	601 	J6J	A	A	23
FT	#HET	367	 366 	CYS	A	1	601 	J6J	A	A	13
FT	#HET	368	 367 	SER	A	17	617 	PG4	A	S	3
FT	#HET	369	 368 	SER	A	1	601 	J6J	A	A	15
FT	#HET	370	 369 	ASN	A	1	601 	J6J	A	B	2
FT	#HET	372	 371 	SER	A	8	608 	SO4	A	A	6
FT	#HET	373	 372 	VAL	A	8	608 	SO4	A	B	1
FT	#HET	376	 375 	GLY	A	7	607 	SO4	A	B	5
FT	#HET	377	 376 	PRO	A	7	607 	SO4	A	A	5
FT	#HET	378	 377 	ARG	A	7	607 	SO4	A	A	18
FT	#HET	379	 378 	GLY	A	7	607 	SO4	A	B	1
FT	#HET	380	 379 	ARG	A	7	607 	SO4	A	A	15
FT	#HET	382	 381 	ARG	A	7	607 	SO4	A	S	3
FT	#HET	385	 384 	LEU	A	1	601 	J6J	A	S	11
FT	#HET	387	 386 	ARG	A	17	617 	PG4	A	S	9
FT	#HET	391	 390 	THR	A	17	617 	PG4	A	S	9
FT	#HET	395	 394 	ARG	A	17	617 	PG4	A	S	5
FT	#HET	415	 414 	GLN	A	1	601 	J6J	A	A	31
FT	#HET	416	 415 	TYR	A	1	601 	J6J	A	S	18
FT	#HET	423	 422 	ARG	A	3	603 	SO4	A	S	3
FT	#HET	448	 447 	MET	A	1	601 	J6J	A	S	2
FT	#HET	449	 448 	TYR	A	1	601 	J6J	A	S	30
FT	#HET	465	 464 	GLU	A	15	615 	GOL	A	A	8
FT	#HET	467	 466 	LEU	A	1	601 	J6J	A	S	7
FT	#HET	469	 468 	GLY	A	15	615 	GOL	A	B	4
FT	#HET	470	 469 	LEU	A	15	615 	GOL	A	A	4
FT	#HET	473	 472 	PHE	A	3	603 	SO4	A	B	1
FT	#HET	474	 473 	SER	A	3	603 	SO4	A	B	5
FT	#HET	475	 474 	MET	A	3	603 	SO4	A	B	3
FT	#HET	476	 475 	HIS	A	3	603 	SO4	A	A	10
FT	#HET	479	 478 	SER	A	8	608 	SO4	A	S	8
FT	#HET	481	 480 	HIS	A	8	608 	SO4	A	S	1
FT	#HET	497	 496 	PRO	A	12	612 	SO4	A	A	3
FT	#HET	498	 497 	LEU	A	12	612 	SO4	A	A	5
FT	#HET	499	 498 	ARG	A	12	612 	SO4	A	A	12
FT	#HET	506	 505 	ARG	A	4	604 	SO4	A	S	8
FT	#HET	509	 508 	ARG	A	11	611 	SO4	A	S	6
FT	#HET	513	 512 	ILE	A	11	611 	SO4	A	S	2
FT	#HET	524	 523 	ARG	A	11	611 	SO4	A	S	6
FT	#HET	528	 527 	ASN	A	3	603 	SO4	A	B	2
FT	#HET	529	 528 	TRP	A	3	603 	SO4	A	A	7
FT	#HET	531	 530 	VAL	A	4	604 	SO4	A	A	5
FT	#HET	532	 531 	LYS	A	4	604 	SO4	A	A	7
FT	#HET	533	 532 	THR	A	4	604 	SO4	A	A	5
FT	#HET	534	 533 	LYS	A	3	603 	SO4	A	S	6
FT	#HET	535	 534 	LEU	A	11	611 	SO4	A	S	3
FT	DISORDER	1	1
FT	DISORDER	150	153
FT	DISORDER	549	574
CC	SEQUENCE	543 AA (ATOM);
CC	SMSYSWTGAL ITPCSPEEEK LPINPLSNSS LRYHNKVYCT TSKSASQRAK KVTFDRTQVL
CC	DAHYDSVLKD IKLAASKVSA RLLTLEEACQ LTPPHSARSK YGFGAKEVRS LSGRAVNHIK
CC	SVWKDLLEDP QTPIPTTIMA KNEVFCVDGK KPARLIVYPD LGVRVCEKMA LYDITQKLPQ
CC	AVMGASYGFQ YSPAQRVEYL LKAWAEKKDP MGFSYDTRCF DSTVTERDIR TEESIYQACS
CC	LPEEARTAIH SLTERLYVGG PMFNSKGQTC GYRRCRASGV LTTSMGNTIT CYVKALAACK
CC	AAGIVAPTML VCGDDLVVIS ESQGTEEDER NLRAFTEAMT RYSAPPGDPP RPEYDLELIT
CC	SCSSNVSVAL GPRGRRRYYL TRDPTTPLAR AAWETVRHSP INSWLGNIIQ YAPTIWVRMV
CC	LMTHFFSILM VQDTLDQNLN FEMYGSVYSV NPLDLPAIIE RLHGLDAFSM HTYSHHELTR
CC	VASALRKLGA PPLRVWKSRA RAVRASLISR GGKAAVCGRY LFNWAVKTKL KLTPLPEARL
CC	LDL
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MSMSYSWTGALITPCSPEEEKLPINPLSNSSLRYHNKVYCTTSKSASQRA
CC	ATOM   -SMSYSWTGALITPCSPEEEKLPINPLSNSSLRYHNKVYCTTSKSASQRA
CC	        *************************************************
CC	SEQRES KKVTFDRTQVLDAHYDSVLKDIKLAASKVSARLLTLEEACQLTPPHSARS
CC	ATOM   KKVTFDRTQVLDAHYDSVLKDIKLAASKVSARLLTLEEACQLTPPHSARS
CC	       **************************************************
CC	SEQRES KYGFGAKEVRSLSGRAVNHIKSVWKDLLEDPQTPIPTTIMAKNEVFCVDP
CC	ATOM   KYGFGAKEVRSLSGRAVNHIKSVWKDLLEDPQTPIPTTIMAKNEVFCVD-
CC	       ************************************************* 
CC	SEQRES AKGGKKPARLIVYPDLGVRVCEKMALYDITQKLPQAVMGASYGFQYSPAQ
CC	ATOM   ---GKKPARLIVYPDLGVRVCEKMALYDITQKLPQAVMGASYGFQYSPAQ
CC	          ***********************************************
CC	SEQRES RVEYLLKAWAEKKDPMGFSYDTRCFDSTVTERDIRTEESIYQACSLPEEA
CC	ATOM   RVEYLLKAWAEKKDPMGFSYDTRCFDSTVTERDIRTEESIYQACSLPEEA
CC	       **************************************************
CC	SEQRES RTAIHSLTERLYVGGPMFNSKGQTCGYRRCRASGVLTTSMGNTITCYVKA
CC	ATOM   RTAIHSLTERLYVGGPMFNSKGQTCGYRRCRASGVLTTSMGNTITCYVKA
CC	       **************************************************
CC	SEQRES LAACKAAGIVAPTMLVCGDDLVVISESQGTEEDERNLRAFTEAMTRYSAP
CC	ATOM   LAACKAAGIVAPTMLVCGDDLVVISESQGTEEDERNLRAFTEAMTRYSAP
CC	       **************************************************
CC	SEQRES PGDPPRPEYDLELITSCSSNVSVALGPRGRRRYYLTRDPTTPLARAAWET
CC	ATOM   PGDPPRPEYDLELITSCSSNVSVALGPRGRRRYYLTRDPTTPLARAAWET
CC	       **************************************************
CC	SEQRES VRHSPINSWLGNIIQYAPTIWVRMVLMTHFFSILMVQDTLDQNLNFEMYG
CC	ATOM   VRHSPINSWLGNIIQYAPTIWVRMVLMTHFFSILMVQDTLDQNLNFEMYG
CC	       **************************************************
CC	SEQRES SVYSVNPLDLPAIIERLHGLDAFSMHTYSHHELTRVASALRKLGAPPLRV
CC	ATOM   SVYSVNPLDLPAIIERLHGLDAFSMHTYSHHELTRVASALRKLGAPPLRV
CC	       **************************************************
CC	SEQRES WKSRARAVRASLISRGGKAAVCGRYLFNWAVKTKLKLTPLPEARLLDLSS
CC	ATOM   WKSRARAVRASLISRGGKAAVCGRYLFNWAVKTKLKLTPLPEARLLDL--
CC	       ************************************************  
CC	SEQRES WFTVGAGGGDIFHSVSRARPRSLL
CC	ATOM   ------------------------
CC	                               
SQ	SEQUENCE	574 AA;      MW;         CN;
	MSMSYSWTGA LITPCSPEEE KLPINPLSNS SLRYHNKVYC TTSKSASQRA KKVTFDRTQV
	LDAHYDSVLK DIKLAASKVS ARLLTLEEAC QLTPPHSARS KYGFGAKEVR SLSGRAVNHI
	KSVWKDLLED PQTPIPTTIM AKNEVFCVDP AKGGKKPARL IVYPDLGVRV CEKMALYDIT
	QKLPQAVMGA SYGFQYSPAQ RVEYLLKAWA EKKDPMGFSY DTRCFDSTVT ERDIRTEESI
	YQACSLPEEA RTAIHSLTER LYVGGPMFNS KGQTCGYRRC RASGVLTTSM GNTITCYVKA
	LAACKAAGIV APTMLVCGDD LVVISESQGT EEDERNLRAF TEAMTRYSAP PGDPPRPEYD
	LELITSCSSN VSVALGPRGR RRYYLTRDPT TPLARAAWET VRHSPINSWL GNIIQYAPTI
	WVRMVLMTHF FSILMVQDTL DQNLNFEMYG SVYSVNPLDL PAIIERLHGL DAFSMHTYSH
	HELTRVASAL RKLGAPPLRV WKSRARAVRA SLISRGGKAA VCGRYLFNWA VKTKLKLTPL
	PEARLLDLSS WFTVGAGGGD IFHSVSRARP RSLL
//