ID	5LWNA	STANDARD;	PRT;	294	AA.
DT	CONVERTED FROM PDB (SEQRES) 5LWN
DE	Tyrosine-protein kinase JAK3
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.600
CC	R-Factor	0.169
FT	#HET	19	 828 	LEU	A	8	1208 	79R	A	B	4
FT	#HET	19	 828 	LEU	A	9	1209 	79S	A	B	4
FT	#HET	20	 829 	GLY	A	8	1208 	79R	A	B	2
FT	#HET	20	 829 	GLY	A	9	1209 	79S	A	B	2
FT	#HET	21	 830 	LYS	A	3	1203 	EDO	A	B	1
FT	#HET	22	 831 	GLY	A	3	1203 	EDO	A	B	2
FT	#HET	25	 834 	GLY	A	3	1203 	EDO	A	B	2
FT	#HET	26	 835 	SER	A	3	1203 	EDO	A	B	1
FT	#HET	27	 836 	VAL	A	3	1203 	EDO	A	S	3
FT	#HET	44	 853 	ALA	A	8	1208 	79R	A	S	3
FT	#HET	44	 853 	ALA	A	9	1209 	79S	A	S	3
FT	#HET	46	 855 	LYS	A	3	1203 	EDO	A	S	5
FT	#HET	54	 863 	ASP	A	2	1202 	EDO	A	A	9
FT	#HET	57	 866 	ARG	A	2	1202 	EDO	A	S	2
FT	#HET	58	 867 	ASP	A	2	1202 	EDO	A	S	4
FT	#HET	75	 884 	VAL	A	8	1208 	79R	A	S	1
FT	#HET	94	 903 	GLU	A	8	1208 	79R	A	B	4
FT	#HET	94	 903 	GLU	A	9	1209 	79S	A	B	4
FT	#HET	95	 904 	TYR	A	8	1208 	79R	A	A	5
FT	#HET	95	 904 	TYR	A	9	1209 	79S	A	A	5
FT	#HET	96	 905 	LEU	A	8	1208 	79R	A	B	6
FT	#HET	96	 905 	LEU	A	9	1209 	79S	A	B	5
FT	#HET	100	 909 	CYS	A	8	1208 	79R	A	S	9
FT	#HET	100	 909 	CYS	A	9	1209 	79S	A	S	9
FT	#HET	102	 911 	ARG	A	7	1207 	EDO	A	S	5
FT	#HET	102	 911 	ARG	A	8	1208 	79R	A	S	4
FT	#HET	102	 911 	ARG	A	9	1209 	79S	A	S	4
FT	#HET	103	 912 	ASP	A	8	1208 	79R	A	S	4
FT	#HET	103	 912 	ASP	A	9	1209 	79S	A	S	8
FT	#HET	115	 924 	SER	A	4	1204 	EDO	A	A	6
FT	#HET	116	 925 	ARG	A	4	1204 	EDO	A	A	9
FT	#HET	119	 928 	LEU	A	4	1204 	EDO	A	S	1
FT	#HET	144	 953 	ARG	A	8	1208 	79R	A	A	9
FT	#HET	144	 953 	ARG	A	9	1209 	79S	A	A	8
FT	#HET	145	 954 	ASN	A	8	1208 	79R	A	B	1
FT	#HET	145	 954 	ASN	A	9	1209 	79S	A	B	1
FT	#HET	147	 956 	LEU	A	8	1208 	79R	A	S	12
FT	#HET	147	 956 	LEU	A	9	1209 	79S	A	S	12
FT	#HET	158	 967 	ASP	A	8	1208 	79R	A	S	1
FT	#HET	170	 979 	ASP	A	6	1206 	EDO	A	A	2
FT	#HET	171	 980 	TYR	A	6	1206 	EDO	A	S	2
FT	#HET	183	 992 	PHE	A	1	1201 	PHU	A	S	1
FT	#HET	184	 993 	TRP	A	7	1207 	EDO	A	S	2
FT	#HET	187	 996 	PRO	A	5	1205 	EDO	A	S	4
FT	#HET	196	1005 	SER	A	6	1206 	EDO	A	S	1
FT	#HET	198	1007 	GLN	A	6	1206 	EDO	A	S	7
FT	#HET	202	1011 	TRP	A	1	1201 	PHU	A	S	3
FT	#HET	210	1019 	GLU	A	7	1207 	EDO	A	S	5
FT	#HET	215	1024 	CYS	A	7	1207 	EDO	A	A	7
FT	#HET	216	1025 	ASP	A	7	1207 	EDO	A	B	1
FT	#HET	220	1029 	SER	A	7	1207 	EDO	A	A	2
FT	#HET	221	1030 	PRO	A	1	1201 	PHU	A	B	1
FT	#HET	221	1030 	PRO	A	7	1207 	EDO	A	S	2
FT	#HET	225	1034 	PHE	A	1	1201 	PHU	A	A	2
FT	#HET	228	1037 	MET	A	1	1201 	PHU	A	S	2
FT	#HET	241	1050 	LEU	A	1	1201 	PHU	A	S	1
FT	#HET	245	1054 	LEU	A	1	1201 	PHU	A	S	2
FT	#HET	245	1054 	LEU	A	5	1205 	EDO	A	B	4
FT	#HET	246	1055 	GLU	A	5	1205 	EDO	A	A	7
FT	#HET	250	1059 	ARG	A	1	1201 	PHU	A	A	4
FT	#HET	250	1059 	ARG	A	5	1205 	EDO	A	S	2
FT	#HET	251	1060 	LEU	A	1	1201 	PHU	A	A	13
FT	#HET	269	1078 	TRP	A	1	1201 	PHU	A	S	6
FT	#HET	271	1080 	PRO	A	5	1205 	EDO	A	A	4
FT	#HET	273	1082 	PRO	A	6	1206 	EDO	A	S	1
FT	#HET	274	1083 	GLN	A	6	1206 	EDO	A	S	5
FT	#HET	290	1099 	TRP	A	4	1204 	EDO	A	S	5
FT	#HET	294	1103 	ARG	A	4	1204 	EDO	A	S	1
FT	DISORDER	1	4
CC	SEQUENCE	290 AA (ATOM);
CC	PTIFEERHLK YISQLGKGNF GSVELCRYDP LGDNTGALVA VKQLQHSGPD QQRDFQREIQ
CC	ILKALHSDFI VKYRGVSYGP GRQSLRLVME YLPSGCLRDF LQRHRARLDA SRLLLYSSQI
CC	CKGMEYLGSR RCVHRALAAR NILVESEAHV KIADFGLAKL LPLDKDYYVV REPGQSPIFW
CC	YAPESLSDNI FSRQSDVWSF GVVLYELFTY CDKSCSPSAE FLRMMGSERD VPALSRLLEL
CC	LEEGQRLPAP PACPAEVHEL MKLCWAPSPQ DRPSFSALGP QLDMLWSGSR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES SMQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQH
CC	ATOM   ----PTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQH
CC	           **********************************************
CC	SEQRES SGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGC
CC	ATOM   SGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGC
CC	       **************************************************
CC	SEQRES LRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRALAARNILVES
CC	ATOM   LRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRALAARNILVES
CC	       **************************************************
CC	SEQRES EAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSD
CC	ATOM   EAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSD
CC	       **************************************************
CC	SEQRES VWSFGVVLYELFTYCDKSCSPSAEFLRMMGSERDVPALSRLLELLEEGQR
CC	ATOM   VWSFGVVLYELFTYCDKSCSPSAEFLRMMGSERDVPALSRLLELLEEGQR
CC	       **************************************************
CC	SEQRES LPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSR
CC	ATOM   LPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSR
CC	       ********************************************
SQ	SEQUENCE	294 AA;      MW;         CN;
	SMQDPTIFEE RHLKYISQLG KGNFGSVELC RYDPLGDNTG ALVAVKQLQH SGPDQQRDFQ
	REIQILKALH SDFIVKYRGV SYGPGRQSLR LVMEYLPSGC LRDFLQRHRA RLDASRLLLY
	SSQICKGMEY LGSRRCVHRA LAARNILVES EAHVKIADFG LAKLLPLDKD YYVVREPGQS
	PIFWYAPESL SDNIFSRQSD VWSFGVVLYE LFTYCDKSCS PSAEFLRMMG SERDVPALSR
	LLELLEEGQR LPAPPACPAE VHELMKLCWA PSPQDRPSFS ALGPQLDMLW SGSR
//