ID	4UWHA	STANDARD;	PRT;	601	AA.
DT	CONVERTED FROM PDB (SEQRES) 4UWH
DE	PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3
OS	HOMO SAPIENS
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.930
CC	R-Factor	0.184
FT	#HET	161	 439 	GLU	A	2	1875 	NA	A	B	2
FT	#HET	166	 444 	GLN	A	2	1875 	NA	A	S	1
FT	#HET	334	 612 	PHE	A	3	1876 	JXM	A	S	8
FT	#HET	336	 614 	SER	A	3	1876 	JXM	A	S	2
FT	#HET	340	 618 	PRO	A	3	1876 	JXM	A	S	4
FT	#HET	356	 634 	ILE	A	3	1876 	JXM	A	S	6
FT	#HET	358	 636 	LYS	A	3	1876 	JXM	A	S	5
FT	#HET	381	 659 	ARG	A	1	1874 	NA	A	S	1
FT	#HET	388	 666 	LYS	A	1	1874 	NA	A	B	1
FT	#HET	389	 667 	LEU	A	1	1874 	NA	A	B	4
FT	#HET	392	 670 	TYR	A	3	1876 	JXM	A	S	8
FT	#HET	404	 682 	MET	A	3	1876 	JXM	A	S	4
FT	#HET	405	 683 	GLN	A	3	1876 	JXM	A	B	3
FT	#HET	406	 684 	PHE	A	3	1876 	JXM	A	A	7
FT	#HET	407	 685 	ILE	A	3	1876 	JXM	A	A	9
FT	#HET	409	 687 	SER	A	3	1876 	JXM	A	A	3
FT	#HET	472	 750 	LEU	A	3	1876 	JXM	A	S	2
FT	#HET	480	 758 	PHE	A	3	1876 	JXM	A	S	1
FT	#HET	482	 760 	ILE	A	3	1876 	JXM	A	S	11
FT	#HET	483	 761 	ASP	A	3	1876 	JXM	A	B	2
FT	DISORDER	1	6
FT	DISORDER	140	156
FT	DISORDER	174	191
FT	DISORDER	596	601
CC	SEQUENCE	554 AA (ATOM);
CC	DLKPNAATRD QLNIIVSYPP TKQLTYEEQD LVWKFRYYLT NQEKALTKFL KCVNWDLPQE
CC	AKQALELLGK WKPMDVEDSL ELLSSHYTNP TVRRYAVARL RQADDEDLLM YLLQLVQALK
CC	YENFDDIKNG LEPINSAEID SSQIITSPLP NLEQDLCTFL ISRACKNSTL ANYLYWYVIV
CC	ECEDQDTQQR DPKTHEMYLN VMRRFSQALL KGDKSVRVMR SLLAAQQTFV DRLVHLMKAV
CC	QRESGNRKKK NERLQALLGD NEKMNLSDVE LIPLPLEPQV KIRGIIPETA TLFKSALMPA
CC	QLFFKTEDGG KYPVIFKHGD DLRQDQLILQ IISLMDKLLR KENLDLKLTP YKVLATSTKH
CC	GFMQFIQSVP VAEVLDTEGS IQNFFRKYAP SENGPNGISA EVMDTYVKSC AGYCVITYIL
CC	GVGDRHLDNL LLTKTGKLFH IDFGYILGRD PKPLPPPMKL NKEMVEGMGG TQSEQYQEFR
CC	KQCYTAFLHL RRYSNLILNL FSLMVDANIP DIALEPDKTV KKVQDKFRLD LSDEEAVHYM
CC	QSLIDESVHA LFAA
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GAMSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEK
CC	ATOM   ------DLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEK
CC	             ********************************************
CC	SEQRES ALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRR
CC	ATOM   ALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRR
CC	       **************************************************
CC	SEQRES YAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKKDSQSSVSE
CC	ATOM   YAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEP-----------
CC	       ***************************************           
CC	SEQRES NVSNSGINSAEIDSSQIITSPLPSVSSPPPASKTKEVPDGENLEQDLCTF
CC	ATOM   ------INSAEIDSSQIITSPLP------------------NLEQDLCTF
CC	             *****************                  *********
CC	SEQRES LISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQAL
CC	ATOM   LISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQAL
CC	       **************************************************
CC	SEQRES LKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLG
CC	ATOM   LKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLG
CC	       **************************************************
CC	SEQRES DNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDG
CC	ATOM   DNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDG
CC	       **************************************************
CC	SEQRES GKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTK
CC	ATOM   GKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTK
CC	       **************************************************
CC	SEQRES HGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKS
CC	ATOM   HGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKS
CC	       **************************************************
CC	SEQRES CAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMK
CC	ATOM   CAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMK
CC	       **************************************************
CC	SEQRES LNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANI
CC	ATOM   LNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANI
CC	       **************************************************
CC	SEQRES PDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQI
CC	ATOM   PDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAA-----
CC	       *********************************************     
CC	SEQRES H
CC	ATOM   -
CC	        
SQ	SEQUENCE	601 AA;      MW;         CN;
	GAMSDHDLKP NAATRDQLNI IVSYPPTKQL TYEEQDLVWK FRYYLTNQEK ALTKFLKCVN
	WDLPQEAKQA LELLGKWKPM DVEDSLELLS SHYTNPTVRR YAVARLRQAD DEDLLMYLLQ
	LVQALKYENF DDIKNGLEPT KKDSQSSVSE NVSNSGINSA EIDSSQIITS PLPSVSSPPP
	ASKTKEVPDG ENLEQDLCTF LISRACKNST LANYLYWYVI VECEDQDTQQ RDPKTHEMYL
	NVMRRFSQAL LKGDKSVRVM RSLLAAQQTF VDRLVHLMKA VQRESGNRKK KNERLQALLG
	DNEKMNLSDV ELIPLPLEPQ VKIRGIIPET ATLFKSALMP AQLFFKTEDG GKYPVIFKHG
	DDLRQDQLIL QIISLMDKLL RKENLDLKLT PYKVLATSTK HGFMQFIQSV PVAEVLDTEG
	SIQNFFRKYA PSENGPNGIS AEVMDTYVKS CAGYCVITYI LGVGDRHLDN LLLTKTGKLF
	HIDFGYILGR DPKPLPPPMK LNKEMVEGMG GTQSEQYQEF RKQCYTAFLH LRRYSNLILN
	LFSLMVDANI PDIALEPDKT VKKVQDKFRL DLSDEEAVHY MQSLIDESVH ALFAAVVEQI
	H
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