ID	4R09A	STANDARD;	PRT;	811	AA.
DT	CONVERTED FROM PDB (SEQRES) 4R09
DE	Toll-like receptor 8
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.620
CC	R-Factor	0.220
FT	#SUB	160	 182 	TYR	A	605	 627 	ASP	B	Protein	S	8
FT	#SUB	161	 183 	PHE	A	605	 627 	ASP	B	Protein	S	1
FT	#SUB	162	 184 	ASN	A	605	 627 	ASP	B	Protein	A	3
FT	#SUB	162	 184 	ASN	A	606	 628 	ASP	B	Protein	S	3
FT	#SUB	162	 184 	ASN	A	607	 629 	ASN	B	Protein	S	9
FT	#SUB	163	 185 	LYS	A	605	 627 	ASP	B	Protein	A	3
FT	#SUB	239	 261 	PHE	A	552	 574 	THR	B	Protein	S	2
FT	#SUB	239	 261 	PHE	A	578	 600 	THR	B	Protein	S	2
FT	#SUB	239	 261 	PHE	A	579	 601 	ASP	B	Protein	S	2
FT	#SUB	240	 262 	ASN	A	549	 571 	ALA	B	Protein	S	1
FT	#SUB	240	 262 	ASN	A	550	 572 	GLY	B	Protein	S	2
FT	#SUB	240	 262 	ASN	A	551	 573 	VAL	B	Protein	S	4
FT	#SUB	240	 262 	ASN	A	552	 574 	THR	B	Protein	S	2
FT	#SUB	240	 262 	ASN	A	578	 600 	THR	B	Protein	S	5
FT	#SUB	241	 263 	ALA	A	608	 630 	ARG	B	Protein	B	1
FT	#SUB	242	 264 	PRO	A	576	 598 	THR	B	Protein	B	1
FT	#SUB	242	 264 	PRO	A	608	 630 	ARG	B	Protein	B	1
FT	#SUB	243	 265 	PHE	A	608	 630 	ARG	B	Protein	B	9
FT	#SUB	244	 266 	PRO	A	605	 627 	ASP	B	Protein	S	1
FT	#SUB	244	 266 	PRO	A	606	 628 	ASP	B	Protein	S	6
FT	#SUB	244	 266 	PRO	A	608	 630 	ARG	B	Protein	A	5
FT	#SUB	324	 346 	PHE	A	550	 572 	GLY	B	Protein	S	4
FT	#SUB	326	 348 	TYR	A	550	 572 	GLY	B	Protein	S	2
FT	#SUB	381	 403 	ILE	A	551	 573 	VAL	B	Protein	S	1
FT	#SUB	383	 405 	PHE	A	521	 543 	ASP	B	Protein	S	2
FT	#SUB	383	 405 	PHE	A	545	 567 	TYR	B	Protein	S	1
FT	#SUB	383	 405 	PHE	A	551	 573 	VAL	B	Protein	S	2
FT	#SUB	405	 427 	GLU	A	544	 566 	HIS	B	Protein	S	6
FT	#SUB	405	 427 	GLU	A	545	 567 	TYR	B	Protein	S	1
FT	#SUB	405	 427 	GLU	A	548	 570 	ILE	B	Protein	S	4
FT	#SUB	407	 429 	ARG	A	496	 518 	ALA	B	Protein	S	6
FT	#SUB	407	 429 	ARG	A	498	 520 	VAL	B	Protein	S	1
FT	#SUB	407	 429 	ARG	A	521	 543 	ASP	B	Protein	S	3
FT	#SUB	409	 431 	SER	A	472	 494 	PHE	B	Protein	S	3
FT	#SUB	436	 458 	ASP	A	603	 625 	ASN	B	Protein	B	1
FT	#SUB	436	 458 	ASP	A	631	 653 	HIS	B	Protein	S	1
FT	#SUB	438	 460 	GLU	A	600	 622 	ILE	B	Protein	S	3
FT	#SUB	438	 460 	GLU	A	603	 625 	ASN	B	Protein	B	1
FT	#SUB	468	 490 	LEU	A	519	 541 	ARG	B	Protein	B	1
FT	#SUB	468	 490 	LEU	A	544	 566 	HIS	B	Protein	S	1
FT	#SUB	469	 491 	ASN	A	519	 541 	ARG	B	Protein	B	3
FT	#SUB	470	 492 	SER	A	472	 494 	PHE	B	Protein	S	3
FT	#SUB	472	 494 	PHE	A	409	 431 	SER	B	Protein	S	3
FT	#SUB	472	 494 	PHE	A	470	 492 	SER	B	Protein	S	3
FT	#SUB	472	 494 	PHE	A	472	 494 	PHE	B	Protein	S	4
FT	#SUB	492	 514 	ALA	A	519	 541 	ARG	B	Protein	B	4
FT	#SUB	494	 516 	SER	A	494	 516 	SER	B	Protein	S	4
FT	#SUB	496	 518 	ALA	A	407	 429 	ARG	B	Protein	A	5
FT	#SUB	498	 520 	VAL	A	407	 429 	ARG	B	Protein	S	1
FT	#SUB	519	 541 	ARG	A	469	 491 	ASN	B	Protein	S	2
FT	#SUB	519	 541 	ARG	A	492	 514 	ALA	B	Protein	S	5
FT	#SUB	521	 543 	ASP	A	383	 405 	PHE	B	Protein	S	3
FT	#SUB	521	 543 	ASP	A	407	 429 	ARG	B	Protein	S	3
FT	#SUB	544	 566 	HIS	A	405	 427 	GLU	B	Protein	S	5
FT	#SUB	544	 566 	HIS	A	468	 490 	LEU	B	Protein	S	1
FT	#SUB	545	 567 	TYR	A	383	 405 	PHE	B	Protein	S	1
FT	#SUB	545	 567 	TYR	A	405	 427 	GLU	B	Protein	S	1
FT	#SUB	548	 570 	ILE	A	405	 427 	GLU	B	Protein	S	3
FT	#SUB	549	 571 	ALA	A	240	 262 	ASN	B	Protein	B	1
FT	#SUB	550	 572 	GLY	A	240	 262 	ASN	B	Protein	B	3
FT	#SUB	550	 572 	GLY	A	324	 346 	PHE	B	Protein	B	1
FT	#SUB	550	 572 	GLY	A	326	 348 	TYR	B	Protein	B	1
FT	#SUB	551	 573 	VAL	A	240	 262 	ASN	B	Protein	B	5
FT	#SUB	551	 573 	VAL	A	381	 403 	ILE	B	Protein	S	1
FT	#SUB	551	 573 	VAL	A	383	 405 	PHE	B	Protein	S	2
FT	#SUB	575	 597 	TYR	A	438	 460 	GLU	B	Protein	S	1
FT	#SUB	578	 600 	THR	A	239	 261 	PHE	B	Protein	S	2
FT	#SUB	578	 600 	THR	A	240	 262 	ASN	B	Protein	A	5
FT	#SUB	579	 601 	ASP	A	239	 261 	PHE	B	Protein	S	2
FT	#SUB	600	 622 	ILE	A	438	 460 	GLU	B	Protein	S	3
FT	#SUB	603	 625 	ASN	A	436	 458 	ASP	B	Protein	S	1
FT	#SUB	603	 625 	ASN	A	437	 459 	PHE	B	Protein	S	1
FT	#SUB	603	 625 	ASN	A	438	 460 	GLU	B	Protein	S	1
FT	#SUB	605	 627 	ASP	A	160	 182 	TYR	B	Protein	S	5
FT	#SUB	605	 627 	ASP	A	161	 183 	PHE	B	Protein	B	2
FT	#SUB	605	 627 	ASP	A	162	 184 	ASN	B	Protein	B	8
FT	#SUB	605	 627 	ASP	A	244	 266 	PRO	B	Protein	B	1
FT	#SUB	606	 628 	ASP	A	162	 184 	ASN	B	Protein	A	3
FT	#SUB	606	 628 	ASP	A	244	 266 	PRO	B	Protein	S	2
FT	#SUB	607	 629 	ASN	A	162	 184 	ASN	B	Protein	A	9
FT	#SUB	608	 630 	ARG	A	241	 263 	ALA	B	Protein	S	1
FT	#SUB	608	 630 	ARG	A	242	 264 	PRO	B	Protein	S	1
FT	#SUB	608	 630 	ARG	A	243	 265 	PHE	B	Protein	S	8
FT	#SUB	608	 630 	ARG	A	244	 266 	PRO	B	Protein	S	3
FT	#SUB	655	 677 	LYS	A	79	 101 	GLN	B	Protein	S	4
FT	#SUB	265	 287 	THR	A	345	 367 	LEU	C	Protein	S	2
FT	#SUB	266	 288 	GLN	A	372	 394 	PRO	C	Protein	S	1
FT	#SUB	266	 288 	GLN	A	373	 395 	ASN	C	Protein	S	1
FT	#SUB	287	 309 	ASN	A	345	 367 	LEU	C	Protein	B	1
FT	#SUB	289	 311 	PRO	A	315	 337 	PRO	C	Protein	S	2
FT	#SUB	289	 311 	PRO	A	316	 338 	ARG	C	Protein	A	6
FT	#SUB	289	 311 	PRO	A	345	 367 	LEU	C	Protein	S	1
FT	#SUB	290	 312 	HIS	A	346	 368 	SER	C	Protein	S	2
FT	#SUB	315	 337 	PRO	A	289	 311 	PRO	C	Protein	A	3
FT	#SUB	315	 337 	PRO	A	316	 338 	ARG	C	Protein	S	2
FT	#SUB	316	 338 	ARG	A	290	 312 	HIS	C	Protein	S	1
FT	#SUB	316	 338 	ARG	A	316	 338 	ARG	C	Protein	S	3
FT	#SUB	346	 368 	SER	A	290	 312 	HIS	C	Protein	S	2
FT	#SUB	372	 394 	PRO	A	265	 287 	THR	C	Protein	S	1
FT	#SUB	372	 394 	PRO	A	266	 288 	GLN	C	Protein	S	2
FT	#SUB	373	 395 	ASN	A	266	 288 	GLN	C	Protein	S	1
FT	#HET	204	 226 	LYS	A	2	2 	NAG	E	S	5
FT	#HET	206	 228 	PHE	A	1	1 	NAG	E	S	1
FT	#HET	208	 230 	SER	A	1	1 	NAG	E	S	2
FT	#HET	228	 250 	LEU	A	1	1 	NAG	E	S	1
FT	#HET	228	 250 	LEU	A	2	2 	NAG	E	S	4
FT	#HET	230	 252 	ASP	A	1	1 	NAG	E	S	9
FT	#HET	232	 254 	SER	A	1	1 	NAG	E	S	1
FT	#HET	242	 264 	PRO	A	34	903 	UPT	A	S	7
FT	#HET	243	 265 	PHE	A	34	903 	UPT	A	S	3
FT	#HET	269	 291 	TYR	A	2	2 	NAG	E	S	6
FT	#HET	269	 291 	TYR	A	33	902 	06S	A	S	5
FT	#HET	292	 314 	LYS	A	33	902 	06S	A	S	4
FT	#HET	293	 315 	VAL	A	33	902 	06S	A	S	1
FT	#HET	298	 320 	PHE	A	34	903 	UPT	A	S	16
FT	#HET	318	 340 	GLU	A	33	902 	06S	A	S	1
FT	#HET	319	 341 	ILE	A	33	902 	06S	A	S	3
FT	#HET	321	 343 	ASP	A	33	902 	06S	A	S	7
FT	#HET	324	 346 	PHE	A	34	903 	UPT	A	S	5
FT	#HET	326	 348 	TYR	A	32	901 	URI	A	S	7
FT	#HET	328	 350 	LYS	A	32	901 	URI	A	B	2
FT	#HET	329	 351 	GLY	A	32	901 	URI	A	B	1
FT	#HET	331	 353 	TYR	A	32	901 	URI	A	S	4
FT	#HET	351	 373 	HIS	A	33	902 	06S	A	S	22
FT	#HET	353	 375 	ARG	A	33	902 	06S	A	S	5
FT	#HET	353	 375 	ARG	A	34	903 	UPT	A	S	5
FT	#HET	356	 378 	VAL	A	32	901 	URI	A	S	4
FT	#HET	378	 400 	ASN	A	33	902 	06S	A	S	1
FT	#HET	381	 403 	ILE	A	34	903 	UPT	A	S	2
FT	#HET	383	 405 	PHE	A	32	901 	URI	A	S	28
FT	#HET	404	 426 	SER	A	6	1 	NAG	F	S	1
FT	#HET	407	 429 	ARG	A	32	901 	URI	A	S	5
FT	#HET	440	 462 	ASP	A	4	4 	MAN	E	S	2
FT	#HET	442	 464 	HIS	A	2	2 	NAG	E	B	4
FT	#HET	442	 464 	HIS	A	3	3 	BMA	E	B	2
FT	#HET	442	 464 	HIS	A	4	4 	MAN	E	S	2
FT	#HET	443	 465 	SER	A	2	2 	NAG	E	B	3
FT	#HET	444	 466 	ASN	A	1	1 	NAG	E	A	7
FT	#HET	444	 466 	ASN	A	2	2 	NAG	E	B	1
FT	#HET	444	 466 	ASN	A	33	902 	06S	A	S	1
FT	#HET	445	 467 	PHE	A	1	1 	NAG	E	A	5
FT	#HET	445	 467 	PHE	A	34	903 	UPT	A	B	4
FT	#HET	446	 468 	TYR	A	1	1 	NAG	E	S	1
FT	#HET	446	 468 	TYR	A	34	903 	UPT	A	A	9
FT	#HET	447	 469 	HIS	A	33	902 	06S	A	S	23
FT	#HET	447	 469 	HIS	A	34	903 	UPT	A	B	2
FT	#HET	448	 470 	PHE	A	33	902 	06S	A	B	6
FT	#HET	448	 470 	PHE	A	34	903 	UPT	A	S	4
FT	#HET	449	 471 	THR	A	33	902 	06S	A	A	11
FT	#HET	450	 472 	ARG	A	33	902 	06S	A	B	3
FT	#HET	452	 474 	LEU	A	33	902 	06S	A	S	2
FT	#HET	453	 475 	ILE	A	6	1 	NAG	F	A	3
FT	#HET	454	 476 	LYS	A	6	1 	NAG	F	A	6
FT	#HET	456	 478 	GLN	A	9	2 	NAG	G	S	12
FT	#HET	457	 479 	CYS	A	6	1 	NAG	F	S	1
FT	#HET	467	 489 	SER	A	6	1 	NAG	F	S	5
FT	#HET	468	 490 	LEU	A	6	1 	NAG	F	S	2
FT	#HET	491	 513 	SER	A	6	1 	NAG	F	S	2
FT	#HET	498	 520 	VAL	A	36	901 	URI	B	S	2
FT	#HET	512	 534 	TYR	A	6	1 	NAG	F	S	1
FT	#HET	512	 534 	TYR	A	9	2 	NAG	G	S	3
FT	#HET	514	 536 	ASP	A	6	1 	NAG	F	S	6
FT	#HET	521	 543 	ASP	A	36	901 	URI	B	S	6
FT	#HET	523	 545 	ASP	A	36	901 	URI	B	S	9
FT	#HET	536	 558 	VAL	A	9	2 	NAG	G	S	1
FT	#HET	538	 560 	ASP	A	8	1 	NAG	G	S	9
FT	#HET	540	 562 	SER	A	8	1 	NAG	G	S	2
FT	#HET	548	 570 	ILE	A	38	903 	UPT	B	S	1
FT	#HET	549	 571 	ALA	A	38	903 	UPT	B	A	3
FT	#HET	550	 572 	GLY	A	38	903 	UPT	B	B	3
FT	#HET	551	 573 	VAL	A	36	901 	URI	B	A	4
FT	#HET	552	 574 	THR	A	36	901 	URI	B	A	6
FT	#HET	566	 588 	VAL	A	8	1 	NAG	G	S	1
FT	#HET	586	 608 	LYS	A	35	913 	NAG	A	B	7
FT	#HET	587	 609 	SER	A	35	913 	NAG	A	A	5
FT	#HET	589	 611 	VAL	A	35	913 	NAG	A	S	2
FT	#HET	590	 612 	GLU	A	8	1 	NAG	G	S	4
FT	#HET	592	 614 	VAL	A	8	1 	NAG	G	S	3
FT	#MOD	271	 293 	ASN	A	1	1 	NAG	E	S
FT	#MOD	489	 511 	ASN	A	6	1 	NAG	F	S
FT	#MOD	568	 590 	ASN	A	8	1 	NAG	G	S
FT	#MOD	618	 640 	ASN	A	35	913 	NAG	A	S
FT	DISORDER	1	9
FT	DISORDER	20	22
FT	DISORDER	79	90
FT	DISORDER	412	435
FT	DISORDER	798	811
CC	SEQUENCE	749 AA (ATOM);
CC	RSYPCDEKKQ VIAECSNRRL QEVPQTVGKY VTELDLSDNF ITHITNESFQ GLQNLTKINL
CC	NHNPNVGLNI TDGAFLNLKN LRELLLEDNQ LPQIPSGLPE SLTELSLIQN NIYNITKEGI
CC	SRLINLKNLY LAWNCYFNKV CEKTNIEDGV FETLTNLELL SLSFNSLSHV PPKLPSSLRK
CC	LFLSNTQIKY ISEEDFKGLI NLTLLDLSGN CPRCFNAPFP CVPCDGGASI NIDRFAFQNL
CC	TQLRYLNLSS TSLRKINAAW FKNMPHLKVL DLEFNYLVGE IASGAFLTML PRLEILDLSF
CC	NYIKGSYPQH INISRNFSKL LSLRALHLRG YVFQELREDD FQPLMQLPNL STINLGINFI
CC	KQIDFKLFQN FSNLEIIYLS ENRISPLDFE FDPHSNFYHF TRPLIKPQCA AYGKALDLSL
CC	NSIFFIGPNQ FENLPDIACL NLSANSNAQV LSGTEFSAIP HVKYLDLTNN RLDFDNASAL
CC	TELSDLEVLD LSYNSHYFRI AGVTHHLEFI QNFTNLKVLN LSHNNIYTLT DKYNLESKSL
CC	VELVFSGNRL DILWNDDDNR YISIFKGLKN LTRLDLSLNR LKHIPNEAFL NLPASLTELH
CC	INDNMLKFFN WTLLQQFPRL ELLDLRGNKL LFLTDSLSDF TSSLRTLLLS HNRISHLPSG
CC	FLSEVSSLKH LDLSSNLLKT INKSALETKT TTKLSMLELH GNPFECTCDI GDFRRWMDEH
CC	LNVKIPRLVD VICASPGDQR GKSIVSLEL
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES RSPWEENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSD
CC	ATOM   ---------RSYPCDEKKQ---VIAECSNRRLQEVPQTVGKYVTELDLSD
CC	                **********   ****************************
CC	SEQRES NFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFL
CC	ATOM   NFITHITNESFQGLQNLTKINLNHNPNV------------GLNITDGAFL
CC	       ****************************            **********
CC	SEQRES NLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINL
CC	ATOM   NLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINL
CC	       **************************************************
CC	SEQRES KNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS
CC	ATOM   KNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS
CC	       **************************************************
CC	SEQRES SLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDG
CC	ATOM   SLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDG
CC	       **************************************************
CC	SEQRES GASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNY
CC	ATOM   GASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNY
CC	       **************************************************
CC	SEQRES LVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRAL
CC	ATOM   LVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRAL
CC	       **************************************************
CC	SEQRES HLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEI
CC	ATOM   HLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEI
CC	       **************************************************
CC	SEQRES IYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTR
CC	ATOM   IYLSENRISPL------------------------DFEFDPHSNFYHFTR
CC	       ***********                        ***************
CC	SEQRES PLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLS
CC	ATOM   PLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLS
CC	       **************************************************
CC	SEQRES GTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAG
CC	ATOM   GTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAG
CC	       **************************************************
CC	SEQRES VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI
CC	ATOM   VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI
CC	       **************************************************
CC	SEQRES LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHIN
CC	ATOM   LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHIN
CC	       **************************************************
CC	SEQRES DNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHN
CC	ATOM   DNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHN
CC	       **************************************************
CC	SEQRES RISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN
CC	ATOM   RISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN
CC	       **************************************************
CC	SEQRES PFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTC
CC	ATOM   PFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLEL---
CC	       ***********************************************   
CC	SEQRES VSDVTEFLVPR
CC	ATOM   -----------
CC	                  
SQ	SEQUENCE	811 AA;      MW;         CN;
	RSPWEENFSR SYPCDEKKQN DSVIAECSNR RLQEVPQTVG KYVTELDLSD NFITHITNES
	FQGLQNLTKI NLNHNPNVQH QNGNPGIQSN GLNITDGAFL NLKNLRELLL EDNQLPQIPS
	GLPESLTELS LIQNNIYNIT KEGISRLINL KNLYLAWNCY FNKVCEKTNI EDGVFETLTN
	LELLSLSFNS LSHVPPKLPS SLRKLFLSNT QIKYISEEDF KGLINLTLLD LSGNCPRCFN
	APFPCVPCDG GASINIDRFA FQNLTQLRYL NLSSTSLRKI NAAWFKNMPH LKVLDLEFNY
	LVGEIASGAF LTMLPRLEIL DLSFNYIKGS YPQHINISRN FSKLLSLRAL HLRGYVFQEL
	REDDFQPLMQ LPNLSTINLG INFIKQIDFK LFQNFSNLEI IYLSENRISP LVKDTRQSYA
	NSSSFQRHIR KRRSTDFEFD PHSNFYHFTR PLIKPQCAAY GKALDLSLNS IFFIGPNQFE
	NLPDIACLNL SANSNAQVLS GTEFSAIPHV KYLDLTNNRL DFDNASALTE LSDLEVLDLS
	YNSHYFRIAG VTHHLEFIQN FTNLKVLNLS HNNIYTLTDK YNLESKSLVE LVFSGNRLDI
	LWNDDDNRYI SIFKGLKNLT RLDLSLNRLK HIPNEAFLNL PASLTELHIN DNMLKFFNWT
	LLQQFPRLEL LDLRGNKLLF LTDSLSDFTS SLRTLLLSHN RISHLPSGFL SEVSSLKHLD
	LSSNLLKTIN KSALETKTTT KLSMLELHGN PFECTCDIGD FRRWMDEHLN VKIPRLVDVI
	CASPGDQRGK SIVSLELTTC VSDVTEFLVP R
//
ID	4R09B	STANDARD;	PRT;	811	AA.
DT	CONVERTED FROM PDB (SEQRES) 4R09
DE	Toll-like receptor 8
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.620
CC	R-Factor	0.220
FT	#SUB	79	 101 	GLN	B	655	 677 	LYS	A	Protein	S	4
FT	#SUB	160	 182 	TYR	B	605	 627 	ASP	A	Protein	S	5
FT	#SUB	161	 183 	PHE	B	605	 627 	ASP	A	Protein	A	2
FT	#SUB	162	 184 	ASN	B	605	 627 	ASP	A	Protein	A	8
FT	#SUB	162	 184 	ASN	B	606	 628 	ASP	A	Protein	S	3
FT	#SUB	162	 184 	ASN	B	607	 629 	ASN	A	Protein	S	9
FT	#SUB	239	 261 	PHE	B	578	 600 	THR	A	Protein	S	2
FT	#SUB	239	 261 	PHE	B	579	 601 	ASP	A	Protein	S	2
FT	#SUB	240	 262 	ASN	B	549	 571 	ALA	A	Protein	S	1
FT	#SUB	240	 262 	ASN	B	550	 572 	GLY	A	Protein	S	3
FT	#SUB	240	 262 	ASN	B	551	 573 	VAL	A	Protein	S	5
FT	#SUB	240	 262 	ASN	B	578	 600 	THR	A	Protein	S	5
FT	#SUB	241	 263 	ALA	B	608	 630 	ARG	A	Protein	B	1
FT	#SUB	242	 264 	PRO	B	608	 630 	ARG	A	Protein	B	1
FT	#SUB	243	 265 	PHE	B	608	 630 	ARG	A	Protein	B	8
FT	#SUB	244	 266 	PRO	B	605	 627 	ASP	A	Protein	S	1
FT	#SUB	244	 266 	PRO	B	606	 628 	ASP	A	Protein	S	2
FT	#SUB	244	 266 	PRO	B	608	 630 	ARG	A	Protein	B	3
FT	#SUB	324	 346 	PHE	B	550	 572 	GLY	A	Protein	S	1
FT	#SUB	326	 348 	TYR	B	550	 572 	GLY	A	Protein	S	1
FT	#SUB	381	 403 	ILE	B	551	 573 	VAL	A	Protein	S	1
FT	#SUB	383	 405 	PHE	B	521	 543 	ASP	A	Protein	S	3
FT	#SUB	383	 405 	PHE	B	545	 567 	TYR	A	Protein	S	1
FT	#SUB	383	 405 	PHE	B	551	 573 	VAL	A	Protein	S	2
FT	#SUB	405	 427 	GLU	B	544	 566 	HIS	A	Protein	S	5
FT	#SUB	405	 427 	GLU	B	545	 567 	TYR	A	Protein	S	1
FT	#SUB	405	 427 	GLU	B	548	 570 	ILE	A	Protein	S	3
FT	#SUB	407	 429 	ARG	B	496	 518 	ALA	A	Protein	S	5
FT	#SUB	407	 429 	ARG	B	498	 520 	VAL	A	Protein	S	1
FT	#SUB	407	 429 	ARG	B	521	 543 	ASP	A	Protein	S	3
FT	#SUB	409	 431 	SER	B	472	 494 	PHE	A	Protein	S	3
FT	#SUB	436	 458 	ASP	B	603	 625 	ASN	A	Protein	B	1
FT	#SUB	437	 459 	PHE	B	603	 625 	ASN	A	Protein	B	1
FT	#SUB	438	 460 	GLU	B	575	 597 	TYR	A	Protein	S	1
FT	#SUB	438	 460 	GLU	B	600	 622 	ILE	A	Protein	S	3
FT	#SUB	438	 460 	GLU	B	603	 625 	ASN	A	Protein	B	1
FT	#SUB	468	 490 	LEU	B	544	 566 	HIS	A	Protein	S	1
FT	#SUB	469	 491 	ASN	B	519	 541 	ARG	A	Protein	B	2
FT	#SUB	470	 492 	SER	B	472	 494 	PHE	A	Protein	S	3
FT	#SUB	472	 494 	PHE	B	409	 431 	SER	A	Protein	S	3
FT	#SUB	472	 494 	PHE	B	470	 492 	SER	A	Protein	S	3
FT	#SUB	472	 494 	PHE	B	472	 494 	PHE	A	Protein	S	4
FT	#SUB	492	 514 	ALA	B	519	 541 	ARG	A	Protein	A	5
FT	#SUB	494	 516 	SER	B	494	 516 	SER	A	Protein	S	4
FT	#SUB	496	 518 	ALA	B	407	 429 	ARG	A	Protein	A	6
FT	#SUB	498	 520 	VAL	B	407	 429 	ARG	A	Protein	S	1
FT	#SUB	519	 541 	ARG	B	468	 490 	LEU	A	Protein	S	1
FT	#SUB	519	 541 	ARG	B	469	 491 	ASN	A	Protein	S	3
FT	#SUB	519	 541 	ARG	B	492	 514 	ALA	A	Protein	S	4
FT	#SUB	521	 543 	ASP	B	383	 405 	PHE	A	Protein	S	2
FT	#SUB	521	 543 	ASP	B	407	 429 	ARG	A	Protein	S	3
FT	#SUB	544	 566 	HIS	B	405	 427 	GLU	A	Protein	S	6
FT	#SUB	544	 566 	HIS	B	468	 490 	LEU	A	Protein	S	1
FT	#SUB	545	 567 	TYR	B	383	 405 	PHE	A	Protein	S	1
FT	#SUB	545	 567 	TYR	B	405	 427 	GLU	A	Protein	S	1
FT	#SUB	548	 570 	ILE	B	405	 427 	GLU	A	Protein	S	4
FT	#SUB	549	 571 	ALA	B	240	 262 	ASN	A	Protein	B	1
FT	#SUB	550	 572 	GLY	B	240	 262 	ASN	A	Protein	B	2
FT	#SUB	550	 572 	GLY	B	324	 346 	PHE	A	Protein	B	4
FT	#SUB	550	 572 	GLY	B	326	 348 	TYR	A	Protein	B	2
FT	#SUB	551	 573 	VAL	B	240	 262 	ASN	A	Protein	B	4
FT	#SUB	551	 573 	VAL	B	381	 403 	ILE	A	Protein	S	1
FT	#SUB	551	 573 	VAL	B	383	 405 	PHE	A	Protein	S	2
FT	#SUB	552	 574 	THR	B	239	 261 	PHE	A	Protein	S	2
FT	#SUB	552	 574 	THR	B	240	 262 	ASN	A	Protein	B	2
FT	#SUB	576	 598 	THR	B	242	 264 	PRO	A	Protein	S	1
FT	#SUB	578	 600 	THR	B	239	 261 	PHE	A	Protein	S	2
FT	#SUB	578	 600 	THR	B	240	 262 	ASN	A	Protein	A	5
FT	#SUB	579	 601 	ASP	B	239	 261 	PHE	A	Protein	S	2
FT	#SUB	600	 622 	ILE	B	438	 460 	GLU	A	Protein	S	3
FT	#SUB	603	 625 	ASN	B	436	 458 	ASP	A	Protein	S	1
FT	#SUB	603	 625 	ASN	B	438	 460 	GLU	A	Protein	S	1
FT	#SUB	605	 627 	ASP	B	160	 182 	TYR	A	Protein	S	8
FT	#SUB	605	 627 	ASP	B	161	 183 	PHE	A	Protein	B	1
FT	#SUB	605	 627 	ASP	B	162	 184 	ASN	A	Protein	B	3
FT	#SUB	605	 627 	ASP	B	163	 185 	LYS	A	Protein	S	3
FT	#SUB	605	 627 	ASP	B	244	 266 	PRO	A	Protein	B	1
FT	#SUB	606	 628 	ASP	B	162	 184 	ASN	A	Protein	A	3
FT	#SUB	606	 628 	ASP	B	244	 266 	PRO	A	Protein	A	6
FT	#SUB	607	 629 	ASN	B	162	 184 	ASN	A	Protein	A	9
FT	#SUB	608	 630 	ARG	B	241	 263 	ALA	A	Protein	S	1
FT	#SUB	608	 630 	ARG	B	242	 264 	PRO	A	Protein	S	1
FT	#SUB	608	 630 	ARG	B	243	 265 	PHE	A	Protein	S	9
FT	#SUB	608	 630 	ARG	B	244	 266 	PRO	A	Protein	S	5
FT	#SUB	631	 653 	HIS	B	436	 458 	ASP	A	Protein	S	1
FT	#HET	204	 226 	LYS	B	11	2 	NAG	H	S	3
FT	#HET	206	 228 	PHE	B	10	1 	NAG	H	S	1
FT	#HET	208	 230 	SER	B	10	1 	NAG	H	S	2
FT	#HET	228	 250 	LEU	B	11	2 	NAG	H	S	4
FT	#HET	230	 252 	ASP	B	10	1 	NAG	H	S	10
FT	#HET	232	 254 	SER	B	10	1 	NAG	H	S	2
FT	#HET	242	 264 	PRO	B	38	903 	UPT	B	S	3
FT	#HET	243	 265 	PHE	B	38	903 	UPT	B	S	4
FT	#HET	269	 291 	TYR	B	11	2 	NAG	H	S	7
FT	#HET	269	 291 	TYR	B	37	902 	06S	B	S	7
FT	#HET	292	 314 	LYS	B	37	902 	06S	B	S	4
FT	#HET	293	 315 	VAL	B	37	902 	06S	B	S	1
FT	#HET	298	 320 	PHE	B	38	903 	UPT	B	S	10
FT	#HET	319	 341 	ILE	B	37	902 	06S	B	S	3
FT	#HET	321	 343 	ASP	B	37	902 	06S	B	S	6
FT	#HET	324	 346 	PHE	B	38	903 	UPT	B	S	5
FT	#HET	326	 348 	TYR	B	36	901 	URI	B	S	5
FT	#HET	328	 350 	LYS	B	36	901 	URI	B	A	2
FT	#HET	329	 351 	GLY	B	36	901 	URI	B	B	4
FT	#HET	331	 353 	TYR	B	36	901 	URI	B	S	9
FT	#HET	351	 373 	HIS	B	37	902 	06S	B	S	25
FT	#HET	353	 375 	ARG	B	37	902 	06S	B	S	6
FT	#HET	353	 375 	ARG	B	38	903 	UPT	B	S	6
FT	#HET	356	 378 	VAL	B	36	901 	URI	B	S	2
FT	#HET	378	 400 	ASN	B	37	902 	06S	B	S	2
FT	#HET	381	 403 	ILE	B	38	903 	UPT	B	S	2
FT	#HET	383	 405 	PHE	B	36	901 	URI	B	S	25
FT	#HET	404	 426 	SER	B	13	1 	NAG	I	S	1
FT	#HET	407	 429 	ARG	B	36	901 	URI	B	S	5
FT	#HET	442	 464 	HIS	B	11	2 	NAG	H	B	3
FT	#HET	442	 464 	HIS	B	12	3 	BMA	H	B	1
FT	#HET	443	 465 	SER	B	11	2 	NAG	H	B	1
FT	#HET	444	 466 	ASN	B	10	1 	NAG	H	A	7
FT	#HET	444	 466 	ASN	B	11	2 	NAG	H	B	1
FT	#HET	444	 466 	ASN	B	37	902 	06S	B	S	1
FT	#HET	445	 467 	PHE	B	10	1 	NAG	H	A	5
FT	#HET	445	 467 	PHE	B	38	903 	UPT	B	B	4
FT	#HET	446	 468 	TYR	B	38	903 	UPT	B	A	7
FT	#HET	447	 469 	HIS	B	37	902 	06S	B	S	17
FT	#HET	447	 469 	HIS	B	38	903 	UPT	B	B	3
FT	#HET	448	 470 	PHE	B	37	902 	06S	B	B	6
FT	#HET	448	 470 	PHE	B	38	903 	UPT	B	S	7
FT	#HET	449	 471 	THR	B	37	902 	06S	B	A	12
FT	#HET	450	 472 	ARG	B	37	902 	06S	B	B	3
FT	#HET	452	 474 	LEU	B	37	902 	06S	B	S	2
FT	#HET	453	 475 	ILE	B	13	1 	NAG	I	A	3
FT	#HET	454	 476 	LYS	B	13	1 	NAG	I	A	4
FT	#HET	456	 478 	GLN	B	16	2 	NAG	J	S	10
FT	#HET	457	 479 	CYS	B	13	1 	NAG	I	S	2
FT	#HET	465	 487 	ASP	B	13	1 	NAG	I	S	2
FT	#HET	467	 489 	SER	B	13	1 	NAG	I	S	4
FT	#HET	468	 490 	LEU	B	13	1 	NAG	I	S	2
FT	#HET	498	 520 	VAL	B	32	901 	URI	A	S	1
FT	#HET	512	 534 	TYR	B	13	1 	NAG	I	S	1
FT	#HET	512	 534 	TYR	B	16	2 	NAG	J	S	3
FT	#HET	514	 536 	ASP	B	13	1 	NAG	I	S	7
FT	#HET	516	 538 	THR	B	15	1 	NAG	J	S	1
FT	#HET	521	 543 	ASP	B	32	901 	URI	A	S	6
FT	#HET	523	 545 	ASP	B	32	901 	URI	A	S	13
FT	#HET	538	 560 	ASP	B	15	1 	NAG	J	S	8
FT	#HET	540	 562 	SER	B	15	1 	NAG	J	S	3
FT	#HET	548	 570 	ILE	B	34	903 	UPT	A	S	1
FT	#HET	549	 571 	ALA	B	34	903 	UPT	A	A	4
FT	#HET	550	 572 	GLY	B	34	903 	UPT	A	B	4
FT	#HET	551	 573 	VAL	B	32	901 	URI	A	A	4
FT	#HET	552	 574 	THR	B	32	901 	URI	A	A	4
FT	#HET	562	 584 	THR	B	39	911 	NAG	B	B	1
FT	#HET	566	 588 	VAL	B	15	1 	NAG	J	S	1
FT	#HET	586	 608 	LYS	B	39	911 	NAG	B	B	5
FT	#HET	587	 609 	SER	B	39	911 	NAG	B	A	4
FT	#HET	589	 611 	VAL	B	39	911 	NAG	B	S	3
FT	#HET	590	 612 	GLU	B	15	1 	NAG	J	S	5
FT	#HET	592	 614 	VAL	B	15	1 	NAG	J	S	2
FT	#MOD	271	 293 	ASN	B	10	1 	NAG	H	S
FT	#MOD	489	 511 	ASN	B	13	1 	NAG	I	S
FT	#MOD	568	 590 	ASN	B	15	1 	NAG	J	S
FT	#MOD	618	 640 	ASN	B	39	911 	NAG	B	S
FT	DISORDER	1	9
FT	DISORDER	20	20
FT	DISORDER	80	89
FT	DISORDER	411	435
FT	DISORDER	798	811
CC	SEQUENCE	752 AA (ATOM);
CC	RSYPCDEKKQ DSVIAECSNR RLQEVPQTVG KYVTELDLSD NFITHITNES FQGLQNLTKI
CC	NLNHNPNVQN GLNITDGAFL NLKNLRELLL EDNQLPQIPS GLPESLTELS LIQNNIYNIT
CC	KEGISRLINL KNLYLAWNCY FNKVCEKTNI EDGVFETLTN LELLSLSFNS LSHVPPKLPS
CC	SLRKLFLSNT QIKYISEEDF KGLINLTLLD LSGNCPRCFN APFPCVPCDG GASINIDRFA
CC	FQNLTQLRYL NLSSTSLRKI NAAWFKNMPH LKVLDLEFNY LVGEIASGAF LTMLPRLEIL
CC	DLSFNYIKGS YPQHINISRN FSKLLSLRAL HLRGYVFQEL REDDFQPLMQ LPNLSTINLG
CC	INFIKQIDFK LFQNFSNLEI IYLSENRISP DFEFDPHSNF YHFTRPLIKP QCAAYGKALD
CC	LSLNSIFFIG PNQFENLPDI ACLNLSANSN AQVLSGTEFS AIPHVKYLDL TNNRLDFDNA
CC	SALTELSDLE VLDLSYNSHY FRIAGVTHHL EFIQNFTNLK VLNLSHNNIY TLTDKYNLES
CC	KSLVELVFSG NRLDILWNDD DNRYISIFKG LKNLTRLDLS LNRLKHIPNE AFLNLPASLT
CC	ELHINDNMLK FFNWTLLQQF PRLELLDLRG NKLLFLTDSL SDFTSSLRTL LLSHNRISHL
CC	PSGFLSEVSS LKHLDLSSNL LKTINKSALE TKTTTKLSML ELHGNPFECT CDIGDFRRWM
CC	DEHLNVKIPR LVDVICASPG DQRGKSIVSL EL
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES RSPWEENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSD
CC	ATOM   ---------RSYPCDEKKQ-DSVIAECSNRRLQEVPQTVGKYVTELDLSD
CC	                ********** ******************************
CC	SEQRES NFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFL
CC	ATOM   NFITHITNESFQGLQNLTKINLNHNPNVQ----------NGLNITDGAFL
CC	       *****************************          ***********
CC	SEQRES NLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINL
CC	ATOM   NLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINL
CC	       **************************************************
CC	SEQRES KNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS
CC	ATOM   KNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS
CC	       **************************************************
CC	SEQRES SLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDG
CC	ATOM   SLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDG
CC	       **************************************************
CC	SEQRES GASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNY
CC	ATOM   GASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNY
CC	       **************************************************
CC	SEQRES LVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRAL
CC	ATOM   LVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRAL
CC	       **************************************************
CC	SEQRES HLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEI
CC	ATOM   HLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEI
CC	       **************************************************
CC	SEQRES IYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTR
CC	ATOM   IYLSENRISP-------------------------DFEFDPHSNFYHFTR
CC	       **********                         ***************
CC	SEQRES PLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLS
CC	ATOM   PLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLS
CC	       **************************************************
CC	SEQRES GTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAG
CC	ATOM   GTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAG
CC	       **************************************************
CC	SEQRES VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI
CC	ATOM   VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI
CC	       **************************************************
CC	SEQRES LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHIN
CC	ATOM   LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHIN
CC	       **************************************************
CC	SEQRES DNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHN
CC	ATOM   DNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHN
CC	       **************************************************
CC	SEQRES RISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN
CC	ATOM   RISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN
CC	       **************************************************
CC	SEQRES PFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTC
CC	ATOM   PFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLEL---
CC	       ***********************************************   
CC	SEQRES VSDVTEFLVPR
CC	ATOM   -----------
CC	                  
SQ	SEQUENCE	811 AA;      MW;         CN;
	RSPWEENFSR SYPCDEKKQN DSVIAECSNR RLQEVPQTVG KYVTELDLSD NFITHITNES
	FQGLQNLTKI NLNHNPNVQH QNGNPGIQSN GLNITDGAFL NLKNLRELLL EDNQLPQIPS
	GLPESLTELS LIQNNIYNIT KEGISRLINL KNLYLAWNCY FNKVCEKTNI EDGVFETLTN
	LELLSLSFNS LSHVPPKLPS SLRKLFLSNT QIKYISEEDF KGLINLTLLD LSGNCPRCFN
	APFPCVPCDG GASINIDRFA FQNLTQLRYL NLSSTSLRKI NAAWFKNMPH LKVLDLEFNY
	LVGEIASGAF LTMLPRLEIL DLSFNYIKGS YPQHINISRN FSKLLSLRAL HLRGYVFQEL
	REDDFQPLMQ LPNLSTINLG INFIKQIDFK LFQNFSNLEI IYLSENRISP LVKDTRQSYA
	NSSSFQRHIR KRRSTDFEFD PHSNFYHFTR PLIKPQCAAY GKALDLSLNS IFFIGPNQFE
	NLPDIACLNL SANSNAQVLS GTEFSAIPHV KYLDLTNNRL DFDNASALTE LSDLEVLDLS
	YNSHYFRIAG VTHHLEFIQN FTNLKVLNLS HNNIYTLTDK YNLESKSLVE LVFSGNRLDI
	LWNDDDNRYI SIFKGLKNLT RLDLSLNRLK HIPNEAFLNL PASLTELHIN DNMLKFFNWT
	LLQQFPRLEL LDLRGNKLLF LTDSLSDFTS SLRTLLLSHN RISHLPSGFL SEVSSLKHLD
	LSSNLLKTIN KSALETKTTT KLSMLELHGN PFECTCDIGD FRRWMDEHLN VKIPRLVDVI
	CASPGDQRGK SIVSLELTTC VSDVTEFLVP R
//
ID	4R09C	STANDARD;	PRT;	811	AA.
DT	CONVERTED FROM PDB (SEQRES) 4R09
DE	Toll-like receptor 8
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.620
CC	R-Factor	0.220
FT	#SUB	265	 287 	THR	C	372	 394 	PRO	A	Protein	S	1
FT	#SUB	266	 288 	GLN	C	372	 394 	PRO	A	Protein	S	2
FT	#SUB	266	 288 	GLN	C	373	 395 	ASN	A	Protein	S	1
FT	#SUB	289	 311 	PRO	C	315	 337 	PRO	A	Protein	S	3
FT	#SUB	290	 312 	HIS	C	316	 338 	ARG	A	Protein	S	1
FT	#SUB	290	 312 	HIS	C	346	 368 	SER	A	Protein	S	2
FT	#SUB	315	 337 	PRO	C	289	 311 	PRO	A	Protein	A	2
FT	#SUB	316	 338 	ARG	C	289	 311 	PRO	A	Protein	S	6
FT	#SUB	316	 338 	ARG	C	315	 337 	PRO	A	Protein	S	2
FT	#SUB	316	 338 	ARG	C	316	 338 	ARG	A	Protein	S	3
FT	#SUB	345	 367 	LEU	C	265	 287 	THR	A	Protein	S	2
FT	#SUB	345	 367 	LEU	C	287	 309 	ASN	A	Protein	S	1
FT	#SUB	345	 367 	LEU	C	289	 311 	PRO	A	Protein	S	1
FT	#SUB	346	 368 	SER	C	290	 312 	HIS	A	Protein	S	2
FT	#SUB	372	 394 	PRO	C	266	 288 	GLN	A	Protein	S	1
FT	#SUB	373	 395 	ASN	C	266	 288 	GLN	A	Protein	S	1
FT	#SUB	160	 182 	TYR	C	605	 627 	ASP	D	Protein	S	5
FT	#SUB	161	 183 	PHE	C	605	 627 	ASP	D	Protein	A	2
FT	#SUB	162	 184 	ASN	C	605	 627 	ASP	D	Protein	A	7
FT	#SUB	162	 184 	ASN	C	606	 628 	ASP	D	Protein	S	2
FT	#SUB	162	 184 	ASN	C	607	 629 	ASN	D	Protein	S	8
FT	#SUB	239	 261 	PHE	C	552	 574 	THR	D	Protein	S	1
FT	#SUB	239	 261 	PHE	C	578	 600 	THR	D	Protein	S	2
FT	#SUB	239	 261 	PHE	C	579	 601 	ASP	D	Protein	S	2
FT	#SUB	240	 262 	ASN	C	549	 571 	ALA	D	Protein	S	1
FT	#SUB	240	 262 	ASN	C	550	 572 	GLY	D	Protein	S	2
FT	#SUB	240	 262 	ASN	C	551	 573 	VAL	D	Protein	S	5
FT	#SUB	240	 262 	ASN	C	552	 574 	THR	D	Protein	S	2
FT	#SUB	240	 262 	ASN	C	578	 600 	THR	D	Protein	S	5
FT	#SUB	241	 263 	ALA	C	608	 630 	ARG	D	Protein	B	3
FT	#SUB	242	 264 	PRO	C	608	 630 	ARG	D	Protein	B	2
FT	#SUB	243	 265 	PHE	C	608	 630 	ARG	D	Protein	B	8
FT	#SUB	244	 266 	PRO	C	605	 627 	ASP	D	Protein	S	1
FT	#SUB	244	 266 	PRO	C	606	 628 	ASP	D	Protein	S	3
FT	#SUB	244	 266 	PRO	C	608	 630 	ARG	D	Protein	B	4
FT	#SUB	324	 346 	PHE	C	550	 572 	GLY	D	Protein	S	4
FT	#SUB	326	 348 	TYR	C	550	 572 	GLY	D	Protein	S	1
FT	#SUB	381	 403 	ILE	C	551	 573 	VAL	D	Protein	S	1
FT	#SUB	383	 405 	PHE	C	521	 543 	ASP	D	Protein	S	2
FT	#SUB	383	 405 	PHE	C	545	 567 	TYR	D	Protein	S	1
FT	#SUB	383	 405 	PHE	C	551	 573 	VAL	D	Protein	S	2
FT	#SUB	405	 427 	GLU	C	544	 566 	HIS	D	Protein	S	6
FT	#SUB	405	 427 	GLU	C	545	 567 	TYR	D	Protein	S	1
FT	#SUB	405	 427 	GLU	C	548	 570 	ILE	D	Protein	S	3
FT	#SUB	407	 429 	ARG	C	496	 518 	ALA	D	Protein	S	3
FT	#SUB	407	 429 	ARG	C	497	 519 	GLN	D	Protein	S	3
FT	#SUB	407	 429 	ARG	C	521	 543 	ASP	D	Protein	S	2
FT	#SUB	407	 429 	ARG	C	545	 567 	TYR	D	Protein	S	1
FT	#SUB	409	 431 	SER	C	472	 494 	PHE	D	Protein	S	2
FT	#SUB	436	 458 	ASP	C	603	 625 	ASN	D	Protein	B	1
FT	#SUB	436	 458 	ASP	C	631	 653 	HIS	D	Protein	S	1
FT	#SUB	438	 460 	GLU	C	600	 622 	ILE	D	Protein	S	4
FT	#SUB	468	 490 	LEU	C	519	 541 	ARG	D	Protein	B	1
FT	#SUB	468	 490 	LEU	C	544	 566 	HIS	D	Protein	S	2
FT	#SUB	469	 491 	ASN	C	519	 541 	ARG	D	Protein	B	4
FT	#SUB	470	 492 	SER	C	472	 494 	PHE	D	Protein	S	3
FT	#SUB	472	 494 	PHE	C	409	 431 	SER	D	Protein	S	2
FT	#SUB	472	 494 	PHE	C	470	 492 	SER	D	Protein	S	3
FT	#SUB	472	 494 	PHE	C	472	 494 	PHE	D	Protein	S	4
FT	#SUB	492	 514 	ALA	C	519	 541 	ARG	D	Protein	B	4
FT	#SUB	494	 516 	SER	C	494	 516 	SER	D	Protein	S	4
FT	#SUB	496	 518 	ALA	C	407	 429 	ARG	D	Protein	A	5
FT	#SUB	498	 520 	VAL	C	407	 429 	ARG	D	Protein	S	1
FT	#SUB	519	 541 	ARG	C	469	 491 	ASN	D	Protein	S	5
FT	#SUB	519	 541 	ARG	C	492	 514 	ALA	D	Protein	S	4
FT	#SUB	521	 543 	ASP	C	383	 405 	PHE	D	Protein	S	2
FT	#SUB	521	 543 	ASP	C	407	 429 	ARG	D	Protein	S	3
FT	#SUB	544	 566 	HIS	C	405	 427 	GLU	D	Protein	S	6
FT	#SUB	544	 566 	HIS	C	468	 490 	LEU	D	Protein	S	2
FT	#SUB	545	 567 	TYR	C	383	 405 	PHE	D	Protein	S	1
FT	#SUB	545	 567 	TYR	C	405	 427 	GLU	D	Protein	S	2
FT	#SUB	548	 570 	ILE	C	405	 427 	GLU	D	Protein	S	3
FT	#SUB	549	 571 	ALA	C	240	 262 	ASN	D	Protein	B	1
FT	#SUB	550	 572 	GLY	C	240	 262 	ASN	D	Protein	B	2
FT	#SUB	550	 572 	GLY	C	324	 346 	PHE	D	Protein	B	4
FT	#SUB	550	 572 	GLY	C	326	 348 	TYR	D	Protein	B	1
FT	#SUB	551	 573 	VAL	C	240	 262 	ASN	D	Protein	B	6
FT	#SUB	551	 573 	VAL	C	381	 403 	ILE	D	Protein	S	1
FT	#SUB	551	 573 	VAL	C	383	 405 	PHE	D	Protein	S	1
FT	#SUB	552	 574 	THR	C	240	 262 	ASN	D	Protein	B	1
FT	#SUB	576	 598 	THR	C	242	 264 	PRO	D	Protein	S	1
FT	#SUB	578	 600 	THR	C	239	 261 	PHE	D	Protein	S	2
FT	#SUB	578	 600 	THR	C	240	 262 	ASN	D	Protein	S	4
FT	#SUB	600	 622 	ILE	C	438	 460 	GLU	D	Protein	S	2
FT	#SUB	603	 625 	ASN	C	438	 460 	GLU	D	Protein	S	2
FT	#SUB	605	 627 	ASP	C	160	 182 	TYR	D	Protein	S	5
FT	#SUB	605	 627 	ASP	C	161	 183 	PHE	D	Protein	B	1
FT	#SUB	605	 627 	ASP	C	162	 184 	ASN	D	Protein	B	4
FT	#SUB	605	 627 	ASP	C	163	 185 	LYS	D	Protein	S	2
FT	#SUB	605	 627 	ASP	C	244	 266 	PRO	D	Protein	B	1
FT	#SUB	606	 628 	ASP	C	162	 184 	ASN	D	Protein	A	3
FT	#SUB	606	 628 	ASP	C	244	 266 	PRO	D	Protein	S	5
FT	#SUB	607	 629 	ASN	C	162	 184 	ASN	D	Protein	A	8
FT	#SUB	608	 630 	ARG	C	241	 263 	ALA	D	Protein	S	1
FT	#SUB	608	 630 	ARG	C	242	 264 	PRO	D	Protein	S	2
FT	#SUB	608	 630 	ARG	C	243	 265 	PHE	D	Protein	S	11
FT	#SUB	608	 630 	ARG	C	244	 266 	PRO	D	Protein	S	6
FT	#HET	204	 226 	LYS	C	18	2 	NAG	K	S	3
FT	#HET	206	 228 	PHE	C	17	1 	NAG	K	S	1
FT	#HET	208	 230 	SER	C	17	1 	NAG	K	S	2
FT	#HET	228	 250 	LEU	C	18	2 	NAG	K	S	3
FT	#HET	230	 252 	ASP	C	17	1 	NAG	K	S	10
FT	#HET	232	 254 	SER	C	17	1 	NAG	K	S	3
FT	#HET	242	 264 	PRO	C	41	902 	UPT	C	S	5
FT	#HET	243	 265 	PHE	C	41	902 	UPT	C	S	3
FT	#HET	269	 291 	TYR	C	18	2 	NAG	K	S	4
FT	#HET	269	 291 	TYR	C	40	901 	06S	C	S	5
FT	#HET	292	 314 	LYS	C	40	901 	06S	C	S	3
FT	#HET	293	 315 	VAL	C	17	1 	NAG	K	S	1
FT	#HET	293	 315 	VAL	C	40	901 	06S	C	S	2
FT	#HET	298	 320 	PHE	C	41	902 	UPT	C	S	11
FT	#HET	319	 341 	ILE	C	40	901 	06S	C	S	2
FT	#HET	321	 343 	ASP	C	40	901 	06S	C	S	6
FT	#HET	324	 346 	PHE	C	41	902 	UPT	C	S	4
FT	#HET	326	 348 	TYR	C	42	901 	URI	D	S	8
FT	#HET	328	 350 	LYS	C	42	901 	URI	D	B	1
FT	#HET	329	 351 	GLY	C	42	901 	URI	D	B	2
FT	#HET	331	 353 	TYR	C	42	901 	URI	D	S	3
FT	#HET	348	 370 	ARG	C	40	901 	06S	C	S	1
FT	#HET	351	 373 	HIS	C	40	901 	06S	C	S	15
FT	#HET	353	 375 	ARG	C	40	901 	06S	C	S	4
FT	#HET	353	 375 	ARG	C	41	902 	UPT	C	S	6
FT	#HET	356	 378 	VAL	C	42	901 	URI	D	S	2
FT	#HET	378	 400 	ASN	C	40	901 	06S	C	S	1
FT	#HET	381	 403 	ILE	C	41	902 	UPT	C	S	2
FT	#HET	383	 405 	PHE	C	42	901 	URI	D	S	26
FT	#HET	407	 429 	ARG	C	42	901 	URI	D	S	5
FT	#HET	440	 462 	ASP	C	20	4 	MAN	K	S	3
FT	#HET	442	 464 	HIS	C	18	2 	NAG	K	B	4
FT	#HET	442	 464 	HIS	C	19	3 	BMA	K	B	2
FT	#HET	442	 464 	HIS	C	20	4 	MAN	K	A	4
FT	#HET	443	 465 	SER	C	18	2 	NAG	K	B	3
FT	#HET	444	 466 	ASN	C	17	1 	NAG	K	A	7
FT	#HET	444	 466 	ASN	C	40	901 	06S	C	S	1
FT	#HET	445	 467 	PHE	C	17	1 	NAG	K	A	5
FT	#HET	445	 467 	PHE	C	41	902 	UPT	C	B	4
FT	#HET	446	 468 	TYR	C	17	1 	NAG	K	S	1
FT	#HET	446	 468 	TYR	C	41	902 	UPT	C	A	6
FT	#HET	447	 469 	HIS	C	40	901 	06S	C	S	26
FT	#HET	447	 469 	HIS	C	41	902 	UPT	C	B	3
FT	#HET	448	 470 	PHE	C	40	901 	06S	C	B	5
FT	#HET	448	 470 	PHE	C	41	902 	UPT	C	S	6
FT	#HET	449	 471 	THR	C	40	901 	06S	C	A	8
FT	#HET	450	 472 	ARG	C	40	901 	06S	C	B	2
FT	#HET	452	 474 	LEU	C	40	901 	06S	C	S	1
FT	#HET	453	 475 	ILE	C	22	1 	NAG	L	A	3
FT	#HET	454	 476 	LYS	C	22	1 	NAG	L	A	4
FT	#HET	456	 478 	GLN	C	26	2 	NAG	M	S	11
FT	#HET	457	 479 	CYS	C	22	1 	NAG	L	S	2
FT	#HET	467	 489 	SER	C	22	1 	NAG	L	S	5
FT	#HET	468	 490 	LEU	C	22	1 	NAG	L	S	2
FT	#HET	498	 520 	VAL	C	43	902 	URI	D	S	1
FT	#HET	512	 534 	TYR	C	22	1 	NAG	L	S	1
FT	#HET	512	 534 	TYR	C	26	2 	NAG	M	S	1
FT	#HET	514	 536 	ASP	C	22	1 	NAG	L	S	8
FT	#HET	521	 543 	ASP	C	43	902 	URI	D	S	5
FT	#HET	523	 545 	ASP	C	43	902 	URI	D	S	7
FT	#HET	538	 560 	ASP	C	25	1 	NAG	M	S	8
FT	#HET	540	 562 	SER	C	25	1 	NAG	M	S	4
FT	#HET	548	 570 	ILE	C	45	904 	UPT	D	S	1
FT	#HET	549	 571 	ALA	C	45	904 	UPT	D	A	3
FT	#HET	550	 572 	GLY	C	45	904 	UPT	D	B	4
FT	#HET	551	 573 	VAL	C	43	902 	URI	D	A	3
FT	#HET	552	 574 	THR	C	43	902 	URI	D	A	8
FT	#HET	566	 588 	VAL	C	25	1 	NAG	M	S	1
FT	#HET	590	 612 	GLU	C	25	1 	NAG	M	S	6
FT	#HET	592	 614 	VAL	C	25	1 	NAG	M	S	3
FT	#MOD	271	 293 	ASN	C	17	1 	NAG	K	S
FT	#MOD	489	 511 	ASN	C	22	1 	NAG	L	S
FT	#MOD	568	 590 	ASN	C	25	1 	NAG	M	S
FT	DISORDER	1	9
FT	DISORDER	20	22
FT	DISORDER	79	90
FT	DISORDER	411	435
FT	DISORDER	796	811
CC	SEQUENCE	746 AA (ATOM);
CC	RSYPCDEKKQ VIAECSNRRL QEVPQTVGKY VTELDLSDNF ITHITNESFQ GLQNLTKINL
CC	NHNPNVGLNI TDGAFLNLKN LRELLLEDNQ LPQIPSGLPE SLTELSLIQN NIYNITKEGI
CC	SRLINLKNLY LAWNCYFNKV CEKTNIEDGV FETLTNLELL SLSFNSLSHV PPKLPSSLRK
CC	LFLSNTQIKY ISEEDFKGLI NLTLLDLSGN CPRCFNAPFP CVPCDGGASI NIDRFAFQNL
CC	TQLRYLNLSS TSLRKINAAW FKNMPHLKVL DLEFNYLVGE IASGAFLTML PRLEILDLSF
CC	NYIKGSYPQH INISRNFSKL LSLRALHLRG YVFQELREDD FQPLMQLPNL STINLGINFI
CC	KQIDFKLFQN FSNLEIIYLS ENRISPDFEF DPHSNFYHFT RPLIKPQCAA YGKALDLSLN
CC	SIFFIGPNQF ENLPDIACLN LSANSNAQVL SGTEFSAIPH VKYLDLTNNR LDFDNASALT
CC	ELSDLEVLDL SYNSHYFRIA GVTHHLEFIQ NFTNLKVLNL SHNNIYTLTD KYNLESKSLV
CC	ELVFSGNRLD ILWNDDDNRY ISIFKGLKNL TRLDLSLNRL KHIPNEAFLN LPASLTELHI
CC	NDNMLKFFNW TLLQQFPRLE LLDLRGNKLL FLTDSLSDFT SSLRTLLLSH NRISHLPSGF
CC	LSEVSSLKHL DLSSNLLKTI NKSALETKTT TKLSMLELHG NPFECTCDIG DFRRWMDEHL
CC	NVKIPRLVDV ICASPGDQRG KSIVSL
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES RSPWEENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSD
CC	ATOM   ---------RSYPCDEKKQ---VIAECSNRRLQEVPQTVGKYVTELDLSD
CC	                **********   ****************************
CC	SEQRES NFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFL
CC	ATOM   NFITHITNESFQGLQNLTKINLNHNPNV------------GLNITDGAFL
CC	       ****************************            **********
CC	SEQRES NLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINL
CC	ATOM   NLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINL
CC	       **************************************************
CC	SEQRES KNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS
CC	ATOM   KNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS
CC	       **************************************************
CC	SEQRES SLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDG
CC	ATOM   SLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDG
CC	       **************************************************
CC	SEQRES GASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNY
CC	ATOM   GASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNY
CC	       **************************************************
CC	SEQRES LVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRAL
CC	ATOM   LVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRAL
CC	       **************************************************
CC	SEQRES HLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEI
CC	ATOM   HLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEI
CC	       **************************************************
CC	SEQRES IYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTR
CC	ATOM   IYLSENRISP-------------------------DFEFDPHSNFYHFTR
CC	       **********                         ***************
CC	SEQRES PLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLS
CC	ATOM   PLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLS
CC	       **************************************************
CC	SEQRES GTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAG
CC	ATOM   GTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAG
CC	       **************************************************
CC	SEQRES VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI
CC	ATOM   VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI
CC	       **************************************************
CC	SEQRES LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHIN
CC	ATOM   LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHIN
CC	       **************************************************
CC	SEQRES DNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHN
CC	ATOM   DNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHN
CC	       **************************************************
CC	SEQRES RISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN
CC	ATOM   RISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN
CC	       **************************************************
CC	SEQRES PFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTC
CC	ATOM   PFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSL-----
CC	       *********************************************     
CC	SEQRES VSDVTEFLVPR
CC	ATOM   -----------
CC	                  
SQ	SEQUENCE	811 AA;      MW;         CN;
	RSPWEENFSR SYPCDEKKQN DSVIAECSNR RLQEVPQTVG KYVTELDLSD NFITHITNES
	FQGLQNLTKI NLNHNPNVQH QNGNPGIQSN GLNITDGAFL NLKNLRELLL EDNQLPQIPS
	GLPESLTELS LIQNNIYNIT KEGISRLINL KNLYLAWNCY FNKVCEKTNI EDGVFETLTN
	LELLSLSFNS LSHVPPKLPS SLRKLFLSNT QIKYISEEDF KGLINLTLLD LSGNCPRCFN
	APFPCVPCDG GASINIDRFA FQNLTQLRYL NLSSTSLRKI NAAWFKNMPH LKVLDLEFNY
	LVGEIASGAF LTMLPRLEIL DLSFNYIKGS YPQHINISRN FSKLLSLRAL HLRGYVFQEL
	REDDFQPLMQ LPNLSTINLG INFIKQIDFK LFQNFSNLEI IYLSENRISP LVKDTRQSYA
	NSSSFQRHIR KRRSTDFEFD PHSNFYHFTR PLIKPQCAAY GKALDLSLNS IFFIGPNQFE
	NLPDIACLNL SANSNAQVLS GTEFSAIPHV KYLDLTNNRL DFDNASALTE LSDLEVLDLS
	YNSHYFRIAG VTHHLEFIQN FTNLKVLNLS HNNIYTLTDK YNLESKSLVE LVFSGNRLDI
	LWNDDDNRYI SIFKGLKNLT RLDLSLNRLK HIPNEAFLNL PASLTELHIN DNMLKFFNWT
	LLQQFPRLEL LDLRGNKLLF LTDSLSDFTS SLRTLLLSHN RISHLPSGFL SEVSSLKHLD
	LSSNLLKTIN KSALETKTTT KLSMLELHGN PFECTCDIGD FRRWMDEHLN VKIPRLVDVI
	CASPGDQRGK SIVSLELTTC VSDVTEFLVP R
//
ID	4R09D	STANDARD;	PRT;	811	AA.
DT	CONVERTED FROM PDB (SEQRES) 4R09
DE	Toll-like receptor 8
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.620
CC	R-Factor	0.220
FT	#SUB	160	 182 	TYR	D	605	 627 	ASP	C	Protein	S	5
FT	#SUB	161	 183 	PHE	D	605	 627 	ASP	C	Protein	S	1
FT	#SUB	162	 184 	ASN	D	605	 627 	ASP	C	Protein	A	4
FT	#SUB	162	 184 	ASN	D	606	 628 	ASP	C	Protein	S	3
FT	#SUB	162	 184 	ASN	D	607	 629 	ASN	C	Protein	S	8
FT	#SUB	163	 185 	LYS	D	605	 627 	ASP	C	Protein	S	2
FT	#SUB	239	 261 	PHE	D	578	 600 	THR	C	Protein	S	2
FT	#SUB	240	 262 	ASN	D	549	 571 	ALA	C	Protein	S	1
FT	#SUB	240	 262 	ASN	D	550	 572 	GLY	C	Protein	S	2
FT	#SUB	240	 262 	ASN	D	551	 573 	VAL	C	Protein	S	6
FT	#SUB	240	 262 	ASN	D	552	 574 	THR	C	Protein	S	1
FT	#SUB	240	 262 	ASN	D	578	 600 	THR	C	Protein	S	4
FT	#SUB	241	 263 	ALA	D	608	 630 	ARG	C	Protein	B	1
FT	#SUB	242	 264 	PRO	D	576	 598 	THR	C	Protein	B	1
FT	#SUB	242	 264 	PRO	D	608	 630 	ARG	C	Protein	B	2
FT	#SUB	243	 265 	PHE	D	608	 630 	ARG	C	Protein	B	11
FT	#SUB	244	 266 	PRO	D	605	 627 	ASP	C	Protein	S	1
FT	#SUB	244	 266 	PRO	D	606	 628 	ASP	C	Protein	S	5
FT	#SUB	244	 266 	PRO	D	608	 630 	ARG	C	Protein	A	6
FT	#SUB	324	 346 	PHE	D	550	 572 	GLY	C	Protein	S	4
FT	#SUB	326	 348 	TYR	D	550	 572 	GLY	C	Protein	S	1
FT	#SUB	381	 403 	ILE	D	551	 573 	VAL	C	Protein	S	1
FT	#SUB	383	 405 	PHE	D	521	 543 	ASP	C	Protein	S	2
FT	#SUB	383	 405 	PHE	D	545	 567 	TYR	C	Protein	S	1
FT	#SUB	383	 405 	PHE	D	551	 573 	VAL	C	Protein	S	1
FT	#SUB	405	 427 	GLU	D	544	 566 	HIS	C	Protein	S	6
FT	#SUB	405	 427 	GLU	D	545	 567 	TYR	C	Protein	S	2
FT	#SUB	405	 427 	GLU	D	548	 570 	ILE	C	Protein	S	3
FT	#SUB	407	 429 	ARG	D	496	 518 	ALA	C	Protein	S	5
FT	#SUB	407	 429 	ARG	D	498	 520 	VAL	C	Protein	S	1
FT	#SUB	407	 429 	ARG	D	521	 543 	ASP	C	Protein	S	3
FT	#SUB	409	 431 	SER	D	472	 494 	PHE	C	Protein	S	2
FT	#SUB	438	 460 	GLU	D	600	 622 	ILE	C	Protein	S	2
FT	#SUB	438	 460 	GLU	D	603	 625 	ASN	C	Protein	A	2
FT	#SUB	468	 490 	LEU	D	544	 566 	HIS	C	Protein	S	2
FT	#SUB	469	 491 	ASN	D	519	 541 	ARG	C	Protein	B	5
FT	#SUB	470	 492 	SER	D	472	 494 	PHE	C	Protein	S	3
FT	#SUB	472	 494 	PHE	D	409	 431 	SER	C	Protein	S	2
FT	#SUB	472	 494 	PHE	D	470	 492 	SER	C	Protein	S	3
FT	#SUB	472	 494 	PHE	D	472	 494 	PHE	C	Protein	S	4
FT	#SUB	492	 514 	ALA	D	519	 541 	ARG	C	Protein	B	4
FT	#SUB	494	 516 	SER	D	494	 516 	SER	C	Protein	S	4
FT	#SUB	496	 518 	ALA	D	407	 429 	ARG	C	Protein	B	3
FT	#SUB	497	 519 	GLN	D	407	 429 	ARG	C	Protein	B	3
FT	#SUB	519	 541 	ARG	D	468	 490 	LEU	C	Protein	S	1
FT	#SUB	519	 541 	ARG	D	469	 491 	ASN	C	Protein	S	4
FT	#SUB	519	 541 	ARG	D	492	 514 	ALA	C	Protein	S	4
FT	#SUB	521	 543 	ASP	D	383	 405 	PHE	C	Protein	S	2
FT	#SUB	521	 543 	ASP	D	407	 429 	ARG	C	Protein	S	2
FT	#SUB	544	 566 	HIS	D	405	 427 	GLU	C	Protein	S	6
FT	#SUB	544	 566 	HIS	D	468	 490 	LEU	C	Protein	S	2
FT	#SUB	545	 567 	TYR	D	383	 405 	PHE	C	Protein	S	1
FT	#SUB	545	 567 	TYR	D	405	 427 	GLU	C	Protein	S	1
FT	#SUB	545	 567 	TYR	D	407	 429 	ARG	C	Protein	S	1
FT	#SUB	548	 570 	ILE	D	405	 427 	GLU	C	Protein	S	3
FT	#SUB	549	 571 	ALA	D	240	 262 	ASN	C	Protein	B	1
FT	#SUB	550	 572 	GLY	D	240	 262 	ASN	C	Protein	B	2
FT	#SUB	550	 572 	GLY	D	324	 346 	PHE	C	Protein	B	4
FT	#SUB	550	 572 	GLY	D	326	 348 	TYR	C	Protein	B	1
FT	#SUB	551	 573 	VAL	D	240	 262 	ASN	C	Protein	B	5
FT	#SUB	551	 573 	VAL	D	381	 403 	ILE	C	Protein	S	1
FT	#SUB	551	 573 	VAL	D	383	 405 	PHE	C	Protein	S	2
FT	#SUB	552	 574 	THR	D	239	 261 	PHE	C	Protein	S	1
FT	#SUB	552	 574 	THR	D	240	 262 	ASN	C	Protein	B	2
FT	#SUB	578	 600 	THR	D	239	 261 	PHE	C	Protein	S	2
FT	#SUB	578	 600 	THR	D	240	 262 	ASN	C	Protein	A	5
FT	#SUB	579	 601 	ASP	D	239	 261 	PHE	C	Protein	S	2
FT	#SUB	600	 622 	ILE	D	438	 460 	GLU	C	Protein	S	4
FT	#SUB	603	 625 	ASN	D	436	 458 	ASP	C	Protein	S	1
FT	#SUB	605	 627 	ASP	D	160	 182 	TYR	C	Protein	S	5
FT	#SUB	605	 627 	ASP	D	161	 183 	PHE	C	Protein	B	2
FT	#SUB	605	 627 	ASP	D	162	 184 	ASN	C	Protein	B	7
FT	#SUB	605	 627 	ASP	D	244	 266 	PRO	C	Protein	B	1
FT	#SUB	606	 628 	ASP	D	162	 184 	ASN	C	Protein	B	2
FT	#SUB	606	 628 	ASP	D	244	 266 	PRO	C	Protein	S	3
FT	#SUB	607	 629 	ASN	D	162	 184 	ASN	C	Protein	A	8
FT	#SUB	608	 630 	ARG	D	241	 263 	ALA	C	Protein	S	3
FT	#SUB	608	 630 	ARG	D	242	 264 	PRO	C	Protein	S	2
FT	#SUB	608	 630 	ARG	D	243	 265 	PHE	C	Protein	S	8
FT	#SUB	608	 630 	ARG	D	244	 266 	PRO	C	Protein	S	4
FT	#SUB	631	 653 	HIS	D	436	 458 	ASP	C	Protein	S	1
FT	#HET	204	 226 	LYS	D	28	2 	NAG	N	S	3
FT	#HET	206	 228 	PHE	D	27	1 	NAG	N	S	3
FT	#HET	208	 230 	SER	D	27	1 	NAG	N	S	2
FT	#HET	228	 250 	LEU	D	27	1 	NAG	N	S	2
FT	#HET	228	 250 	LEU	D	28	2 	NAG	N	S	4
FT	#HET	230	 252 	ASP	D	27	1 	NAG	N	S	11
FT	#HET	232	 254 	SER	D	27	1 	NAG	N	S	3
FT	#HET	242	 264 	PRO	D	45	904 	UPT	D	S	5
FT	#HET	243	 265 	PHE	D	45	904 	UPT	D	S	3
FT	#HET	269	 291 	TYR	D	28	2 	NAG	N	S	7
FT	#HET	269	 291 	TYR	D	44	903 	06S	D	S	5
FT	#HET	292	 314 	LYS	D	44	903 	06S	D	S	2
FT	#HET	293	 315 	VAL	D	44	903 	06S	D	S	3
FT	#HET	298	 320 	PHE	D	45	904 	UPT	D	S	20
FT	#HET	319	 341 	ILE	D	44	903 	06S	D	S	2
FT	#HET	321	 343 	ASP	D	44	903 	06S	D	S	5
FT	#HET	324	 346 	PHE	D	45	904 	UPT	D	S	5
FT	#HET	326	 348 	TYR	D	43	902 	URI	D	S	6
FT	#HET	329	 351 	GLY	D	43	902 	URI	D	B	3
FT	#HET	330	 352 	SER	D	43	902 	URI	D	B	1
FT	#HET	331	 353 	TYR	D	43	902 	URI	D	S	8
FT	#HET	351	 373 	HIS	D	44	903 	06S	D	S	25
FT	#HET	353	 375 	ARG	D	44	903 	06S	D	S	4
FT	#HET	353	 375 	ARG	D	45	904 	UPT	D	S	8
FT	#HET	356	 378 	VAL	D	43	902 	URI	D	S	4
FT	#HET	378	 400 	ASN	D	44	903 	06S	D	S	1
FT	#HET	381	 403 	ILE	D	45	904 	UPT	D	S	2
FT	#HET	383	 405 	PHE	D	43	902 	URI	D	S	26
FT	#HET	407	 429 	ARG	D	43	902 	URI	D	S	5
FT	#HET	442	 464 	HIS	D	28	2 	NAG	N	B	4
FT	#HET	442	 464 	HIS	D	29	3 	BMA	N	B	1
FT	#HET	443	 465 	SER	D	28	2 	NAG	N	B	2
FT	#HET	444	 466 	ASN	D	27	1 	NAG	N	A	4
FT	#HET	444	 466 	ASN	D	28	2 	NAG	N	B	1
FT	#HET	444	 466 	ASN	D	44	903 	06S	D	S	1
FT	#HET	445	 467 	PHE	D	27	1 	NAG	N	A	5
FT	#HET	445	 467 	PHE	D	45	904 	UPT	D	B	4
FT	#HET	446	 468 	TYR	D	27	1 	NAG	N	S	1
FT	#HET	446	 468 	TYR	D	45	904 	UPT	D	A	4
FT	#HET	447	 469 	HIS	D	44	903 	06S	D	S	26
FT	#HET	447	 469 	HIS	D	45	904 	UPT	D	B	1
FT	#HET	448	 470 	PHE	D	44	903 	06S	D	B	5
FT	#HET	448	 470 	PHE	D	45	904 	UPT	D	S	3
FT	#HET	449	 471 	THR	D	44	903 	06S	D	A	9
FT	#HET	450	 472 	ARG	D	44	903 	06S	D	B	3
FT	#HET	452	 474 	LEU	D	44	903 	06S	D	S	3
FT	#HET	453	 475 	ILE	D	46	908 	NAG	D	A	2
FT	#HET	454	 476 	LYS	D	46	908 	NAG	D	A	2
FT	#HET	456	 478 	GLN	D	31	2 	NAG	O	S	10
FT	#HET	457	 479 	CYS	D	46	908 	NAG	D	S	1
FT	#HET	465	 487 	ASP	D	46	908 	NAG	D	S	2
FT	#HET	467	 489 	SER	D	46	908 	NAG	D	S	6
FT	#HET	468	 490 	LEU	D	46	908 	NAG	D	S	2
FT	#HET	491	 513 	SER	D	46	908 	NAG	D	S	2
FT	#HET	498	 520 	VAL	D	42	901 	URI	D	S	1
FT	#HET	512	 534 	TYR	D	31	2 	NAG	O	S	4
FT	#HET	512	 534 	TYR	D	46	908 	NAG	D	S	1
FT	#HET	514	 536 	ASP	D	46	908 	NAG	D	S	7
FT	#HET	521	 543 	ASP	D	42	901 	URI	D	S	6
FT	#HET	523	 545 	ASP	D	42	901 	URI	D	S	12
FT	#HET	536	 558 	VAL	D	31	2 	NAG	O	S	1
FT	#HET	538	 560 	ASP	D	30	1 	NAG	O	S	10
FT	#HET	540	 562 	SER	D	30	1 	NAG	O	S	5
FT	#HET	548	 570 	ILE	D	41	902 	UPT	C	S	1
FT	#HET	549	 571 	ALA	D	41	902 	UPT	C	A	5
FT	#HET	550	 572 	GLY	D	41	902 	UPT	C	B	4
FT	#HET	551	 573 	VAL	D	42	901 	URI	D	A	5
FT	#HET	552	 574 	THR	D	42	901 	URI	D	A	4
FT	#HET	566	 588 	VAL	D	30	1 	NAG	O	S	1
FT	#HET	590	 612 	GLU	D	30	1 	NAG	O	S	6
FT	#HET	592	 614 	VAL	D	30	1 	NAG	O	S	2
FT	#MOD	271	 293 	ASN	D	27	1 	NAG	N	S
FT	#MOD	489	 511 	ASN	D	46	908 	NAG	D	S
FT	#MOD	568	 590 	ASN	D	30	1 	NAG	O	S
FT	DISORDER	1	9
FT	DISORDER	20	22
FT	DISORDER	78	89
FT	DISORDER	412	435
FT	DISORDER	795	811
CC	SEQUENCE	746 AA (ATOM);
CC	RSYPCDEKKQ VIAECSNRRL QEVPQTVGKY VTELDLSDNF ITHITNESFQ GLQNLTKINL
CC	NHNPNNGLNI TDGAFLNLKN LRELLLEDNQ LPQIPSGLPE SLTELSLIQN NIYNITKEGI
CC	SRLINLKNLY LAWNCYFNKV CEKTNIEDGV FETLTNLELL SLSFNSLSHV PPKLPSSLRK
CC	LFLSNTQIKY ISEEDFKGLI NLTLLDLSGN CPRCFNAPFP CVPCDGGASI NIDRFAFQNL
CC	TQLRYLNLSS TSLRKINAAW FKNMPHLKVL DLEFNYLVGE IASGAFLTML PRLEILDLSF
CC	NYIKGSYPQH INISRNFSKL LSLRALHLRG YVFQELREDD FQPLMQLPNL STINLGINFI
CC	KQIDFKLFQN FSNLEIIYLS ENRISPLDFE FDPHSNFYHF TRPLIKPQCA AYGKALDLSL
CC	NSIFFIGPNQ FENLPDIACL NLSANSNAQV LSGTEFSAIP HVKYLDLTNN RLDFDNASAL
CC	TELSDLEVLD LSYNSHYFRI AGVTHHLEFI QNFTNLKVLN LSHNNIYTLT DKYNLESKSL
CC	VELVFSGNRL DILWNDDDNR YISIFKGLKN LTRLDLSLNR LKHIPNEAFL NLPASLTELH
CC	INDNMLKFFN WTLLQQFPRL ELLDLRGNKL LFLTDSLSDF TSSLRTLLLS HNRISHLPSG
CC	FLSEVSSLKH LDLSSNLLKT INKSALETKT TTKLSMLELH GNPFECTCDI GDFRRWMDEH
CC	LNVKIPRLVD VICASPGDQR GKSIVS
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES RSPWEENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSD
CC	ATOM   ---------RSYPCDEKKQ---VIAECSNRRLQEVPQTVGKYVTELDLSD
CC	                **********   ****************************
CC	SEQRES NFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFL
CC	ATOM   NFITHITNESFQGLQNLTKINLNHNPN------------NGLNITDGAFL
CC	       ***************************            ***********
CC	SEQRES NLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINL
CC	ATOM   NLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINL
CC	       **************************************************
CC	SEQRES KNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS
CC	ATOM   KNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS
CC	       **************************************************
CC	SEQRES SLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDG
CC	ATOM   SLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDG
CC	       **************************************************
CC	SEQRES GASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNY
CC	ATOM   GASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNY
CC	       **************************************************
CC	SEQRES LVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRAL
CC	ATOM   LVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRAL
CC	       **************************************************
CC	SEQRES HLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEI
CC	ATOM   HLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEI
CC	       **************************************************
CC	SEQRES IYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTR
CC	ATOM   IYLSENRISPL------------------------DFEFDPHSNFYHFTR
CC	       ***********                        ***************
CC	SEQRES PLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLS
CC	ATOM   PLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLS
CC	       **************************************************
CC	SEQRES GTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAG
CC	ATOM   GTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAG
CC	       **************************************************
CC	SEQRES VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI
CC	ATOM   VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI
CC	       **************************************************
CC	SEQRES LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHIN
CC	ATOM   LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHIN
CC	       **************************************************
CC	SEQRES DNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHN
CC	ATOM   DNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHN
CC	       **************************************************
CC	SEQRES RISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN
CC	ATOM   RISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN
CC	       **************************************************
CC	SEQRES PFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTC
CC	ATOM   PFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVS------
CC	       ********************************************      
CC	SEQRES VSDVTEFLVPR
CC	ATOM   -----------
CC	                  
SQ	SEQUENCE	811 AA;      MW;         CN;
	RSPWEENFSR SYPCDEKKQN DSVIAECSNR RLQEVPQTVG KYVTELDLSD NFITHITNES
	FQGLQNLTKI NLNHNPNVQH QNGNPGIQSN GLNITDGAFL NLKNLRELLL EDNQLPQIPS
	GLPESLTELS LIQNNIYNIT KEGISRLINL KNLYLAWNCY FNKVCEKTNI EDGVFETLTN
	LELLSLSFNS LSHVPPKLPS SLRKLFLSNT QIKYISEEDF KGLINLTLLD LSGNCPRCFN
	APFPCVPCDG GASINIDRFA FQNLTQLRYL NLSSTSLRKI NAAWFKNMPH LKVLDLEFNY
	LVGEIASGAF LTMLPRLEIL DLSFNYIKGS YPQHINISRN FSKLLSLRAL HLRGYVFQEL
	REDDFQPLMQ LPNLSTINLG INFIKQIDFK LFQNFSNLEI IYLSENRISP LVKDTRQSYA
	NSSSFQRHIR KRRSTDFEFD PHSNFYHFTR PLIKPQCAAY GKALDLSLNS IFFIGPNQFE
	NLPDIACLNL SANSNAQVLS GTEFSAIPHV KYLDLTNNRL DFDNASALTE LSDLEVLDLS
	YNSHYFRIAG VTHHLEFIQN FTNLKVLNLS HNNIYTLTDK YNLESKSLVE LVFSGNRLDI
	LWNDDDNRYI SIFKGLKNLT RLDLSLNRLK HIPNEAFLNL PASLTELHIN DNMLKFFNWT
	LLQQFPRLEL LDLRGNKLLF LTDSLSDFTS SLRTLLLSHN RISHLPSGFL SEVSSLKHLD
	LSSNLLKTIN KSALETKTTT KLSMLELHGN PFECTCDIGD FRRWMDEHLN VKIPRLVDVI
	CASPGDQRGK SIVSLELTTC VSDVTEFLVP R
//