ID	4FM8A	STANDARD;	PRT;	404	AA.
DT	CONVERTED FROM PDB (SEQRES) 4FM8
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.900
CC	R-Factor	0.201
FT	#HET	15	  11 	GLY	A	1	501 	0UQ	A	B	1
FT	#HET	16	  12 	GLN	A	1	501 	0UQ	A	B	2
FT	#HET	17	  13 	GLY	A	1	501 	0UQ	A	B	2
FT	#HET	34	  30 	LEU	A	1	501 	0UQ	A	S	4
FT	#HET	36	  32 	ASP	A	1	501 	0UQ	A	S	4
FT	#HET	46	  42 	ALA	A	3	503 	EDO	A	B	1
FT	#HET	47	  43 	ALA	A	3	503 	EDO	A	A	5
FT	#HET	49	  45 	HIS	A	3	503 	EDO	A	S	4
FT	#HET	52	  48 	LEU	A	3	503 	EDO	A	S	1
FT	#HET	75	  71 	TYR	A	1	501 	0UQ	A	S	9
FT	#HET	76	  72 	THR	A	1	501 	0UQ	A	A	3
FT	#HET	77	  73 	GLN	A	1	501 	0UQ	A	A	6
FT	#HET	78	  74 	GLY	A	1	501 	0UQ	A	B	6
FT	#HET	79	  75 	LYS	A	1	501 	0UQ	A	B	1
FT	#HET	106	 102 	ILE	A	3	503 	EDO	A	A	4
FT	#HET	108	 104 	GLU	A	3	503 	EDO	A	B	3
FT	#HET	109	 105 	SER	A	3	503 	EDO	A	A	5
FT	#HET	111	 107 	LYS	A	1	501 	0UQ	A	B	1
FT	#HET	112	 108 	PHE	A	1	501 	0UQ	A	A	6
FT	#HET	113	 109 	PHE	A	3	503 	EDO	A	S	3
FT	#HET	114	 110 	ILE	A	1	501 	0UQ	A	S	2
FT	#HET	119	 115 	TRP	A	1	501 	0UQ	A	S	3
FT	#HET	122	 118 	ILE	A	1	501 	0UQ	A	S	1
FT	#HET	234	 230 	GLY	A	1	501 	0UQ	A	B	6
FT	#HET	235	 231 	THR	A	1	501 	0UQ	A	S	2
FT	#HET	236	 232 	THR	A	1	501 	0UQ	A	S	1
FT	#HET	400	 396 	HIS	A	2	502 	ZN	A	S	4
FT	#HET	402	 398 	HIS	A	2	502 	ZN	A	S	3
FT	DISORDER	1	2
FT	DISORDER	162	167
FT	DISORDER	403	404
CC	SEQUENCE	394 AA (ATOM);
CC	FVEMVDNLRG KSGQGYYVEM TVGSPPQTLN ILVDTGSSNF AVGAAPHPFL HRYYQRQLSS
CC	TYRDLRKGVY VPYTQGKWEG ELGTDLVSIP HGPNVTVRAN IAAITESDKF FINGSNWEGI
CC	LGLAYAEIAR PDDSLEPFFD SLVKQTHVPN LFSLQLCGAS EVLASVGGSM IIGGIDHSLY
CC	TGSLWYTPIR REWYYEVIIV RVEINGQDLK MDCKEYNYDK SIVDSGTTNL RLPKKVFEAA
CC	VKSIKAASST EKFPDGFWLG EQLVCWQAGT TPWNIFPVIS LYLMGEVTNQ SFRITILPQQ
CC	YLRPVEDVAT SQDDCYKFAI SQSSTGTVMG AVIMEGFYVV FDRARKRIGF AVSACHVHDE
CC	FRTAAVEGPF VTLDMEDCGY NIPQTDESRS HHHH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHP
CC	ATOM   --FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHP
CC	         ************************************************
CC	SEQRES FLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVR
CC	ATOM   FLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVR
CC	       **************************************************
CC	SEQRES ANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHV
CC	ATOM   ANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHV
CC	       **************************************************
CC	SEQRES PNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRRE
CC	ATOM   PNLFSLQLCGA------SEVLASVGGSMIIGGIDHSLYTGSLWYTPIRRE
CC	       ***********      *********************************
CC	SEQRES WYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVK
CC	ATOM   WYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVK
CC	       **************************************************
CC	SEQRES SIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSF
CC	ATOM   SIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSF
CC	       **************************************************
CC	SEQRES RITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFD
CC	ATOM   RITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFD
CC	       **************************************************
CC	SEQRES RARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESRSHH
CC	ATOM   RARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESRSHH
CC	       **************************************************
CC	SEQRES HHHH
CC	ATOM   HH--
CC	       **  
SQ	SEQUENCE	404 AA;      MW;         CN;
	GSFVEMVDNL RGKSGQGYYV EMTVGSPPQT LNILVDTGSS NFAVGAAPHP FLHRYYQRQL
	SSTYRDLRKG VYVPYTQGKW EGELGTDLVS IPHGPNVTVR ANIAAITESD KFFINGSNWE
	GILGLAYAEI ARPDDSLEPF FDSLVKQTHV PNLFSLQLCG AGFPLNQSEV LASVGGSMII
	GGIDHSLYTG SLWYTPIRRE WYYEVIIVRV EINGQDLKMD CKEYNYDKSI VDSGTTNLRL
	PKKVFEAAVK SIKAASSTEK FPDGFWLGEQ LVCWQAGTTP WNIFPVISLY LMGEVTNQSF
	RITILPQQYL RPVEDVATSQ DDCYKFAISQ SSTGTVMGAV IMEGFYVVFD RARKRIGFAV
	SACHVHDEFR TAAVEGPFVT LDMEDCGYNI PQTDESRSHH HHHH
//