ID	5F8PA	STANDARD;	PRT;	476	AA.
DT	CONVERTED FROM PDB (SEQRES) 5F8P
DE	Alpha-ketoglutarate-dependent dioxygenase FTO
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.200
CC	R-Factor	0.190
FT	#HET	57	  83 	VAL	A	2	602 	FIJ	A	S	1
FT	#HET	59	  85 	ILE	A	2	602 	FIJ	A	S	2
FT	#HET	64	  90 	LEU	A	2	602 	FIJ	A	S	1
FT	#HET	66	  92 	THR	A	2	602 	FIJ	A	A	5
FT	#HET	67	  93 	PRO	A	2	602 	FIJ	A	S	1
FT	#HET	70	  96 	ARG	A	3	603 	AKG	A	S	3
FT	#HET	82	 108 	TYR	A	2	602 	FIJ	A	S	4
FT	#HET	82	 108 	TYR	A	3	603 	AKG	A	S	5
FT	#HET	83	 109 	LEU	A	2	602 	FIJ	A	S	6
FT	#HET	86	 112 	ARG	A	1	601 	SO4	A	S	9
FT	#HET	179	 205 	ASN	A	3	603 	AKG	A	S	4
FT	#HET	203	 229 	SER	A	2	602 	FIJ	A	A	9
FT	#HET	204	 230 	TRP	A	2	602 	FIJ	A	B	4
FT	#HET	205	 231 	HIS	A	2	602 	FIJ	A	S	13
FT	#HET	205	 231 	HIS	A	3	603 	AKG	A	S	2
FT	#HET	205	 231 	HIS	A	4	604 	FE2	A	S	2
FT	#HET	206	 232 	HIS	A	2	602 	FIJ	A	B	1
FT	#HET	207	 233 	ASP	A	4	604 	FE2	A	S	3
FT	#HET	208	 234 	GLU	A	2	602 	FIJ	A	S	4
FT	#HET	218	 244 	VAL	A	3	603 	AKG	A	S	1
FT	#HET	269	 295 	TYR	A	3	603 	AKG	A	S	5
FT	#HET	281	 307 	HIS	A	4	604 	FE2	A	S	3
FT	#HET	283	 309 	VAL	A	3	603 	AKG	A	S	5
FT	#HET	290	 316 	ARG	A	3	603 	AKG	A	S	8
FT	#HET	292	 318 	SER	A	3	603 	AKG	A	S	3
FT	#HET	294	 320 	THR	A	3	603 	AKG	A	S	3
FT	#HET	296	 322 	ARG	A	3	603 	AKG	A	S	1
FT	#HET	299	 325 	GLU	A	1	601 	SO4	A	S	1
FT	#HET	302	 328 	THR	A	1	601 	SO4	A	A	7
FT	#HET	303	 329 	GLY	A	1	601 	SO4	A	B	1
FT	DISORDER	96	101
FT	DISORDER	136	162
FT	DISORDER	225	235
CC	SEQUENCE	432 AA (ATOM);
CC	LESHMTPKDD EFYQQWQLKY PKLILREASS VSEELHKEVQ EAFLTLHKHG CLFRDLVRIQ
CC	GKDLLTPVSR ILIGNPGCTY KYLNTRLFTV PWPVKTEAEI AAACETFLKL NDYLQIETIQ
CC	ALEELAAKED EVDIKSRAAY NVTLLNFMDP QKMPYLKEEP YFGMGKMAVS WHHDENLVDR
CC	SAVAVYSYSC ELEGRDPDIW HVGFKISWDI ETPGLAIPLH QGDCYFMLDD LNATHQHCVL
CC	AGSQPRFSST HRVAECSTGT LDYILQRCQL ALQNVCDDVD NDDVSLKSFE PAVLKQGEEI
CC	HNEVEFEWLR QFWFQGNRYR KCTDWWCQPM AQLEALWKKM EGVTNAVLHE VKREGLPVEQ
CC	RNEILTAILA SLTARQNLRR EWHARCQSRI ARTLPADQKP ECRPYWEKDD ASMPLPFDLT
CC	DIVSELRGQL LE
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES LESHMTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHG
CC	ATOM   LESHMTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHG
CC	       **************************************************
CC	SEQRES CLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIK
CC	ATOM   CLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVK-----
CC	       *********************************************     
CC	SEQRES HTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADF
CC	ATOM   -TEAEIAAACETFLKLNDYLQIETIQALEELAAKE---------------
CC	        **********************************               
CC	SEQRES PRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKM
CC	ATOM   ------------DEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKM
CC	                   **************************************
CC	SEQRES AVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKI
CC	ATOM   AVSWHHDENLVDRSAVAVYSYSCE-----------LEGRDPDIWHVGFKI
CC	       ************************           ***************
CC	SEQRES SWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAEC
CC	ATOM   SWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAEC
CC	       **************************************************
CC	SEQRES STGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEF
CC	ATOM   STGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEF
CC	       **************************************************
CC	SEQRES EWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGL
CC	ATOM   EWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGL
CC	       **************************************************
CC	SEQRES PVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYW
CC	ATOM   PVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYW
CC	       **************************************************
CC	SEQRES EKDDASMPLPFDLTDIVSELRGQLLE
CC	ATOM   EKDDASMPLPFDLTDIVSELRGQLLE
CC	       **************************
SQ	SEQUENCE	476 AA;      MW;         CN;
	LESHMTPKDD EFYQQWQLKY PKLILREASS VSEELHKEVQ EAFLTLHKHG CLFRDLVRIQ
	GKDLLTPVSR ILIGNPGCTY KYLNTRLFTV PWPVKGSNIK HTEAEIAAAC ETFLKLNDYL
	QIETIQALEE LAAKEKANED AVPLCMSADF PRVGMGSSYN GQDEVDIKSR AAYNVTLLNF
	MDPQKMPYLK EEPYFGMGKM AVSWHHDENL VDRSAVAVYS YSCEGPEEES EDDSHLEGRD
	PDIWHVGFKI SWDIETPGLA IPLHQGDCYF MLDDLNATHQ HCVLAGSQPR FSSTHRVAEC
	STGTLDYILQ RCQLALQNVC DDVDNDDVSL KSFEPAVLKQ GEEIHNEVEF EWLRQFWFQG
	NRYRKCTDWW CQPMAQLEAL WKKMEGVTNA VLHEVKREGL PVEQRNEILT AILASLTARQ
	NLRREWHARC QSRIARTLPA DQKPECRPYW EKDDASMPLP FDLTDIVSEL RGQLLE
//