ID	4FCOA	STANDARD;	PRT;	433	AA.
DT	CONVERTED FROM PDB (SEQRES) 4FCO
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.760
CC	R-Factor	0.164
FT	#HET	51	  59 	GLY	A	4	504 	0U4	A	B	2
FT	#HET	52	  60 	GLN	A	4	504 	0U4	A	B	4
FT	#HET	53	  61 	GLY	A	4	504 	0U4	A	B	8
FT	#HET	62	  70 	SER	A	3	503 	SO4	A	A	7
FT	#HET	63	  71 	PRO	A	3	503 	SO4	A	A	2
FT	#HET	70	  78 	LEU	A	4	504 	0U4	A	S	3
FT	#HET	72	  80 	ASP	A	4	504 	0U4	A	S	8
FT	#HET	74	  82 	GLY	A	4	504 	0U4	A	B	7
FT	#HET	75	  83 	SER	A	4	504 	0U4	A	A	3
FT	#HET	87	  95 	PHE	A	5	505 	URE	A	S	4
FT	#HET	91	  99 	TYR	A	1	501 	SO4	A	S	7
FT	#HET	93	 101 	GLN	A	1	501 	SO4	A	S	6
FT	#HET	95	 103 	GLN	A	1	501 	SO4	A	S	5
FT	#HET	98	 106 	SER	A	3	503 	SO4	A	S	5
FT	#HET	101	 109 	ARG	A	2	502 	SO4	A	S	10
FT	#HET	111	 119 	TYR	A	4	504 	0U4	A	S	8
FT	#HET	112	 120 	THR	A	4	504 	0U4	A	A	9
FT	#HET	113	 121 	GLN	A	4	504 	0U4	A	A	18
FT	#HET	148	 156 	PHE	A	4	504 	0U4	A	A	6
FT	#HET	155	 163 	TRP	A	4	504 	0U4	A	S	3
FT	#HET	158	 166 	ILE	A	4	504 	0U4	A	S	3
FT	#HET	238	 246 	TYR	A	4	504 	0U4	A	S	2
FT	#HET	264	 272 	LYS	A	4	504 	0U4	A	S	3
FT	#HET	266	 274 	ILE	A	4	504 	0U4	A	S	1
FT	#HET	268	 276 	ASP	A	4	504 	0U4	A	S	8
FT	#HET	269	 277 	SER	A	4	504 	0U4	A	B	2
FT	#HET	270	 278 	GLY	A	4	504 	0U4	A	B	13
FT	#HET	271	 279 	THR	A	4	504 	0U4	A	S	6
FT	#HET	272	 280 	THR	A	4	504 	0U4	A	A	17
FT	#HET	273	 281 	ASN	A	4	504 	0U4	A	A	13
FT	#HET	275	 283 	ARG	A	4	504 	0U4	A	S	5
FT	#HET	347	 355 	ARG	A	4	504 	0U4	A	S	1
FT	#HET	365	 373 	SER	A	4	504 	0U4	A	S	1
FT	#HET	369	 377 	THR	A	4	504 	0U4	A	A	13
FT	#HET	375	 383 	ALA	A	4	504 	0U4	A	S	2
FT	DISORDER	1	36
FT	DISORDER	198	209
FT	DISORDER	351	353
FT	DISORDER	426	433
CC	SEQUENCE	374 AA (ATOM);
CC	GSFVEMVDNL RGKSGQGYYV EMTVGSPPQT LNILVDTGSS NFAVGAAPHP FLHRYYQRQL
CC	SSTYRDLRKG VYVPYTQGAW AGELGTDLVS IPHGPNVTVR ANIAAITESD KFFINGSNWE
CC	GILGLAYAEI ARPDDSLEPF FDSLVKQTHV PNLFSLQLCG AVGGSMIIGG IDHSLYTGSL
CC	WYTPIRREWY YEVIIVRVEI NGQDLKMDCK EYNYDKSIVD SGTTNLRLPK KVFEAAVKSI
CC	KAASSTEKFP DGFWLGEQLV CWQAGTTPWN IFPVISLYLM GEVTNQSFRI TILPQQYLRP
CC	VETSQDDCYK FAISQSSTGT VMGAVIMEGF YVVFDRARKR IGFAVSACHV HDEFRTAAVE
CC	GPFVTLDMED CGYN
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MGSSHHHHHHSAGENLYFQGTLPRETDEEPEEPGRRGSFVEMVDNLRGKS
CC	ATOM   ------------------------------------GSFVEMVDNLRGKS
CC	                                           **************
CC	SEQRES GQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTY
CC	ATOM   GQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTY
CC	       **************************************************
CC	SEQRES RDLRKGVYVPYTQGAWAGELGTDLVSIPHGPNVTVRANIAAITESDKFFI
CC	ATOM   RDLRKGVYVPYTQGAWAGELGTDLVSIPHGPNVTVRANIAAITESDKFFI
CC	       **************************************************
CC	SEQRES NGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFP
CC	ATOM   NGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGA---
CC	       ***********************************************   
CC	SEQRES LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEING
CC	ATOM   ---------VGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEING
CC	                *****************************************
CC	SEQRES QDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDG
CC	ATOM   QDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDG
CC	       **************************************************
CC	SEQRES FWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVE
CC	ATOM   FWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVE
CC	       **************************************************
CC	SEQRES DVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACH
CC	ATOM   ---TSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACH
CC	          ***********************************************
CC	SEQRES VHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST
CC	ATOM   VHDEFRTAAVEGPFVTLDMEDCGYN--------
CC	       *************************        
SQ	SEQUENCE	433 AA;      MW;         CN;
	MGSSHHHHHH SAGENLYFQG TLPRETDEEP EEPGRRGSFV EMVDNLRGKS GQGYYVEMTV
	GSPPQTLNIL VDTGSSNFAV GAAPHPFLHR YYQRQLSSTY RDLRKGVYVP YTQGAWAGEL
	GTDLVSIPHG PNVTVRANIA AITESDKFFI NGSNWEGILG LAYAEIARPD DSLEPFFDSL
	VKQTHVPNLF SLQLCGAGFP LNQSEVLASV GGSMIIGGID HSLYTGSLWY TPIRREWYYE
	VIIVRVEING QDLKMDCKEY NYDKSIVDSG TTNLRLPKKV FEAAVKSIKA ASSTEKFPDG
	FWLGEQLVCW QAGTTPWNIF PVISLYLMGE VTNQSFRITI LPQQYLRPVE DVATSQDDCY
	KFAISQSSTG TVMGAVIMEG FYVVFDRARK RIGFAVSACH VHDEFRTAAV EGPFVTLDME
	DCGYNIPQTD EST
//