ID	4HZTA	STANDARD;	PRT;	406	AA.
DT	CONVERTED FROM PDB (SEQRES) 4HZT
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.800
CC	R-Factor	0.201
FT	#HET	17	  72 	GLY	A	4	504 	0ZA	A	B	3
FT	#HET	18	  73 	GLN	A	4	504 	0ZA	A	B	7
FT	#HET	19	  74 	GLY	A	4	504 	0ZA	A	B	4
FT	#HET	23	  78 	GLU	A	3	503 	ZN	A	S	3
FT	#HET	36	  91 	LEU	A	4	504 	0ZA	A	S	4
FT	#HET	38	  93 	ASP	A	4	504 	0ZA	A	S	2
FT	#HET	77	 132 	TYR	A	4	504 	0ZA	A	S	14
FT	#HET	79	 134 	GLN	A	4	504 	0ZA	A	S	9
FT	#HET	80	 135 	GLY	A	4	504 	0ZA	A	B	3
FT	#HET	81	 136 	LYS	A	4	504 	0ZA	A	B	1
FT	#HET	95	 150 	HIS	A	3	503 	ZN	A	S	3
FT	#HET	113	 168 	LYS	A	4	504 	0ZA	A	B	2
FT	#HET	114	 169 	PHE	A	4	504 	0ZA	A	S	3
FT	#HET	121	 176 	TRP	A	4	504 	0ZA	A	S	3
FT	#HET	137	 192 	ASP	A	2	502 	ZN	A	S	3
FT	#HET	236	 291 	GLY	A	4	504 	0ZA	A	B	8
FT	#HET	237	 292 	THR	A	4	504 	0ZA	A	A	5
FT	#HET	238	 293 	THR	A	4	504 	0ZA	A	A	8
FT	#HET	239	 294 	ASN	A	4	504 	0ZA	A	A	6
FT	#HET	241	 296 	ARG	A	4	504 	0ZA	A	S	1
FT	#HET	402	 457 	HIS	A	1	501 	ZN	A	S	4
FT	#HET	403	 458 	HIS	A	2	502 	ZN	A	A	5
FT	#HET	404	 459 	HIS	A	1	501 	ZN	A	S	3
FT	#HET	405	 460 	HIS	A	2	502 	ZN	A	S	3
FT	DISORDER	1	2
FT	DISORDER	163	172
FT	DISORDER	406	406
CC	SEQUENCE	393 AA (ATOM);
CC	GSFVEMVDNL RGKSGQGYYV EMTVGSPPQT LNILVDTGSS NFAVGAAPHP FLHRYYQRQL
CC	SSTYRDLRKG VYVPYTQGKW EGELGTDLVS IPHGPNVTVR ANIAAITESD KFFINGSNWE
CC	GILGLAYAEI ARPDDSLEPF FDSLVKQTHV PNLFSLQLCG LASVGGSMII GGIDHSLYTG
CC	SLWYTPIRRE WYYEVIIVRV EINGQDLKMD CKEYNYDKSI VDSGTTNLRL PKKVFEAAVK
CC	SIKAASSTEK FPDGFWLGEQ LVCWQAGTTP WNIFPVISLY LMGEVTNQSF RITILPQQYL
CC	RPVEDVATSQ DDCYKFAISQ SSTGTVMGAV IMEGFYVVFD RARKRIGFAV SACHVHDEFR
CC	TAAVEGPFVT LDMEDCGYNI PQTDESRSHH HHH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAP
CC	ATOM   --GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAP
CC	         ************************************************
CC	SEQRES HPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVT
CC	ATOM   HPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVT
CC	       **************************************************
CC	SEQRES VRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQT
CC	ATOM   VRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQT
CC	       **************************************************
CC	SEQRES HVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIR
CC	ATOM   HVPNLFSLQLCG----------LASVGGSMIIGGIDHSLYTGSLWYTPIR
CC	       ************          ****************************
CC	SEQRES REWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAA
CC	ATOM   REWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAA
CC	       **************************************************
CC	SEQRES VKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQ
CC	ATOM   VKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQ
CC	       **************************************************
CC	SEQRES SFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVV
CC	ATOM   SFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVV
CC	       **************************************************
CC	SEQRES FDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESRS
CC	ATOM   FDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESRS
CC	       **************************************************
CC	SEQRES HHHHHH
CC	ATOM   HHHHH-
CC	       ***** 
SQ	SEQUENCE	406 AA;      MW;         CN;
	MRGSFVEMVD NLRGKSGQGY YVEMTVGSPP QTLNILVDTG SSNFAVGAAP HPFLHRYYQR
	QLSSTYRDLR KGVYVPYTQG KWEGELGTDL VSIPHGPNVT VRANIAAITE SDKFFINGSN
	WEGILGLAYA EIARPDDSLE PFFDSLVKQT HVPNLFSLQL CGAGFPLNQS EVLASVGGSM
	IIGGIDHSLY TGSLWYTPIR REWYYEVIIV RVEINGQDLK MDCKEYNYDK SIVDSGTTNL
	RLPKKVFEAA VKSIKAASST EKFPDGFWLG EQLVCWQAGT TPWNIFPVIS LYLMGEVTNQ
	SFRITILPQQ YLRPVEDVAT SQDDCYKFAI SQSSTGTVMG AVIMEGFYVV FDRARKRIGF
	AVSACHVHDE FRTAAVEGPF VTLDMEDCGY NIPQTDESRS HHHHHH
//