ID	4FZ6A	STANDARD;	PRT;	291	AA.
DT	CONVERTED FROM PDB (SEQRES) 4FZ6
DE	Tyrosine-protein kinase SYK
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.850
CC	R-Factor	0.230
FT	#HET	25	 377 	LEU	A	1	701 	0VG	A	B	1
FT	#HET	30	 382 	PHE	A	1	701 	0VG	A	S	1
FT	#HET	33	 385 	VAL	A	1	701 	0VG	A	S	6
FT	#HET	48	 400 	ALA	A	1	701 	0VG	A	S	6
FT	#HET	96	 448 	MET	A	1	701 	0VG	A	S	4
FT	#HET	97	 449 	GLU	A	1	701 	0VG	A	B	3
FT	#HET	98	 450 	MET	A	1	701 	0VG	A	A	6
FT	#HET	99	 451 	ALA	A	1	701 	0VG	A	A	8
FT	#HET	100	 452 	GLU	A	1	701 	0VG	A	B	3
FT	#HET	102	 454 	GLY	A	1	701 	0VG	A	B	6
FT	#HET	103	 455 	PRO	A	1	701 	0VG	A	S	2
FT	#HET	149	 501 	LEU	A	1	701 	0VG	A	S	7
FT	DISORDER	1	10
FT	DISORDER	28	29
FT	DISORDER	54	58
FT	DISORDER	177	180
FT	DISORDER	288	291
CC	SEQUENCE	266 AA (ATOM);
CC	VYLDRKLLTL EDKELGSFGT VKKGYYQMKK VVKTVAVKIL KPALKDELLA EANVMQQLDN
CC	PYIVRMIGIC EAESWMLVME MAELGPLNKY LQQNRHVKDK NIIELVHQVS MGMKYLEESN
CC	FVHRDLAARN VLLVTQHYAK ISDFGLSKAL RADENYYKAK WPVKWYAPEC INYYKFSSKS
CC	DVWSFGVLMW EAFSYGQKPY RGMKGSEVTA MLEKGERMGC PAGCPREMYD LMNLCWTYDV
CC	ENRPGFAAVE LRLRNYYYDV VNEGHH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MALEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVK
CC	ATOM   ----------VYLDRKLLTLEDKELGS--FGTVKKGYYQMKKVVKTVAVK
CC	                 *****************  *********************
CC	SEQRES ILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAE
CC	ATOM   ILK-----PALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAE
CC	       ***     ******************************************
CC	SEQRES LGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLL
CC	ATOM   LGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLL
CC	       **************************************************
CC	SEQRES VTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSK
CC	ATOM   VTQHYAKISDFGLSKALRADENYYKA----KWPVKWYAPECINYYKFSSK
CC	       **************************    ********************
CC	SEQRES SDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMY
CC	ATOM   SDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMY
CC	       **************************************************
CC	SEQRES DLMNLCWTYDVENRPGFAAVELRLRNYYYDVVNEGHHHHHH
CC	ATOM   DLMNLCWTYDVENRPGFAAVELRLRNYYYDVVNEGHH----
CC	       *************************************    
SQ	SEQUENCE	291 AA;      MW;         CN;
	MALEEIRPKE VYLDRKLLTL EDKELGSGNF GTVKKGYYQM KKVVKTVAVK ILKNEANDPA
	LKDELLAEAN VMQQLDNPYI VRMIGICEAE SWMLVMEMAE LGPLNKYLQQ NRHVKDKNII
	ELVHQVSMGM KYLEESNFVH RDLAARNVLL VTQHYAKISD FGLSKALRAD ENYYKAQTHG
	KWPVKWYAPE CINYYKFSSK SDVWSFGVLM WEAFSYGQKP YRGMKGSEVT AMLEKGERMG
	CPAGCPREMY DLMNLCWTYD VENRPGFAAV ELRLRNYYYD VVNEGHHHHH H
//