ID	4EWOA	STANDARD;	PRT;	386	AA.
DT	CONVERTED FROM PDB (SEQRES) 4EWO
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.800
CC	R-Factor	0.181
FT	#HET	31	  78 	LEU	A	1	501 	996	A	S	2
FT	#HET	33	  80 	ASP	A	1	501 	996	A	S	9
FT	#HET	35	  82 	GLY	A	1	501 	996	A	B	8
FT	#HET	36	  83 	SER	A	1	501 	996	A	S	2
FT	#HET	70	 117 	VAL	A	1	501 	996	A	S	1
FT	#HET	71	 118 	PRO	A	1	501 	996	A	B	2
FT	#HET	72	 119 	TYR	A	1	501 	996	A	A	9
FT	#HET	73	 120 	THR	A	1	501 	996	A	A	8
FT	#HET	109	 156 	PHE	A	1	501 	996	A	A	4
FT	#HET	116	 163 	TRP	A	1	501 	996	A	S	3
FT	#HET	119	 166 	ILE	A	1	501 	996	A	S	2
FT	#HET	127	 174 	ILE	A	1	501 	996	A	A	2
FT	#HET	129	 176 	ARG	A	1	501 	996	A	S	2
FT	#HET	199	 246 	TYR	A	1	501 	996	A	S	12
FT	#HET	229	 276 	ASP	A	1	501 	996	A	S	8
FT	#HET	231	 278 	GLY	A	1	501 	996	A	B	8
FT	#HET	232	 279 	THR	A	1	501 	996	A	S	3
FT	#HET	236	 283 	ARG	A	1	501 	996	A	S	1
FT	#HET	330	 377 	THR	A	1	501 	996	A	S	2
FT	DISORDER	160	168
CC	SEQUENCE	377 AA (ATOM);
CC	VEMVDNLRGK SGQGYYVEMT VGSPPQTLNI LVDTGSSNFA VGAAPHPFLH RYYQRQLSST
CC	YRDLRKGVYV PYTQGKWEGE LGTDLVSIPH GPNVTVRANI AAITESDKFF INGSNWEGIL
CC	GLAYAEIARP DDSLEPFFDS LVKQTHVPNL FSLQLCGAGA SVGGSMIIGG IDHSLYTGSL
CC	WYTPIRREWY YEVIIVRVEI NGQDLKMDCK EYNYDKSIVD SGTTNLRLPK KVFEAAVKSI
CC	KAASSTEKFP DGFWLGEQLV CWQAGTTPWN IFPVISLYLM GEVTNQSFRI TILPQQYLRP
CC	VEDVATSQDD CYKFAISQSS TGTVMGAVIM EGFYVVFDRA RKRIGFAVSA CHVHDEFRTA
CC	AVEGPFVTLD MEDCGYN
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLH
CC	ATOM   VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLH
CC	       **************************************************
CC	SEQRES RYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANI
CC	ATOM   RYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANI
CC	       **************************************************
CC	SEQRES AAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNL
CC	ATOM   AAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNL
CC	       **************************************************
CC	SEQRES FSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYY
CC	ATOM   FSLQLCGAG---------ASVGGSMIIGGIDHSLYTGSLWYTPIRREWYY
CC	       *********         ********************************
CC	SEQRES EVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIK
CC	ATOM   EVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIK
CC	       **************************************************
CC	SEQRES AASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
CC	ATOM   AASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
CC	       **************************************************
CC	SEQRES ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRAR
CC	ATOM   ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRAR
CC	       **************************************************
CC	SEQRES KRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN
CC	ATOM   KRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN
CC	       ************************************
SQ	SEQUENCE	386 AA;      MW;         CN;
	VEMVDNLRGK SGQGYYVEMT VGSPPQTLNI LVDTGSSNFA VGAAPHPFLH RYYQRQLSST
	YRDLRKGVYV PYTQGKWEGE LGTDLVSIPH GPNVTVRANI AAITESDKFF INGSNWEGIL
	GLAYAEIARP DDSLEPFFDS LVKQTHVPNL FSLQLCGAGF PLNQSEVLAS VGGSMIIGGI
	DHSLYTGSLW YTPIRREWYY EVIIVRVEIN GQDLKMDCKE YNYDKSIVDS GTTNLRLPKK
	VFEAAVKSIK AASSTEKFPD GFWLGEQLVC WQAGTTPWNI FPVISLYLMG EVTNQSFRIT
	ILPQQYLRPV EDVATSQDDC YKFAISQSST GTVMGAVIME GFYVVFDRAR KRIGFAVSAC
	HVHDEFRTAA VEGPFVTLDM EDCGYN
//