ID	4FMUA	STANDARD;	PRT;	278	AA.
DT	CONVERTED FROM PDB (SEQRES) 4FMU
DE	Histone-lysine N-methyltransferase SETD2
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.100
CC	R-Factor	0.195
FT	#HET	44	1477 	GLU	A	14	1814 	UNX	A	S	1
FT	#HET	66	1499 	CYS	A	1	1801 	ZN	A	S	2
FT	#HET	68	1501 	CYS	A	1	1801 	ZN	A	S	2
FT	#HET	83	1516 	CYS	A	1	1801 	ZN	A	A	3
FT	#HET	83	1516 	CYS	A	2	1802 	ZN	A	S	2
FT	#HET	87	1520 	CYS	A	1	1801 	ZN	A	S	2
FT	#HET	96	1529 	CYS	A	2	1802 	ZN	A	S	2
FT	#HET	100	1533 	CYS	A	2	1802 	ZN	A	S	2
FT	#HET	106	1539 	CYS	A	2	1802 	ZN	A	S	2
FT	#HET	113	1546 	ARG	A	9	1809 	UNX	A	B	1
FT	#HET	113	1546 	ARG	A	10	1810 	UNX	A	S	1
FT	#HET	114	1547 	LYS	A	9	1809 	UNX	A	B	1
FT	#HET	114	1547 	LYS	A	14	1814 	UNX	A	S	2
FT	#HET	115	1548 	GLN	A	9	1809 	UNX	A	S	1
FT	#HET	127	1560 	LYS	A	4	1804 	0UM	A	A	16
FT	#HET	128	1561 	GLY	A	4	1804 	0UM	A	B	4
FT	#HET	129	1562 	TRP	A	4	1804 	0UM	A	A	11
FT	#HET	146	1579 	TYR	A	4	1804 	0UM	A	S	6
FT	#HET	163	1596 	TYR	A	5	1805 	UNX	A	S	1
FT	#HET	169	1602 	ILE	A	4	1804 	0UM	A	B	1
FT	#HET	170	1603 	HIS	A	4	1804 	0UM	A	A	24
FT	#HET	171	1604 	TYR	A	4	1804 	0UM	A	A	8
FT	#HET	171	1604 	TYR	A	5	1805 	UNX	A	S	2
FT	#HET	172	1605 	TYR	A	4	1804 	0UM	A	S	7
FT	#HET	174	1607 	MET	A	15	1815 	UNX	A	S	1
FT	#HET	174	1607 	MET	A	17	1817 	UNX	A	B	2
FT	#HET	175	1608 	ALA	A	17	1817 	UNX	A	A	3
FT	#HET	177	1610 	LYS	A	11	1811 	UNX	A	A	3
FT	#HET	177	1610 	LYS	A	13	1813 	UNX	A	S	1
FT	#HET	178	1611 	ASN	A	11	1811 	UNX	A	A	3
FT	#HET	179	1612 	ASP	A	6	1806 	UNX	A	B	1
FT	#HET	180	1613 	GLU	A	6	1806 	UNX	A	S	1
FT	#HET	192	1625 	ARG	A	4	1804 	0UM	A	B	7
FT	#HET	193	1626 	PHE	A	4	1804 	0UM	A	A	8
FT	#HET	194	1627 	MET	A	4	1804 	0UM	A	B	2
FT	#HET	195	1628 	ASN	A	4	1804 	0UM	A	A	16
FT	#HET	196	1629 	HIS	A	4	1804 	0UM	A	A	8
FT	#HET	198	1631 	CYS	A	3	1803 	ZN	A	A	3
FT	#HET	203	1636 	GLU	A	7	1807 	UNX	A	A	3
FT	#HET	204	1637 	THR	A	7	1807 	UNX	A	A	2
FT	#HET	204	1637 	THR	A	8	1808 	UNX	A	S	1
FT	#HET	210	1643 	ASN	A	12	1812 	UNX	A	S	1
FT	#HET	231	1664 	PHE	A	4	1804 	0UM	A	S	2
FT	#HET	231	1664 	PHE	A	15	1815 	UNX	A	S	1
FT	#HET	232	1665 	ASP	A	8	1808 	UNX	A	B	1
FT	#HET	233	1666 	TYR	A	4	1804 	0UM	A	S	3
FT	#HET	233	1666 	TYR	A	15	1815 	UNX	A	S	1
FT	#HET	234	1667 	GLN	A	15	1815 	UNX	A	A	5
FT	#HET	234	1667 	GLN	A	17	1817 	UNX	A	B	1
FT	#HET	235	1668 	PHE	A	16	1816 	UNX	A	A	2
FT	#HET	236	1669 	GLN	A	16	1816 	UNX	A	B	1
FT	#HET	243	1676 	GLN	A	4	1804 	0UM	A	S	5
FT	#HET	244	1677 	LYS	A	4	1804 	0UM	A	B	2
FT	#HET	245	1678 	CYS	A	3	1803 	ZN	A	S	2
FT	#HET	245	1678 	CYS	A	4	1804 	0UM	A	A	3
FT	#HET	246	1679 	PHE	A	4	1804 	0UM	A	A	8
FT	#HET	247	1680 	CYS	A	3	1803 	ZN	A	S	2
FT	#HET	247	1680 	CYS	A	4	1804 	0UM	A	B	1
FT	#HET	252	1685 	CYS	A	3	1803 	ZN	A	A	3
FT	#HET	256	1689 	LEU	A	4	1804 	0UM	A	S	7
FT	DISORDER	1	10
FT	DISORDER	51	63
FT	DISORDER	259	278
CC	SEQUENCE	235 AA (ATOM);
CC	LVGPSCVMDD FRDPQRWKEC AKQGKMPCYF DLIEENVYLT MQCECTPLSK DERAQGEIAC
CC	GEDCLNRLLM IECSSRCPNG DYCSNRRFQR KQHADVEVIL TEKKGWGLRA AKDLPSNTFV
CC	LEYCGEVLDH KEFKARVKEY ARNKNIHYYF MALKNDEIID ATQKGNCSRF MNHSCEPNCE
CC	TQKWTVNGQL RVGFFTTKLV PSGSELTFDY QFQRYGKEAQ KCFCGSANCR GYLGG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLT
CC	ATOM   ----------LVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLT
CC	                 ****************************************
CC	SEQRES ERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRC
CC	ATOM   -------------MQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRC
CC	                    *************************************
CC	SEQRES PNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEV
CC	ATOM   PNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEV
CC	       **************************************************
CC	SEQRES LDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEP
CC	ATOM   LDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEP
CC	       **************************************************
CC	SEQRES NCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSA
CC	ATOM   NCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSA
CC	       **************************************************
CC	SEQRES NCRGYLGGENRVSIRAAGGKMKKERSRK
CC	ATOM   NCRGYLGG--------------------
CC	       ********                    
SQ	SEQUENCE	278 AA;      MW;         CN;
	GETSVPPGSA LVGPSCVMDD FRDPQRWKEC AKQGKMPCYF DLIEENVYLT ERKKNKSHRD
	IKRMQCECTP LSKDERAQGE IACGEDCLNR LLMIECSSRC PNGDYCSNRR FQRKQHADVE
	VILTEKKGWG LRAAKDLPSN TFVLEYCGEV LDHKEFKARV KEYARNKNIH YYFMALKNDE
	IIDATQKGNC SRFMNHSCEP NCETQKWTVN GQLRVGFFTT KLVPSGSELT FDYQFQRYGK
	EAQKCFCGSA NCRGYLGGEN RVSIRAAGGK MKKERSRK
//