ID	5A80A	STANDARD;	PRT;	381	AA.
DT	CONVERTED FROM PDB (SEQRES) 5A80
DE	LYSINE-SPECIFIC DEMETHYLASE 4A
OS	HOMO SAPIENS
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.280
CC	R-Factor	0.193
FT	#SUB	28	   6 	GLU	A	134	 112 	SER	B	Protein	S	2
FT	#SUB	273	 251 	LYS	A	38	  16 	THR	B	Protein	B	1
FT	#SUB	273	 251 	LYS	A	40	  18 	TYR	B	Protein	A	7
FT	#SUB	274	 252 	LYS	A	37	  15 	MET	B	Protein	B	3
FT	#SUB	274	 252 	LYS	A	38	  16 	THR	B	Protein	B	5
FT	#SUB	274	 252 	LYS	A	59	  37 	GLN	B	Protein	S	1
FT	#SUB	275	 253 	TYR	A	31	   9 	ASN	B	Protein	S	5
FT	#SUB	275	 253 	TYR	A	37	  15 	MET	B	Protein	S	2
FT	#HET	154	 132 	TYR	A	3	1357 	9CJ	A	S	5
FT	#HET	157	 135 	ASP	A	3	1357 	9CJ	A	S	6
FT	#HET	172	 150 	ILE	A	8	1362 	EDO	A	B	3
FT	#HET	173	 151 	GLY	A	8	1362 	EDO	A	B	4
FT	#HET	174	 152 	ARG	A	8	1362 	EDO	A	B	4
FT	#HET	175	 153 	LEU	A	8	1362 	EDO	A	A	4
FT	#HET	192	 170 	GLY	A	5	1359 	EDO	A	B	4
FT	#HET	194	 172 	ASN	A	8	1362 	EDO	A	B	1
FT	#HET	197	 175 	TYR	A	5	1359 	EDO	A	S	2
FT	#HET	199	 177 	TYR	A	3	1357 	9CJ	A	S	4
FT	#HET	199	 177 	TYR	A	5	1359 	EDO	A	S	2
FT	#HET	207	 185 	PHE	A	3	1357 	9CJ	A	S	18
FT	#HET	210	 188 	HIS	A	2	1356 	MN	A	S	3
FT	#HET	210	 188 	HIS	A	3	1357 	9CJ	A	S	16
FT	#HET	210	 188 	HIS	A	6	1360 	EDO	A	B	2
FT	#HET	211	 189 	THR	A	6	1360 	EDO	A	A	6
FT	#HET	212	 190 	GLU	A	2	1356 	MN	A	S	3
FT	#HET	212	 190 	GLU	A	3	1357 	9CJ	A	S	7
FT	#HET	212	 190 	GLU	A	5	1359 	EDO	A	S	2
FT	#HET	218	 196 	SER	A	5	1359 	EDO	A	S	2
FT	#HET	220	 198 	ASN	A	3	1357 	9CJ	A	S	1
FT	#HET	228	 206 	LYS	A	3	1357 	9CJ	A	S	4
FT	#HET	230	 208 	TRP	A	3	1357 	9CJ	A	S	2
FT	#HET	246	 224 	LYS	A	7	1361 	EDO	A	S	2
FT	#HET	249	 227 	PHE	A	1	1355 	SO4	A	A	5
FT	#HET	250	 228 	PRO	A	1	1355 	SO4	A	A	5
FT	#HET	251	 229 	GLY	A	1	1355 	SO4	A	B	8
FT	#HET	252	 230 	SER	A	1	1355 	SO4	A	A	6
FT	#HET	253	 231 	ALA	A	7	1361 	EDO	A	B	5
FT	#HET	256	 234 	CYS	A	4	1358 	ZN	A	S	2
FT	#HET	256	 234 	CYS	A	7	1361 	EDO	A	B	3
FT	#HET	257	 235 	GLU	A	7	1361 	EDO	A	B	8
FT	#HET	258	 236 	ALA	A	7	1361 	EDO	A	B	7
FT	#HET	259	 237 	PHE	A	7	1361 	EDO	A	A	9
FT	#HET	260	 238 	LEU	A	6	1360 	EDO	A	B	1
FT	#HET	261	 239 	ARG	A	6	1360 	EDO	A	A	11
FT	#HET	262	 240 	HIS	A	3	1357 	9CJ	A	B	4
FT	#HET	262	 240 	HIS	A	4	1358 	ZN	A	S	3
FT	#HET	263	 241 	LYS	A	3	1357 	9CJ	A	S	6
FT	#HET	274	 252 	LYS	A	16	1360 	EDO	B	A	4
FT	#HET	297	 275 	TYR	A	6	1360 	EDO	A	S	8
FT	#HET	298	 276 	HIS	A	2	1356 	MN	A	S	3
FT	#HET	298	 276 	HIS	A	3	1357 	9CJ	A	S	4
FT	#HET	310	 288 	SER	A	5	1359 	EDO	A	A	7
FT	#HET	311	 289 	THR	A	5	1359 	EDO	A	B	2
FT	#HET	312	 290 	ASN	A	5	1359 	EDO	A	S	3
FT	#HET	312	 290 	ASN	A	8	1362 	EDO	A	B	2
FT	#HET	313	 291 	PHE	A	8	1362 	EDO	A	S	1
FT	#HET	326	 304 	VAL	A	6	1360 	EDO	A	B	1
FT	#HET	328	 306 	CYS	A	4	1358 	ZN	A	A	3
FT	#HET	329	 307 	SER	A	4	1358 	ZN	A	B	1
FT	#HET	330	 308 	CYS	A	4	1358 	ZN	A	A	3
FT	#HET	337	 315 	ILE	A	9	1363 	EDO	A	B	1
FT	#HET	338	 316 	SER	A	9	1363 	EDO	A	A	5
FT	#HET	339	 317 	MET	A	9	1363 	EDO	A	A	7
FT	#HET	340	 318 	ASP	A	9	1363 	EDO	A	S	1
FT	#HET	354	 332 	TRP	A	9	1363 	EDO	A	S	2
FT	DISORDER	1	25
FT	DISORDER	377	381
CC	Miss-BB	1
CC	Miss-SC	1
CC	SEQUENCE	351 AA (ATOM);
CC	ESETLNPSAR IMTFYPTMEE FRNFSRYIAY IESQGAHRAG LAKVVPPKEW KPRASYDDID
CC	DLVIPAPIQQ LVTGQSGLFT QYNIQKKAMT VREFRKIANS DKYCTPRYSE FEELERKYWK
CC	NLTFNPPIYG ADVNGTLYEK HVDEWNIGRL RTILDLVEKE SGITIEGVNT PYLYFGMWKT
CC	SFAWHTEDMD LYSINYLHFG EPKSWYSVPP EHGKRLERLA KGFFPGSAQS CEAFLRHKMT
CC	LISPLMLKKY GIPFDKVTQE AGEFMITFPY GYHAGFNHGF NCAESTNFAT RRWIEYGKQA
CC	VLCSCRKDMV KISMDVFVRK FQPERYKLWK AGKDNTVIDH TLPTPEAAEF L
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MHHHHHHSSGVDLGTENLYFQSMASESETLNPSARIMTFYPTMEEFRNFS
CC	ATOM   -------------------------ESETLNPSARIMTFYPTMEEFRNFS
CC	                                *************************
CC	SEQRES RYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQ
CC	ATOM   RYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQ
CC	       **************************************************
CC	SEQRES SGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFN
CC	ATOM   SGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFN
CC	       **************************************************
CC	SEQRES PPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYF
CC	ATOM   PPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYF
CC	       **************************************************
CC	SEQRES GMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFP
CC	ATOM   GMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFP
CC	       **************************************************
CC	SEQRES GSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAG
CC	ATOM   GSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAG
CC	       **************************************************
CC	SEQRES FNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPER
CC	ATOM   FNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPER
CC	       **************************************************
CC	SEQRES YKLWKAGKDNTVIDHTLPTPEAAEFLKESEL
CC	ATOM   YKLWKAGKDNTVIDHTLPTPEAAEFL-----
CC	       **************************     
SQ	SEQUENCE	381 AA;      MW;         CN;
	MHHHHHHSSG VDLGTENLYF QSMASESETL NPSARIMTFY PTMEEFRNFS RYIAYIESQG
	AHRAGLAKVV PPKEWKPRAS YDDIDDLVIP APIQQLVTGQ SGLFTQYNIQ KKAMTVREFR
	KIANSDKYCT PRYSEFEELE RKYWKNLTFN PPIYGADVNG TLYEKHVDEW NIGRLRTILD
	LVEKESGITI EGVNTPYLYF GMWKTSFAWH TEDMDLYSIN YLHFGEPKSW YSVPPEHGKR
	LERLAKGFFP GSAQSCEAFL RHKMTLISPL MLKKYGIPFD KVTQEAGEFM ITFPYGYHAG
	FNHGFNCAES TNFATRRWIE YGKQAVLCSC RKDMVKISMD VFVRKFQPER YKLWKAGKDN
	TVIDHTLPTP EAAEFLKESE L
//
ID	5A80B	STANDARD;	PRT;	381	AA.
DT	CONVERTED FROM PDB (SEQRES) 5A80
DE	LYSINE-SPECIFIC DEMETHYLASE 4A
OS	HOMO SAPIENS
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.280
CC	R-Factor	0.193
FT	#SUB	31	   9 	ASN	B	275	 253 	TYR	A	Protein	S	5
FT	#SUB	37	  15 	MET	B	274	 252 	LYS	A	Protein	A	3
FT	#SUB	37	  15 	MET	B	275	 253 	TYR	A	Protein	S	2
FT	#SUB	38	  16 	THR	B	273	 251 	LYS	A	Protein	S	1
FT	#SUB	38	  16 	THR	B	274	 252 	LYS	A	Protein	B	5
FT	#SUB	40	  18 	TYR	B	273	 251 	LYS	A	Protein	S	7
FT	#SUB	59	  37 	GLN	B	274	 252 	LYS	A	Protein	S	1
FT	#SUB	134	 112 	SER	B	28	   6 	GLU	A	Protein	A	2
FT	#HET	38	  16 	THR	B	16	1360 	EDO	B	B	2
FT	#HET	39	  17 	PHE	B	16	1360 	EDO	B	A	8
FT	#HET	40	  18 	TYR	B	16	1360 	EDO	B	A	7
FT	#HET	105	  83 	THR	B	15	1359 	EDO	B	S	3
FT	#HET	108	  86 	ASN	B	12	1356 	9CJ	B	A	5
FT	#HET	120	  98 	ARG	B	18	1362 	EDO	B	S	4
FT	#HET	124	 102 	ASN	B	18	1362 	EDO	B	S	1
FT	#HET	154	 132 	TYR	B	12	1356 	9CJ	B	S	5
FT	#HET	157	 135 	ASP	B	12	1356 	9CJ	B	S	4
FT	#HET	192	 170 	GLY	B	14	1358 	EDO	B	B	6
FT	#HET	197	 175 	TYR	B	14	1358 	EDO	B	S	3
FT	#HET	199	 177 	TYR	B	12	1356 	9CJ	B	S	6
FT	#HET	199	 177 	TYR	B	14	1358 	EDO	B	S	2
FT	#HET	207	 185 	PHE	B	12	1356 	9CJ	B	S	21
FT	#HET	210	 188 	HIS	B	11	1355 	MN	B	S	3
FT	#HET	210	 188 	HIS	B	12	1356 	9CJ	B	S	13
FT	#HET	212	 190 	GLU	B	11	1355 	MN	B	S	3
FT	#HET	212	 190 	GLU	B	12	1356 	9CJ	B	S	7
FT	#HET	212	 190 	GLU	B	14	1358 	EDO	B	S	2
FT	#HET	218	 196 	SER	B	14	1358 	EDO	B	S	1
FT	#HET	220	 198 	ASN	B	12	1356 	9CJ	B	S	1
FT	#HET	228	 206 	LYS	B	12	1356 	9CJ	B	S	4
FT	#HET	230	 208 	TRP	B	12	1356 	9CJ	B	S	3
FT	#HET	242	 220 	GLU	B	17	1361 	EDO	B	S	1
FT	#HET	246	 224 	LYS	B	17	1361 	EDO	B	S	1
FT	#HET	249	 227 	PHE	B	10	1354 	SO4	B	A	6
FT	#HET	249	 227 	PHE	B	15	1359 	EDO	B	S	3
FT	#HET	250	 228 	PRO	B	10	1354 	SO4	B	A	5
FT	#HET	251	 229 	GLY	B	10	1354 	SO4	B	B	8
FT	#HET	252	 230 	SER	B	10	1354 	SO4	B	A	7
FT	#HET	252	 230 	SER	B	15	1359 	EDO	B	S	4
FT	#HET	256	 234 	CYS	B	13	1357 	ZN	B	S	2
FT	#HET	257	 235 	GLU	B	17	1361 	EDO	B	B	2
FT	#HET	258	 236 	ALA	B	17	1361 	EDO	B	A	8
FT	#HET	259	 237 	PHE	B	15	1359 	EDO	B	S	2
FT	#HET	259	 237 	PHE	B	17	1361 	EDO	B	A	5
FT	#HET	260	 238 	LEU	B	17	1361 	EDO	B	A	8
FT	#HET	262	 240 	HIS	B	12	1356 	9CJ	B	B	1
FT	#HET	262	 240 	HIS	B	13	1357 	ZN	B	S	3
FT	#HET	263	 241 	LYS	B	12	1356 	9CJ	B	S	4
FT	#HET	264	 242 	MET	B	15	1359 	EDO	B	B	1
FT	#HET	265	 243 	THR	B	15	1359 	EDO	B	S	3
FT	#HET	298	 276 	HIS	B	11	1355 	MN	B	S	3
FT	#HET	298	 276 	HIS	B	12	1356 	9CJ	B	S	4
FT	#HET	310	 288 	SER	B	14	1358 	EDO	B	A	3
FT	#HET	311	 289 	THR	B	14	1358 	EDO	B	B	1
FT	#HET	312	 290 	ASN	B	14	1358 	EDO	B	S	4
FT	#HET	328	 306 	CYS	B	13	1357 	ZN	B	A	3
FT	#HET	329	 307 	SER	B	13	1357 	ZN	B	B	1
FT	#HET	330	 308 	CYS	B	13	1357 	ZN	B	A	4
FT	DISORDER	1	30
FT	DISORDER	376	381
CC	SEQUENCE	345 AA (ATOM);
CC	NPSARIMTFY PTMEEFRNFS RYIAYIESQG AHRAGLAKVV PPKEWKPRAS YDDIDDLVIP
CC	APIQQLVTGQ SGLFTQYNIQ KKAMTVREFR KIANSDKYCT PRYSEFEELE RKYWKNLTFN
CC	PPIYGADVNG TLYEKHVDEW NIGRLRTILD LVEKESGITI EGVNTPYLYF GMWKTSFAWH
CC	TEDMDLYSIN YLHFGEPKSW YSVPPEHGKR LERLAKGFFP GSAQSCEAFL RHKMTLISPL
CC	MLKKYGIPFD KVTQEAGEFM ITFPYGYHAG FNHGFNCAES TNFATRRWIE YGKQAVLCSC
CC	RKDMVKISMD VFVRKFQPER YKLWKAGKDN TVIDHTLPTP EAAEF
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MHHHHHHSSGVDLGTENLYFQSMASESETLNPSARIMTFYPTMEEFRNFS
CC	ATOM   ------------------------------NPSARIMTFYPTMEEFRNFS
CC	                                     ********************
CC	SEQRES RYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQ
CC	ATOM   RYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQ
CC	       **************************************************
CC	SEQRES SGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFN
CC	ATOM   SGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFN
CC	       **************************************************
CC	SEQRES PPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYF
CC	ATOM   PPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYF
CC	       **************************************************
CC	SEQRES GMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFP
CC	ATOM   GMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFP
CC	       **************************************************
CC	SEQRES GSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAG
CC	ATOM   GSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAG
CC	       **************************************************
CC	SEQRES FNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPER
CC	ATOM   FNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPER
CC	       **************************************************
CC	SEQRES YKLWKAGKDNTVIDHTLPTPEAAEFLKESEL
CC	ATOM   YKLWKAGKDNTVIDHTLPTPEAAEF------
CC	       *************************      
SQ	SEQUENCE	381 AA;      MW;         CN;
	MHHHHHHSSG VDLGTENLYF QSMASESETL NPSARIMTFY PTMEEFRNFS RYIAYIESQG
	AHRAGLAKVV PPKEWKPRAS YDDIDDLVIP APIQQLVTGQ SGLFTQYNIQ KKAMTVREFR
	KIANSDKYCT PRYSEFEELE RKYWKNLTFN PPIYGADVNG TLYEKHVDEW NIGRLRTILD
	LVEKESGITI EGVNTPYLYF GMWKTSFAWH TEDMDLYSIN YLHFGEPKSW YSVPPEHGKR
	LERLAKGFFP GSAQSCEAFL RHKMTLISPL MLKKYGIPFD KVTQEAGEFM ITFPYGYHAG
	FNHGFNCAES TNFATRRWIE YGKQAVLCSC RKDMVKISMD VFVRKFQPER YKLWKAGKDN
	TVIDHTLPTP EAAEFLKESE L
//