ID	4HVDA	STANDARD;	PRT;	314	AA.
DT	CONVERTED FROM PDB (SEQRES) 4HVD
DE	Tyrosine-protein kinase JAK3
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.850
CC	R-Factor	0.225
FT	#HET	18	 828 	LEU	A	2	1202 	933	A	A	3
FT	#HET	19	 829 	GLY	A	2	1202 	933	A	B	2
FT	#HET	26	 836 	VAL	A	2	1202 	933	A	S	5
FT	#HET	43	 853 	ALA	A	2	1202 	933	A	S	3
FT	#HET	92	 902 	MET	A	2	1202 	933	A	S	2
FT	#HET	93	 903 	GLU	A	2	1202 	933	A	B	3
FT	#HET	94	 904 	TYR	A	2	1202 	933	A	A	5
FT	#HET	95	 905 	LEU	A	2	1202 	933	A	A	9
FT	#HET	98	 908 	GLY	A	2	1202 	933	A	B	2
FT	#HET	99	 909 	CYS	A	2	1202 	933	A	B	1
FT	#HET	143	 953 	ARG	A	2	1202 	933	A	B	1
FT	#HET	144	 954 	ASN	A	2	1202 	933	A	S	1
FT	#HET	146	 956 	LEU	A	2	1202 	933	A	S	8
FT	#HET	156	 966 	ALA	A	2	1202 	933	A	S	1
FT	#HET	157	 967 	ASP	A	2	1202 	933	A	A	2
FT	#HET	182	 992 	PHE	A	1	1201 	PHU	A	S	1
FT	#HET	201	1011 	TRP	A	1	1201 	PHU	A	S	3
FT	#HET	220	1030 	PRO	A	1	1201 	PHU	A	B	1
FT	#HET	224	1034 	PHE	A	1	1201 	PHU	A	A	4
FT	#HET	227	1037 	MET	A	1	1201 	PHU	A	S	1
FT	#HET	244	1054 	LEU	A	1	1201 	PHU	A	S	4
FT	#HET	249	1059 	ARG	A	1	1201 	PHU	A	A	4
FT	#HET	250	1060 	LEU	A	1	1201 	PHU	A	A	13
FT	#HET	268	1078 	TRP	A	1	1201 	PHU	A	S	5
FT	DISORDER	1	4
FT	DISORDER	82	87
FT	DISORDER	229	233
FT	DISORDER	292	314
CC	SEQUENCE	276 AA (ATOM);
CC	TIFEERHLKY ISQLGKGNFG SVELCRYDPL GDNTGALVAV KQLQHSGPDQ QRDFQREIQI
CC	LKALHSDFIV KYRGVSYLRL VMEYLPSGCL RDFLQRHRAR LDASRLLLYS SQICKGMEYL
CC	GSRRCVHRDL AARNILVESE AHVKIADFGL AKLLPLDKDY YVVREPGQSP IFWYAPESLS
CC	DNIFSRQSDV WSFGVVLYEL FTYCDKSCSP SAEFLRMMVP ALSRLLELLE EGQRLPAPPA
CC	CPAEVHELMK LCWAPSPQDR PSFSALGPQL DMLWSG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES CQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHS
CC	ATOM   ----TIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHS
CC	           **********************************************
CC	SEQRES GPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCL
CC	ATOM   GPDQQRDFQREIQILKALHSDFIVKYRGVSY------LRLVMEYLPSGCL
CC	       *******************************      *************
CC	SEQRES RDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESE
CC	ATOM   RDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESE
CC	       **************************************************
CC	SEQRES AHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDV
CC	ATOM   AHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDV
CC	       **************************************************
CC	SEQRES WSFGVVLYELFTYCDKSCSPSAEFLRMMGSERDVPALSRLLELLEEGQRL
CC	ATOM   WSFGVVLYELFTYCDKSCSPSAEFLRMM-----VPALSRLLELLEEGQRL
CC	       ****************************     *****************
CC	SEQRES PAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAF
CC	ATOM   PAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSG---------
CC	       *****************************************         
CC	SEQRES TAHPEGKHHSLSFS
CC	ATOM   --------------
CC	                     
SQ	SEQUENCE	314 AA;      MW;         CN;
	CQDPTIFEER HLKYISQLGK GNFGSVELCR YDPLGDNTGA LVAVKQLQHS GPDQQRDFQR
	EIQILKALHS DFIVKYRGVS YGPGRQSLRL VMEYLPSGCL RDFLQRHRAR LDASRLLLYS
	SQICKGMEYL GSRRCVHRDL AARNILVESE AHVKIADFGL AKLLPLDKDY YVVREPGQSP
	IFWYAPESLS DNIFSRQSDV WSFGVVLYEL FTYCDKSCSP SAEFLRMMGS ERDVPALSRL
	LELLEEGQRL PAPPACPAEV HELMKLCWAP SPQDRPSFSA LGPQLDMLWS GSRGCETHAF
	TAHPEGKHHS LSFS
//