ID	5O83A	STANDARD;	PRT;	941	AA.
DT	CONVERTED FROM PDB (SEQRES) 5O83
DE	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isof
DE	orm
OS	Mus musculus
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.900
CC	R-Factor	0.233
FT	#HET	647	 750 	THR	A	1	1101 	9NQ	A	S	1
FT	#HET	649	 752 	MET	A	1	1101 	9NQ	A	S	10
FT	#HET	655	 758 	PRO	A	1	1101 	9NQ	A	S	4
FT	#HET	657	 760 	TRP	A	1	1101 	9NQ	A	S	12
FT	#HET	674	 777 	ILE	A	1	1101 	9NQ	A	S	5
FT	#HET	676	 779 	LYS	A	1	1101 	9NQ	A	S	7
FT	#HET	684	 787 	ASP	A	1	1101 	9NQ	A	S	3
FT	#HET	710	 813 	TYR	A	1	1101 	9NQ	A	S	5
FT	#HET	722	 825 	ILE	A	1	1101 	9NQ	A	S	6
FT	#HET	723	 826 	GLU	A	1	1101 	9NQ	A	B	1
FT	#HET	724	 827 	VAL	A	1	1101 	9NQ	A	B	2
FT	#HET	725	 828 	VAL	A	1	1101 	9NQ	A	A	7
FT	#HET	728	 831 	SER	A	1	1101 	9NQ	A	S	3
FT	#HET	730	 833 	THR	A	1	1101 	9NQ	A	S	1
FT	#HET	797	 900 	MET	A	1	1101 	9NQ	A	S	8
FT	#HET	807	 910 	ILE	A	1	1101 	9NQ	A	S	3
FT	#HET	808	 911 	ASP	A	1	1101 	9NQ	A	S	3
FT	DISORDER	1	5
FT	DISORDER	71	83
FT	DISORDER	128	131
FT	DISORDER	166	166
FT	DISORDER	189	213
FT	DISORDER	223	223
FT	DISORDER	234	235
FT	DISORDER	260	262
FT	DISORDER	269	272
FT	DISORDER	295	311
FT	DISORDER	343	349
FT	DISORDER	377	378
FT	DISORDER	392	419
FT	DISORDER	738	744
FT	DISORDER	816	826
FT	DISORDER	925	941
CC	Miss-BB	1
CC	Miss-SC	1
CC	SEQUENCE	794 AA (ATOM);
CC	VKKLINSQIS LLIGKGLHEF DSLRDPEVND FRTKMRQFCE EAAAHRQQLG WVEWLQYSFP
CC	LQLEPNRALL VNVKFEGSEE SFTFQVSTKD MPLALMACAL RKKATVFRQQ PEEYALQVNG
CC	RHEYLYGNYP LCHFQYICSC LHSLTPHLTM VHSSSILAMR DEQSNWSLEQ PFSILIEGRK
CC	VNADMKLVVQ AGLFHGNEML CKTVSSSECS EPVWEFDISV CDLPRMARLC FALYAVDCPI
CC	AWANLMLFDY KDQLKTGERC LYMWPSVLNP AGTVRGNPNT ESAAALVIYL PEVAPVYFPA
CC	LEKILELLYE HEKDLVWKMR HEVQEHFPEA LARLLLVTKW NKHEDVAQML YLLCSWPELP
CC	VLSALELLDF SFPDCYVGSF AIKSLRKLTD DELFQYLLQL VQVLKYESYL DCELTKFLLG
CC	RALANRKIGH FLFWHLRSEM HVPSVALRFG LIMEAYCRGS THHMKVLMKQ GEALSKLKAL
CC	NDFVKVSSQK TTKPQTKEMM HMCMRQETYM EALSHLQSPL DPSTLLEEVC VEQCTFMDSK
CC	MKPLWIMYSS EEAGSAGNVG IIFKNGDDLR QDMLTLQMIQ LMDVLWKQEG LDLRMTPYGC
CC	LPTGDRTGLI EVVLHSDTIA NIQLNAAFNK DALLNWLKSK NPGEALDRAI EEFTLSCAGY
CC	CVATYVLGIG DRHSDNIMIR ESGQLFHIDF GHFLGNVPFI LTYDFVHVIQ QGKTNNSEKF
CC	ERFRGYCERA YTILRRHGLL FLHLFALMRA AGLPELSCSK DIQYLKDSLA LGKTEEEALK
CC	HFRVKFNEAL RESW
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES QGGDRVKKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAH
CC	ATOM   -----VKKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAH
CC	            *********************************************
CC	SEQRES RQQLGWVEWLQYSFPLQLEPSARGWRAGLLRVSNRALLVNVKFEGSEESF
CC	ATOM   RQQLGWVEWLQYSFPLQLEP-------------NRALLVNVKFEGSEESF
CC	       ********************             *****************
CC	SEQRES TFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYALQVNGRHEYLYGN
CC	ATOM   TFQVSTKDMPLALMACALRKKATVFRQ----QPEEYALQVNGRHEYLYGN
CC	       ***************************    *******************
CC	SEQRES YPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRAKP
CC	ATOM   YPLCHFQYICSCLHS-LTPHLTMVHSSSILAMRDEQSN------------
CC	       *************** **********************            
CC	SEQRES PPIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEM
CC	ATOM   -------------WSLEQPFSI-LIEGRKVNAD--MKLVVQAGLFHGNEM
CC	                    ********* **********  ***************
CC	SEQRES LCKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKK
CC	ATOM   LCKTVSSSE---CSEPVW----EFDISVCDLPRMARLCFALYAV------
CC	       *********   ******    **********************      
CC	SEQRES ARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELL
CC	ATOM   -----------DCPIAWANLMLFDYKDQLKTGERCLYMWPSV-------L
CC	                  *******************************       *
CC	SEQRES NPAGTVRGNPNTESAAALVIYLPEVAPHPVYFPALEKILELGRHGERGRI
CC	ATOM   NPAGTVRGNPNTESAAALVIYLPEVA--PVYFPALEKILEL---------
CC	       **************************  *************         
CC	SEQRES TEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQEHFPEALARLLLVT
CC	ATOM   -------------------LYEHEKDLVWKMRHEVQEHFPEALARLLLVT
CC	                          *******************************
CC	SEQRES KWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKL
CC	ATOM   KWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKL
CC	       **************************************************
CC	SEQRES TDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRS
CC	ATOM   TDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRS
CC	       **************************************************
CC	SEQRES EMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSS
CC	ATOM   EMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSS
CC	       **************************************************
CC	SEQRES QKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMD
CC	ATOM   QKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMD
CC	       **************************************************
CC	SEQRES SKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQ
CC	ATOM   SKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQ
CC	       **************************************************
CC	SEQRES EGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKD
CC	ATOM   EGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLN-------AAFNKD
CC	       *************************************       ******
CC	SEQRES ALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRE
CC	ATOM   ALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRE
CC	       **************************************************
CC	SEQRES SGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKF
CC	ATOM   SGQLFHIDFGHFLGN-----------VPFILTYDFVHVIQQGKTNNSEKF
CC	       ***************           ************************
CC	SEQRES ERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLA
CC	ATOM   ERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLA
CC	       **************************************************
CC	SEQRES LGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
CC	ATOM   LGKTEEEALKHFRVKFNEALRESW-----------------
CC	       ************************                 
SQ	SEQUENCE	941 AA;      MW;         CN;
	QGGDRVKKLI NSQISLLIGK GLHEFDSLRD PEVNDFRTKM RQFCEEAAAH RQQLGWVEWL
	QYSFPLQLEP SARGWRAGLL RVSNRALLVN VKFEGSEESF TFQVSTKDMP LALMACALRK
	KATVFRQPLV EQPEEYALQV NGRHEYLYGN YPLCHFQYIC SCLHSGLTPH LTMVHSSSIL
	AMRDEQSNPA PQVQKPRAKP PPIPAKKPSS VSLWSLEQPF SIELIEGRKV NADERMKLVV
	QAGLFHGNEM LCKTVSSSEV NVCSEPVWKQ RLEFDISVCD LPRMARLCFA LYAVVEKAKK
	ARSTKKKSKK ADCPIAWANL MLFDYKDQLK TGERCLYMWP SVPDEKGELL NPAGTVRGNP
	NTESAAALVI YLPEVAPHPV YFPALEKILE LGRHGERGRI TEEEQLQLRE ILERRGSGEL
	YEHEKDLVWK MRHEVQEHFP EALARLLLVT KWNKHEDVAQ MLYLLCSWPE LPVLSALELL
	DFSFPDCYVG SFAIKSLRKL TDDELFQYLL QLVQVLKYES YLDCELTKFL LGRALANRKI
	GHFLFWHLRS EMHVPSVALR FGLIMEAYCR GSTHHMKVLM KQGEALSKLK ALNDFVKVSS
	QKTTKPQTKE MMHMCMRQET YMEALSHLQS PLDPSTLLEE VCVEQCTFMD SKMKPLWIMY
	SSEEAGSAGN VGIIFKNGDD LRQDMLTLQM IQLMDVLWKQ EGLDLRMTPY GCLPTGDRTG
	LIEVVLHSDT IANIQLNKSN MAATAAFNKD ALLNWLKSKN PGEALDRAIE EFTLSCAGYC
	VATYVLGIGD RHSDNIMIRE SGQLFHIDFG HFLGNFKTKF GINRERVPFI LTYDFVHVIQ
	QGKTNNSEKF ERFRGYCERA YTILRRHGLL FLHLFALMRA AGLPELSCSK DIQYLKDSLA
	LGKTEEEALK HFRVKFNEAL RESWKTKVNW LAHNVSKDNR Q
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