ID	4FULA	STANDARD;	PRT;	966	AA.
DT	CONVERTED FROM PDB (SEQRES) 4FUL
DE	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isof
DE	orm
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.470
CC	R-Factor	0.210
FT	#HET	662	 804 	MET	A	1	1201 	0VU	A	S	4
FT	#HET	664	 806 	SER	A	1	1201 	0VU	A	S	1
FT	#HET	668	 810 	PRO	A	1	1201 	0VU	A	S	1
FT	#HET	670	 812 	TRP	A	1	1201 	0VU	A	S	8
FT	#HET	689	 831 	ILE	A	1	1201 	0VU	A	S	1
FT	#HET	691	 833 	LYS	A	1	1201 	0VU	A	S	4
FT	#HET	725	 867 	TYR	A	1	1201 	0VU	A	S	6
FT	#HET	737	 879 	ILE	A	1	1201 	0VU	A	S	5
FT	#HET	738	 880 	GLU	A	1	1201 	0VU	A	B	3
FT	#HET	739	 881 	ILE	A	1	1201 	0VU	A	A	3
FT	#HET	740	 882 	VAL	A	1	1201 	0VU	A	A	15
FT	#HET	743	 885 	ALA	A	1	1201 	0VU	A	B	5
FT	#HET	745	 887 	THR	A	1	1201 	0VU	A	S	1
FT	#HET	748	 890 	LYS	A	1	1201 	0VU	A	S	3
FT	#HET	811	 953 	MET	A	1	1201 	0VU	A	S	5
FT	#HET	819	 961 	PHE	A	1	1201 	0VU	A	S	1
FT	#HET	821	 963 	ILE	A	1	1201 	0VU	A	S	8
FT	#HET	822	 964 	ASP	A	1	1201 	0VU	A	B	1
FT	DISORDER	1	2
FT	DISORDER	111	126
FT	DISORDER	180	214
FT	DISORDER	232	236
FT	DISORDER	294	314
FT	DISORDER	347	354
FT	DISORDER	385	400
FT	DISORDER	827	839
FT	DISORDER	857	858
FT	DISORDER	951	966
CC	SEQUENCE	832 AA (ATOM);
CC	EESQAFQRQL TALIGYDVTD VSNVHDDELE FTRRGLVTPR MAEVASRDPK LYAMHPWVTS
CC	KPLPEYLWKK IANNCIFIVI HRSTTSQTIK VSPDDTPGAI LQSFFTKMDF VLRVCGRDEY
CC	LVGETPIKNF QWVRHCLKNG EEIHVVLDTP PDPALDEVRK ECDRKFRVKI RGIDIPVLLT
CC	VFVEANIQHG QQVLCQRRTS PKPFTEEVLW NVWLEFSIKI KDLPKGALLN LQIYCKVRLL
CC	YYVNLLLIDH RFLLRRGEYV LHMWQISFNA DKLTSATNPD KENSMSISIL LDNYCHPVRA
CC	EMPNQLRKQL EAIIATDPLN PLTAEDKELL WHFRYESLKH PKAYPKLFSS VKWGQQEIVA
CC	KTYQLLARRE VWDQSALDVG LTMQLLDCNF SDENVRAIAV QKLESLEDDD VLHYLLQLVQ
CC	AVKFEPYHDS ALARFLLKRG LRNKRIGHFL FWFLRSEIAQ SRHYQQRFAV ILEAYLRGCG
CC	TAMLHDFTQQ VQVIEMLQKV TLDIKSLSAE KYDVSSQVIS QLKQKLENLQ NSQLPESFRV
CC	PYDPGLKAGA LAIEKCKVMA SKKKPLWLEF KCADPTALSN ETIGIIFKHG DDLRQDMLIL
CC	QILRIMESIW ETESLDLCLL PYGCISTGDK IGMIEIVKDA TTIAKIQQST VGNTGAFKDE
CC	VLNHWLKEKS PTEEKFQAAV ERFVYSCAGY CVATFVLGIG DRHNDNIMIT ETGNLFHIDF
CC	GHIRVPFVLT PDFLFVMGTS KTSPHFQKFQ DICVKAYLAL RHHTNLLIIL FSMMLMTGMP
CC	QLTSKEDIEY IRDALTVGKN EEDAKKYFLD QIEVCRDKGW TVQFNWFLHL VL
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRD
CC	ATOM   --EESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRD
CC	         ************************************************
CC	SEQRES PKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPG
CC	ATOM   PKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPG
CC	       **************************************************
CC	SEQRES AILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQW
CC	ATOM   AILQSFFTKM----------------DFVLRVCGRDEYLVGETPIKNFQW
CC	       **********                ************************
CC	SEQRES VRHCLKNGEEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIH
CC	ATOM   VRHCLKNGEEIHVVLDTPPDPALDEVRKE---------------------
CC	       *****************************                     
CC	SEQRES GKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQ
CC	ATOM   --------------CDRKFRVKIRGIDIPVL-----LTVFVEANIQHGQQ
CC	                     *****************     **************
CC	SEQRES VLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALS
CC	ATOM   VLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYC-------
CC	       *******************************************       
CC	SEQRES SKASAESPSSESKGKVRLLYYVNLLLIDHRFLLRRGEYVLHMWQISGKGE
CC	ATOM   --------------KVRLLYYVNLLLIDHRFLLRRGEYVLHMWQIS----
CC	                     ********************************    
CC	SEQRES DQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEGDR
CC	ATOM   ----FNADKLTSATNPDKENSMSISILLDNYCHP----------------
CC	           ******************************                
CC	SEQRES VRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKL
CC	ATOM   VRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKL
CC	       **************************************************
CC	SEQRES FSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRA
CC	ATOM   FSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRA
CC	       **************************************************
CC	SEQRES IAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIG
CC	ATOM   IAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIG
CC	       **************************************************
CC	SEQRES HFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEML
CC	ATOM   HFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEML
CC	       **************************************************
CC	SEQRES QKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLK
CC	ATOM   QKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLK
CC	       **************************************************
CC	SEQRES AGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDM
CC	ATOM   AGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDM
CC	       **************************************************
CC	SEQRES LILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQ
CC	ATOM   LILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQ
CC	       **************************************************
CC	SEQRES QSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVL
CC	ATOM   QSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVL
CC	       **************************************************
CC	SEQRES GIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFL
CC	ATOM   GIGDRHNDNIMITETGNLFHIDFGHI-------------RVPFVLTPDFL
CC	       **************************             ***********
CC	SEQRES FVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQL
CC	ATOM   FVMGTS--KTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQL
CC	       ******  ******************************************
CC	SEQRES TSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVL
CC	ATOM   TSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVL
CC	       **************************************************
CC	SEQRES GIKQGEKHSAHHHHHH
CC	ATOM   ----------------
CC	                       
SQ	SEQUENCE	966 AA;      MW;         CN;
	MSEESQAFQR QLTALIGYDV TDVSNVHDDE LEFTRRGLVT PRMAEVASRD PKLYAMHPWV
	TSKPLPEYLW KKIANNCIFI VIHRSTTSQT IKVSPDDTPG AILQSFFTKM AKKKSLMDIP
	ESQSEQDFVL RVCGRDEYLV GETPIKNFQW VRHCLKNGEE IHVVLDTPPD PALDEVRKEE
	WPLVDDCTGV TGYHEQLTIH GKDHESVFTV SLWDCDRKFR VKIRGIDIPV LPRNTDLTVF
	VEANIQHGQQ VLCQRRTSPK PFTEEVLWNV WLEFSIKIKD LPKGALLNLQ IYCGKAPALS
	SKASAESPSS ESKGKVRLLY YVNLLLIDHR FLLRRGEYVL HMWQISGKGE DQGSFNADKL
	TSATNPDKEN SMSISILLDN YCHPIALPKH QPTPDPEGDR VRAEMPNQLR KQLEAIIATD
	PLNPLTAEDK ELLWHFRYES LKHPKAYPKL FSSVKWGQQE IVAKTYQLLA RREVWDQSAL
	DVGLTMQLLD CNFSDENVRA IAVQKLESLE DDDVLHYLLQ LVQAVKFEPY HDSALARFLL
	KRGLRNKRIG HFLFWFLRSE IAQSRHYQQR FAVILEAYLR GCGTAMLHDF TQQVQVIEML
	QKVTLDIKSL SAEKYDVSSQ VISQLKQKLE NLQNSQLPES FRVPYDPGLK AGALAIEKCK
	VMASKKKPLW LEFKCADPTA LSNETIGIIF KHGDDLRQDM LILQILRIME SIWETESLDL
	CLLPYGCIST GDKIGMIEIV KDATTIAKIQ QSTVGNTGAF KDEVLNHWLK EKSPTEEKFQ
	AAVERFVYSC AGYCVATFVL GIGDRHNDNI MITETGNLFH IDFGHILGNY KSFLGINKER
	VPFVLTPDFL FVMGTSGKKT SPHFQKFQDI CVKAYLALRH HTNLLIILFS MMLMTGMPQL
	TSKEDIEYIR DALTVGKNEE DAKKYFLDQI EVCRDKGWTV QFNWFLHLVL GIKQGEKHSA
	HHHHHH
//