ID	4QHVA	STANDARD;	PRT;	186	AA.
DT	CONVERTED FROM PDB (SEQRES) 4QHV
DE	Dihydrofolate reductase
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.610
CC	R-Factor	0.179
FT	#HET	4	   4 	LEU	A	5	205 	SO4	A	S	2
FT	#HET	7	   7 	ILE	A	2	202 	IXF	A	A	7
FT	#HET	8	   8 	VAL	A	1	201 	NDP	A	A	5
FT	#HET	8	   8 	VAL	A	2	202 	IXF	A	B	8
FT	#HET	9	   9 	ALA	A	1	201 	NDP	A	B	7
FT	#HET	9	   9 	ALA	A	2	202 	IXF	A	A	5
FT	#HET	16	  16 	ILE	A	1	201 	NDP	A	A	12
FT	#HET	17	  17 	GLY	A	1	201 	NDP	A	B	4
FT	#HET	18	  18 	LYS	A	1	201 	NDP	A	B	1
FT	#HET	20	  20 	GLY	A	1	201 	NDP	A	B	7
FT	#HET	21	  21 	ASP	A	1	201 	NDP	A	B	6
FT	#HET	22	  22 	LEU	A	1	201 	NDP	A	S	4
FT	#HET	22	  22 	LEU	A	2	202 	IXF	A	S	2
FT	#HET	24	  24 	TRP	A	1	201 	NDP	A	S	2
FT	#HET	30	  30 	GLU	A	2	202 	IXF	A	S	10
FT	#HET	31	  31 	PHE	A	2	202 	IXF	A	S	4
FT	#HET	34	  34 	PHE	A	2	202 	IXF	A	S	11
FT	#HET	53	  53 	GLY	A	1	201 	NDP	A	B	9
FT	#HET	53	  53 	GLY	A	7	207 	SO4	A	B	9
FT	#HET	54	  54 	LYS	A	1	201 	NDP	A	A	13
FT	#HET	54	  54 	LYS	A	7	207 	SO4	A	B	2
FT	#HET	54	  54 	LYS	A	8	208 	SO4	A	S	5
FT	#HET	55	  55 	LYS	A	1	201 	NDP	A	A	27
FT	#HET	55	  55 	LYS	A	7	207 	SO4	A	A	16
FT	#HET	56	  56 	THR	A	1	201 	NDP	A	A	11
FT	#HET	56	  56 	THR	A	7	207 	SO4	A	A	6
FT	#HET	59	  59 	SER	A	1	201 	NDP	A	S	2
FT	#HET	59	  59 	SER	A	2	202 	IXF	A	S	1
FT	#HET	60	  60 	ILE	A	6	206 	SO4	A	B	1
FT	#HET	61	  61 	PRO	A	2	202 	IXF	A	S	1
FT	#HET	61	  61 	PRO	A	6	206 	SO4	A	B	2
FT	#HET	62	  62 	GLU	A	6	206 	SO4	A	A	5
FT	#HET	64	  64 	ASN	A	2	202 	IXF	A	S	3
FT	#HET	65	  65 	ARG	A	6	206 	SO4	A	S	1
FT	#HET	67	  67 	LEU	A	2	202 	IXF	A	S	1
FT	#HET	75	  75 	LEU	A	1	201 	NDP	A	A	15
FT	#HET	76	  76 	SER	A	1	201 	NDP	A	A	11
FT	#HET	76	  76 	SER	A	8	208 	SO4	A	A	7
FT	#HET	77	  77 	ARG	A	1	201 	NDP	A	A	9
FT	#HET	77	  77 	ARG	A	8	208 	SO4	A	A	5
FT	#HET	78	  78 	GLU	A	1	201 	NDP	A	A	5
FT	#HET	78	  78 	GLU	A	8	208 	SO4	A	A	9
FT	#HET	91	  91 	ARG	A	1	201 	NDP	A	B	5
FT	#HET	92	  92 	SER	A	1	201 	NDP	A	B	3
FT	#HET	93	  93 	LEU	A	1	201 	NDP	A	B	1
FT	#HET	94	  94 	ASP	A	5	205 	SO4	A	S	1
FT	#HET	97	  97 	LEU	A	5	205 	SO4	A	S	4
FT	#HET	115	 115 	VAL	A	1	201 	NDP	A	B	3
FT	#HET	115	 115 	VAL	A	2	202 	IXF	A	B	1
FT	#HET	116	 116 	GLY	A	1	201 	NDP	A	B	1
FT	#HET	117	 117 	GLY	A	1	201 	NDP	A	B	8
FT	#HET	117	 117 	GLY	A	7	207 	SO4	A	B	8
FT	#HET	118	 118 	SER	A	1	201 	NDP	A	A	3
FT	#HET	119	 119 	SER	A	1	201 	NDP	A	S	3
FT	#HET	120	 120 	VAL	A	1	201 	NDP	A	S	3
FT	#HET	120	 120 	VAL	A	7	207 	SO4	A	S	1
FT	#HET	121	 121 	TYR	A	1	201 	NDP	A	S	3
FT	#HET	121	 121 	TYR	A	2	202 	IXF	A	S	1
FT	#HET	123	 123 	GLU	A	1	201 	NDP	A	S	1
FT	#HET	127	 127 	HIS	A	5	205 	SO4	A	A	20
FT	#HET	128	 128 	PRO	A	5	205 	SO4	A	B	1
FT	#HET	136	 136 	THR	A	2	202 	IXF	A	S	1
FT	#HET	146	 146 	THR	A	1	201 	NDP	A	S	4
FT	#HET	165	 165 	VAL	A	3	203 	SO4	A	B	1
FT	#HET	166	 166 	LEU	A	3	203 	SO4	A	B	2
FT	#HET	167	 167 	SER	A	3	203 	SO4	A	A	5
FT	#HET	168	 168 	ASP	A	3	203 	SO4	A	A	2
FT	#HET	172	 172 	GLU	A	4	204 	SO4	A	A	3
FT	#HET	173	 173 	LYS	A	4	204 	SO4	A	A	8
CC	SEQUENCE	186 AA (ATOM);
CC	VGSLNCIVAV SQNMGIGKNG DLPWPPLRNE FRYFQRMTTT SSVEGKQNLV IMGKKTWFSI
CC	PEKNRPLKGR INLVLSRELK EPPQGAHFLS RSLDDALKLT EQPELANKVD MVWIVGGSSV
CC	YKEAMNHPGH LKLFVTRIMQ DFESDTFFPE IDLEKYKLLP EYPGVLSDVQ EEKGIKYKFE
CC	VYEKND
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLV
CC	ATOM   VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLV
CC	       **************************************************
CC	SEQRES IMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLT
CC	ATOM   IMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLT
CC	       **************************************************
CC	SEQRES EQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPE
CC	ATOM   EQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPE
CC	       **************************************************
CC	SEQRES IDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
CC	ATOM   IDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
CC	       ************************************
SQ	SEQUENCE	186 AA;      MW;         CN;
	VGSLNCIVAV SQNMGIGKNG DLPWPPLRNE FRYFQRMTTT SSVEGKQNLV IMGKKTWFSI
	PEKNRPLKGR INLVLSRELK EPPQGAHFLS RSLDDALKLT EQPELANKVD MVWIVGGSSV
	YKEAMNHPGH LKLFVTRIMQ DFESDTFFPE IDLEKYKLLP EYPGVLSDVQ EEKGIKYKFE
	VYEKND
//