ID	4L78A	STANDARD;	PRT;	1303	AA.
DT	CONVERTED FROM PDB (SEQRES) 4L78
DE	Phosphoribosylformylglycinamidine synthase
OS	Salmonella typhimurium
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.180
CC	R-Factor	0.140
FT	#HET	11	   3 	GLU	A	23	1323 	XE	A	B	1
FT	#HET	13	   5 	LEU	A	23	1323 	XE	A	A	5
FT	#HET	20	  12 	SER	A	15	1315 	SO4	A	S	2
FT	#HET	21	  13 	ALA	A	15	1315 	SO4	A	A	5
FT	#HET	22	  14 	PHE	A	15	1315 	SO4	A	A	7
FT	#HET	30	  22 	ARG	A	24	1324 	CL	A	A	3
FT	#HET	34	  26 	ALA	A	24	1324 	CL	A	S	1
FT	#HET	47	  39 	HIS	A	23	1323 	XE	A	B	2
FT	#HET	49	  41 	ALA	A	23	1323 	XE	A	A	2
FT	#HET	67	  59 	LEU	A	23	1323 	XE	A	S	1
FT	#HET	76	  68 	HIS	A	28	1328 	ACT	A	S	6
FT	#HET	77	  69 	THR	A	28	1328 	ACT	A	A	3
FT	#HET	138	 130 	GLU	A	24	1324 	CL	A	S	3
FT	#HET	198	 190 	LEU	A	21	1321 	XE	A	S	1
FT	#HET	202	 194 	PHE	A	21	1321 	XE	A	S	2
FT	#HET	215	 207 	TYR	A	26	1326 	CL	A	S	1
FT	#HET	217	 209 	PHE	A	21	1321 	XE	A	S	1
FT	#HET	218	 210 	ALA	A	26	1326 	CL	A	S	1
FT	#HET	219	 211 	GLN	A	26	1326 	CL	A	S	2
FT	#HET	224	 216 	HIS	A	7	1307 	SO4	A	S	4
FT	#HET	224	 216 	HIS	A	8	1308 	SO4	A	S	2
FT	#HET	259	 251 	TYR	A	5	1305 	MG	A	S	2
FT	#HET	302	 294 	GLU	A	7	1307 	SO4	A	S	1
FT	#HET	303	 295 	THR	A	8	1308 	SO4	A	A	7
FT	#HET	304	 296 	HIS	A	8	1308 	SO4	A	B	3
FT	#HET	305	 297 	ASN	A	8	1308 	SO4	A	A	11
FT	#HET	306	 298 	HIS	A	8	1308 	SO4	A	A	3
FT	#HET	306	 298 	HIS	A	25	1325 	CL	A	S	2
FT	#HET	309	 301 	ALA	A	25	1325 	CL	A	S	1
FT	#HET	313	 305 	TRP	A	14	1314 	SO4	A	S	3
FT	#HET	341	 333 	VAL	A	1	1301 	ADP	A	A	4
FT	#HET	343	 335 	PHE	A	1	1301 	ADP	A	S	1
FT	#HET	364	 356 	PRO	A	16	1316 	SO4	A	A	6
FT	#HET	365	 357 	GLU	A	16	1316 	SO4	A	A	11
FT	#HET	366	 358 	ARG	A	16	1316 	SO4	A	A	11
FT	#HET	394	 386 	THR	A	1	1301 	ADP	A	A	4
FT	#HET	395	 387 	GLY	A	1	1301 	ADP	A	B	20
FT	#HET	396	 388 	TYR	A	1	1301 	ADP	A	B	13
FT	#HET	397	 389 	PHE	A	1	1301 	ADP	A	A	2
FT	#HET	425	 417 	ILE	A	20	1320 	XE	A	S	1
FT	#HET	440	 432 	VAL	A	27	1327 	ACT	A	S	1
FT	#HET	512	 504 	GLY	A	7	1307 	SO4	A	B	2
FT	#HET	513	 505 	ALA	A	7	1307 	SO4	A	A	7
FT	#HET	589	 581 	THR	A	27	1327 	ACT	A	A	5
FT	#HET	590	 582 	GLU	A	27	1327 	ACT	A	A	5
FT	#HET	591	 583 	GLU	A	27	1327 	ACT	A	A	5
FT	#HET	608	 600 	LEU	A	21	1321 	XE	A	S	1
FT	#HET	640	 632 	THR	A	17	1317 	SO4	A	A	5
FT	#HET	641	 633 	ILE	A	17	1317 	SO4	A	A	6
FT	#HET	657	 649 	LYS	A	1	1301 	ADP	A	S	8
FT	#HET	660	 652 	LEU	A	1	1301 	ADP	A	A	7
FT	#HET	661	 653 	VAL	A	1	1301 	ADP	A	S	1
FT	#HET	676	 668 	GLN	A	1	1301 	ADP	A	A	7
FT	#HET	684	 676 	PRO	A	1	1301 	ADP	A	B	4
FT	#HET	686	 678 	ALA	A	1	1301 	ADP	A	B	5
FT	#HET	687	 679 	ASP	A	1	1301 	ADP	A	S	1
FT	#HET	687	 679 	ASP	A	2	1302 	MG	A	S	4
FT	#HET	689	 681 	ALA	A	20	1320 	XE	A	B	2
FT	#HET	691	 683 	THR	A	20	1320 	XE	A	A	3
FT	#HET	701	 693 	GLU	A	20	1320 	XE	A	B	1
FT	#HET	703	 695 	MET	A	20	1320 	XE	A	S	2
FT	#HET	726	 718 	GLU	A	1	1301 	ADP	A	S	1
FT	#HET	726	 718 	GLU	A	3	1303 	MG	A	S	3
FT	#HET	730	 722 	ASN	A	1	1301 	ADP	A	S	4
FT	#HET	730	 722 	ASN	A	2	1302 	MG	A	S	3
FT	#HET	784	 776 	LYS	A	7	1307 	SO4	A	S	4
FT	#HET	786	 778 	SER	A	8	1308 	SO4	A	A	6
FT	#HET	793	 785 	TRP	A	16	1316 	SO4	A	S	1
FT	#HET	841	 833 	LYS	A	6	1306 	MN	A	S	2
FT	#HET	843	 835 	HIS	A	6	1306 	MN	A	S	1
FT	#HET	886	 878 	LYS	A	22	1322 	XE	A	S	2
FT	#HET	892	 884 	ASP	A	1	1301 	ADP	A	S	1
FT	#HET	892	 884 	ASP	A	2	1302 	MG	A	S	3
FT	#HET	894	 886 	SER	A	1	1301 	ADP	A	S	2
FT	#HET	919	 911 	ALA	A	18	1318 	SO4	A	S	4
FT	#HET	946	 938 	ALA	A	22	1322 	XE	A	A	3
FT	#HET	960	 952 	VAL	A	18	1318 	SO4	A	B	1
FT	#HET	961	 953 	HIS	A	18	1318 	SO4	A	A	8
FT	#HET	1006	 998 	ASN	A	15	1315 	SO4	A	S	3
FT	#HET	1048	1040 	PRO	A	11	1311 	SO4	A	A	6
FT	#HET	1049	1041 	LYS	A	11	1311 	SO4	A	A	11
FT	#HET	1068	1060 	PHE	A	19	1319 	XE	A	S	2
FT	#HET	1092	1084 	ASN	A	11	1311 	SO4	A	B	1
FT	#HET	1094	1086 	HIS	A	11	1311 	SO4	A	S	2
FT	#HET	1094	1086 	HIS	A	12	1312 	SO4	A	S	2
FT	#HET	1096	1088 	LEU	A	19	1319 	XE	A	B	1
FT	#HET	1121	1113 	ASN	A	13	1313 	SO4	A	S	3
FT	#HET	1123	1115 	ARG	A	13	1313 	SO4	A	S	12
FT	#HET	1134	1126 	ARG	A	12	1312 	SO4	A	S	13
FT	#HET	1135	1127 	PRO	A	12	1312 	SO4	A	A	7
FT	#HET	1136	1128 	GLN	A	12	1312 	SO4	A	A	8
FT	#HET	1137	1129 	THR	A	12	1312 	SO4	A	B	1
FT	#HET	1138	1130 	LEU	A	19	1319 	XE	A	A	3
FT	#HET	1139	1131 	ALA	A	19	1319 	XE	A	B	1
FT	#HET	1140	1132 	LEU	A	19	1319 	XE	A	B	1
FT	#HET	1167	1159 	ARG	A	14	1314 	SO4	A	S	7
FT	#HET	1169	1161 	HIS	A	15	1315 	SO4	A	S	3
FT	#HET	1172	1164 	ARG	A	14	1314 	SO4	A	S	1
FT	#HET	1184	1176 	GLN	A	10	1310 	SO4	A	S	1
FT	#HET	1191	1183 	GLN	A	10	1310 	SO4	A	A	3
FT	#HET	1192	1184 	GLY	A	10	1310 	SO4	A	B	9
FT	#HET	1193	1185 	MET	A	10	1310 	SO4	A	B	2
FT	#HET	1194	1186 	VAL	A	10	1310 	SO4	A	A	7
FT	#HET	1236	1228 	LYS	A	9	1309 	SO4	A	A	7
FT	#HET	1237	1229 	VAL	A	9	1309 	SO4	A	A	6
FT	DISORDER	456	473
CC	SEQUENCE	1285 AA (ATOM);
CC	GLVPRGSHMM EILRGSPALS AFRINKLLAR FQAANLQVHN IYAEYVHFAD LNAPLNDSEQ
CC	AQLTRLLQYG PALSSHTPAG KLLLVTPRPG TISPWSSKAT DIAHNCGLQQ VDRLERGVAY
CC	YIEASTLTAE QWRQVAAELH DRMMETVFSS LTDAEKLFIH HQPAPVSSVD LLGEGRQALI
CC	DANLRLGLAL AEDEIDYLQE AFTKLGRNPN DIELYMFAQA NSEHCRHKIF NADWIIDGKP
CC	QPKSLFKMIK NTFETTPDYV LSAYKDNAAV MEGSAVGRYF ADHNTGRYDF HQEPAHILMK
CC	VETHNHPTAI SPWPGAATGS GGEIRDEGAT GRGAKPKAGL VGFSVSNLRI PGFEQPWEED
CC	FGKPERIVTA LDIMTEGPLG GAAFNNEFGR PALTGYFRTY EEKVNSHNGE ELRGYHKPIM
CC	LAGGIGNIRA DHVQKGEIVV GAKLIVLGGP AMNIGDFASV QRDNPEMERR CQEVIDRCWQ
CC	LGDANPILFI HDVGAGGLSN AMPELVSDGG RGGKFELRDI LSDEPGMSPL EIWCNESQER
CC	YVLAVAADQL PLFDELCKRE RAPYAVIGDA TEEQHLSLHD NHFDNQPIDL PLDVLLGKTP
CC	KMTRDVQTLK AKGDALNRAD ITIADAVKRV LHLPTVAEKT FLVTIGDRTV TGMVARDQMV
CC	GPWQVPVADC AVTTASLDSY YGEAMSIGER APVALLDFAA SARLAVGEAL TNIAATQIGD
CC	IKRIKLSANW MAAAGHPGED AGLYDAVKAV GEELCPQLGL TIPVGKDSMS MKTRWQEGNE
CC	QREMTSPLSL VISAFARVED VRHTLTPQLS TEDNALLLID LGKGHNALGA TALAQVYRQL
CC	GDKPADVRDV AQLKGFYDAM QALVAARKLL AWHDRSDGGL LVTLAEMAFA GHCGVQVDIA
CC	ALGDDHLAAL FNEELGGVIQ VRAEDRDAVE ALLAQYGLAD CVHYLGQALA GDRFVITAND
CC	QTVFSESRTT LRVWWAETTW QMQRLRDNPQ CADQEHEAKA NDTDPGLNVK LSFDINEDIA
CC	APYIATGARP KVAVLREQGV NSHVEMAAAF HRAGFDAIDV HMSDLLGGRI GLGNFHALVA
CC	CGGFSYGDVL GAGEGWAKSI LFNHRVRDEF ETFFHRPQTL ALGVXNGCQM MSNLRELIPG
CC	SELWPRFVRN HSDRFEARFS LVEVTQSPSL LLQGMVGSQM PIAVSHGEGR VEVRDDAHLA
CC	ALESKGLVAL RYVDNFGKVT ETYPANPNGS PNGITAVTTE NGRVTIMMPH PEAVFRTVAN
CC	SWHPENWGED SPWMRIFRNA RKQLG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GLVPRGSHMMEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFAD
CC	ATOM   GLVPRGSHMMEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFAD
CC	       **************************************************
CC	SEQRES LNAPLNDSEQAQLTRLLQYGPALSSHTPAGKLLLVTPRPGTISPWSSKAT
CC	ATOM   LNAPLNDSEQAQLTRLLQYGPALSSHTPAGKLLLVTPRPGTISPWSSKAT
CC	       **************************************************
CC	SEQRES DIAHNCGLQQVDRLERGVAYYIEASTLTAEQWRQVAAELHDRMMETVFSS
CC	ATOM   DIAHNCGLQQVDRLERGVAYYIEASTLTAEQWRQVAAELHDRMMETVFSS
CC	       **************************************************
CC	SEQRES LTDAEKLFIHHQPAPVSSVDLLGEGRQALIDANLRLGLALAEDEIDYLQE
CC	ATOM   LTDAEKLFIHHQPAPVSSVDLLGEGRQALIDANLRLGLALAEDEIDYLQE
CC	       **************************************************
CC	SEQRES AFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGKPQPKSLFKMIK
CC	ATOM   AFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGKPQPKSLFKMIK
CC	       **************************************************
CC	SEQRES NTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHNTGRYDFHQEPAHILMK
CC	ATOM   NTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHNTGRYDFHQEPAHILMK
CC	       **************************************************
CC	SEQRES VETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRI
CC	ATOM   VETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRI
CC	       **************************************************
CC	SEQRES PGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALTGYFRTY
CC	ATOM   PGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALTGYFRTY
CC	       **************************************************
CC	SEQRES EEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEIVVGAKLIVLGGP
CC	ATOM   EEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEIVVGAKLIVLGGP
CC	       **************************************************
CC	SEQRES AMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLG
CC	ATOM   AMNIG------------------DFASVQRDNPEMERRCQEVIDRCWQLG
CC	       *****                  ***************************
CC	SEQRES DANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLEI
CC	ATOM   DANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLEI
CC	       **************************************************
CC	SEQRES WCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGDATEEQHLSLHDNH
CC	ATOM   WCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGDATEEQHLSLHDNH
CC	       **************************************************
CC	SEQRES FDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGDALNRADITIADAVKRVLH
CC	ATOM   FDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGDALNRADITIADAVKRVLH
CC	       **************************************************
CC	SEQRES LPTVAEKTFLVTIGDRTVTGMVARDQMVGPWQVPVADCAVTTASLDSYYG
CC	ATOM   LPTVAEKTFLVTIGDRTVTGMVARDQMVGPWQVPVADCAVTTASLDSYYG
CC	       **************************************************
CC	SEQRES EAMSIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANWMA
CC	ATOM   EAMSIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANWMA
CC	       **************************************************
CC	SEQRES AAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMSMKTRWQEGNEQR
CC	ATOM   AAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMSMKTRWQEGNEQR
CC	       **************************************************
CC	SEQRES EMTSPLSLVISAFARVEDVRHTLTPQLSTEDNALLLIDLGKGHNALGATA
CC	ATOM   EMTSPLSLVISAFARVEDVRHTLTPQLSTEDNALLLIDLGKGHNALGATA
CC	       **************************************************
CC	SEQRES LAQVYRQLGDKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLLV
CC	ATOM   LAQVYRQLGDKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLLV
CC	       **************************************************
CC	SEQRES TLAEMAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVEAL
CC	ATOM   TLAEMAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVEAL
CC	       **************************************************
CC	SEQRES LAQYGLADCVHYLGQALAGDRFVITANDQTVFSESRTTLRVWWAETTWQM
CC	ATOM   LAQYGLADCVHYLGQALAGDRFVITANDQTVFSESRTTLRVWWAETTWQM
CC	       **************************************************
CC	SEQRES QRLRDNPQCADQEHEAKANDTDPGLNVKLSFDINEDIAAPYIATGARPKV
CC	ATOM   QRLRDNPQCADQEHEAKANDTDPGLNVKLSFDINEDIAAPYIATGARPKV
CC	       **************************************************
CC	SEQRES AVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRIGLGNFHALVACG
CC	ATOM   AVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRIGLGNFHALVACG
CC	       **************************************************
CC	SEQRES GFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVXNGCQMMS
CC	ATOM   GFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVXNGCQMMS
CC	       **************************************************
CC	SEQRES NLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPI
CC	ATOM   NLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPI
CC	       **************************************************
CC	SEQRES AVSHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPN
CC	ATOM   AVSHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPN
CC	       **************************************************
CC	SEQRES GITAVTTENGRVTIMMPHPEAVFRTVANSWHPENWGEDSPWMRIFRNARK
CC	ATOM   GITAVTTENGRVTIMMPHPEAVFRTVANSWHPENWGEDSPWMRIFRNARK
CC	       **************************************************
CC	SEQRES QLG
CC	ATOM   QLG
CC	       ***
SQ	SEQUENCE	1303 AA;      MW;         CN;
	GLVPRGSHMM EILRGSPALS AFRINKLLAR FQAANLQVHN IYAEYVHFAD LNAPLNDSEQ
	AQLTRLLQYG PALSSHTPAG KLLLVTPRPG TISPWSSKAT DIAHNCGLQQ VDRLERGVAY
	YIEASTLTAE QWRQVAAELH DRMMETVFSS LTDAEKLFIH HQPAPVSSVD LLGEGRQALI
	DANLRLGLAL AEDEIDYLQE AFTKLGRNPN DIELYMFAQA NSEHCRHKIF NADWIIDGKP
	QPKSLFKMIK NTFETTPDYV LSAYKDNAAV MEGSAVGRYF ADHNTGRYDF HQEPAHILMK
	VETHNHPTAI SPWPGAATGS GGEIRDEGAT GRGAKPKAGL VGFSVSNLRI PGFEQPWEED
	FGKPERIVTA LDIMTEGPLG GAAFNNEFGR PALTGYFRTY EEKVNSHNGE ELRGYHKPIM
	LAGGIGNIRA DHVQKGEIVV GAKLIVLGGP AMNIGLGGGA ASSMASGQSD ADLDFASVQR
	DNPEMERRCQ EVIDRCWQLG DANPILFIHD VGAGGLSNAM PELVSDGGRG GKFELRDILS
	DEPGMSPLEI WCNESQERYV LAVAADQLPL FDELCKRERA PYAVIGDATE EQHLSLHDNH
	FDNQPIDLPL DVLLGKTPKM TRDVQTLKAK GDALNRADIT IADAVKRVLH LPTVAEKTFL
	VTIGDRTVTG MVARDQMVGP WQVPVADCAV TTASLDSYYG EAMSIGERAP VALLDFAASA
	RLAVGEALTN IAATQIGDIK RIKLSANWMA AAGHPGEDAG LYDAVKAVGE ELCPQLGLTI
	PVGKDSMSMK TRWQEGNEQR EMTSPLSLVI SAFARVEDVR HTLTPQLSTE DNALLLIDLG
	KGHNALGATA LAQVYRQLGD KPADVRDVAQ LKGFYDAMQA LVAARKLLAW HDRSDGGLLV
	TLAEMAFAGH CGVQVDIAAL GDDHLAALFN EELGGVIQVR AEDRDAVEAL LAQYGLADCV
	HYLGQALAGD RFVITANDQT VFSESRTTLR VWWAETTWQM QRLRDNPQCA DQEHEAKAND
	TDPGLNVKLS FDINEDIAAP YIATGARPKV AVLREQGVNS HVEMAAAFHR AGFDAIDVHM
	SDLLGGRIGL GNFHALVACG GFSYGDVLGA GEGWAKSILF NHRVRDEFET FFHRPQTLAL
	GVXNGCQMMS NLRELIPGSE LWPRFVRNHS DRFEARFSLV EVTQSPSLLL QGMVGSQMPI
	AVSHGEGRVE VRDDAHLAAL ESKGLVALRY VDNFGKVTET YPANPNGSPN GITAVTTENG
	RVTIMMPHPE AVFRTVANSW HPENWGEDSP WMRIFRNARK QLG
//