ID	4GJ3A	STANDARD;	PRT;	302	AA.
DT	CONVERTED FROM PDB (SEQRES) 4GJ3
DE	Non-receptor tyrosine-protein kinase TYK2
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.500
CC	R-Factor	0.212
FT	#HET	20	 901 	ARG	A	1	1201 	0XP	A	S	5
FT	#HET	22	 903 	LEU	A	1	1201 	0XP	A	A	6
FT	#HET	23	 904 	GLY	A	1	1201 	0XP	A	B	3
FT	#HET	24	 905 	GLU	A	1	1201 	0XP	A	B	5
FT	#HET	30	 911 	VAL	A	1	1201 	0XP	A	S	2
FT	#HET	47	 928 	ALA	A	1	1201 	0XP	A	S	1
FT	#HET	98	 979 	GLU	A	1	1201 	0XP	A	B	1
FT	#HET	99	 980 	TYR	A	1	1201 	0XP	A	S	13
FT	#HET	100	 981 	VAL	A	1	1201 	0XP	A	B	11
FT	#HET	101	 982 	PRO	A	1	1201 	0XP	A	B	8
FT	#HET	102	 983 	LEU	A	1	1201 	0XP	A	B	5
FT	#HET	103	 984 	GLY	A	1	1201 	0XP	A	B	9
FT	#HET	146	1027 	ARG	A	1	1201 	0XP	A	A	7
FT	#HET	147	1028 	ASN	A	1	1201 	0XP	A	A	4
FT	#HET	149	1030 	LEU	A	1	1201 	0XP	A	S	5
FT	#HET	159	1040 	GLY	A	1	1201 	0XP	A	B	2
FT	#HET	160	1041 	ASP	A	1	1201 	0XP	A	A	2
FT	DISORDER	1	8
FT	DISORDER	297	302
CC	SEQUENCE	288 AA (ATOM);
CC	TVFHKRYLKK IRDLGEGHFG KVSLYCYDPT NDGTGEMVAV KALKADAGPQ HRSGWKQEID
CC	ILRTLYHEHI IKYKGCCEDA GAASLQLVME YVPLGSLRDY LPRHSIGLAQ LLLFAQQICE
CC	GMAYLHAQHY IHRNLAARNV LLDNDRLVKI GDFGLAKAVP EGHEYYRVRE DGDSPVFWYA
CC	PECLKEYKFY YASDVWSFGV TLYELLTHCD SSQSPPTKFL ELIGIAQGQM TVLRLTELLE
CC	RGERLPRPDK CPAEVYHLMK NCWETEASFR PTFENLIPIL KTVHEKYR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MGSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA
CC	ATOM   --------TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA
CC	               ******************************************
CC	SEQRES LKADAGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDAGAASLQLVMEYV
CC	ATOM   LKADAGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDAGAASLQLVMEYV
CC	       **************************************************
CC	SEQRES PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRNLAARNVLL
CC	ATOM   PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRNLAARNVLL
CC	       **************************************************
CC	SEQRES DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA
CC	ATOM   DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA
CC	       **************************************************
CC	SEQRES SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG
CC	ATOM   SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG
CC	       **************************************************
CC	SEQRES ERLPRPDKCPAEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYRHHHH
CC	ATOM   ERLPRPDKCPAEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYR----
CC	       **********************************************    
CC	SEQRES HH
CC	ATOM   --
CC	         
SQ	SEQUENCE	302 AA;      MW;         CN;
	MGSPASDPTV FHKRYLKKIR DLGEGHFGKV SLYCYDPTND GTGEMVAVKA LKADAGPQHR
	SGWKQEIDIL RTLYHEHIIK YKGCCEDAGA ASLQLVMEYV PLGSLRDYLP RHSIGLAQLL
	LFAQQICEGM AYLHAQHYIH RNLAARNVLL DNDRLVKIGD FGLAKAVPEG HEYYRVREDG
	DSPVFWYAPE CLKEYKFYYA SDVWSFGVTL YELLTHCDSS QSPPTKFLEL IGIAQGQMTV
	LRLTELLERG ERLPRPDKCP AEVYHLMKNC WETEASFRPT FENLIPILKT VHEKYRHHHH
	HH
//