ID	4G2JA	STANDARD;	PRT;	329	AA.
DT	CONVERTED FROM PDB (SEQRES) 4G2J
DE	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.400
CC	R-Factor	0.202
FT	#SUB	131	 308 	ARG	A	172	 349 	PHE	B	Protein	S	12
FT	#SUB	135	 312 	ALA	A	176	 353 	ARG	B	Protein	B	2
FT	#SUB	136	 313 	VAL	A	150	 327 	ALA	B	Protein	A	3
FT	#SUB	136	 313 	VAL	A	154	 331 	GLN	B	Protein	S	1
FT	#SUB	136	 313 	VAL	A	176	 353 	ARG	B	Protein	B	2
FT	#SUB	137	 314 	ARG	A	137	 314 	ARG	B	Protein	S	3
FT	#SUB	137	 314 	ARG	A	138	 315 	TYR	B	Protein	A	5
FT	#SUB	137	 314 	ARG	A	150	 327 	ALA	B	Protein	B	2
FT	#SUB	138	 315 	TYR	A	137	 314 	ARG	B	Protein	S	5
FT	#SUB	138	 315 	TYR	A	138	 315 	TYR	B	Protein	S	4
FT	#SUB	139	 316 	ASN	A	146	 323 	ASN	B	Protein	S	8
FT	#SUB	139	 316 	ASN	A	149	 326 	CYS	B	Protein	S	7
FT	#SUB	139	 316 	ASN	A	150	 327 	ALA	B	Protein	S	2
FT	#SUB	139	 316 	ASN	A	176	 353 	ARG	B	Protein	B	2
FT	#SUB	139	 316 	ASN	A	180	 357 	ILE	B	Protein	A	7
FT	#SUB	140	 317 	ASP	A	176	 353 	ARG	B	Protein	A	11
FT	#SUB	141	 318 	ILE	A	184	 361 	LEU	B	Protein	S	1
FT	#SUB	146	 323 	ASN	A	139	 316 	ASN	B	Protein	A	4
FT	#SUB	149	 326 	CYS	A	139	 316 	ASN	B	Protein	A	5
FT	#SUB	150	 327 	ALA	A	136	 313 	VAL	B	Protein	A	3
FT	#SUB	150	 327 	ALA	A	137	 314 	ARG	B	Protein	S	1
FT	#SUB	150	 327 	ALA	A	139	 316 	ASN	B	Protein	B	2
FT	#SUB	154	 331 	GLN	A	136	 313 	VAL	B	Protein	S	1
FT	#SUB	172	 349 	PHE	A	131	 308 	ARG	B	Protein	S	6
FT	#SUB	176	 353 	ARG	A	135	 312 	ALA	B	Protein	S	2
FT	#SUB	176	 353 	ARG	A	136	 313 	VAL	B	Protein	S	1
FT	#SUB	176	 353 	ARG	A	139	 316 	ASN	B	Protein	S	2
FT	#SUB	176	 353 	ARG	A	140	 317 	ASP	B	Protein	S	11
FT	#SUB	180	 357 	ILE	A	139	 316 	ASN	B	Protein	S	5
FT	#SUB	184	 361 	LEU	A	141	 318 	ILE	B	Protein	S	1
FT	#HET	74	 251 	PHE	A	3	903 	0WF	A	S	2
FT	#HET	75	 252 	HIS	A	3	903 	0WF	A	S	4
FT	#HET	79	 256 	HIS	A	1	901 	ZN	A	S	3
FT	#HET	115	 292 	HIS	A	1	901 	ZN	A	S	3
FT	#HET	116	 293 	ASP	A	1	901 	ZN	A	S	3
FT	#HET	116	 293 	ASP	A	2	902 	MG	A	S	3
FT	#HET	148	 325 	HIS	A	2	902 	MG	A	S	1
FT	#HET	188	 365 	MET	A	3	903 	0WF	A	S	7
FT	#HET	225	 402 	ASP	A	1	901 	ZN	A	S	3
FT	#HET	226	 403 	ILE	A	3	903 	0WF	A	A	7
FT	#HET	228	 405 	ASN	A	3	903 	0WF	A	S	1
FT	#HET	240	 417 	VAL	A	3	903 	0WF	A	S	1
FT	#HET	243	 420 	LEU	A	3	903 	0WF	A	S	13
FT	#HET	244	 421 	LEU	A	3	903 	0WF	A	S	1
FT	#HET	247	 424 	TYR	A	3	903 	0WF	A	S	19
FT	#HET	264	 441 	PHE	A	3	903 	0WF	A	A	15
FT	#HET	275	 452 	ALA	A	3	903 	0WF	A	A	12
FT	#HET	276	 453 	GLN	A	3	903 	0WF	A	S	18
FT	#HET	278	 455 	GLY	A	3	903 	0WF	A	B	8
FT	#HET	279	 456 	PHE	A	3	903 	0WF	A	A	33
FT	#HET	283	 460 	VAL	A	3	903 	0WF	A	S	4
FT	DISORDER	329	329
CC	SEQUENCE	328 AA (ATOM);
CC	GSHMTYPKYL LSPETIEALR KPTFDVWLWE PNEMLSCLEH MYHDLGLVRD FSINPVTLRR
CC	WLFCVHDNYR NNPFHNFRHC FCVAQMMYSM VWLCSLQEKF SQTDILILMT AAICHDLDHP
CC	GYNNTYQINA RTELAVRYND ISPLENHHCA VAFQILAEPE CNIFSNIPPD GFKQIRQGMI
CC	TLILATDMAR HAEIMDSFKE KMENFDYSNE EHMTLLKMIL IKCCDISNEV RPMEVAEPWV
CC	DCLLEEYFMQ SDREKSEGLP VAPFMDRDKV TKATAQIGFI KFVLIPMFET VTKLFPMVEE
CC	IMLQPLWESR DRYEELKRID DAMKELQK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSHMTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRD
CC	ATOM   GSHMTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRD
CC	       **************************************************
CC	SEQRES FSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF
CC	ATOM   FSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF
CC	       **************************************************
CC	SEQRES SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
CC	ATOM   SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
CC	       **************************************************
CC	SEQRES VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKE
CC	ATOM   VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKE
CC	       **************************************************
CC	SEQRES KMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQ
CC	ATOM   KMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQ
CC	       **************************************************
CC	SEQRES SDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEE
CC	ATOM   SDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEE
CC	       **************************************************
CC	SEQRES IMLQPLWESRDRYEELKRIDDAMKELQKK
CC	ATOM   IMLQPLWESRDRYEELKRIDDAMKELQK-
CC	       **************************** 
SQ	SEQUENCE	329 AA;      MW;         CN;
	GSHMTYPKYL LSPETIEALR KPTFDVWLWE PNEMLSCLEH MYHDLGLVRD FSINPVTLRR
	WLFCVHDNYR NNPFHNFRHC FCVAQMMYSM VWLCSLQEKF SQTDILILMT AAICHDLDHP
	GYNNTYQINA RTELAVRYND ISPLENHHCA VAFQILAEPE CNIFSNIPPD GFKQIRQGMI
	TLILATDMAR HAEIMDSFKE KMENFDYSNE EHMTLLKMIL IKCCDISNEV RPMEVAEPWV
	DCLLEEYFMQ SDREKSEGLP VAPFMDRDKV TKATAQIGFI KFVLIPMFET VTKLFPMVEE
	IMLQPLWESR DRYEELKRID DAMKELQKK
//
ID	4G2JB	STANDARD;	PRT;	329	AA.
DT	CONVERTED FROM PDB (SEQRES) 4G2J
DE	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.400
CC	R-Factor	0.202
FT	#SUB	131	 308 	ARG	B	172	 349 	PHE	A	Protein	S	6
FT	#SUB	135	 312 	ALA	B	176	 353 	ARG	A	Protein	B	2
FT	#SUB	136	 313 	VAL	B	150	 327 	ALA	A	Protein	A	3
FT	#SUB	136	 313 	VAL	B	154	 331 	GLN	A	Protein	S	1
FT	#SUB	136	 313 	VAL	B	176	 353 	ARG	A	Protein	B	1
FT	#SUB	137	 314 	ARG	B	137	 314 	ARG	A	Protein	S	3
FT	#SUB	137	 314 	ARG	B	138	 315 	TYR	A	Protein	A	5
FT	#SUB	137	 314 	ARG	B	150	 327 	ALA	A	Protein	B	1
FT	#SUB	138	 315 	TYR	B	137	 314 	ARG	A	Protein	S	5
FT	#SUB	138	 315 	TYR	B	138	 315 	TYR	A	Protein	S	4
FT	#SUB	139	 316 	ASN	B	146	 323 	ASN	A	Protein	S	4
FT	#SUB	139	 316 	ASN	B	149	 326 	CYS	A	Protein	S	5
FT	#SUB	139	 316 	ASN	B	150	 327 	ALA	A	Protein	S	2
FT	#SUB	139	 316 	ASN	B	176	 353 	ARG	A	Protein	B	2
FT	#SUB	139	 316 	ASN	B	180	 357 	ILE	A	Protein	A	5
FT	#SUB	140	 317 	ASP	B	176	 353 	ARG	A	Protein	A	11
FT	#SUB	141	 318 	ILE	B	184	 361 	LEU	A	Protein	S	1
FT	#SUB	146	 323 	ASN	B	139	 316 	ASN	A	Protein	A	8
FT	#SUB	149	 326 	CYS	B	139	 316 	ASN	A	Protein	A	7
FT	#SUB	150	 327 	ALA	B	136	 313 	VAL	A	Protein	A	3
FT	#SUB	150	 327 	ALA	B	137	 314 	ARG	A	Protein	S	2
FT	#SUB	150	 327 	ALA	B	139	 316 	ASN	A	Protein	B	2
FT	#SUB	154	 331 	GLN	B	136	 313 	VAL	A	Protein	S	1
FT	#SUB	172	 349 	PHE	B	131	 308 	ARG	A	Protein	S	12
FT	#SUB	176	 353 	ARG	B	135	 312 	ALA	A	Protein	S	2
FT	#SUB	176	 353 	ARG	B	136	 313 	VAL	A	Protein	S	2
FT	#SUB	176	 353 	ARG	B	139	 316 	ASN	A	Protein	S	2
FT	#SUB	176	 353 	ARG	B	140	 317 	ASP	A	Protein	S	11
FT	#SUB	180	 357 	ILE	B	139	 316 	ASN	A	Protein	S	7
FT	#SUB	184	 361 	LEU	B	141	 318 	ILE	A	Protein	S	1
FT	#HET	74	 251 	PHE	B	6	903 	0WF	B	S	1
FT	#HET	75	 252 	HIS	B	6	903 	0WF	B	S	6
FT	#HET	79	 256 	HIS	B	4	901 	ZN	B	S	3
FT	#HET	115	 292 	HIS	B	4	901 	ZN	B	S	3
FT	#HET	116	 293 	ASP	B	4	901 	ZN	B	S	3
FT	#HET	116	 293 	ASP	B	5	902 	MG	B	S	3
FT	#HET	148	 325 	HIS	B	5	902 	MG	B	S	1
FT	#HET	188	 365 	MET	B	6	903 	0WF	B	S	8
FT	#HET	225	 402 	ASP	B	4	901 	ZN	B	S	3
FT	#HET	226	 403 	ILE	B	6	903 	0WF	B	A	10
FT	#HET	243	 420 	LEU	B	6	903 	0WF	B	S	13
FT	#HET	247	 424 	TYR	B	6	903 	0WF	B	S	20
FT	#HET	264	 441 	PHE	B	6	903 	0WF	B	S	12
FT	#HET	275	 452 	ALA	B	6	903 	0WF	B	A	14
FT	#HET	276	 453 	GLN	B	6	903 	0WF	B	S	15
FT	#HET	279	 456 	PHE	B	6	903 	0WF	B	S	30
FT	#HET	283	 460 	VAL	B	6	903 	0WF	B	S	1
FT	DISORDER	329	329
CC	SEQUENCE	328 AA (ATOM);
CC	GSHMTYPKYL LSPETIEALR KPTFDVWLWE PNEMLSCLEH MYHDLGLVRD FSINPVTLRR
CC	WLFCVHDNYR NNPFHNFRHC FCVAQMMYSM VWLCSLQEKF SQTDILILMT AAICHDLDHP
CC	GYNNTYQINA RTELAVRYND ISPLENHHCA VAFQILAEPE CNIFSNIPPD GFKQIRQGMI
CC	TLILATDMAR HAEIMDSFKE KMENFDYSNE EHMTLLKMIL IKCCDISNEV RPMEVAEPWV
CC	DCLLEEYFMQ SDREKSEGLP VAPFMDRDKV TKATAQIGFI KFVLIPMFET VTKLFPMVEE
CC	IMLQPLWESR DRYEELKRID DAMKELQK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSHMTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRD
CC	ATOM   GSHMTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRD
CC	       **************************************************
CC	SEQRES FSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF
CC	ATOM   FSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKF
CC	       **************************************************
CC	SEQRES SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
CC	ATOM   SQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
CC	       **************************************************
CC	SEQRES VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKE
CC	ATOM   VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKE
CC	       **************************************************
CC	SEQRES KMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQ
CC	ATOM   KMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQ
CC	       **************************************************
CC	SEQRES SDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEE
CC	ATOM   SDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEE
CC	       **************************************************
CC	SEQRES IMLQPLWESRDRYEELKRIDDAMKELQKK
CC	ATOM   IMLQPLWESRDRYEELKRIDDAMKELQK-
CC	       **************************** 
SQ	SEQUENCE	329 AA;      MW;         CN;
	GSHMTYPKYL LSPETIEALR KPTFDVWLWE PNEMLSCLEH MYHDLGLVRD FSINPVTLRR
	WLFCVHDNYR NNPFHNFRHC FCVAQMMYSM VWLCSLQEKF SQTDILILMT AAICHDLDHP
	GYNNTYQINA RTELAVRYND ISPLENHHCA VAFQILAEPE CNIFSNIPPD GFKQIRQGMI
	TLILATDMAR HAEIMDSFKE KMENFDYSNE EHMTLLKMIL IKCCDISNEV RPMEVAEPWV
	DCLLEEYFMQ SDREKSEGLP VAPFMDRDKV TKATAQIGFI KFVLIPMFET VTKLFPMVEE
	IMLQPLWESR DRYEELKRID DAMKELQKK
//