ID	4FZ7A	STANDARD;	PRT;	291	AA.
DT	CONVERTED FROM PDB (SEQRES) 4FZ7
DE	Tyrosine-protein kinase SYK
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.750
CC	R-Factor	0.202
FT	#HET	25	 377 	LEU	A	1	701 	0VH	A	A	4
FT	#HET	26	 378 	GLY	A	1	701 	0VH	A	B	2
FT	#HET	30	 382 	PHE	A	1	701 	0VH	A	S	1
FT	#HET	48	 400 	ALA	A	1	701 	0VH	A	S	4
FT	#HET	50	 402 	LYS	A	1	701 	0VH	A	S	1
FT	#HET	81	 433 	VAL	A	1	701 	0VH	A	S	1
FT	#HET	96	 448 	MET	A	1	701 	0VH	A	S	5
FT	#HET	97	 449 	GLU	A	1	701 	0VH	A	B	3
FT	#HET	98	 450 	MET	A	1	701 	0VH	A	A	4
FT	#HET	99	 451 	ALA	A	1	701 	0VH	A	A	6
FT	#HET	102	 454 	GLY	A	1	701 	0VH	A	B	3
FT	#HET	103	 455 	PRO	A	1	701 	0VH	A	S	4
FT	#HET	106	 458 	LYS	A	1	701 	0VH	A	S	2
FT	#HET	146	 498 	ARG	A	1	701 	0VH	A	B	4
FT	#HET	147	 499 	ASN	A	1	701 	0VH	A	S	1
FT	#HET	149	 501 	LEU	A	1	701 	0VH	A	S	5
FT	#HET	159	 511 	SER	A	1	701 	0VH	A	S	3
FT	#HET	160	 512 	ASP	A	1	701 	0VH	A	S	13
FT	DISORDER	1	10
FT	DISORDER	28	29
FT	DISORDER	53	58
FT	DISORDER	177	180
FT	DISORDER	288	291
CC	SEQUENCE	265 AA (ATOM);
CC	VYLDRKLLTL EDKELGSFGT VKKGYYQMKK VVKTVAVKIL PALKDELLAE ANVMQQLDNP
CC	YIVRMIGICE AESWMLVMEM AELGPLNKYL QQNRHVKDKN IIELVHQVSM GMKYLEESNF
CC	VHRDLAARNV LLVTQHYAKI SDFGLSKALR ADENYYKAKW PVKWYAPECI NYYKFSSKSD
CC	VWSFGVLMWE AFSYGQKPYR GMKGSEVTAM LEKGERMGCP AGCPREMYDL MNLCWTYDVE
CC	NRPGFAAVEL RLRNYYYDVV NEGHH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MALEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVK
CC	ATOM   ----------VYLDRKLLTLEDKELGS--FGTVKKGYYQMKKVVKTVAVK
CC	                 *****************  *********************
CC	SEQRES ILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAE
CC	ATOM   IL------PALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAE
CC	       **      ******************************************
CC	SEQRES LGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLL
CC	ATOM   LGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLL
CC	       **************************************************
CC	SEQRES VTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSK
CC	ATOM   VTQHYAKISDFGLSKALRADENYYKA----KWPVKWYAPECINYYKFSSK
CC	       **************************    ********************
CC	SEQRES SDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMY
CC	ATOM   SDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMY
CC	       **************************************************
CC	SEQRES DLMNLCWTYDVENRPGFAAVELRLRNYYYDVVNEGHHHHHH
CC	ATOM   DLMNLCWTYDVENRPGFAAVELRLRNYYYDVVNEGHH----
CC	       *************************************    
SQ	SEQUENCE	291 AA;      MW;         CN;
	MALEEIRPKE VYLDRKLLTL EDKELGSGNF GTVKKGYYQM KKVVKTVAVK ILKNEANDPA
	LKDELLAEAN VMQQLDNPYI VRMIGICEAE SWMLVMEMAE LGPLNKYLQQ NRHVKDKNII
	ELVHQVSMGM KYLEESNFVH RDLAARNVLL VTQHYAKISD FGLSKALRAD ENYYKAQTHG
	KWPVKWYAPE CINYYKFSSK SDVWSFGVLM WEAFSYGQKP YRGMKGSEVT AMLEKGERMG
	CPAGCPREMY DLMNLCWTYD VENRPGFAAV ELRLRNYYYD VVNEGHHHHH H
//