ID	4J8MA	STANDARD;	PRT;	279	AA.
DT	CONVERTED FROM PDB (SEQRES) 4J8M
DE	Aurora kinase A
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.850
CC	R-Factor	0.178
FT	#HET	6	 128 	TRP	A	5	505 	DMS	A	S	1
FT	#HET	17	 139 	LEU	A	1	501 	CJ5	A	A	11
FT	#HET	18	 140 	GLY	A	1	501 	CJ5	A	B	1
FT	#HET	19	 141 	LYS	A	1	501 	CJ5	A	B	1
FT	#HET	20	 142 	GLY	A	1	501 	CJ5	A	B	1
FT	#HET	22	 144 	PHE	A	1	501 	CJ5	A	A	4
FT	#HET	23	 145 	GLY	A	1	501 	CJ5	A	B	11
FT	#HET	24	 146 	ASN	A	1	501 	CJ5	A	B	7
FT	#HET	25	 147 	VAL	A	1	501 	CJ5	A	A	13
FT	#HET	30	 152 	GLU	A	5	505 	DMS	A	S	4
FT	#HET	35	 157 	PHE	A	5	505 	DMS	A	S	6
FT	#HET	38	 160 	ALA	A	1	501 	CJ5	A	S	3
FT	#HET	40	 162 	LYS	A	1	501 	CJ5	A	S	8
FT	#HET	41	 163 	VAL	A	1	501 	CJ5	A	B	1
FT	#HET	42	 164 	LEU	A	1	501 	CJ5	A	S	4
FT	#HET	72	 194 	LEU	A	1	501 	CJ5	A	S	7
FT	#HET	75	 197 	TYR	A	5	505 	DMS	A	A	14
FT	#HET	88	 210 	LEU	A	1	501 	CJ5	A	S	6
FT	#HET	89	 211 	GLU	A	1	501 	CJ5	A	B	6
FT	#HET	90	 212 	TYR	A	1	501 	CJ5	A	A	16
FT	#HET	91	 213 	ALA	A	1	501 	CJ5	A	A	20
FT	#HET	92	 214 	PRO	A	1	501 	CJ5	A	B	2
FT	#HET	94	 216 	GLY	A	1	501 	CJ5	A	B	7
FT	#HET	95	 217 	THR	A	1	501 	CJ5	A	S	2
FT	#HET	98	 220 	ARG	A	3	503 	PO4	A	S	8
FT	#HET	141	 263 	LEU	A	1	501 	CJ5	A	S	13
FT	#HET	151	 273 	ALA	A	1	501 	CJ5	A	S	2
FT	#HET	152	 274 	ASP	A	1	501 	CJ5	A	S	31
FT	#HET	157	 279 	VAL	A	1	501 	CJ5	A	A	7
FT	#HET	158	 280 	HIS	A	1	501 	CJ5	A	B	3
FT	#HET	159	 281 	ALA	A	1	501 	CJ5	A	A	11
FT	#HET	160	 282 	PRO	A	1	501 	CJ5	A	S	13
FT	#HET	166	 288 	THR	A	6	506 	EDO	A	S	1
FT	#HET	167	 289 	LEU	A	4	504 	DMS	A	B	1
FT	#HET	167	 289 	LEU	A	6	506 	EDO	A	B	1
FT	#HET	171	 293 	LEU	A	4	504 	DMS	A	A	12
FT	#HET	171	 293 	LEU	A	6	506 	EDO	A	S	3
FT	#HET	172	 294 	ASP	A	6	506 	EDO	A	S	7
FT	#HET	207	 329 	PHE	A	6	506 	EDO	A	B	1
FT	#HET	208	 330 	GLU	A	2	502 	MG	A	S	1
FT	#HET	208	 330 	GLU	A	6	506 	EDO	A	A	5
FT	#HET	209	 331 	ALA	A	6	506 	EDO	A	B	10
FT	#HET	211	 333 	THR	A	6	506 	EDO	A	B	4
FT	#HET	212	 334 	TYR	A	4	504 	DMS	A	A	8
FT	#HET	212	 334 	TYR	A	6	506 	EDO	A	A	7
FT	#HET	215	 337 	THR	A	6	506 	EDO	A	S	9
FT	#HET	216	 338 	TYR	A	4	504 	DMS	A	S	8
FT	DISORDER	1	2
FT	DISORDER	269	279
CC	SEQUENCE	266 AA (ATOM);
CC	KRQWALEDFE IGRPLGKGKF GNVYLAREKQ SKFILALKVL FKAQLEKAGV EHQLRREVEI
CC	QSHLRHPNIL RLYGYFHDAT RVYLILEYAP LGTVYRELQK LSKFDEQRTA TYITELANAL
CC	SYXHSKRVIH RDIKPENLLL GSAGELKIAD FGWSVHAPSS RRDTLCGTLD YLPPEMIEGR
CC	MHDEKVDLWS LGVLCYEFLV GKPPFEANTY QETYKRISRV EFTFPDFVTE GARDLISRLL
CC	KHNPSQRPML REVLEHPWIT ANSSKP
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES SKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA
CC	ATOM   --KRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA
CC	         ************************************************
CC	SEQRES GVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL
CC	ATOM   GVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL
CC	       **************************************************
CC	SEQRES QKLSKFDEQRTATYITELANALSYXHSKRVIHRDIKPENLLLGSAGELKI
CC	ATOM   QKLSKFDEQRTATYITELANALSYXHSKRVIHRDIKPENLLLGSAGELKI
CC	       **************************************************
CC	SEQRES ADFGWSVHAPSSRRDTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEF
CC	ATOM   ADFGWSVHAPSSRRDTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEF
CC	       **************************************************
CC	SEQRES LVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRP
CC	ATOM   LVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRP
CC	       **************************************************
CC	SEQRES MLREVLEHPWITANSSKPSNCQNKESASK
CC	ATOM   MLREVLEHPWITANSSKP-----------
CC	       ******************           
SQ	SEQUENCE	279 AA;      MW;         CN;
	SKKRQWALED FEIGRPLGKG KFGNVYLARE KQSKFILALK VLFKAQLEKA GVEHQLRREV
	EIQSHLRHPN ILRLYGYFHD ATRVYLILEY APLGTVYREL QKLSKFDEQR TATYITELAN
	ALSYXHSKRV IHRDIKPENL LLGSAGELKI ADFGWSVHAP SSRRDTLCGT LDYLPPEMIE
	GRMHDEKVDL WSLGVLCYEF LVGKPPFEAN TYQETYKRIS RVEFTFPDFV TEGARDLISR
	LLKHNPSQRP MLREVLEHPW ITANSSKPSN CQNKESASK
//