ID	4FCDA	STANDARD;	PRT;	345	AA.
DT	CONVERTED FROM PDB (SEQRES) 4FCD
DE	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.020
CC	R-Factor	0.259
FT	#SUB	23	 457 	ARG	A	313	 747 	ASP	B	Protein	S	1
FT	#SUB	23	 457 	ARG	A	316	 750 	SER	B	Protein	S	4
FT	#SUB	32	 466 	HIS	A	323	 757 	ARG	B	Protein	S	8
FT	#SUB	37	 471 	PRO	A	312	 746 	ARG	B	Protein	B	5
FT	#SUB	37	 471 	PRO	A	315	 749 	LEU	B	Protein	S	2
FT	#SUB	38	 472 	PHE	A	312	 746 	ARG	B	Protein	S	3
FT	#SUB	40	 474 	ASN	A	312	 746 	ARG	B	Protein	S	1
FT	#SUB	41	 475 	MET	A	312	 746 	ARG	B	Protein	S	1
FT	#SUB	237	 671 	LEU	A	283	 717 	LEU	B	Protein	S	1
FT	#SUB	237	 671 	LEU	A	319	 753 	GLU	B	Protein	S	1
FT	#SUB	237	 671 	LEU	A	322	 756 	ILE	B	Protein	S	1
FT	#SUB	237	 671 	LEU	A	323	 757 	ARG	B	Protein	S	1
FT	#SUB	238	 672 	TRP	A	280	 714 	GLN	B	Protein	S	1
FT	#SUB	239	 673 	PRO	A	280	 714 	GLN	B	Protein	S	3
FT	#SUB	239	 673 	PRO	A	283	 717 	LEU	B	Protein	S	1
FT	#SUB	240	 674 	VAL	A	287	 721 	ASN	B	Protein	S	1
FT	#HET	80	 514 	TYR	A	3	803 	0T6	A	S	2
FT	#HET	81	 515 	HIS	A	3	803 	0T6	A	S	2
FT	#HET	85	 519 	HIS	A	1	801 	ZN	A	S	3
FT	#HET	119	 553 	HIS	A	1	801 	ZN	A	S	3
FT	#HET	120	 554 	ASP	A	1	801 	ZN	A	S	3
FT	#HET	120	 554 	ASP	A	2	802 	MG	A	S	3
FT	#HET	148	 582 	GLU	A	2	802 	MG	A	S	1
FT	#HET	230	 664 	ASP	A	1	801 	ZN	A	S	3
FT	#HET	230	 664 	ASP	A	3	803 	0T6	A	S	1
FT	#HET	231	 665 	LEU	A	3	803 	0T6	A	A	3
FT	#HET	233	 667 	SER	A	3	803 	0T6	A	S	1
FT	#HET	248	 682 	ILE	A	3	803 	0T6	A	S	3
FT	#HET	249	 683 	TYR	A	3	803 	0T6	A	S	2
FT	#HET	252	 686 	PHE	A	3	803 	0T6	A	S	7
FT	#HET	269	 703 	MET	A	3	803 	0T6	A	S	3
FT	#HET	281	 715 	GLY	A	3	803 	0T6	A	B	1
FT	#HET	282	 716 	GLN	A	3	803 	0T6	A	S	8
FT	#HET	285	 719 	PHE	A	3	803 	0T6	A	S	29
FT	DISORDER	1	3
FT	DISORDER	326	345
CC	SEQUENCE	322 AA (ATOM);
CC	MSICTSEEWQ GLMQFTLPVR LCKEIELFHF DIGPFENMWP GIFVYMVHRS CGTSCFELEK
CC	LCRFIMSVKK NYRRVPYHNW KHAVTVAHCM YAILQNNHTL FTDLERKGLL IACLCHDLDH
CC	RGFSNSYLQK FDHPLAALYS TSTMEQHHFS QTVSILQLEG HNIFSTLSSS EYEQVLEIIR
CC	KAIIATDLAL YFGNRKQLEE MYQTGSLNLN NQSHRDRVIG LMMTACDLCS VTKLWPVTKL
CC	TANDIYAEFW AEGDEMKKLG IQPIPMMDRD KKDEVPQGQL GFYNAVAIPC YTTLTQILPP
CC	TEPLLKACRD NLSQWEKVIR GE
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSHMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMV
CC	ATOM   ---MSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMV
CC	          ***********************************************
CC	SEQRES HRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNN
CC	ATOM   HRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNN
CC	       **************************************************
CC	SEQRES HTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQH
CC	ATOM   HTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQH
CC	       **************************************************
CC	SEQRES HFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQ
CC	ATOM   HFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQ
CC	       **************************************************
CC	SEQRES LEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYA
CC	ATOM   LEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYA
CC	       **************************************************
CC	SEQRES EFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQI
CC	ATOM   EFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQI
CC	       **************************************************
CC	SEQRES LPPTEPLLKACRDNLSQWEKVIRGEETATWISSPSVAQKAAASED
CC	ATOM   LPPTEPLLKACRDNLSQWEKVIRGE--------------------
CC	       *************************                    
SQ	SEQUENCE	345 AA;      MW;         CN;
	GSHMSICTSE EWQGLMQFTL PVRLCKEIEL FHFDIGPFEN MWPGIFVYMV HRSCGTSCFE
	LEKLCRFIMS VKKNYRRVPY HNWKHAVTVA HCMYAILQNN HTLFTDLERK GLLIACLCHD
	LDHRGFSNSY LQKFDHPLAA LYSTSTMEQH HFSQTVSILQ LEGHNIFSTL SSSEYEQVLE
	IIRKAIIATD LALYFGNRKQ LEEMYQTGSL NLNNQSHRDR VIGLMMTACD LCSVTKLWPV
	TKLTANDIYA EFWAEGDEMK KLGIQPIPMM DRDKKDEVPQ GQLGFYNAVA IPCYTTLTQI
	LPPTEPLLKA CRDNLSQWEK VIRGEETATW ISSPSVAQKA AASED
//
ID	4FCDB	STANDARD;	PRT;	345	AA.
DT	CONVERTED FROM PDB (SEQRES) 4FCD
DE	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.020
CC	R-Factor	0.259
FT	#SUB	280	 714 	GLN	B	238	 672 	TRP	A	Protein	S	1
FT	#SUB	280	 714 	GLN	B	239	 673 	PRO	A	Protein	A	3
FT	#SUB	283	 717 	LEU	B	237	 671 	LEU	A	Protein	S	1
FT	#SUB	283	 717 	LEU	B	239	 673 	PRO	A	Protein	S	1
FT	#SUB	287	 721 	ASN	B	240	 674 	VAL	A	Protein	S	1
FT	#SUB	312	 746 	ARG	B	37	 471 	PRO	A	Protein	S	5
FT	#SUB	312	 746 	ARG	B	38	 472 	PHE	A	Protein	S	3
FT	#SUB	312	 746 	ARG	B	40	 474 	ASN	A	Protein	S	1
FT	#SUB	312	 746 	ARG	B	41	 475 	MET	A	Protein	S	1
FT	#SUB	313	 747 	ASP	B	23	 457 	ARG	A	Protein	S	1
FT	#SUB	315	 749 	LEU	B	37	 471 	PRO	A	Protein	S	2
FT	#SUB	316	 750 	SER	B	23	 457 	ARG	A	Protein	S	4
FT	#SUB	319	 753 	GLU	B	237	 671 	LEU	A	Protein	S	1
FT	#SUB	322	 756 	ILE	B	237	 671 	LEU	A	Protein	S	1
FT	#SUB	323	 757 	ARG	B	32	 466 	HIS	A	Protein	S	8
FT	#SUB	323	 757 	ARG	B	237	 671 	LEU	A	Protein	S	1
FT	#HET	80	 514 	TYR	B	6	803 	0T6	B	S	2
FT	#HET	81	 515 	HIS	B	6	803 	0T6	B	S	3
FT	#HET	85	 519 	HIS	B	4	801 	ZN	B	S	3
FT	#HET	119	 553 	HIS	B	4	801 	ZN	B	S	3
FT	#HET	119	 553 	HIS	B	5	802 	MG	B	S	1
FT	#HET	120	 554 	ASP	B	4	801 	ZN	B	S	3
FT	#HET	120	 554 	ASP	B	5	802 	MG	B	S	3
FT	#HET	230	 664 	ASP	B	4	801 	ZN	B	S	3
FT	#HET	230	 664 	ASP	B	6	803 	0T6	B	S	1
FT	#HET	231	 665 	LEU	B	6	803 	0T6	B	S	3
FT	#HET	248	 682 	ILE	B	6	803 	0T6	B	S	4
FT	#HET	249	 683 	TYR	B	6	803 	0T6	B	S	2
FT	#HET	252	 686 	PHE	B	6	803 	0T6	B	S	8
FT	#HET	269	 703 	MET	B	6	803 	0T6	B	S	3
FT	#HET	281	 715 	GLY	B	6	803 	0T6	B	B	1
FT	#HET	282	 716 	GLN	B	6	803 	0T6	B	S	2
FT	#HET	285	 719 	PHE	B	6	803 	0T6	B	S	23
FT	DISORDER	1	2
FT	DISORDER	131	143
FT	DISORDER	326	345
CC	SEQUENCE	310 AA (ATOM);
CC	HMSICTSEEW QGLMQFTLPV RLCKEIELFH FDIGPFENMW PGIFVYMVHR SCGTSCFELE
CC	KLCRFIMSVK KNYRRVPYHN WKHAVTVAHC MYAILQNNHT LFTDLERKGL LIACLCHDLD
CC	HRGFSNSYTS TMEQHHFSQT VSILQLEGHN IFSTLSSSEY EQVLEIIRKA IIATDLALYF
CC	GNRKQLEEMY QTGSLNLNNQ SHRDRVIGLM MTACDLCSVT KLWPVTKLTA NDIYAEFWAE
CC	GDEMKKLGIQ PIPMMDRDKK DEVPQGQLGF YNAVAIPCYT TLTQILPPTE PLLKACRDNL
CC	SQWEKVIRGE
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSHMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMV
CC	ATOM   --HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMV
CC	         ************************************************
CC	SEQRES HRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNN
CC	ATOM   HRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNN
CC	       **************************************************
CC	SEQRES HTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQH
CC	ATOM   HTLFTDLERKGLLIACLCHDLDHRGFSNSY-------------TSTMEQH
CC	       ******************************             *******
CC	SEQRES HFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQ
CC	ATOM   HFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQ
CC	       **************************************************
CC	SEQRES LEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYA
CC	ATOM   LEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYA
CC	       **************************************************
CC	SEQRES EFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQI
CC	ATOM   EFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQI
CC	       **************************************************
CC	SEQRES LPPTEPLLKACRDNLSQWEKVIRGEETATWISSPSVAQKAAASED
CC	ATOM   LPPTEPLLKACRDNLSQWEKVIRGE--------------------
CC	       *************************                    
SQ	SEQUENCE	345 AA;      MW;         CN;
	GSHMSICTSE EWQGLMQFTL PVRLCKEIEL FHFDIGPFEN MWPGIFVYMV HRSCGTSCFE
	LEKLCRFIMS VKKNYRRVPY HNWKHAVTVA HCMYAILQNN HTLFTDLERK GLLIACLCHD
	LDHRGFSNSY LQKFDHPLAA LYSTSTMEQH HFSQTVSILQ LEGHNIFSTL SSSEYEQVLE
	IIRKAIIATD LALYFGNRKQ LEEMYQTGSL NLNNQSHRDR VIGLMMTACD LCSVTKLWPV
	TKLTANDIYA EFWAEGDEMK KLGIQPIPMM DRDKKDEVPQ GQLGFYNAVA IPCYTTLTQI
	LPPTEPLLKA CRDNLSQWEK VIRGEETATW ISSPSVAQKA AASED
//