ID	5LWMA	STANDARD;	PRT;	294	AA.
DT	CONVERTED FROM PDB (SEQRES) 5LWM
DE	Tyrosine-protein kinase JAK3
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.550
CC	R-Factor	0.166
FT	#HET	19	 828 	LEU	A	1	1201 	79T	A	A	4
FT	#HET	20	 829 	GLY	A	1	1201 	79T	A	B	1
FT	#HET	22	 831 	GLY	A	3	1203 	EDO	A	B	2
FT	#HET	25	 834 	GLY	A	3	1203 	EDO	A	B	4
FT	#HET	26	 835 	SER	A	3	1203 	EDO	A	B	2
FT	#HET	27	 836 	VAL	A	1	1201 	79T	A	S	2
FT	#HET	27	 836 	VAL	A	3	1203 	EDO	A	S	2
FT	#HET	44	 853 	ALA	A	1	1201 	79T	A	S	3
FT	#HET	46	 855 	LYS	A	3	1203 	EDO	A	S	2
FT	#HET	54	 863 	ASP	A	4	1204 	EDO	A	A	7
FT	#HET	57	 866 	ARG	A	4	1204 	EDO	A	S	1
FT	#HET	58	 867 	ASP	A	4	1204 	EDO	A	S	6
FT	#HET	94	 903 	GLU	A	1	1201 	79T	A	B	5
FT	#HET	95	 904 	TYR	A	1	1201 	79T	A	A	5
FT	#HET	96	 905 	LEU	A	1	1201 	79T	A	B	6
FT	#HET	100	 909 	CYS	A	1	1201 	79T	A	S	9
FT	#HET	102	 911 	ARG	A	1	1201 	79T	A	S	4
FT	#HET	103	 912 	ASP	A	1	1201 	79T	A	S	7
FT	#HET	115	 924 	SER	A	7	1207 	EDO	A	A	8
FT	#HET	116	 925 	ARG	A	7	1207 	EDO	A	A	8
FT	#HET	119	 928 	LEU	A	7	1207 	EDO	A	S	2
FT	#HET	129	 938 	GLU	A	6	1206 	EDO	A	A	3
FT	#HET	130	 939 	TYR	A	6	1206 	EDO	A	A	5
FT	#HET	133	 942 	SER	A	6	1206 	EDO	A	S	4
FT	#HET	134	 943 	ARG	A	6	1206 	EDO	A	S	1
FT	#HET	144	 953 	ARG	A	1	1201 	79T	A	A	7
FT	#HET	145	 954 	ASN	A	1	1201 	79T	A	S	1
FT	#HET	147	 956 	LEU	A	1	1201 	79T	A	S	12
FT	#HET	158	 967 	ASP	A	1	1201 	79T	A	S	1
FT	#HET	163	 972 	LYS	A	8	1208 	EDO	A	S	2
FT	#HET	172	 981 	TYR	A	8	1208 	EDO	A	A	5
FT	#HET	173	 982 	VAL	A	8	1208 	EDO	A	B	6
FT	#HET	183	 992 	PHE	A	2	1202 	PHU	A	S	1
FT	#HET	187	 996 	PRO	A	5	1205 	EDO	A	S	4
FT	#HET	202	1011 	TRP	A	2	1202 	PHU	A	S	3
FT	#HET	221	1030 	PRO	A	2	1202 	PHU	A	B	1
FT	#HET	225	1034 	PHE	A	2	1202 	PHU	A	A	2
FT	#HET	228	1037 	MET	A	2	1202 	PHU	A	S	2
FT	#HET	245	1054 	LEU	A	2	1202 	PHU	A	S	2
FT	#HET	245	1054 	LEU	A	5	1205 	EDO	A	B	4
FT	#HET	246	1055 	GLU	A	5	1205 	EDO	A	A	7
FT	#HET	250	1059 	ARG	A	2	1202 	PHU	A	A	4
FT	#HET	250	1059 	ARG	A	5	1205 	EDO	A	S	3
FT	#HET	251	1060 	LEU	A	2	1202 	PHU	A	A	13
FT	#HET	269	1078 	TRP	A	2	1202 	PHU	A	S	7
FT	#HET	271	1080 	PRO	A	5	1205 	EDO	A	A	5
FT	#HET	290	1099 	TRP	A	7	1207 	EDO	A	S	8
FT	#HET	294	1103 	ARG	A	7	1207 	EDO	A	S	1
FT	DISORDER	1	4
CC	SEQUENCE	290 AA (ATOM);
CC	PTIFEERHLK YISQLGKGNF GSVELCRYDP LGDNTGALVA VKQLQHSGPD QQRDFQREIQ
CC	ILKALHSDFI VKYRGVSYGP GRQSLRLVME YLPSGCLRDF LQRHRARLDA SRLLLYSSQI
CC	CKGMEYLGSR RCVHRALAAR NILVESEAHV KIADFGLAKL LPLDKDYYVV REPGQSPIFW
CC	YAPESLSDNI FSRQSDVWSF GVVLYELFTY CDKSCSPSAE FLRMMGSERD VPALSRLLEL
CC	LEEGQRLPAP PACPAEVHEL MKLCWAPSPQ DRPSFSALGP QLDMLWSGSR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES SMQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQH
CC	ATOM   ----PTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQH
CC	           **********************************************
CC	SEQRES SGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGC
CC	ATOM   SGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGC
CC	       **************************************************
CC	SEQRES LRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRALAARNILVES
CC	ATOM   LRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRALAARNILVES
CC	       **************************************************
CC	SEQRES EAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSD
CC	ATOM   EAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSD
CC	       **************************************************
CC	SEQRES VWSFGVVLYELFTYCDKSCSPSAEFLRMMGSERDVPALSRLLELLEEGQR
CC	ATOM   VWSFGVVLYELFTYCDKSCSPSAEFLRMMGSERDVPALSRLLELLEEGQR
CC	       **************************************************
CC	SEQRES LPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSR
CC	ATOM   LPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSR
CC	       ********************************************
SQ	SEQUENCE	294 AA;      MW;         CN;
	SMQDPTIFEE RHLKYISQLG KGNFGSVELC RYDPLGDNTG ALVAVKQLQH SGPDQQRDFQ
	REIQILKALH SDFIVKYRGV SYGPGRQSLR LVMEYLPSGC LRDFLQRHRA RLDASRLLLY
	SSQICKGMEY LGSRRCVHRA LAARNILVES EAHVKIADFG LAKLLPLDKD YYVVREPGQS
	PIFWYAPESL SDNIFSRQSD VWSFGVVLYE LFTYCDKSCS PSAEFLRMMG SERDVPALSR
	LLELLEEGQR LPAPPACPAE VHELMKLCWA PSPQDRPSFS ALGPQLDMLW SGSR
//