ID	4FIAA	STANDARD;	PRT;	456	AA.
DT	CONVERTED FROM PDB (SEQRES) 4FIA
DE	Cholesterol 24-hydroxylase
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.100
CC	R-Factor	0.211
FT	#HET	32	  80 	PHE	A	2	601 	0U9	A	S	12
FT	#HET	32	  80 	PHE	A	3	602 	198	A	S	12
FT	#HET	52	 100 	THR	A	4	603 	GOL	A	A	8
FT	#HET	53	 101 	LYS	A	4	603 	GOL	A	A	3
FT	#HET	56	 104 	LYS	A	1	600 	HEM	A	S	6
FT	#HET	61	 109 	TYR	A	1	600 	HEM	A	S	5
FT	#HET	61	 109 	TYR	A	2	601 	0U9	A	S	1
FT	#HET	61	 109 	TYR	A	3	602 	198	A	S	1
FT	#HET	64	 112 	LEU	A	2	601 	0U9	A	S	6
FT	#HET	64	 112 	LEU	A	3	602 	198	A	S	5
FT	#HET	73	 121 	PHE	A	2	601 	0U9	A	S	2
FT	#HET	73	 121 	PHE	A	3	602 	198	A	S	2
FT	#HET	77	 125 	LEU	A	1	600 	HEM	A	A	8
FT	#HET	78	 126 	VAL	A	1	600 	HEM	A	A	5
FT	#HET	78	 126 	VAL	A	2	601 	0U9	A	S	2
FT	#HET	78	 126 	VAL	A	3	602 	198	A	S	2
FT	#HET	83	 131 	TYR	A	4	603 	GOL	A	S	1
FT	#HET	86	 134 	TRP	A	1	600 	HEM	A	S	7
FT	#HET	90	 138 	ARG	A	1	600 	HEM	A	S	4
FT	#HET	97	 145 	PHE	A	1	600 	HEM	A	S	1
FT	#HET	174	 222 	ILE	A	2	601 	0U9	A	S	1
FT	#HET	174	 222 	ILE	A	3	602 	198	A	S	1
FT	#HET	178	 226 	ARG	A	2	601 	0U9	A	S	2
FT	#HET	178	 226 	ARG	A	3	602 	198	A	S	2
FT	#HET	251	 299 	PHE	A	1	600 	HEM	A	S	2
FT	#HET	253	 301 	ILE	A	2	601 	0U9	A	S	1
FT	#HET	253	 301 	ILE	A	3	602 	198	A	S	1
FT	#HET	254	 302 	ALA	A	1	600 	HEM	A	B	7
FT	#HET	254	 302 	ALA	A	2	601 	0U9	A	A	4
FT	#HET	254	 302 	ALA	A	3	602 	198	A	A	5
FT	#HET	255	 303 	GLY	A	1	600 	HEM	A	B	7
FT	#HET	258	 306 	THR	A	1	600 	HEM	A	A	12
FT	#HET	258	 306 	THR	A	2	601 	0U9	A	S	1
FT	#HET	258	 306 	THR	A	3	602 	198	A	S	1
FT	#HET	259	 307 	SER	A	1	600 	HEM	A	A	5
FT	#HET	262	 310 	HIS	A	1	600 	HEM	A	S	2
FT	#HET	319	 367 	ALA	A	1	600 	HEM	A	S	1
FT	#HET	320	 368 	TRP	A	2	601 	0U9	A	S	8
FT	#HET	320	 368 	TRP	A	3	602 	198	A	S	7
FT	#HET	321	 369 	GLY	A	2	601 	0U9	A	B	5
FT	#HET	321	 369 	GLY	A	3	602 	198	A	B	5
FT	#HET	322	 370 	THR	A	1	600 	HEM	A	S	4
FT	#HET	323	 371 	PHE	A	2	601 	0U9	A	S	2
FT	#HET	323	 371 	PHE	A	3	602 	198	A	S	2
FT	#HET	381	 429 	PRO	A	1	600 	HEM	A	B	3
FT	#HET	382	 430 	PHE	A	1	600 	HEM	A	A	11
FT	#HET	383	 431 	SER	A	1	600 	HEM	A	A	2
FT	#HET	387	 435 	ARG	A	1	600 	HEM	A	A	7
FT	#HET	388	 436 	SER	A	1	600 	HEM	A	B	2
FT	#HET	389	 437 	CYS	A	1	600 	HEM	A	A	19
FT	#HET	390	 438 	ILE	A	1	600 	HEM	A	A	5
FT	#HET	391	 439 	GLY	A	1	600 	HEM	A	B	2
FT	#HET	394	 442 	PHE	A	1	600 	HEM	A	S	2
FT	#HET	395	 443 	ALA	A	1	600 	HEM	A	S	3
FT	#HET	398	 446 	GLU	A	1	600 	HEM	A	S	1
FT	#HET	424	 472 	GLU	A	2	601 	0U9	A	S	1
FT	#HET	424	 472 	GLU	A	3	602 	198	A	S	1
FT	#HET	425	 473 	GLN	A	2	601 	0U9	A	B	1
FT	#HET	425	 473 	GLN	A	3	602 	198	A	B	1
FT	#HET	426	 474 	ALA	A	2	601 	0U9	A	A	10
FT	#HET	426	 474 	ALA	A	3	602 	198	A	A	9
FT	#HET	427	 475 	THR	A	2	601 	0U9	A	S	2
FT	#HET	427	 475 	THR	A	3	602 	198	A	S	2
FT	DISORDER	1	8
FT	DISORDER	181	187
FT	DISORDER	442	456
CC	SEQUENCE	426 AA (ATOM);
CC	GRVLQDVFLD WAKKYGPVVR VNVFHKTSVI VTSPESVKKF LMSTKYNKDS KMYRALQTVF
CC	GERLFGQGLV SECNYERWHK QRRVIDLAFS RSSLVSLMET FNEKAEQLVE ILEAKADGQT
CC	PVSMQDMLTY TAMDILAKAA FGMETSMLLG AQKPLSQAVK LMLEGITASR NTKRKQLREV
CC	RESIRFLRQV GRDWVQRRRE ALKRGEEVPA DILTQILKAE EGAQDDEGLL DNFVTFFIAG
CC	HETSANHLAF TVMELSRQPE IVARLQAEVD EVIGSKRYLD FEDLGRLQYL SQVLKESLRL
CC	YPPAWGTFRL LEEETLIDGV RVPGNTPLLF STYVMGRMDT YFEDPLTFNP DRFGPGAPKP
CC	RFTYFPFSLG HRSCIGQQFA QMEVKVVMAK LLQRLEFRLV PGQRFGLQEQ ATLKPLDPVL
CC	CTLRPR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKDEVGGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLM
CC	ATOM   --------GRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLM
CC	               ******************************************
CC	SEQRES STKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRS
CC	ATOM   STKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRS
CC	       **************************************************
CC	SEQRES SLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFG
CC	ATOM   SLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFG
CC	       **************************************************
CC	SEQRES METSMLLGAQKPLSQAVKLMLEGITASRNTLAKFLPGKRKQLREVRESIR
CC	ATOM   METSMLLGAQKPLSQAVKLMLEGITASRNT-------KRKQLREVRESIR
CC	       ******************************       *************
CC	SEQRES FLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVT
CC	ATOM   FLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVT
CC	       **************************************************
CC	SEQRES FFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLG
CC	ATOM   FFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLG
CC	       **************************************************
CC	SEQRES RLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVM
CC	ATOM   RLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVM
CC	       **************************************************
CC	SEQRES GRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVK
CC	ATOM   GRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVK
CC	       **************************************************
CC	SEQRES VVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRGWQPAPPPP
CC	ATOM   VVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPR---------
CC	       *****************************************         
CC	SEQRES PCHHHH
CC	ATOM   ------
CC	             
SQ	SEQUENCE	456 AA;      MW;         CN;
	MAKKDEVGGR VLQDVFLDWA KKYGPVVRVN VFHKTSVIVT SPESVKKFLM STKYNKDSKM
	YRALQTVFGE RLFGQGLVSE CNYERWHKQR RVIDLAFSRS SLVSLMETFN EKAEQLVEIL
	EAKADGQTPV SMQDMLTYTA MDILAKAAFG METSMLLGAQ KPLSQAVKLM LEGITASRNT
	LAKFLPGKRK QLREVRESIR FLRQVGRDWV QRRREALKRG EEVPADILTQ ILKAEEGAQD
	DEGLLDNFVT FFIAGHETSA NHLAFTVMEL SRQPEIVARL QAEVDEVIGS KRYLDFEDLG
	RLQYLSQVLK ESLRLYPPAW GTFRLLEEET LIDGVRVPGN TPLLFSTYVM GRMDTYFEDP
	LTFNPDRFGP GAPKPRFTYF PFSLGHRSCI GQQFAQMEVK VVMAKLLQRL EFRLVPGQRF
	GLQEQATLKP LDPVLCTLRP RGWQPAPPPP PCHHHH
//